May 2023 - Bmegradstudents-list

[Bmeroundtable-list] FW: Dr. Graham Fraser
by Gelfand, Johanna K 18 May '23

18 May '23

The Purdue Department of Health & Kinesiology is hosting Dr. Graham M. Fraser from the Memorial University of Newfoundland on May 31st (please see attached flyer). Graham utilizes intravital video microscopy to examine skeletal muscle capillary blood flow regulation. His recordings are astounding, as shown in this short video clip of the rat EDL muscle he posted on Twitter: https://twitter.com/DrGrahamFraser/status/1511080935718113289 Please share the flyer with people that might be interested. -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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GTA position available in Engineering Honors Program
by Siemers, Tammy R 18 May '23

18 May '23

Good Morning, For those of you that might be looking for funding this upcoming year, please see below. As with any outside activity, please check with your faculty advisor before moving forward with applying. Tammy From: Timothy M. Whalen <whalen(a)purdue.edu> Sent: Wednesday, May 17, 2023 4:47 PM To: Timothy M. Whalen <whalen(a)purdue.edu> Cc: Joseph Alan Lyon <lyonj(a)purdue.edu>; Brophy, Sean <sbrophy(a)purdue.edu>; Linnes, Jacqueline C <jlinnes(a)purdue.edu> Subject: GTA position available in Engineering Honors Program Hello: This is Tim Whalen -- I'm with the Engineering Honors Program here at Purdue. The Engineering Honors Program is looking to hire a Graduate Teaching Assistant to join the Instructional Team for the courses ENGR 16100 & ENGR 16200 for the upcoming academic year (Fall 2023/Spring 2024). I am writing you today to ask if you are aware of any graduate students in your program who might be suitable for this position. A little bit about the position: ENGR 16100/16200 is the honors version of the two course sequence taken by incoming FYE students. We teach engineering design principles, professional development, and basics of engineering analysis (specifically physics at the PHYS 17200 level). The students have been admitted into Purdue's Honors College or are members of our own Goss Scholars learning community, so we try to provide them with experiences that go above and beyond what students get in ENGR 13100/13200. GTAs in our course are responsible for helping the instructors run the course; in particular, they have a specific area of responsibility that they manage for us (running the course projects, managing our Peer TAs, etc.) Here are the qualifications we are looking for in our GTAs: * They must have an undergraduate degree in an engineering discipline (any discipline is fine, but must be in engineering). * We prefer that they have familiarity in as many of the following areas as possible, though we don't expect all of them: * programming in Python and/or MATLAB * CAD (any platform) * Microcomputers (e.g., Raspberry Pi) and/or microcontrollers (e.g., Arduino) * 3D printing * It is desirable (but not required) that they have prior teaching assistant experience. * If they happen to have a Purdue undergraduate degree, it is also desirable (but not required) that they are familiar with ENGR 16100/16200.

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Weldon Graduate Program Announcements May 17th, 2023
by Siemers, Tammy R 17 May '23

