July 2023 - Bmegradstudents-list

[Bmeroundtable-list] BME Weekly Roundtable - July 18, 2023
by Gelfand, Johanna K 18 Jul '23

18 Jul '23

[cid:image001.jpg@01D9B979.D02976E0] BME WEEKLY ROUNDTABLE July 17, 2023 INTERIM HEAD'S NOTE * Vitaliy Rayz and I are pleased to announce Elsje Pienaar, Assistant Professor of Biomedical Engineering, will assume the role of Director of Undergraduate Programs and Chair of the Undergraduate Curriculum Committee in the Weldon School. Please join us in welcoming Elsje into her new role, as she leads our undergraduate programs to new levels of excellence. * The Trailblazers in Engineering workshop will take place next week. There will be a couple of keynote lectures (see details below). This is a good opportunity for our current faculty to interact with prospective faculty. You may have been invited to attend the poster session in the afternoon of July 25th . Please consider attending it if you are free. * As we promote team building for preeminence in areas strategically important to the Weldon School, here is a quick reminder with encouragement to consider pilot initiatives at the college and university levels. For example, the TEaming for Future Grants (TEFF). To facilitate team building, Purdue Engineering is offering seed grants of up to $5k each for team-building activities to capture large (>$1M) external sponsored program opportunities with deadlines in AY 23-24 or beyond. Please reach out to Wayne Chen, Associate Dean for Research and Innovation for further details. UPCOMING IMPORTANT DATES Week of July 17 Tues., July 18: BME Master's Defense Announcement for Clarisse Zigan (D. Chan, Advisor), 3:00 p.m., MJIS 2001 and via Zoom. Title of presentation: Exploring Changes to Matrix Mechanics and Composition of Chondrocyte-laden Hydrogels. Wed., July 19: BME Summer Seminar Series, 9:30 a.m., via Zoom. Cameron Villarreal (Deva Chan, advisor) will present "The gut microbiome modulates the structure-function relationship in musculoskeletal tissue: More than a gut feeling." Jae Young Park (Hugh Lee, advisor) will present "Novel stretchable thin-film electronic device-based neuromodulation platforms for less risky, easy, and reliable implantation." MJIS UPDATES July 26, 27 and 28, the vacuum pumps will be shut down for replacement and repairs. During this three day period, there will be NO vacuum exhausting available in any of the lab hoods, as the vacuum lines to the building will be shut down in order to do needed repairs and install new piping and motors. Please plan ahead! Contact Susan Hardy (hardy13(a)purdue.edu<mailto:hardy13@purdue.edu>) with any questions or concerns. Important deadlines and information Mon., July 24: Final Grade Entry Begins. (Ends promptly at 5:00 p.m., Tues., August 8th). Wed., July 26: Trailblazers in Engineering Keynote Lecture, 8:30-9:30 a.m., The Convergence Center, 101 Foundry Dr., Suite 120. Cato T. Laurencin, University Professor at the University of Connecticut and Chief Executive Officer of the Cato T. Laurencin Institute for Regenerative Engineering at the University of Connecticut will present "Regenerative Engineering: Chemistry and Materials Science in Regeneration." Wed., July 26: Trailblazers in Engineering Keynote Lecture, 10:15-11:15 a.m., The Convergence Center, 101 Foundry Dr., Suite 120. Cecilia Aragon, Professor and Director of the Human-Centered Data Science Lab, University of Washington, Seattle, will present "What Flying Upside Down Taught Me About Engineering AI." Mon., July 31: Prospective BME Faculty Seminar, 9:30 a.m., MJIS 1083 or via Zoom. Cheen Euong Ang, Postdoctoral Research, Department of Chemistry and Chemical Biology, Harvard University, will present "Illuminating neurobiology and pathology by cellular reprogramming and spatial omics." Wed., Aug. 9: Poster Presentation Applications Deadline. Registration<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fclick.e.i…> is open for this year's Indiana CTSI Annual Meeting to be held in-person, with virtual option, 2023 Indiana CTSI Annual Meeting on September 22, 2023. As you know, this year's 2023 August M. Watanabe Prize in Translational Research Awardee<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fclick.e.i…>, Huda Y. Zoghbi, MD, is our keynote speaker. Dr. Zoghbi<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fclick.e.i…>is a Distinguished Service Professor at Baylor College of Medicine, director of the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital and an investigator with Howard Hughes Medicine Institute. In honor of this year's Watanabe Awardee, Dr. Zoghbi, our annual