November 2025 - Bmegradstudents-list

ME Seminar featuring Jessica Zhang, CMU
by Rhonda Wolf Jones 18 Nov '25

18 Nov '25

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[Bmeroundtable-list] FW: Please share: Invitation to CALC Colloquium, Nov. 21, Joseph Wallace
by Rhonda Wolf Jones 17 Nov '25

17 Nov '25

[cid:image001.png@01DBA4A7.BF6BFA60] Please join us for the next CALC Colloquium Friday, November 21, where Joseph Wallace, PhD, will present on "Targeting Tissue Quality as an Interventional Approach to Improve Bone Fracture Resistance." Dr. Wallace is a Professor in the Weldon School of Biomedical Engineering (BME) and serves as Associate Vice President for Research Development, overseeing the short-term portfolio and long-term vision for research for the Indianapolis expansion of Purdue University. His research program centers on musculoskeletal tissues, with a focus on bone mechanics (ability to bear loads) and mechanobiology (how cells respond to mechanical stimulus to maintain or increase bone mass). You may click on the image below to RSVP (and choose in-person or virtual attendance on the second screen). Registration will close Wednesday, November 19. [cid:image002.png@01DC48D8.37D9AAE0]<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca…> We hope to see you there! Paige Ebner Assistant Director Center on Aging and the Life Course Purdue University 501 Northwestern Avenue MSEE 308C West Lafayette, IN 47907 765-494-9692 mebner(a)purdue.edu<mailto:mebner@purdue.edu> www.purdue.edu/aging<http://www.purdue.edu/aging> Aging Exchange-CALC Newsletter Fall 2025<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fonline.fl…> [cid:image003.png@01DC48D8.37D9AAE0]<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.faceb…>[cid:image004.png@01DC48D8.37D9AAE0]<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.insta…>[cid:image005.png@01DC48D8.37D9AAE0]<https://nam04.safelinks.protection.outlook.com/?url=http%3A%2F%2Flinkedin.c…> -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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FW: Request to share: RCAC RNA-seq hands-on workshop anouncement
by Kevin John Otto 17 Nov '25

17 Nov '25

From: Arun S Seetharam <aseethar(a)purdue.edu> Sent: Monday, November 17, 2025 10:52 AM To: BME Head <BMEHead(a)groups.purdue.edu> Subject: Request to share: RCAC RNA-seq hands-on workshop anouncement Dear Dr. Otto, I'm writing to ask for your help in sharing an upcoming hands-on RNA-seq workshop with researchers in your department who work with genomic or transcriptomic data. If your faculty, postdocs, or graduate students use RNA-seq in their research, I would appreciate you passing this invitation along. Thank you in advance for your help. Announcement: RNA-seq in practice: A one-day hands-on workshop on RCAC systems This in-person workshop provides a practical introduction to running RNA-seq analyses on Purdue's high-performance computing (HPC) systems. Participants will work through the complete workflow, from quality control through differential expression, with an emphasis on reproducibility and cluster-based execution. Basic command-line familiarity is recommended, but no prior experience with RNA-seq analysis is required. Date: Thursday, November 20, 2025 Time: 9:00 AM - 4:00 PM (ET) Location: SC 179 Details & Registration: https://www.rcac.purdue.edu/news/7441 Thank you again for helping us share this with your department. Thanks, Arun Seetharam, PhD (he/him) Lead Bioinformatics Scientist aseethar(a)purdue.edu<mailto:aseethar@purdue.edu>

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[Bmeroundtable-list] Seminar Speaker, Wed. Nov 19
by Rhonda Wolf Jones 17 Nov '25

17 Nov '25

[cid:image001.jpg@01DC57A1.608803B0] -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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[Bmeroundtable-list] FW: You're invited! Bench to Bedside: An Interdisciplinary Approach to Understanding Rheumatoid Arthritis and Bone Fractures
by Rhonda Wolf Jones 17 Nov '25

17 Nov '25

You are invited to attend our Grand Round Series. These sessions are part of a collaborative initiative between Indiana University Health and Purdue University aimed at fostering cross-institutional dialogue. Our goal is to connect Purdue researchers with real-world clinical challenges and introduce IU Health clinicians to cutting-edge research and innovative technologies. You can also find this information on the Office of Research Events webpage<https://www.purdue.edu/research/oevprp/events/>. Bench to Bedside: An Interdisciplinary Approach to Understanding Bone Fractures Monday, November 24, 2025 10:00-11:00 AM EST Drug Discovery Lobby Conference Room IU Speaker: Dr. Roman M. Natoli, MD, PhD Purdue Host: Dr. Phil Low, PhD [GR_Flyer_Vaugn_Natoli_Purdue.png] We encourage all who are interested to join us for this engaging and interdisciplinary discussion. -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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[Bmeroundtable-list] Help Stock Our Pantry: Food Drive for Students in Need
by Rhonda Wolf Jones 17 Nov '25

