December 2025 - Bmegradstudents-list

[Bmeroundtable-list] Seminar Speaker, Dec. 10
by Rhonda Wolf Jones 04 Dec '25

04 Dec '25

[cid:image001.png@01DC64FC.260525C0] Wednesday, December 10, 2025 | 9:30 - 10:20am, MJIS 1001 Students registered for the seminar are expected to attend in-person. Join Zoom Meeting https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-ed…<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-ed…> Meeting ID: 974 3815 6086 --- One tap mobile +13092053325,,97438156086# US +13126266799,,97438156086# US (Chicago) --- Join by SIP * 97438156086(a)zoomcrc.com<mailto:97438156086@zoomcrc.com> "Effects of Vagal Nerve Stimulation on Stress and Addictions" [cid:image002.jpg@01DC64FC.260525C0] J. Douglas Bremner, MD Emory University Abstract: Objective: Posttraumatic Stress Disorder (PTSD) and opioid withdrawal are both associated with increased activation of the sympathetic nervous system. Transcutaneous cervical vagus nerve stimulation (tcVNS) reduces sympathetic function and inflammation and therefore has potential to help patients with PTSD or Opioid Use Disorder (OUD). Methods: Patients with PTSD and those with OUD undergoing acute opioid withdrawal were randomly assigned to receive double blind active tcVNS or sham stimulation with exposure to personalized traumatic scripts or opioid cue videos. PTSD patients underwent three months of tcVNS or sham stimulation twice daily and monthly in conjunction with a paragraph of memory encoding task. Results: tcVNS compared to sham resulted in significant reductions in sympathetic function measured with pre-ejection period (PEP) in PTSD (p<.05) and subjective opioid withdrawal (p = .047), pain (p = .045), and distress (p = .004) in OUD patients and enhanced medial prefrontal brain function in both groups. Paired tcVNS with memory encoding resulted in a 99% increase in memory recall over three months not seen with sham stimulation. Conclusions: tcVNS reduces behavioral and physiological manifestations of PTSD and opioid withdrawal and has positive effects on cognition and memory. Biography: J. Douglas Bremner, M.D., is Professor of Psychiatry and Radiology and Director of the Emory Clinical Neuroscience Research Unit at Emory University School of Medicine in Atlanta, Georgia, and Staff Psychiatrist at the Atlanta VA Medical Center. His research focuses on the neurobiology of posttraumatic stress disorder, depression, and opioid use disorder, using neuroimaging and behavioral measures to understand the effects of stress on brain and physical health. Bremner's studies using MRI to show smaller hippocampal volume in PTSD and depression are among the most cited in the field. He developed widely used behavioral measures including the Early Trauma Inventory and Clinician Administered States Scale. His work on non-invasive vagus nerve stimulation led to FDA Breakthrough Device Designation for PTSD in 2022 and continues to expand to opioid use disorder and cognitive disorders. Bremner has authored more than 400 scientific articles, edited three books, and written six books. He earned his medical degree from Duke University and completed residencies in Psychiatry and Nuclear Medicine at Yale School of Medicine, where he also served as Director of the Yale Trauma Research Program before joining Emory in 2000. ~ BME Host: Matthew Ward ~ -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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Fw: BIOL 628 Microscopy for Life Scientists Spring 2026
by Tammy R Siemers 03 Dec '25

03 Dec '25

Get Outlook for iOS<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Faka.ms%2F…> ________________________________ From: Daniel M Suter <dsuter(a)purdue.edu> Sent: Wednesday, December 3, 2025 5:48 PM To: Tammy R Siemers <tsiemers(a)purdue.edu> Subject: BIOL 628 Microscopy for Life Scientists Spring 2026 Hi Tammy, I hope you are doing well. Would it be possible to share the attached course information with the BME graduate students? This is a great course that covers all aspects of light microscopy from basic optics to digital image analysis. There is still space in the class for the spring semester in case any of the BME graduate students is interested. Thank you! Daniel Daniel Suter, PhD Professor and Associate Head Department of Biological Sciences Purdue University 915 Mitch Daniels Boulevard, Lilly 2-239 West Lafayette, IN 47907 765-496-1562 dsuter(a)purdue.edu<mailto:dsuter@purdue.edu> https://www.bio.purdue.edu/People/profile/dsuter.html http://suterlab.bio.purdue.edu/