meeting theme will focus on translational neuroscience. Thus we will be showcasing the Indiana CTSI's cutting-edge research in neuroscience and related topics from across all our campuses. Importantly, as part of the day's agenda, we responded to your feedback and have dedicated a separate poster session along with more opportunities for networking and building collaborations. Our complete program is being finalized so please view the <https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fclick.e.i…> website<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fclick.e.i…> to stay informed. We are accepting submissions for in-person poster presentations. Research topics across the translational spectrum are welcome. Come showcase your research that is making a difference! The deadline for submitting poster presentation applications is 5:00 pm EDT on Wednesday, August 9th. More information is available via the registration link above - please note that you must register first in order to receive poster submission details. We look forward to seeing you on September 22 as we highlight the great work and people of the Indiana CTSI, and celebrate our efforts to advance health research in Indiana and beyond. Wed., Sept. 6: BMES Early Bird Registration Deadline! Register now to lock in savings with early-bird pricing for the 2023 BMES Annual Meeting (to be held in Seattle, WA, October 11-14). Thousands of biomedical engineers will attend this year's meeting to learn, collaborate, and network. As a BMES member, you can save more than 10% with reduced early bird rates, so if you're not already a member, now would be a good time to join! Click here for details: https://mailchi.mp/e3958bb463f2/o8cvhb9q5x-9335625?e=ea10e317a2<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmailchi.m…> NOTE: We recommend booking your room at the Hyatt Regency Seattle because it's closer to the convention center AND it's where university receptions will be held (in addition to some being held inside the convention center). Here's the link to reserve with the $259 discount rate. This rate only lasts until the allotted number of rooms have been sold. https://www.hyatt.com/en-US/group-booking/SEARS/G-BMES<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.hyatt…> Fri., Sept. 8: Abstract Submission Deadline for The Trauma THOMPSON Challenge. The primary goal of The Trauma THOMPSON Challenge is to encourage research to build better algorithms for autonomous instruction systems in uncontrolled and austere environments, especially for life-saving procedures. The envisioned algorithms include action recognition, action anticipation, procedure recognition, and visual question answering (VQA). The challenge participation details are below. Committee Updates Academic Programs Update Summer Grading Deadlines: 1. Final Grading windows are found here<https://www.purdue.edu/registrar/faculty/grading/index.html>: * Full 12-week summer session (includes all undergrad and grad-level research students) * Grade entry begins at 8 a.m. Monday July 24th and ends promptly at 5 p.m. Tuesday August 8th. 2. [cid:image002.png@01D9B979.D02976E0] Guidance on Final grading<https://nam04.safelinks.protection.outlook.com/ap/w-59584e83/?url=https%3A%…> 3. Now is the perfect time for faculty to take the 15 minutes to get all your required certifications up to date BEFORE the deadline approaches. * FERPA * GLBA * Data Handling * Protecting SSNs 4. This page<https://www.purdue.edu/registrar/faculty/grading/PWL-grade-entry-update.htm…> provides myPurdue grade entry instructions. 5. This page<https://www.purdue.edu/brightspace/Docs/Grades/SubmitFinalGradesToBanner.ph…> provides BrightSpace final grade submission instructions. * Those not making the deadline must use the Grade Change Workflow to submit a grade for each student. * Instructions may be found here<https://www.purdue.edu/registrar/faculty/grading/Grade_Change_Workflow.html…>. Resources and further information BME Master's Defense Announcement for Clarisse Zigan (D. Chan, Advisor), Tues., July 18, 3:00 p.m., MJIS 2001 and via Zoom. Title of presentation: Exploring Changes to Matrix Mechanics and Composition of Chondrocyte-laden Hydrogels. Committee: Dr. Deva Chan, Chair; Dr. Alex Chortos, Dr. Douglas Brubaker Abstract: To explore the mechanisms of cellular mechanotransduction, it is necessary to employ biomaterials that effectively merge biofunctionality with appropriate mechanical characteristics. Agarose is a standard biopolymer used in cartilage mechanobiology but lacks necessary adhesion motifs for cell-matrix interactions to