17 May '23

[4,354 Breaking News Photos and Premium High Res Pictures - Getty Images] Weldon Graduate Program Announcements May 17th, 2023 * Career and Internship Opportunities * UPCOMING IN-PERSON EVENT: LSE's Annual Scientific Vendor Expo * Graduate Professional Development Newsletter (May 12) * Food Trucks & Families Event | Monday, June 12th from 11:00am-2:00pm | Please RSVP! * Workshops and Deadlines * News from You Career and Internship Opportunities Internship Positions * Quality Engineering Co-op Fall 2023, Mammotome<https://jobs.danaher.com/global/en/job/DANAGLOBALR1241203EXTERNALENGLOBAL/Q…> * Intern, Medical Device, Curia<https://hcug.fa.us2.oraclecloud.com/hcmUI/CandidateExperience/en/sites/CX_2…> * Biomedical Engineer Intern, WuXi AppTec<https://www.linkedin.com/jobs/view/3600330250/?trackingId=dcJqxc8SsUWPV2%2B…> Postdoctoral Positions * NPA Website: https://careers.nationalpostdoc.org/jobs/ Full Time Positions * Engineer II, R&D, Boston Scientific<https://jobs.bostonscientific.com/job/Maple-Grove-Engineer-II%2C-R&D-MN-553…> * Design Assurance Engineer II, Boston Scientific<https://jobs.bostonscientific.com/job/Maple-Grove-Design-Assurance-Engineer…> * Development Engineer I, Zimmer Biomet<https://www.simplyhired.com/job/HNu3zQrx7-VAr6LHAMHty-BsRCd0LTuBbz8nlQ92xl6…> * R&D Engineer I, Abbott Laboratory<https://www.jobs.abbott/us/en/job/ABLAUS31056997ENUSEXTERNAL/R-D-Engineer-I…> * Computational Scientist, Protein Engineering, Scismic<https://scismic.com/jobs/PE-libraries?source=Indeed> * System Engineer I, GetiInge<https://careers.getinge.com/job/Streetsboro-System-Engineer-I-OH/826078001/…> * Clinical Engineer, Goldbelt<https://careers-goldbelt.icims.com/jobs/11422/job?utm_source=indeed_integra…> * Design Engineer, Glidewell Dental<https://jobs.jobvite.com/careers/glidewelldental/job/oiTenfww?__jvst=Job%20…> * Assistant/Associate Project Scientist, Drug Delivery, CoE, Berkeley<https://aprecruit.berkeley.edu/JPF03934> * Imaging Research Analyst, Biomedical Engineering and Imaging Institute, Mount Sinai<https://careers.mountsinai.org/jobs/2847452?lang=en-us&src=JB-10100> * Sr. Development Engineer, Nuvasive<https://nuvasive.avature.net/careers/JobDetail/Sr-Development-Engineer/1103…> * Principle Systems Engineer, Baxter<https://jobs.baxter.com/job/-/-/152/48767952832?src=JB-10420> * Sr. Systems Quality Assurance Engineer, Hologic<https://www.simplyhired.com/job/DD4FZEUsbCUhC53NC1bxd4fpN4k1gMAZYWPRLSY9261…> * Purdue Start-up Job Board<https://purduefoundry.com/jobs?utm_source=Foundry+Mailing+List&utm_campaign…>-Foundry Start Up Companies Looking to Hire * ACTS Career Center<https://careers.actscience.org/>-Association for Clinical and Translational Science * Academic Careers<https://academiccareers.com/> * Doc Jobs<https://www.docjobs.com/jobs/list/>-Jobs beyond traditional clinical and academic roles UPCOMING IN-PERSON EVENT: LSE's Annual Scientific Vendor Expo For the Researchers at: Purdue University Purdue Memorial Union, 1st Floor 101 North Grant Street Thursday, June 1, 2023 * 11:00AM - 1:00PM 35+ Vendors | Free Lunch | T-Shirts, Gifts & Raffles! Pre-Register & Avoid Registration Line: Click Here<https://fs18.formsite.com/lifescienceexhibits/showregistration/index.html> Bring your lab to enjoy the upcoming event and visit with the vendors we have listed below. Everyone will have a chance to play to win free door prizes, the new Lab Warrior T-Shirts or gift cards before you leave. Skip the line at the Registration Booth by Pre-Registering for the event: Click Here to Pre-Register<http://lifescienceexhibits.com/showinfo>! If you have any questions at all, please feel free to reach out to us. We look forward to a great Annual Research Supplier Product Show on campus! Exhibiting Companies ACD, a BioTechne company Across International LLC Agilent Technologies Azenta Life Science BioLegend Bioss Antibodies Dot Scientific, Inc. Eclipsebio Electron Microscopy Sciences Eppendorf GemPharmatech Genesee Scientific Gold Biotechnology Haier Biomedical INTEGRA Biosciences Integrated DNA Technologies MACHEREY-NAGEL Medchemexpress LLC Meso Scale Discovery Mettler-Toledo RAININ LLC Miltenyi Biotec Inc. New England Biolabs PHC Corporation of North America ProteinTech Group RayBiotech Life RPI SARSTEDT Shanghai Model Organisms Center Sino Biological US, Inc. The Jackson Laboratory Thermo Fisher Scientific VWR, Part of Avantor Kind Regards, Life Science Exhibits www.lifescienceexhibits.com/showinfo<http://www.lifescienceexhibits.com/showinfo> Graduate Professional Development Newsletter (May 12) Graduate Professional Development Newsletter (May 12)<https://mailimages.purdue.edu/vo/?FileID=fcd702a0-15a9-4c0f-acea-8954799874…> Food Trucks & Families Event | Monday, June 12th from 11:00am-2:00pm | Please RSVP! See attached What: Food Trucks & Families Event | Graduate Engineering Food Options Include: Food Trucks! * Crabby Mike's BBQ: * Choice of brisket (beef) or pulled pork barbecue sandwich * Choice of side (mac & cheese, loaded potato salad, cole slaw, or potato chips) * Drink * V's Delicacies: * Build-your-own-burrito bar (Chicken or Beef or Stuffed Red & Yellow Pepper) on flour tortillas * Rice, beans, scallions, jalapeños, sour cream, olives, roasted corn salad with peppers * Drink * Igloo Frozen Custard: * Flavored soft drinks, Root Beer floats * Dishes of frozen custard (Vanilla, Mint Chip, Lemon Blueberry, and Cookie Monster) * Pineapple Dole Whip * Toppings (Oreo, M&Ms, Gummy Worms, Sprinkles, Pecans, and Peanuts) When: Monday, June 12, 2023 Time: 11:00am - 2:00pm Location: Purdue Memorial Mall Activities for Families: Yard games, including cornhole bag toss, ladder ball, balloon artists, bubble station, face painting, and more! Cost: FREE! Other: Please RSVP<https://bit.ly/2023_CoE_SummerEvent> using the survey link by Monday, May 29th. Workshops and Deadlines Here are some upcoming workshops and deadlines more detailed information about the workshops will be sent out separately closer to the event. May 17th NSF Fellowship Workshop - Personal Statement (Register Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4086>) May 17th The Cover Letter (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4096>) May 17th NIH Fellowship F31 Info Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4087>) May 18th Postdoc Houston - Virtual Info Session for Prospective Postdocs (Register<https://www.postdochouston.org/>) May 18th Business Meal Etiquette (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4128>) May 18th NIH F32 and K99/R00 Info Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4088>) May 22nd Deadline to apply for Trailblazers in Engineering (TBE) Workshop (Apply Here<https://engineering.purdue.edu/Engr/Trailblazers/?utm_source=delivra&utm_me…>) May 22nd Boiler Up & Intervene Workshop (CARE<https://gspd.gosignmeup.com/public/Course/browse?courseid=4094>) May 22nd Preparing a Teaching Demonstration (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4147>) May 22nd Debt Management (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4135>) May 23rd Preparing for Academic Interviews (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4149>) May 24th NSF Fellowship Workshop - Research Statement (Register Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4090>) May 24th USDA AFRI Fellowship Info Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4089>) May 24th Preparing to Buy a House (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4137>) May 24th GRIP workshop: Citation Management with Zotero (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4133>) May 24th-25th Facilitating Entering Mentoring Workshop (CIMER<https://sites.google.com/wisc.edu/facilitatingenteringmentoring/home?pli=1>) May 25th Eating Right When Your Budget is Tight (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4143>) May 25th NSF Fellowship Help Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4097>) May 26th Credit Cards and Credit Scores (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4139>) May 29th Deadline to RSVP for Food Trucks & Families Event @ Purdue Memorial Mall (RSVP<https://purdue.ca1.qualtrics.com/jfe/form/SV_1S14irSJKuaT14y>) May 31st How to Find and Prepare for Fellowship Applications (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4102>) May 31st NSF Fellowship Help Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4099>) June 5th Publishing a Scientific Paper (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4091>) June 6th CARE-ing Support: Responding to Disclosures of Interpersonal Violence (CARE<https://gspd.gosignmeup.com/public/Course/browse?courseid=4100>) June 6th NDSEG (Defense Research) Fellowship Info Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4125>) June 6th Budgeting and Saving Money (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4141>) June 12th Food Trucks & Families Event @ Purdue Memorial Mall (RSVP<https://purdue.ca1.qualtrics.com/jfe/form/SV_1S14irSJKuaT14y>) June 14th RCR: Discipline-Specific Training (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4130>) June 14th NSF Fellowships - Getting Started (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4103>) June 14th GRIP workshop: Citation Management with Zotero (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4134>) June 15th Business Meal Etiquette (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4129>) June 15th Postdoc Grant Writing: Logic Flow and Methods (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4106>) June 15th NSF Fellowship Help Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4105>) June 19th Debt Management (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4136>) June 20th Fellowship Office Hour for Grad Students and Postdocs (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4107>) June 21st NSF Fellowships - Personal Statement (Grantsmanship) (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4104>) June 22nd Mentorship Training for Postdocs: Communication Between Mentors & Mentees (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4110>) June 22nd NSF Fellowship Help Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4108>) June 27th Preparing to Buy a House (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4138>) June 28th NSF Fellowship Workshop - Research Statement (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4111>) June 28th Credit Cards and Credit Scores (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4140>) June 29th NSF Fellowship Help Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4109>) July 6th NSF Fellowship Help Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4116>) July 7th Power & Control Workshop (CARE<https://gspd.gosignmeup.com/public/Course/browse?courseid=4101>) July 7th Postdoc Orientation (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4112>) July 14th RCR: Discipline-Specific Training (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4131>) July 18th Publishing a Scientific Paper (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4092>) July 18th NSF Fellowship Life Sciences Panel (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4113>) July 18th NSF Fellowship Physical and Computational Sciences Panel (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4118>) July 18th Fellowship Office Hour for Grad Students and Postdocs (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4117>) July 19th NSF Fellowship Engineering Panel (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4119>) July 19th NSF Fellowship Social Sciences and Education Panel (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4114>) July 20th NSF Fellowship Agriculture Panel (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4115>) July 20th Business Meal Etiquette (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4145>) July 20th NSF Fellowship Help Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4120>) July 24th Budgeting and Saving Money (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4142>) July 25th Computational Fellowships Info Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4126>) July 26th How to Find and Prepare for Fellowship Applications (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4121>) July 26th NDSEG (Defense Research) Fellowship Info Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4124>) July 27th Postdoc Grant Writing: All About NSF (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4123>) July 27th NSF Fellowship Help Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4122>) July 24th-25th Facilitating Entering Mentoring Workshop (CIMER<https://sites.google.com/wisc.edu/facilitatingenteringmentoring/home?pli=1>) News from You Please inform Tammy of honors, awards, or other accolades (to include having a paper published) you receive so that the Weldon School may recognize your accomplishments. Send the complete information - specific title and nature of the award, name of conference or event at which award was given, date of said event, photograph if available, etc. - to tsiemers(a)purdue.edu<mailto:tsiemers@purdue.edu>. Tammy Siemers She/Her Associate Director, Graduate Education Weldon School of Biomedical Engineering 206 S. Martin Jischke Drive, West Lafayette, IN 47907-2032 o: 765-496-0294 Achiever, Relator, Includer, Restorative, Developer [233FFCD4]<https://www.purdue.edu/?utm_source=signature&utm_medium=email&utm_campaign=…>

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[Bmeroundtable-list] BME Monday Roundtable on Tuesday - 5/16/23
by Gelfand, Johanna K 16 May '23