17 Nov '25

Dear Weldon Faculty, Staff and Students, We're coming together to support members of our own community who could use a helping hand. Some of our students are facing food insecurity, and we're launching a Food Drive to help stock a small on-site pantry to provide them with reliable access to meals and snacks. We invite you to contribute nonperishable food items such as: * Canned soups, fruits and vegetables * Peanut butter, pasta, rice and cereal * Granola bars, snacks and other shelf-stable items Donations can be dropped off at the white boxes in MJIS or SL220 between now and the end of the semester. Every contribution-large or small-makes a real difference. Together, we can make sure no one in our community goes hungry. Thank you for your kindness and generosity! Boiler Up! Rhonda Jones (she/her/hers) Senior Marketing and Communications Professional Weldon School of Biomedical Engineering O 765.494.3940 | C 765.427.2065 rwjones(a)purdue.edu [cid:image001.png@01DC579E.EAB5BB20] -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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[Bmeroundtable-list] BME Master’s Defense Announcement for Youssef Beshay (M. Ward, advisor)
by Sandra M May 14 Nov '25

14 Nov '25

BME Master’s Defense Announcement for Youssef Beshay (M. Ward, advisor) Everyone is invited to attend the public presentation beginning at 1:00 PM. Title: Bespoke Computational Tools for Gastrointestinal Medicine Date: Wednesday, November 19, 2025 Time: 1:00 PM Location: DLR 131 and Zoom [invitation below] Committee: Dr. Matthew Ward (Chair), Dr. Kevin Otto, Dr. Ken Yoshida Abstract: The gastrointestinal (GI) tract is a network of organs that food passes through, with mechanical impairments and neurological compromises impacting one's quality of life significantly. Here, I present two distinct works, promoting interdisciplinary research in the GI scope. The first chapter involves understanding the mechanical characteristics of the esophagus in eosinophilic esophagitis (EoE), an inflammatory condition leading to fibrotic remodeling and diffuse esophageal stiffening. I present a MATLAB-based graphical user interface (GUI) that processes raw data from a functional luminal imaging probe (FLIP) to capture esophageal peristaltic motion in the presence of a distending balloon and help identify mechanically impaired regions. With implications extending to many conditions impacting the luminal structures of the GI tract, the information presented may contribute towards personalized dilation treatments. In the second chapter, I select gastroparesis, a neurogastroenterological condition characterized by delayed gastric emptying, as a model disease in which vagal nerve stimulation (VNS) may be used to manage symptoms like nausea and vomiting. Currently, our knowledge of the function of vagal fibers is limited, and the adopted VNS paradigm is open-loop and stimulus-based, resulting in variable treatment outcomes among patients. Contributing towards the development of autonomous, closed-loop VNS control, we offer heuristic models (HAPI) of extracellular, differential recordings of single fiber action potentials (SFAPs) and compound action potentials (CNAPs) for myelinated and unmyelinated fibers to supplement CNAP-guided bioelectronic therapy. Providing an accessible wealth of explainable information to the broader neuroscience community, HAPI may help engage diameter-specific groups of fibers in the vagal nerve. Zoom Invitation Youssef Beshay is inviting you to a scheduled Zoom meeting. Topic: Youssef Beshay – M.S. Thesis Defense Time: Nov 19, 2025 01:00 PM America/Indiana/Indianapolis Join Zoom Meeting https://purdue-edu.zoom.us/j/93338964785?pwd=nV53jDzgbIhkPY97aLQg9Z8b4fXWzY…<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-ed…> Meeting ID: 933 3896 4785 Passcode: 513352 One tap mobile +13052241968,,93338964785#,,,,*513352# US +13092053325,,93338964785#,,,,*513352# US Join by SIP • 93338964785(a)zoomcrc.com Passcode: 513352 Join instructions https://purdue-edu.zoom.us/meetings/93338964785/invitations?signature=zch0Y…<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-ed…> -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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[Bmeroundtable-list] BME Master’s Defense Announcement for Margaret E. Love (F. Huang and T. Ratliff, co-advisors)
by Sandra M May 14 Nov '25