complete mechanostransduction studies. Collagen type I is a natural biomaterial used in cartilage mechanotransduction studies but creates an environment much softer than native cartilage tissue. In these studies, agarose is blended at two final concentrations (2% w/v and 4% w/v) with collagen type I (2 mg/mL). Our ultimate goal is to determine whether a composite hydrogel of agarose and collagen can create a mechanically and biologically suitable matrix for chondrocyte studies. First, hydrogels were characterized by rheologic and compressive properties, contraction, and structural homogeneity. Following baseline characterization, primary murine chondrocytes were embedded (1 x 106 cells/mL) within the hydrogels to assess the longer-term in vitro impact on matrix mechanics, cell proliferation, sulfated glycosaminoglycan (sGAG) content, and cellular morphology. To begin probing questions about physiologic loading conditions that chondrocytes experience in vivo, a custom compression loading system was validated using cell-laden hydrogels. Briefly, the 4% agarose - 2mg/mL collagen I hydrogel composites were able to retain chondrocyte morphology over 21 days in culture, resulted in continual sGAG production, and had bulk mechanics similar to that of the stiffest hydrogel material tested, indicating this hydrogel class may be promising towards developing an effective hydrogel for chondrocyte mechanotransduction and mechanobiology studies, a critical step towards a fuller understanding of cell-matrix interactions. Zoom link: https://purdue-edu.zoom.us/j/99312080091?pwd=RnBkMSs3eHViZ0F3Kyt4Vlhqdld2UT…<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-ed…> Meeting ID: 993 1208 0091 Passcode: 411736 BME Summer Seminar Series, Wed., July 19, 9:30 a.m., via Zoom. Cameron Villarreal (Deva Chan, advisor) will present "The gut microbiome modulates the structure-function relationship in musculoskeletal tissue: More than a gut feeling." Jae Young Park (Hugh Lee, advisor) will present "Novel stretchable thin-film electronic device-based neuromodulation platforms for less risky, easy, and reliable implantation." The gut microbiome modulates the structure-function relationship in musculoskeletal tissue: More than a gut feeling, Cameron Villarreal (Deva Chan, advisor) Abstract: The gut microbiome is a diverse and dynamic ecosystem that modulates numerous physiological processes across organ systems. Microbes and microbe metabolites have been shown to alter systemic inflammation, intestinal permeability, and nutrient metabolism. Each of these processes can be associated with musculoskeletal development and the underlying structure-function relationship in the various connective tissues of the musculoskeletal system. Beyond these indirect relationships, other work has shown that modulation of the gut microbiome in rodents by introducing a high-fat diet or antibiotics leads to an altered propensity for musculoskeletal diseases like osteoarthritis and altered bone material properties. While a wealth of evidence suggests that the gut microbiome has a widespread systemic effect in the musculoskeletal system, how it modulates the connective tissue in joints and underlying subchondral bone remains poorly understood hindering our ability to diagnose, treat, and prevent musculoskeletal disease. Through our work, we aim to examine how deviations from a steady state gut microbiome, or dysbiosis, may result in deleterious changes to bone quality, cartilage content, and markers of systemic inflammation. We examine alterations to the structure-function relationship in musculoskeletal tissue through a combination of imaging, biomechanics, and content assays. Additionally, we profile the gut microbiome through 16s with the goal of correlating changes in the gut microbiome to altered gut composition. This work seeks to enhance our understanding of the interrelatedness between the gut and the musculoskeletal system to enable improved treatment, both adjuvant and preventative, of musculoskeletal disease and injury. Evaluation link for Cameron Villarreal: https://purdue.ca1.qualtrics.com/jfe/form/SV_0eUiKgdroT1urJQ<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca…> Novel stretchable thin-film electronic device-based neuromodulation platforms for less-risky, easy, and reliable implantation, Jae Young Park (Hyowon Lee, advisor) Abstract: Neuromodulation is increasingly utilized to rehabilitate a variety of biological functions, such as vision, hearing, movement, touch perception, and sense of self-movement, particularly in patients with severe or chronic diseases for whom