16 May '23

[cid:image003.jpg@01D987F6.7607FD80] BME Monday ROUNDTABLE May 16, 2023 DEPUTY HEAD'S NOTE I apologize for the lateness. Honoring our graduates, Purdue celebrated spring 2023 graduation last Friday and this past weekend with a record 9 graduation ceremonies. I wanted to find some time on Monday to gather information and do reflections. To many of us, last Friday and the past weekend has been a memorable one. To the faculty, isn't it one of the most rewarding things in your career to hood your students, which signifies the completion of their long and often frustrating journey of PhD research. I proudly hooded two of my PhD students on Sunday evening. At the Armory and the Elliot Hall of Music, I saw Sherry, Craig, Joseph, Vitaliy, Luis, and Elsje (I apologize if I missed anyone). I saw a number of our students on stage receiving their well-deserved diplomas. Congratulations to the major professors and the recent PhD alumni. We've all made it together finally! Yay! Professor Kathleen Howell, the Hsu Lo Distinguished Professor of Aeronautics and Astronautics in the College of Engineering at Purdue University was the Guest Speaker of the Ninth Division (for doctoral and master's degree recipients). In her speech, she quoted President John Kennedy's famous saying from his "We Choose the Moon" speech: "We choose to go to the moon in this decade and do the other things, not because they are easy, but because they are hard." Many research projects in biomedicine are what JFK referred to as "the other things". Our finest faculty and PhD students are doing those things, exactly because they are hard. So proud of you all. Congratulations on your accomplishments. Particularly to those recent PhD alumni, this may be the last Roundtable email you read. I wish you the best of luck in your future. Continue to choose great things in biomedicine to do because they are hard. Last weekend, it was also a memorable weekend for our graduating seniors. They will never forget the four years' education in one of the finest schools at one of the finest engineering colleges. Kudos to our faculty and graduate student mentors. You are a big reason they are who they are now, with your teaching and mentoring as someone introducing to them the wonderful profession of biomedical engineering, and more importantly, someone who was set as their role model for the past four years and the many years to come. On Saturday morning, the department hosted the graduates and their parents at a Commencement Reception here in the MJIS Atrium. I was unable to attend it. Tami, as an attendee, wrote the following: To honor our Weldon School graduates, we held our annual Senior Dinner and BME Commencement Reception this past week. Over 150 new alumni and their families joined in the celebrations. These students have successfully navigated some of the most challenging years in recent history (COVID, economic downturns, changing education landscape). We applaud them for their hard work and thank them for their contributions to the Weldon School over the years. All the best to our recent Graduates! I attended the graduation ceremony for our graduating seniors last Friday afternoon (Second Division). It was an exciting experience shaking so many hands with them (definitely record-setting in the number of handshakes in one day). I was particularly taken by the commencement speech given by our President Chiang on artificial intelligence, besides getting the laughs out of it (e.g., he joked about the speech was not written by ChatGPT. The AI version of the speech if asking ChatGPT, would read like a B- high school essay, a grammatically correct synthesis with little specificity, originality or humor). His speech called on all Boilermakers to lead in "sharpening the ability to doubt, debate and dissent" in world of AI. I thought a lot about it over the weekend. I could not find a better area than human health where we really need great ability to doubt, debate and dissent what AI will give us. And our school undoubtedly should be the frontrunner in enhancing such ability. How would a physician really trust AI in assisting their decision making? How would an aging-in-place elderly adult really benefit from an AI-enabled digital companion? How would an AI-enabled analytics module, when deployed by a healthcare organization, be made sure to not widen health disparities while driving up the organization's revenue? How we can ensure ethical, privacy-preserving ways to collect data from human when the AI is just thirsting for more and more data? Important MJIS Alerts Starting Tuesday, May 16th (NOTE new date!), Martin Jischke Drive will be CLOSED to all traffic. The university will be performing infrastructure repairs in the area. The street will be closed to traffic for most, if not all of the summer. When the street reopens, bike lanes will replace the on-street parking, although we do not currently have details/confirmation on the entire process yet. Stay tuned for additional details. Wednesday, May 17th and Thursday, May 18th: MJIS passenger elevator will be DOWN both days for much-needed repairs. Analog stairwells will still be fully functional. Week of May 22: Exterior washing of windows in MJIS will take place this week. If you feel like you're being watched, look out your windows to see if there is someone there. We don't know specifically what days they will be working on MJIS, but it will be this week. There will be lifts moving around the building, so please be aware and be careful. REMINDER: Purdue University is a NON-SMOKING campus. You are not permitted to smoke/vape in or around MJIS. There is a smoking area on the other side of Martin Jischke Drive, near the police station. Remember that the air intakes for the entire building are located externally. If you smoke on the sidewalk outside of MJIS, it is drawn into and distributed throughout the building! Don't do it! Here is a map of all the smoking areas on campus: https://www.purdue.edu/smokefree/Smoking_map.pdf The closest to MJIS is labeled "4" UPCOMING IMPORTANT DATES Week of May 15 Wed., May 17: BME Summer Seminar Series, 9:30 a.m., via Zoom. The BME Summer Seminar Series will run from May 17th - August 9th. The first week's speakers will be Ruhi Sharmin and Brendan Ball. Full schedule is attached. Fri., May 19: BME PhD Preliminary Exam Announcement for Shulan Xiao (K. Jayant, advisor), Everyone is invited to attend the presentation beginning at 11:00 a.m. in MJIS 2001 and via Zoom. Title: The Biophysical Basis of Sensory Feature Binding in Cortical Pyramidal Neurons. Upcoming Opportunity for Fun! Do you play a band instrument? Purdue Bands and Orchestras has just opened registration for the 2023 Purdue University Summer Band! This ensemble is open to all area musicians that are high school age and up. Participation in Purdue's Summer Band is FREE to all. We plan to begin rehearsals on Tuesday, June 20, and rehearse on Tuesday and Thursday afternoons from 4:00-5:30 PM in Hagle Hall, Room 178. Our concert will be held on Thursday, July 20, 6:30 PM at Columbian Park Memorial Island Amphitheater immediately prior to a performance by the Lafayette Citizens' Band. Register Here: https://docs.google.com/forms/d/e/1FAIpQLSd8v47EEuzyl070XPk4QyH0fIBflpdLywl… Upcoming important deadlines and info. Tues., May 23: BME PhD Defense Announcement for Mrugesh Krishna Parasa (Dr. Kevin Solomon, advisor). Everyone is invited to attend the public presentation beginning at 3:00 PM via Zoom. Title of the Thesis Research: Programmable Control of Protein Activity via Formation of Biomolecular Condensates in Bacteria. Thurs., May 25: Application Deadline for Trailblazers in Engineering workshop, to be held on the Purdue campus July 25-26. Trailblazers in Engineering (TBE) is a multi-day workshop focused on preparing future outstanding engineering scholars for future engineering faculty careers who are also committed to increase the success of underrepresented communities of engineers. Trailblazers in Engineering Fellows are selected not only for their outstanding scholarly achievements but also for their potential impact in expanding representation and diversity in engineering. See attached flyer for application instructions. Tues., May 30: C.R.A.S.E. (Civilian Response to Active Shooter Events) training is available through the Purdue University Police Department. Contact Sarah Clark (sclark32(a)purdue.edu<mailto:sclark32@purdue.edu>) to sign up for your 9:30, 1:30 or 5:30 session. All faculty and staff are encouraged to attend. For additional information see: https://www.purdue.edu/newsroom/purduetoday/releases/2023/Q2/pupd-to-offer-… Committee Updates Graduate Office Update Dear BME Faculty, Weldon