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[Bmeroundtable-list] Let’s flood the 38⧸38 nominations with incredible BME alumni!
by Rhonda Wolf Jones 03 Dec '25

03 Dec '25

Let’s flood the 38⧸38 nominations with incredible BME alumni! The portal for the 2026 class is open, and nominating someone is super easy—all you really need is their date of birth to confirm they’ll be 38 or younger as of January 1, 2026. Don’t know it? Even better—reach out, reconnect, and let them know you’d like to nominate them. It’ll make their day! Who are we looking for? Alumni who: • Are on a fast rise—early promotions, leadership roles, significant recognitions, impactful research, or standout entrepreneurial success • Have made a meaningful impact on their organization, community, or field—whether through revenue, innovations, patents, startups, citations, or lives improved Key details • Deadline: January 31, 2026 • Nomination link: https://my.reviewr.com/s2/site/purdue-engineering-38-38-nomination<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmy.review…> Our 2025 pool was incredibly strong, with many BME nominees just shy of the top 38. One more year of achievements could put them over the edge—so please re-nominate past candidates and bring new stars into the mix! Let’s show the College what the Weldon School is made of! Boiler Up! Rhonda Jones (she/her/hers) Program Administration & Events Specialist Weldon School of Biomedical Engineering O 765.494.3940 | C 765.427.2065 rwjones(a)purdue.edu [cid:image001.png@01DC6475.2C804FB0] -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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FW: BME Events on Monday 12/8
by Rhonda Wolf Jones 02 Dec '25

02 Dec '25

BME Colleagues: I want to invite you all to two important events on Monday, December 8th. Please also help advertise these events to your students. 1. BME Student Forum - 11:00 am - 1:00 pm in SL 165 All BME students (UG & GRAD), staff, and faculty are welcome to come discuss the past, present, and future of Purdue BME in Indianapolis. ME held a similar event recently and had excellent turnout. Kevin and I will be there throughout, but it would be great to have other faculty and staff pop in when you are available. There will be pizza for all. 1. BME Capstone QuickFire Presentations - 3:30 - 5:00 pm in the Lilly Auditorium (UL 0130) Please join us to support our BME seniors in Indianapolis and to give them feedback on their ideas and progress! We will have eight teams presenting. Both events should be on your calendars. I hope to see you there! Best, Steve -- Steve Higbee, PhD Director for BME Programs in Indianapolis Associate Professor of Engineering Practice Weldon School of Biomedical Engineering Purdue University (765) 495-7695 | shigbee(a)purdue.edu<mailto:shigbee@purdue.edu> | BMEed Lab<https://engineering.purdue.edu/BMEED>

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Reminder: Seminar Speaker tomorrow
by Rhonda Wolf Jones 02 Dec '25

02 Dec '25

[cid:image001.png@01DC63AB.EF58E490] Wednesday, December 3, 2025 | 9:30 - 10:20am, MJIS 1001 Students registered for the seminar are expected to attend in-person. Teams Meeting ID: 211 123 896 292 8 Passcode: Uh9qs2pf "Complex in vitro systems to study neurovascular function in health and disease" [cid:image002.jpg@01DC63AB.EF58E490] Roger D. Kamm Cecil and Ida Green Distinguished Professor of Biological and Mechanical Engineering Massachusetts Institute of Technology Departments of Biological Engineering and Mechanical Engineering Abstract: With our aging population, neurodegenerative diseases are on the rise, far out pacing increases in other common diseases. Recent advances from the pharmaceutical industry have produced new drugs capable of reducing the rate of decline in patients with Alzheimer's disease and many more are in the drug development pipeline. This, combined with improved understanding of the factors that influence a variety of neurodegenerative diseases has given rise to increased interest both in the delivery of drugs to the brain, and their effects to alleviate symptoms or prevent disease progression. Innovative in vitro platforms are needed to screen for new therapies and enhance delivery of biologics to the brain. Results will be presented showing one model that captures in vivo morphology and function and that can be used both to measure transport across the blood-brain barrier and the effects in disease models of new therapeutics on vascular or neural function. Biography: Kamm's research focuses on problems at the interface of biology and mechanics, formerly in cell and molecular mechanics, and now in engineered living systems. Current interests are in developing models of healthy and diseased organ function using microfluidic technologies, with a focus on vascularization, cancer and neurological disease. Kamm is a member of the National Academies of Medicine and Engineering. He is co-founder of AIM Biotech, a manufacturer of microfluidic systems for 3D culture. ~ BME Host: Tae Yoon Kim ~