other treatment options, including medication, have proven ineffective. Nevertheless, due to concerns about the cost and safety of surgical processes, many are hesitant to proceed with this option. Concerns particularly arise from the potential displacement of the electrode caused by movements at the target site due to air infiltration or cerebrospinal fluid loss during surgery. Other issues including technical errors, failure in lead fixation, Twiddler syndrome, and Pneumocephalus can also result in electrode dislocation. This misalignment can lead to off-target effect that can have severe repercussions for patients. In address these issues, we have developed two novel platforms and accompanying surgical strategies to enable safer, more accurate, and easier implantation: 1. Flexible electronic catheter for Deep Brain Stimulation (DBS) 2. Adhesive-hydrogel-integrated cuff electrodes for Vagus Nerve Stimulation (VNS). To achieve these multifaceted objectives, we designed a stretchable thin-film electronic device using polyimide-based microfabrication techniques, which is compliant to other functional medical platforms. By integrating this device with silicone catheter and adhesive hydrogel, we have endowed the device with new functionality that facilitate novel implantation methodologies. Evaluation link for Jae Young Park: https://purdue.ca1.qualtrics.com/jfe/form/SV_9p2aSOZR6u81LbE<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca…> *Join Zoom Meeting: https://purdue-edu.zoom.us/j/98231659969?pwd=T21Oa1B6QzFyQzFvckMzS1doNGlJUT…<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-ed…> Meeting ID: 982 3165 9969 Passcode: biomedical Trailblazers in Engineering Keynote Lecture, Wed., July 26, 8:30-9:30 a.m., The Convergence Center, 101 Foundry Dr., Suite 120. Cato T. Laurencin, University Professor at the University of Connecticut and Chief Executive Officer of the Cato T. Laurencin Institute for Regenerative Engineering at the University of Connecticut will present "Regenerative Engineering: Chemistry and Materials Science in Regeneration." Abstract: We define the field of Regenerative Engineering as the Convergence of Advanced Materials Science, Stem Cell Science, Physics, Developmental Biology, and Clinical Translation for the regeneration of complex tissues and organ systems. Work in the area of musculoskeletal tissue regeneration has focused on a number of technologies. Polymeric nanofiber systems create the prospect for biomimetics that recapitulate connective tissue ultrastructure allowing for the design of biomechanically functional matrices, and next generation matrices that create a niche for stem cell activity. Polymer and polymer-ceramic systems can be utilized for the regeneration of bone. Through the use of inducerons, small molecules fostering induction, the design of regeneration-inducing materials can be realized. Hybrid matrices possessing micro and nano architecture can create advantageous systems for regeneration, while the use of classic principles of chemistry, materials science, and engineering can lead to the development of three-dimensional systems suitable for functional regeneration of tissues. Work in the creation of synthetic artificial stem cells present prospects for joint restoration. Through convergence of a number of technologies, we believe the prospect of engaging future grand challenges is possible. Biography: Cato T. Laurencin, M.D., Ph.D. earned his B.S.E. in Chemical Engineering from Princeton, his M.D., Magna Cum Laude, from the Harvard Medical School, and his Ph.D. in Biochemical Engineering/Biotechnology from M.I.T. He is the pioneer of the field of Regenerative Engineering. In receiving the Spingarn Medal, he was named the world's foremost engineer-physician-scientist. Dr. Laurencin pioneered the novel use of polymeric biomaterials for treating musculoskeletal conditions. In recognition of his breakthrough achievements, the American Institute of Chemical Engineers created the Cato T. Laurencin Regenerative Engineering Founder's Award. Dr. Laurencin's work spans fundamental science, applied science, engineering and technology translation. He has received the highest honors in all areas including Chemistry (Priestley Medal), Materials Science (Von Hippel Award), Chemical Engineering (Founder's Award). Biological Engineering (Jay Bailey Award), Biomedical Engineering (Pritzker Lectureship Award), Medical and Biological Engineering (Pierre Galletti Award) and Surgery (Nicolas Andry Award). In science, engineering, medicine, and innovation, he is an elected member of the National Academy of