BME PhD students performing research in one of these areas - cardiovascular devices, implantable biomaterials design, drug-delivery systems, or biochemical sensors - are eligible for nomination for the Ronald W. Dollens Scholarship. For the nomination, we will need from you a short description (less than 250 words) of an outstanding, current graduate student in your lab who is excelling in research performance and service to the department. In your description, please mention/include the following: * Student's year in the PhD program (1st year, 2nd year, etc.) * Brief description of outstanding research performance * Brief description of service to the department * Mention of recent awards, presentations made at conferences, papers authored, etc., that you think help describe the student's contributions * Student's CV Please send the nomination to tsiemers(a)purdue.edu<mailto:tsiemers@purdue.edu> by Sunday, May 21st. The Ronald W. Dollens Scholarships in Life Sciences will be awarded based on academic merit to two deserving graduate students in the Weldon School of Biomedical Engineering who meet the criteria and are selected. The scholarship award is $5,000 with half being awarded in the Fall 2023 semester and half in the Spring 2024 semester. If you have any questions, please don't hesitate to reach out. New Course for Fall 2023: BME 69500 Pediatric Medical Devices (CRN 14011). Details below. Research Update To safeguard our valuable work and bolster Weldon's standing, it is important that we exercise caution with predatory journals and "hidden" predatory journals. We are collaborating with the Purdue library to organize a session. Stay tuned. https://www.science.org/content/article/fast-growing-open-access-journals-s… https://retractionwatch.com/2023/03/21/nearly-20-hindawi-journals-delisted-… Participants needed for a Motor Function Study, "Development of a Diagnostic System for Assessment of Motor Impairment," IRB# IRB-2022-1299. See below for details. Resources and further information BME PhD Defense Announcement for Xiao Liu (E. Pienaar, advisor). Everyone is invited to attend the public presentation on Mon., May 15, beginning at 1:00 PM in MJIS 2001. Title: A Deep Understanding of Ebola Virus VLP Assembly: Ode-based Modeling Approach. Thesis Committee members: Elsje Pienaar, Nan Kong, Leopold Green, Robert Stahelin Abstract: EBOV infection remains to be a challenge to human health by its high mortality rate. There are only two antibody-based therapy approved today, and the mortality rate is still high. This can be partially due to the fact that study on EBOV is strictly limited to BSL-4 labs, which hinders our understanding of the pathogen. We also lack a systematical and quantitative view of EBOV infection. Mathematical modeling has been used to assist biological and medical studies for a long time, as it has the advantage of integrating data and providing quantitative insight to a biosystem. In our study, we build the primary ODE-based model of EBOV at subcellular level step by step. Through our computation al study, we propose that PS can directly influence the oligomerization process of VP40 filaments and the budding process of VLPs. Also, the oligomerization of VP40 filaments may also follow the nucleation-elongation process. We conduct in-silico simulation to evaluate the efficiency of fendiline in treating EBOV. We find that while in general, fendiline can decrease VLP production, there can be fendiline-induced VLP production at certain time points due to slow filament growth rate or fast VLP budding rate. Also, fendiline is relatively more effective when applied in the budding stage. Moreover, it can be extra efficient when applied with VLP budding step targeted treatment. Finally, we integrate nucleoprotein (NP) into our model. We predict that NP increase VLP production through impacting filament oligomerization and VLP budding steps. Also, dual-effect of NP on VLP production may exist, as too high NP/VP40 production ratio can inversely decrease VLP production. From the aspect of protein expression time, we find that a bit earlier NP production than VP40 production is beneficial for both IB-containing VLPs production and prevention in energy waste on empty VLPs. Overall, we have built a solid foundation towards mathematical EBOV model and demonstrated its ability in assisting experimental EBOV studies. BME Summer Seminar Series, Wed., May 17, 9:30 a.m., via Zoom. The BME Summer Seminar Series will run from May 17th - August 9th. The first week's speakers will be Ruhi Sharmin and Brendan Ball. Ruhi Sharmin (Pavlos Vlachos, advisor): Spectro-temporal Feature Generation Method for Atrial Fibrillation Detection in ECGs Abstract: This work presents a framework for extracting a novel set of features from Lead II ECGs and using these features to detect atrial fibrillation. Our method pre-processes the signal using a denoising step, identification of the QRS complexes, and beat segmentation. Subsequently, we use a series of signal processing methods including proper orthogonal decomposition (POD), the continuous wavelet transform (CWT), discrete cosine transform (DCT) and the standard cross correlation to extract a total of 48 signal features. The extracted features are classified into four groups: correlation (C), morphology (M), Discrete cosine transform (D), and entropy (E). In general, these features represent novel and robust ways to characterize and assess key aspects of arrhythmias, such as beat-to-beat variability and the presence of fibrillatory waves. Subsequently, we use the feature set to train a machine learning based ECG classifier using XGBoost (eXtreme Gradient Boosting). For designing, training, and testing of our method, we used the 2017 PhysioNet Challenge dataset which annotates ECGs into categories of 'Normal', 'Atrial Fibrillation', 'Other', and 'Noisy'. For this purpose, first, we took an exhaustive grid search approach for hyper-parameter optimization of the classifier algorithm. Second, a k-fold cross-validation was used for creating k-unique subsets from the original undivided dataset for enhanced generalization of our model. Third, we partitioned each subset into different 80-20 train-test splits for building the model. The drop in the weighted average of the F1 scores of our proposed model from the training to the testing phase was only 3% whereas it was ~10% for prior works. This proves that our model is free from overfit and more generalized towards ECG dataset. On the other hand, mean F1-scores on the test dataset were 84% and 94% for the Normal and AFib categories, respectively. Moreover, the F1-score of AFib at 94% showed significant improvement (~10%) over established methods (82%~85%), while also using significantly fewer total features comparably. This demonstrates that our novel feature XGBoost arrythmia classifier can differentiate AFib and normal sinus rhythm from other arrhythmias in Lead II ECGs effectively. Moreover, by using a smaller feature set, our method is adaptable for real-time arrhythmia detection and is effective even for short (<10 beat) ECGs. Evaluation link Ruhi Sharmin: https://purdue.ca1.qualtrics.com/jfe/form/SV_eIZzuVuHE8dCC2i Brendan Ball (Doug Brubaker, advisor) ; Profiling Neuron Cytokine Expression Stimulated from Metabolites Associated with Alzheimer's Disease & Type 2 Diabetes Abstract: Alzheimer's disease (AD) is the most common form of dementia that leads to memory loss, behavioral changes, and decline of cognitive function. In the United States, more than six million people are living with AD. Of this population, 81% of people with AD also reported to have impaired glucose levels or type 2 diabetes (T2D), a metabolic disease that affects blood sugar regulation. While there is a connection between T2D and AD, the biological pathway and mechanism in which T2D exacerbates AD progression is not well-understood. A literature review revealed nine candidate metabolites that are upregulated in the presence of people with T2D, AD, or both. We compared metabolites associated with neuroprotective or neurodegenerative properties, which include lauric acid, asparagine, fructose, arachidonic acid, aminoadipic acid, sorbitol, retinol, tryptophan, and niacinamide. The nine metabolites associated with the potential development of AD or T2D were used to individually stimulate cultures of primary neurons collected from embryonic CD1 mice. After neuronal stimulation, the cell media was sampled and analyzed using a Luminex assay. Our findings indicate that cytokines involved in the JAK/STAT and chemokine receptor pathways may be involved in T2D or AD development. Specifically, we have found that cytokines including MCP-1, MIP-1alpha, and