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Spring Course: ME 597 Distributed Energy Resources
by Tammy R Siemers 02 Dec '25

02 Dec '25

Hi everyone, Professor Kircher requested I send this communication out to advisors/grad admins to help get the word out to both fully online and residential students about this course. Course: ME 59700 Distributed Energy Resources 3 credit hours Full term Spring 2026 course Instructor: Kevin Kircher kkirche(a)purdue.edu<mailto:kkirche@purdue.edu> Fully Online Students CRN: 41013 Residential Students CRN: 14760 * Tuesday/Thursday 9-10:15am Here is the course website from Spring 2025: https://kevinjkircher.com/distributed-energy-resources/<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fkevinjkir…> It includes the lecture slides and videos, homework assignments, readings, etc. The syllabus is attached! Thanks, Alisha Alisha Severson Associate Director of Administration for Continuing and Online Education College of Engineering and Purdue Polytechnic Institute http://www.purdue.edu/online [cid:image001.png@01DC629E.AA87E5E0]

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[Bmeroundtable-list] BME PhD Preliminary Exam Announcement for Farhan Sadik (R. Surowiec, advisor)
by Sandra M May 02 Dec '25

02 Dec '25

BME PhD Preliminary Exam Announcement for Farhan Sadik (R. Surowiec, advisor) Everyone is invited to attend the public presentation beginning at 11:00 AM. Title: Motion Correction in High-Resolution Medical Imaging: From Modality-Specific Solutions in HR-pQCT and UTE-MRI Toward Generalized Medical Image Reconstruction Date: December 15th, 2025 Time: 11:00 AM Location: MJIS 1083 Microsoft Teams Link: Farhan's Tentative Preliminary Exam | Meeting-Join | Microsoft Teams<https://teams.microsoft.com/l/meetup-join/19%3ameeting_MTQ3ODIzMDQtN2ZlMS00…> Committee Members: Dr. Rachel Surowiec (Chair), Dr. Joseph Wallace, Dr. Young Kim, Dr. Fengqing Zhu, and Dr. Uzay Emir Abstract: Despite advances in foundation-model-driven medical image segmentation, classification, and synthesis, motion remains a major bottleneck, where even minor patient movement can render scans unusable. Current solutions, such as rescanning or discarding corrupted scans, are costly and inefficient. This proposal focuses on developing an automated framework for motion correction and image restoration across imaging modalities, beginning with two specific modalities: high-resolution peripheral quantitative computed tomography (HR-pQCT) for bone imaging and ultrashort-echo time magnetic resonance imaging (UTE-MRI) for pulmonary imaging. For HR-pQCT, I construct a physics-driven motion simulation pipeline that perturbs motion-free scans according to the CT data-acquisition physics, enabling the generation of a large, diverse dataset with controllable motion artifacts. Building on this dataset, I introduce an edge-enhanced self-attention Wasserstein generative adversarial network (ESWGAN) to correct rigid motion in the simulated domain. Furthermore, to transfer the learned motion correction capability to real-world scans, I introduce a Dual-CycleGAN architecture that adversarially narrows the gap between simulated and real corrupted images, thereby enabling robust correction of motion artifacts in real-world HR-pQCT data. For non-rigid motion in free-breathing neonatal UTE-MRI, I utilize a novel petal-like rosette trajectory (PETALUTE), combined with k-space-based motion signal extraction and iterative compressed sensing to achieve motion-compensated reconstruction. Finally, I aim to explore generalized MRI/CT reconstruction under varying degradations, moving toward foundational models for inverse imaging problems. Preliminary results demonstrate state-of-the-art performance: in HR-pQCT, motion correction achieves 5.42% improvement in PSNR from the baseline, while the domain adaptation framework successfully transfers these performances to real-world scans. In neonatal pulmonary imaging, PETALUTE acquisition yields superior motion-compensated reconstruction compared to traditional radial UTE acquisition. Overall, my work addresses motion-induced image degradation, preserves valuable datasets, cuts clinical costs, and has the potential to establish a foundation for generalized medical image reconstruction. -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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[Bmeroundtable-list] BME PhD Defense Announcement for Adam Wright (Y. Tong, advisor)
by Sandra M May 02 Dec '25