14 Nov '25

BME Master’s Defense Announcement for Margaret E. Love (F. Huang and T. Ratliff, co-advisors) Everyone is invited the attend the public presentation beginning at 3:00 PM. Title: Linking Folate Receptor Beta Expression to Sex Differences and Metabolic Reprogramming in Tumor Associated Macrophages Date: Tuesday, December 2, 2025 Time: 3:00 PM Location: MJIS 2001 Committee: Dr. Fang Huang/Dr. Timothy Ratliff (co-advisors), Dr. Tamara Kinzer-Ursem Abstract: As tumors progress, their microenvironment is reshaped to support tumor growth, including the repolarization of tumor associated macrophages (TAMs) from tumor-killing to tumor-promoting states. One marker that identifies an immunosuppressive subset of TAMs, the folate receptor beta (FRβ), has become a promising target for immunotherapeutics because its expression correlates with poor overall survival and treatment resistance. The mechanisms governing upregulation of FRβ and its contribution to immunosuppressive activity remain poorly understood. In collaboration with Dr. Phillip Low’s group, we are testing a folate-conjugated TLR7 agonist (FA-TLR7a) designed to target FRβ⁺ TAMs and repolarize them toward an M1 phenotype. Treatment responses differ between males and females, motivating us to investigate sex-based differences in FRβ expression. We developed a FRβ-mCherry knock-in mouse model that allows for simple fluorescent identification of FRβ+ cells. Using dSTORM imaging, we observed higher FRβ expression in female monocytes, suggesting an explanation for these treatment disparities. To further define how FRβ contributes to macrophage function, I applied confocal and two-color expansion microscopy to visualize mitochondrial organization to study how the presence of folate metabolism (FOCM) influences mitochondrial function. Quantification of features such as network size, branch length, and footprint enabled mapping of macrophage polarization along the M1-to-M2 spectrum, where metabolism transitions from glycolysis to oxidative phosphorylation to support tumor-promoting functions. Findings indicate that FRβ expression correlates to a larger, more fused mitochondrial morphology, potentially indicating a more activated, polarized, and stabilized M2 phenotype to carry out suppressive function. I hypothesize this occurs through FOCM’s support of purine metabolism and stress response pathways, which enhance mtDNA generation and stability, reinforcing M2-like metabolism and promoting adenosine production. Bulk RNA sequencing of FRβ+ TAMs further supported this model, revealing upregulation of energy, purine metabolism, and antioxidants produced by FOCM. These analyses suggest that FOCM-driven purine metabolism and glutathione production by FOCM may increase adenosine levels and the differentiation of immunosuppressive prostaglandins. Overall, these findings point to a support system between FOCM and immunosuppressive function, but further analysis is needed to confirm the mechanisms at play. -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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[Bmeroundtable-list] EPICS is looking for a Director
by Rhonda Wolf Jones 14 Nov '25

14 Nov '25

https://careers.purdue.edu/job/AssociateFull-Professor-of-Engineering-Pract…<https://careers.purdue.edu/job/AssociateFull-Professor-of-Engineering-Pract…> Position Summary: Purdue University's College of Engineering invites applications for a non-tenure track professor of engineering practice faculty position (at the associate professor or professor rank) to lead the internationally recognized EPICS (Engineering Projects in Community Service)<https://engineering.purdue.edu/EPICS> Program. The responsibilities of the position will be split between the EPICS Program and the hiring School in the College of Engineering. EPICS is a service-learning design program in which teams of students partner with local and global community organizations to address human, community, and environmental needs. EPICS was founded at Purdue University in Fall 1995 and has been adopted at more than 40 universities and colleges. Purdue is the home of the EPICS University Consortium -a collaborative network of universities that freely share ideas and experiences to support program development. The EPICS model has also been extended to pre-college education, with over 100 middle and high schools offering EPICS courses supported by the EPICS Program. The successful candidate will serve as Director of EPICS, providing strategic leadership in developing, disseminating and supporting service-learning models that engage students in engineering and computing-based design projects that meet the needs of their communities for all three aspects of the EPICS program: the Purdue courses at the West Lafayette and Indianapolis locations, the University Consortium, and the K-12 Program. This role includes fostering innovation in engineering education, expanding partnerships with community, corporate, higher education, foundation, and philanthropic organizations, securing external funding, and promoting interdisciplinary collaboration across campus and beyond. Responsibilities associated with the hiring School of Engineering can include teaching, engagement, scholarship, and service. Boiler Up! Rhonda Jones (she/her/hers) Senior Marketing and Communications Professional Weldon School of Biomedical Engineering O 765.494.3940 | C 765.427.2065 rwjones(a)purdue.edu [cid:image001.png@01DC556C.13070B90] -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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[Bmeroundtable-list] Art in Research
by Rhonda Wolf Jones 14 Nov '25

14 Nov '25

[cid:image004.png@01DC5552.0A3D21D0] Boiler Up! Rhonda Jones (she/her/hers) Senior Marketing and Communications Professional Weldon School of Biomedical Engineering O 765.494.3940 | C 765.427.2065 rwjones(a)purdue.edu [cid:image003.png@01DC5552.0A221FC0] -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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