RANTES are consistently active across all metabolite stimulations, despite associations to different disease groups. These cytokines may serve an important role in AD and T2D progression. Improving our understanding of the relationship between AD and T2D will enable further studies that utilize biosystems for the development of potential treatments. Evaluation link Brendan Ball: https://purdue.ca1.qualtrics.com/jfe/form/SV_doH4Ktq6v86aBZs *Join Zoom Meeting https://purdue-edu.zoom.us/j/98811885943?pwd=Nll1MlE3TTYyOHZJL3hIYlpGSXhUUT… Meeting ID: 988 1188 5943, Passcode: biomedical BME PhD Preliminary Exam Announcement for Shulan Xiao (K. Jayant, advisor), Fri., May 19. Everyone is invited to attend the presentation beginning at 11:00 a.m. in MJIS 2001 and via Zoom. Title: The Biophysical Basis of Sensory Feature Binding in Cortical Pyramidal Neurons. Advisory committee: Krishna Jayant, Chair; Alexander A. Chubykin; Edward L. Bartlett; Fang Huang; Scott R. Pluta Abstract: Feature binding is critical for sensory perception and pattern classification. In cortical layer 2/3 and layer 5 pyramidal neurons (L2/3 and L5 PNs) feedforward inputs synapse onto basal dendritic arbors in distinct spatio-temporal patterns. How these distributed inputs integrate, multiplex, and dictate unique output codes, however, remains poorly mapped. Furthermore, it remains unclear how specific input sequences learn over time to aid pattern classification and whether this plasticity and integration is shaped by top-down feedback. To address these outstanding challenges, I have designed and implemented a new microscope capable of stimulating synapses via 3D transmitter uncaging while simultaneously recording the electrical input-output transformation. Using this platform across in vitro acute slice preparations, I propose to unravel the biophysics of multibranch dendritic integration and feature classification under quiescent and in vivo like states in L5 pyramidal neurons - the primary output layer of the cortex. Here, my aims are focused on dissecting mechanisms that underlie multiplexing across basal dendrites, plasticity mechanisms that assist efficient feature classification, and the role of top-down modulation in shaping basal dendritic integration. I propose innovative methods including two-photon holographic uncaging, dynamic clamp, computational modeling, and in vivo two-photon calcium imaging to test and validate my hypotheses. Successful completion of my aims will lead to a new understanding of how dendritic nonlinearities facilitate efficient feature classification amidst noisy backgrounds in individual L5 PNs, including different subtypes. The outcome of this finding is not only poised to improve our understanding of neural signal processing but could bolster the design of future biologically inspired artificial intelligence-based neuromorphic systems. Zoom link: https://purdue-edu.zoom.us/j/9146700686 BME PhD Defense Announcement for Mrugesh Krishna Parasa (Dr. Kevin Solomon, advisor). Everyone is invited to attend the public presentation on Tues., May 23, beginning at 3:00 PM via Zoom. Title of the Thesis Research: Programmable Control of Protein Activity via Formation of Biomolecular Condensates in Bacteria. Thesis Committee members: Dr. Kevin Solomon, Dr. Tamara Kinzer-Ursem, Dr. David Thompson, Dr. Leopold Green Abstract: Biomolecular condensates or membraneless organelles are phase separated proteins and/or other biomolecules that are ubiquitous in eukaryotic cells. While these condensates may be liquid with exchange and diffusion of their components with the rest of the cell (e.g. cytoplasm), they locally concentrate their constituent biomolecules altering their interactions in normal cellular processes. Here, we exploit this phenomenon via reversible coacervate formation to control the activity of cellular proteins in E. coli. To induce liquid-liquid phase separation, we fuse proteins to elastin-like polypeptides (ELP) that reversibly aggregate in response to increases in temperature and/or changes in intracellular pH. In so doing, we sequester their fusion partners from the cytoplasm, limiting their ability to participate in cytoplasmic reactions. We have demonstrated this concept in vivo with enzymes and transcription factors for switchable control of protein activity with temperature. For example, I-SceI mediated cleavage of a host genome can be inhibited by increasing the cultivation temperature, creating a simple temperature-sensitive kill switch; accidental release will lower the culture temperature leading to cell death. Similarly, coupled transcription factors exhibit a 2-fold increase in transcription in response to temperature. More importantly, the threshold for coacervate formation and control of protein activity may be tuned through appropriate design of the ELP fusion partner. Our results introduce a simple yet effective, rapid and tunable approach to control protein activity via induction of coacervate formation that may form a powerful new tool for synthetic biology. Zoom link: https://purdue-edu.zoom.us/j/99880181010 Participants Needed for Research Study: (Aditya Shanghavi is a graduate student in Biomedical Engineering at Purdue.) I am currently working on a research project under the direction of my advisor, Dr Anne Sereno. We are inviting you to participate in a brief arm movement study. We are specifically looking for participants aged 45-85 with no history of neurological diseases who are fluent in English and have adequate hearing (with or without amplification) to process verbal instruction and adequate vision to see the computer screen. Participants should be able to perform simple upper arm motions without experiencing major pain or discomfort. We will use non-invasive motion sensors on a wristband to collect arm motion signals during normal and simulated abnormal movements (after viewing short videos) as well as an eye tracker to collect eye motion signals during a prosaccade-antisaccade task. This study's goal is to develop algorithms to detect latencies and amplitudes of movements and to quantify the sensitivity, reliability, and accuracy of the sensors and these algorithms to differentiate normal versus simulated abnormal movements. The study should take no more than 60 minutes and it will be conducted in PSYCH 3125. We will highly appreciate you taking time out of your busy schedule and will compensate you $15 for your help in our research study in addition to our heartfelt gratitude. This study is conducted in accordance with IRB # IRB-2022-1299. If you have more questions regarding this study, please contact Aditya Shanghavi at ashangha(a)purdue.edu<mailto:ashangha@purdue.edu>. New Course for Fall 2023: BME 69500 Pediatric Medical Devices (CRN 14011). Fall 2023, 3.0 credit hours Wednesdays 11:30-2:20 in MJIS 1083 (in person attendance only) Prerequisite: BME Graduate Standing Course Description: The unique medical needs of pediatric patients in the context of current and emerging clinical technologies are presented in this novel course. Anatomical, physiological, and pathophysiological underpinnings of diseases in infants and children are studied. Unique aspects of pediatric device design, regulation, and translation, including clinical studies and ethical considerations, are explored. Numerous clinical sub specialties such as cardiology, surgery, nephrology, pulmonology, and gastroenterology are examined in terms of technology adoption and remaining clinical needs. Future directions in device development and emerging trends in patient care are considered throughout. Weekly Course Topics: August 23 Pediatrics Introduction August 30 Neonatology Introduction September 6 Pediatric Device Design and Development I September 13 Pediatric Device Design and Development II September 20 Pediatric Device Regulation September 27 Pediatric Clinical Studies October 4 Pediatric Cardiology October 18 Pediatric Cardiovascular Surgery October 25 Pediatric Nephrology November 1 Pediatric Pulmonology November 8 Pediatric Wound Healing November 15 Pediatric Gastroenterology November 29 Ethical Considerations in Pediatrics December 6 Future Directions and Trends Primary Instructor: George Wodicka, MJIS 3036, wodicka(a)purdue.edu Numerous experts from the Indiana University School of Medicine Department of Pediatrics, Riley Hospital for Children, and Cook Medical, Inc. will actively participate. Attachments 2023ClimateSurveyFlyer_Emailing.pdf Summer Seminar Flyer 2023 -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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[Bmeroundtable-list] BME Summer Seminar Announcement: May 17th 9:30-10:30am EST via Zoom
by Rowen, Elizabeth Pearl 15 May '23