02 Dec '25

BME PhD Defense Announcement for Adam Wright (Y. Tong, advisor) Everyone is invited to attend the public presentation beginning at 1:00 PM. Title: MRI Techniques to investigate cerebral neurofluid dynamics across aging and disease. Date: Tuesday December 16th, 2025 Time: 1:00 PM Location: MJIS 2001 and Zoom Meeting link: https://purdue-edu.zoom.us/j/9302687285?pwd=MUF1WDludmxQMzYwdkVUNWFWakhNQT09<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-ed…> Meeting ID: 930 268 7285 Passcode: kk1The Committee: Yunjie Tong (Chair) Qiuting Wen Igor Fernandes Vitaliy Rayz Abstract: The brain is a remarkable organ, constantly engaged in maintenance to support our everyday thoughts, actions, and experiences. Proper function depends on continuous nutrient delivery and waste clearance, which is sustained by a delicate balance of arterial blood delivery, venous return, and cerebrospinal fluid (CSF) movement. These neurofluid dynamics are tightly coupled to cardiac pulsations; however, the high frequency of the heart rate makes them difficult to capture with standard magnetic resonance imaging (MRI). This dissertation develops and validates multiple MRI techniques to capture cardiac-driven neurofluid dynamics, providing important insights into cerebral physiology despite slower imaging speeds. Although functional MRI (fMRI) is traditionally used to study neuronal activity, the techniques developed here demonstrate that it also contains rich physiological information relevant to neurofluid dynamics, that can be leveraged to: 1) quantify the coupling between vascular and perivascular fluid dynamics, 2) recover cardiac pulsations in scans where these signals would otherwise be corrupted, and 3) measure the cardiac pulse propagation from arteries to veins. These tools provide new insights into brain waste clearance mechanisms, vascular hemodynamics, and the intracranial mechanical environment. They were applied to aging populations to characterize typical age-related changes, and the waste clearance mechanisms were subsequently used in an Alzheimer's disease cohort to assess whether impaired clearance is associated with pathological waste accumulation. Collectively, these techniques provide a framework to study brain function and dysfunction in aging and neurological disease. -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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[Bmeroundtable-list] BME Beats on Wednesday and Popcorn
by Rhonda Wolf Jones 01 Dec '25

01 Dec '25

[cid:image001.jpg@01DC62C0.4E8DC8F0] Boiler Up! Rhonda Jones (she/her/hers) Program Administration & Events Specialist Weldon School of Biomedical Engineering O 765.494.3940 | C 765.427.2065 rwjones(a)purdue.edu [cid:image002.png@01DC62C0.4E8DC8F0] -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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[Bmeroundtable-list] REMINDER: Help Stock Our Pantry: Food Drive for Students in Need
by Rhonda Wolf Jones 01 Dec '25

01 Dec '25

Dear Weldon Faculty, Staff and Students, We're coming together to support members of our own community who could use a helping hand. Some of our students are facing food insecurity, and we're launching a Food Drive to help stock a small on-site pantry to provide them with reliable access to meals and snacks. We invite you to contribute nonperishable food items such as: * Canned soups, fruits and vegetables * Peanut butter, pasta, rice and cereal * Granola bars, snacks and other shelf-stable items Donations can be dropped off at the white boxes in MJIS or SL220 between now and the end of the semester. Every contribution-large or small-makes a real difference. Together, we can make sure no one in our community goes hungry. Thank you for your kindness and generosity! Boiler Up! Rhonda Jones (she/her/hers) Senior Marketing and Communications Professional Weldon School of Biomedical Engineering O 765.494.3940 | C 765.427.2065 rwjones(a)purdue.edu<mailto:rwjones@purdue.edu> [cid:image001.png@01DC579E.EAB5BB20] -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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