15 May '23

We encourage all of you to attend and support our grad students as they participate in the second milestone of their PhD. Feedback on their presentation style and content is critical to their professional development and will be of great benefit to our students. We hope to see you there! [cid:image001.jpg@01D98348.D7985930] BME Summer Seminar Series Wednesday, May 17th, 2023 9:30-10:30 AM EST Via Zoom Meeting - link below* Evaluation links: Ruhi Sharmin: https://purdue.ca1.qualtrics.com/jfe/form/SV_eIZzuVuHE8dCC2i Brendan Ball: https://purdue.ca1.qualtrics.com/jfe/form/SV_doH4Ktq6v86aBZs Spectro-temporal Feature Generation Method for Atrial Fibrillation Detection in ECGs Ruhi Sharmin (Pavlos Vlachos, advisor) [cid:image007.jpg@01D98348.EBCF5DE0] Abstract: This work presents a framework for extracting a novel set of features from Lead II ECGs and using these features to detect atrial fibrillation. Our method pre-processes the signal using a denoising step, identification of the QRS complexes, and beat segmentation. Subsequently, we use a series of signal processing methods including proper orthogonal decomposition (POD), the continuous wavelet transform (CWT), discrete cosine transform (DCT) and the standard cross correlation to extract a total of 48 signal features. The extracted features are classified into four groups: correlation (C), morphology (M), Discrete cosine transform (D), and entropy (E). In general, these features represent novel and robust ways to characterize and assess key aspects of arrhythmias, such as beat-to-beat variability and the presence of fibrillatory waves. Subsequently, we use the feature set to train a machine learning based ECG classifier using XGBoost (eXtreme Gradient Boosting). For designing, training, and testing of our method, we used the 2017 PhysioNet Challenge dataset which annotates ECGs into categories of 'Normal', 'Atrial Fibrillation', 'Other', and 'Noisy'. For this purpose, first, we took an exhaustive grid search approach for hyper-parameter optimization of the classifier algorithm. Second, a k-fold cross-validation was used for creating k-unique subsets from the original undivided dataset for enhanced generalization of our model. Third, we partitioned each subset into different 80-20 train-test splits for building the model. The drop in the weighted average of the F1 scores of our proposed model from the training to the testing phase was only 3% whereas it was ~10% for prior works. This proves that our model is free from overfit and more generalized towards ECG dataset. On the other hand, mean F1-scores on the test dataset were 84% and 94% for the Normal and AFib categories, respectively. Moreover, the F1-score of AFib at 94% showed significant improvement (~10%) over established methods (82%~85%), while also using significantly fewer total features comparably. This demonstrates that our novel feature XGBoost arrythmia classifier can differentiate AFib and normal sinus rhythm from other arrhythmias in Lead II ECGs effectively. Moreover, by using a smaller feature set, our method is adaptable for real-time arrhythmia detection and is effective even for short (<10 beat) ECGs. Profiling Neuron Cytokine Expression Stimulated from Metabolites Associated with Alzheimer's Disease & Type 2 Diabetes Brendan Ball (Doug Brubaker, advisor) [cid:image008.jpg@01D98348.EBCF5DE0] Abstract: Alzheimer's disease (AD) is the most common form of dementia that leads to memory loss, behavioral changes, and decline of cognitive function. In the United States, more than six million people are living with AD. Of this population, 81% of people with AD also reported to have impaired glucose levels or type 2 diabetes (T2D), a metabolic disease that affects blood sugar regulation. While there is a connection between T2D and AD, the biological pathway and mechanism in which T2D exacerbates AD progression is not well-understood. A literature review revealed nine candidate metabolites that are upregulated in the presence of people with T2D, AD, or both. We compared metabolites associated with neuroprotective or neurodegenerative properties, which include lauric acid, asparagine, fructose, arachidonic acid, aminoadipic acid, sorbitol, retinol, tryptophan, and niacinamide. The nine metabolites associated with the potential development of AD or T2D were used to individually stimulate cultures of primary neurons collected from embryonic CD1 mice. After neuronal stimulation, the cell media was sampled and analyzed using a Luminex assay. Our findings indicate that cytokines involved in the JAK/STAT and chemokine receptor pathways may be involved in T2D or AD development. Specifically, we have found that cytokines including MCP-1, MIP-1alpha, and RANTES are consistently active across all metabolite stimulations, despite associations to different disease groups. These cytokines may serve an important role in AD and T2D progression. Improving our understanding of the relationship between AD and T2D will enable further studies that utilize biosystems for the development of potential treatments. *Join Zoom Meeting https://purdue-edu.zoom.us/j/98811885943?pwd=Nll1MlE3TTYyOHZJL3hIYlpGSXhUUT… Meeting ID: 988 1188 5943 Passcode: biomedical Liz Rowen She/Her Graduate Program Assistant Weldon School of Biomedical Engineering Martin C. Jischke Hall of Biomedical Engineering 206 S. Martin Jischke Drive West Lafayette, IN 47907-2032 o: 765-494-1197 [7054E290]<https://www.purdue.edu/?utm_source=signature&utm_medium=email&utm_campaign=…> -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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REMINDER: Trailblazers in Engineering Workshop for Future Faculty
by Gelfand, Johanna K 12 May '23

12 May '23

Thurs., May 25: Application Deadline for Trailblazers in Engineering workshop, to be held on the Purdue campus July 25-26. Trailblazers in Engineering (TBE) is a multi-day workshop focused on preparing future outstanding engineering scholars for future engineering faculty careers who are also committed to increase the success of underrepresented communities of engineers. Trailblazers in Engineering Fellows are selected not only for their outstanding scholarly achievements but also for their potential impact in expanding representation and diversity in engineering. See attached flyer for application instructions. [https://mailimages.purdue.edu/spacer.gif]<https://maillinks.purdue.edu/t/44460870/1434209049/83756413/0/120588/?72f79…> View as a Web page<https://maillinks.purdue.edu/t/44460870/1434209049/95083981/0/120588/?b44ed…> [Purdue and Engineering Co-brand] [Trailblazers in Engineering] JULY 24-27, 2023 Want to be a Professor in Engineering? View our Trailblazers in Engineering Promotional Video<https://maillinks.purdue.edu/t/44460870/1434209049/87609826/1/120588/?f5d63…> Apply to Trailblazers in Engineering<https://maillinks.purdue.edu/t/44460870/1434209049/95055587/1/120588/?f5d63…> Trailblazers in Engineering (TBE) is a multi-day workshop focused on preparing future outstanding engineering scholars for future engineering faculty careers who are also committed to increasing the success of underrepresented communities of engineers. Trailblazers in Engineering Fellows are selected not only for their outstanding scholarly achievements but also for their potential impact in expanding representation and diversity in engineering. The workshop will provide Fellows the ability to network with leading faculty in engineering, thought leaders, program managers at key federal funding agencies, Purdue Engineering heads, and of course, each other. Participants will also meet current Trailblazers and benefit from their inspiring keynote talks. TBE 2023 will be held in person on Purdue's beautiful West Lafayette, IN campus July 24 - 27, 2023. Reasons to Attend 1. Network with leading trailblazing faculty in engineering, thought leaders, program managers at key federal funding agencies, Purdue Engineering school heads, and scientists who will present keynote speeches and talks throughout the program. 2. Gain insight into what academic success will look like post-pandemic. 3. Participate in panel discussions. * Why choose an academic career? * How to apply & interview? * How to negotiate salary and start-up packages? * How to get early career research funding? 4. Meet program managers from the National Science Foundation, Office of Naval Research, Air Force Office of Scientific Research, National Institutes of Health and others; receive advice on your proposals; and participate in a poster session to pitch your research and teaching plans and get feedback from would-be employers. 5. Attend a session for early career teaching presented by recognized experts in faculty development. 6. For non-Purdue Fellows, we are reimbursing up to $800.00 per Economy flight and transportation (cab fare, shuttle, mileage, and/or parking to/from Purdue). For all Fellows, all lodging and meals will be provided during the workshop, July 24-27, as will per diem for travel days of July 24 (with a 4:00 PM (EDT) expected arrival time) & July 27 (with an 11:00 AM (EDT) departure time). Additional details will be provided. APPLICATION DEADLINE: May 22, 2023 Download our Printable Flyer<https://maillinks.purdue.edu/t/44460870/1434209049/95055425/1/120588/?f5d63…>

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BME PhD Defense Announcement for Mrugesh Krishna Parasa (Dr. Kevin Solomon, advisor)
by May, Sandra M 12 May '23

12 May '23

BME PhD Defense Announcement for Mrugesh Krishna Parasa (Dr. Kevin Solomon, advisor) Everyone is invited to attend the public presentation beginning at 3:00 PM. Title of the Thesis Research: PROGRAMMABLE CONTROL OF PROTEIN ACTIVITY VIA FORMATION OF BIOMOLECULAR CONDENSATES IN BACTERIA Date: May 23, 2023 Time: 3:00 PM Place: https://purdue-edu.zoom.us/j/99880181010 Thesis Committee members: Dr. Kevin Solomon, Dr. Tamara Kinzer-Ursem, Dr. David Thompson, Dr. Leopold Green Abstract: Biomolecular condensates or membraneless organelles are phase separated proteins and/or other biomolecules that are ubiquitous in eukaryotic cells. While these condensates may be liquid with exchange and diffusion of their components with the rest of the cell (e.g. cytoplasm), they locally concentrate their constituent biomolecules altering their interactions in normal cellular processes. Here, we exploit this phenomenon via reversible coacervate formation to control the activity of cellular proteins in E. coli. To induce liquid-liquid phase separation, we fuse proteins to elastin-like polypeptides (ELP) that reversibly aggregate in response to increases in temperature and/or changes in intracellular pH. In so doing, we sequester their fusion partners from the cytoplasm, limiting their ability to participate in cytoplasmic reactions. We have demonstrated this concept in vivo with enzymes and transcription factors for switchable control of protein activity with temperature. For example, I-SceI mediated cleavage of a host genome can be inhibited by increasing the cultivation temperature, creating a simple temperature-sensitive kill switch; accidental release will lower the culture temperature leading to cell death. Similarly, coupled transcription factors exhibit a 2-fold increase in transcription in response to temperature. More importantly, the threshold for coacervate formation and control of protein activity may be tuned through appropriate design of the ELP fusion partner. Our results introduce a simple yet effective, rapid and tunable approach to control protein activity via induction of coacervate formation that may form a powerful new tool for synthetic biology.

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NIH F31, F99 and F32, K99/R00 Fellowship Info sessions 5.17 and 5.18
by Siemers, Tammy R 11 May '23

11 May '23

From: Nielsen, Lisa R <lnielse(a)purdue.edu> Sent: Thursday, May 11, 2023 12:23 PM To: Nielsen, Lisa R <lnielse(a)purdue.edu> Subject: NIH F31, F99 and F32, K99/R00 Fellowship Info sessions 5.17 and 5.18 Please share the following information with your PhD students -- NIH F31, F99 Graduate Fellowship Info Session Wednesday, May 17, 4:00 - 5:00 pm ET, Online or in-person at YONG B83 Registration: https://gspd.gosignmeup.com/public/Course/browse?courseid=4087 The NIH F31 fellowships are awarded to graduate students in the first few years of a PhD program who wish to become research scientists. This webinar session will provide a writing strategy for research plans as well as advise about preparing the other required documentation. Note: US citizenship or permanent residency is required for applicants to the F31 award, but international PhD students may apply for the F99, which is a similar award. NIH F32, K99/R00 Postdoc Fellowship Info Session Thursday, May 18, 4:00 - 5:00 pm, Online or in-person at YONG B83 Registration: https://gspd.gosignmeup.com/public/Course/browse?courseid=4088 Both experienced graduate students and postdocs in the life sciences, medical sciences, and related subjects are encouraged to attend. This webinar session will provide a writing strategy for research plans as well as advise about preparing the other required documentation. The F32 fellowship and the career-focused K-awards, such as the K99, will be covered. The K99/R00 does not require US citizenship. --> Students and postdocs are encouraged to reach out to me with their questions. Kindest regards, Lisa Lisa R. Nielsen, PhD She/Her/Hers Grant Writer and Postdoc Director The Graduate School Purdue University

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[Bmeroundtable-list] MJIS ALERT
by Gelfand, Johanna K 11 May '23

11 May '23

D.A. Dodd will be in the building today and tomorrow to work on the air handling system. Air flow WILL be fluctuating over the next two days. You should be able to use the hoods in the labs, but be aware that there will be variations in air pressure and room temperatures. Sorry for the short notice. The parts came in sooner than expected, and they were willing to get this done for us in a very timely manner. Any questions or concerns, please contact Susan Hardy (hardy13(a)purdue.edu) -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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Weldon Graduate Program Announcements May 10, 2023
by Siemers, Tammy R 10 May '23

10 May '23

[4,354 Breaking News Photos and Premium High Res Pictures - Getty Images] Weldon Graduate Program Announcements May 10, 2023 * Career and Internship Opportunities * Graduate Professional Development Newsletter (May 5) * Office of Professional Development 2023 Summer Workshop Calendar * Workshops and Deadlines * News from You Career and Internship Opportunities Internship Positions * R&D Engineering Co-op 1, Fresenius Medical Care<https://jobs.fmcna.com/job/-/-/488/48434699264?src=JB-10071> * ECMO R&D Engineering Co-op, Abiomed<https://careers.abiomed.com/job/Halethorpe-ECMO-R&D-Engineering-Co-op-Mary-…> * R&D Engineering Co-op, Olympus<https://careers.olympusamerica.com/job/Westborough-R&D-Engineering-Co-Op-%2…> * Biomedical Engineer Intern, WuXi AppTec<https://www.linkedin.com/jobs/view/3600330250/?trackingId=dcJqxc8SsUWPV2%2B…> Postdoctoral Positions * NPA Website: https://careers.nationalpostdoc.org/jobs/ Full Time Positions * CQV Engineer, Azzur Group<https://www.linkedin.com/jobs/view/3475434267/?refId=fT1itWoQQXyK0beIuQ213Q…> * Scientist II, Process Development, Thermo Fisher<https://jobs.thermofisher.com/global/en/job/R-01177153/Scientist-II-Process…> * Full Time Lecturer, Center for Statistics and Machine Learning, Princeton University<https://puwebp.princeton.edu/AcadHire/apply/application.xhtml?listingId=301…> * Clinical Engineer, The University of Vermont<https://www.uvmjobs.com/postings/63064?utm_source=Indeed&utm_medium=organic…> * Manufacturing Engineer II, Boston Scientific<https://jobs.bostonscientific.com/job/Maple-Grove-Manufacturing-Engineer-II…> * Project Engineer, Pharmaceutical Focus, Jenike & Johnson<https://jenike.com/about-us/career-opportunities/project-engineer-pharmaceu…> * Biomedical Engineer, BCVS Group, Inc.<https://www.simplyhired.com/job/QEH6EWdlVGRsgMqg3Okb_DL2k2bWPwKXHFukXdgWniB…> * Associate Scientist, BMS<https://www.simplyhired.com/job/8R8QYlUloZCPVnDc_lVHti1lzwddbayqemhUxNLSWkx…> * Engineer, Product Life Cycle, LeMaitre<https://careers-lemaitre.icims.com/jobs/1925/engineer%2c-product-life-cycle…> * Senior Biomedical Engineer, Mount Sinai<https://careers.mountsinai.org/jobs/2845178?lang=en-us&src=JB-10100> * Scientist I, Downstream Process Development, Salubris Biotherapeutics<https://www.simplyhired.com/job/dZyQdDf3DwedJVimsEGZLfAvZgNYsNbyzSTjCF5u-fS…> * Scientist I, Computational Biology, Life Edit Therapeutics<https://boards.greenhouse.io/lifeedittherapeutics/jobs/4818951004> * Research Engineer, Biomedical Engineering, Atrium Health<https://emis.fa.us2.oraclecloud.com/hcmUI/CandidateExperience/en/sites/CX_1…> * Manufacturing Engineer II, Vertos Medical<https://www.vertosmed.com/careers/?gnk=job&gni=8a7887a8879c58d40187fcf1c988…> * Test Engineer, Capgemini<https://capgemini.taleo.net/careersection/1/jobdetail.ftl?job=072096&tz=GMT…> * Product Development Engineer, Katalyst Healthcares & Life Sciences<https://www.simplyhired.com/job/vZHj3enosfLp8nfgsRJ4X75NM87Re6prCm7i-ZIMNHs…> * Engineer, Sr. Quality, Boston Scientific<https://jobs.bostonscientific.com/job/Marlborough-Engineer%2C-Sr-Quality-MA…> * Purdue Start-up Job Board<https://purduefoundry.com/jobs?utm_source=Foundry+Mailing+List&utm_campaign…>-Foundry Start Up Companies Looking to Hire * ACTS Career Center<https://careers.actscience.org/>-Association for Clinical and Translational Science * Academic Careers<https://academiccareers.com/> * Doc Jobs<https://www.docjobs.com/jobs/list/>-Jobs beyond traditional clinical and academic roles Graduate Professional Development Newsletter (May 5) Graduate Professional Development Newsletter (May 5)<https://mailimages.purdue.edu/vo/?FileID=a3d06aca-8ee5-4372-8880-9a4082112c…> Office of Professional Development 2023 Summer Workshop Calendar See attached The Graduate School's Office of Professional Development has new workshops lined up for the Summer 2023 semester. Just a reminder - these workshops are free to attend for all graduate students and postdocs, and many are online. Check out the attached calendar for a list of our currently scheduled summer workshops. The calendar is linked, so if you see something you are interested in, you just need to click the date next to the workshop to access the registration page. Please note: You must have a GoSignMeUp account to register for these free workshops. Step-by-step instructions for creating an account are attached. If you have any questions, please email profdev(a)purdue.edu<mailto:profdev@purdue.edu>. Also, don't forget that the graduate student who attends the most workshops this semester will receive a $250 travel grant<https://www.purdue.edu/gradschool/professional-development/workshops/travel…>! Workshops and Deadlines Here are some upcoming workshops and deadlines more detailed information about the workshops will be sent out separately closer to the event. May 8th-10th NIH Career Symposium (Register Here<https://whova.com/portal/registration/nihca_202305/>) May 10th NSF Fellowship Workshop - Getting Started (Register Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4084>) May 11th 2023 BME GSA Graduate Research Symposium May 12th Deadline to apply for Lake Conference: Neural Coding & Dynamics (Apply Here<https://alleninstitute.org/events/lake-conferences-neural-coding-and-dynami…>) May 12th Postdoc Orientation (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4019>) May 15th Conducting a Literature Review (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4127>) May 16th Converting Your CV to a Resume (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4095>) May 16th Fellowship Office Hour for Grad Students and Postdocs (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4085>) May 16th-18th Next-Generation Transport Systems (NGTS) Conference (Register Here<https://purdue.ca1.qualtrics.com/jfe/form/SV_5yXj6WohpRieXeC>) May 17th NSF Fellowship Workshop - Personal Statement (Register Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4086>) May 17th The Cover Letter (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4096>) May 17th NIH Fellowship F31 Info Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4087>) May 18th Postdoc Houston - Virtual Info Session for Prospective Postdocs (Register<https://www.postdochouston.org/>) May 18th Business Meal Etiquette (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4128>) May 18th NIH F32 and K99/R00 Info Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4088>) May 22nd Deadline to apply for Trailblazers in Engineering (TBE) Workshop (Apply Here<https://engineering.purdue.edu/Engr/Trailblazers/?utm_source=delivra&utm_me…>) May 22nd Boiler Up & Intervene Workshop (CARE<https://gspd.gosignmeup.com/public/Course/browse?courseid=4094>) May 22nd Preparing a Teaching Demonstration (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4147>) May 22nd Debt Management (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4135>) May 23rd Preparing for Academic Interviews (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4149>) May 24th NSF Fellowship Workshop - Research Statement (Register Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4090>) May 24th USDA AFRI Fellowship Info Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4089>) May 24th Preparing to Buy a House (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4137>) May 24th GRIP workshop: Citation Management with Zotero (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4133>) May 24th-25th Facilitating Entering Mentoring Workshop (CIMER<https://sites.google.com/wisc.edu/facilitatingenteringmentoring/home?pli=1>) May 25th Eating Right When Your Budget is Tight (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4143>) May 25th NSF Fellowship Help Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4097>) May 26th Credit Cards and Credit Scores (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4139>) May 31st How to Find and Prepare for Fellowship Applications (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4102>) May 31st NSF Fellowship Help Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4099>) June 5th Publishing a Scientific Paper (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4091>) June 6th CARE-ing Support: Responding to Disclosures of Interpersonal Violence (CARE<https://gspd.gosignmeup.com/public/Course/browse?courseid=4100>) June 6th NDSEG (Defense Research) Fellowship Info Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4125>) June 6th Budgeting and Saving Money (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4141>) June 14th RCR: Discipline-Specific Training (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4130>) June 14th NSF Fellowships - Getting Started (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4103>) June 14th GRIP workshop: Citation Management with Zotero (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4134>) June 15th Business Meal Etiquette (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4129>) June 15th Postdoc Grant Writing: Logic Flow and Methods (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4106>) June 15th NSF Fellowship Help Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4105>) June 19th Debt Management (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4136>) June 20th Fellowship Office Hour for Grad Students and Postdocs (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4107>) June 21st NSF Fellowships - Personal Statement (Grantsmanship) (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4104>) June 22nd Mentorship Training for Postdocs: Communication Between Mentors & Mentees (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4110>) June 22nd NSF Fellowship Help Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4108>) June 27th Preparing to Buy a House (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4138>) June 28th NSF Fellowship Workshop - Research Statement (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4111>) June 28th Credit Cards and Credit Scores (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4140>) June 29th NSF Fellowship Help Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4109>) July 6th NSF Fellowship Help Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4116>) July 7th Power & Control Workshop (CARE<https://gspd.gosignmeup.com/public/Course/browse?courseid=4101>) July 7th Postdoc Orientation (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4112>) July 14th RCR: Discipline-Specific Training (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4131>) July 18th Publishing a Scientific Paper (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4092>) July 18th NSF Fellowship Life Sciences Panel (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4113>) July 18th NSF Fellowship Physical and Computational Sciences Panel (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4118>) July 18th Fellowship Office Hour for Grad Students and Postdocs (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4117>) July 19th NSF Fellowship Engineering Panel (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4119>) July 19th NSF Fellowship Social Sciences and Education Panel (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4114>) July 20th NSF Fellowship Agriculture Panel (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4115>) July 20th Business Meal Etiquette (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4145>) July 20th NSF Fellowship Help Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4120>) July 24th Budgeting and Saving Money (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4142>) July 25th Computational Fellowships Info Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4126>) July 26th How to Find and Prepare for Fellowship Applications (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4121>) July 26th NDSEG (Defense Research) Fellowship Info Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4124>) July 27th Postdoc Grant Writing: All About NSF (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4123>) July 27th NSF Fellowship Help Session (Enroll Here<https://gspd.gosignmeup.com/public/Course/browse?courseid=4122>) July 24th-25th Facilitating Entering Mentoring Workshop (CIMER<https://sites.google.com/wisc.edu/facilitatingenteringmentoring/home?pli=1>) News from You Please inform Tammy of honors, awards, or other accolades (to include having a paper published) you receive so that the Weldon School may recognize your accomplishments. Send the complete information - specific title and nature of the award, name of conference or event at which award was given, date of said event, photograph if available, etc. - to tsiemers(a)purdue.edu<mailto:tsiemers@purdue.edu>. Tammy Siemers She/Her Associate Director, Graduate Education Weldon School of Biomedical Engineering 206 S. Martin Jischke Drive, West Lafayette, IN 47907-2032 o: 765-496-0294 Achiever, Relator, Includer, Restorative, Developer [233FFCD4]<https://www.purdue.edu/?utm_source=signature&utm_medium=email&utm_campaign=…>

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