Sciences, the National Academy of Engineering, the National Academy of Medicine, and an elected Fellow of the National Academy of Inventors. He is the first surgeon in history to be elected to all four national academies. Dr. Laurencin received the Philip Hague Abelson Prize, the highest honor of the American Association for the Advancement of Science, for "signal contributions to the advancement of science in the United States" for his work in Regenerative Engineering. He is the first person to receive both the oldest/highest award from the National Academy of Engineering (the Simon Ramo Founder's Award) and one of the oldest/highest awards of the National Academy of Medicine (the Walsh McDermott Medal). In innovation, Dr. Laurencin was awarded the National Medal of Technology and Innovation, America's highest honor for technological advancement, by President Barack Obama in ceremonies at the White House. Dr. Laurencin is the University Professor and Albert and Wilda Van Dusen Distinguished Endowed Professor at the University of Connecticut. He is Professor of Chemical and Biomolecular Engineering, Professor of Materials Science and Engineering and Professor of Biomedical Engineering at UConn. He is the Chief Executive Officer of the Cato T. Laurencin Institute for Regenerative Engineering at UConn. His autobiography has been published by Elsevier. It is entitled "Success is What You Leave Behind''. Please scan the QR code to register. After registering, you will receive a confirmation email containing information about joining the meeting. [cid:image003.png@01D9B979.D02976E0] Hosted by the College of Engineering. Trailblazers in Engineering Keynote Lecture, Wed., July 26, 10:15-11:15 a.m., The Convergence Center, 101 Foundry Dr., Suite 120. Cecilia Aragon, Professor and Director of the Human-Centered Data Science Lab, University of Washington, Seattle, will present "What Flying Upside Down Taught Me About Engineering AI." Abstract: In this talk, Cecilia Aragon describes her journey from extremely fearful daughter of immigrants to daredevil airshow pilot - and then to using supercomputers and human-centered artificial intelligence to solve some of the greatest mysteries of the universe. She'll present examples from a 30-year career in data science, artificial intelligence, and aviation and talk about how using math to face her fears enabled her to become the first Latina pilot on the US Unlimited Aerobatic Team. She scaffolded that courage to build a career in data science and Al, developing the new field of human-centered data science and becoming the first Latina to achieve the rank of Full Professor in the College of Engineering at the University of Washington in its 100-year history. Biography: Dr. Cecilia Aragon is an award-winning author, airshow pilot, and the first Latina to earn the rank of Full Professor in the College of Engineering at the University of Washington in its 100-year history. She earned her Ph.D. in Computer Science from UC Berkeley in 2004, and her B.S. in Mathematics from the California Institute of Technology. She's worked with Nobel Prize winners and has taught astronauts to fly. Her innovative research, and a stint at NASA designing software for Mars missions, led President Obama to call her "one of the top scientists and engineers in the country:' In addition to her love of math and science, she's passionate about helping others face their own fears and challenges to achieve their goals. Her award-winning memoir, Flying Free (2020), shares her journey of breaking past her own fears to become a champion aerobatic pilot. It debuted on five bestseller lists and is a TODAY Show and Hip Latina Recommended Read, and winner of the 2021 Nancy Pearl Award from the Pacific Northwest Writers Association and the International Latino Book Award Gold Medal for Most Inspirational Nonfiction in English .. Her 2019 book, Writers in the Secret Garden, takes a close look at the fascinating world of fanfiction to explore how young people express themselves. Her latest book, Human-Centered Data Science (2022), is an accessible guide to best practices for addressing bias and inequality in data science and artificial intelligence. Learn more at CeciliaAragonAuthor.com. Please scan the QR code to register. After registering, you will receive a confirmation email containing information about joining the meeting. [cid:image004.png@01D9B979.D02976E0] Hosted by the College of Engineering. Prospective BME Faculty Seminar, Mon., July 31, 9:30 a.m., MJIS 1083 or via Zoom. Cheen Euong Ang, Postdoctoral Researcher, Department of Chemistry and Chemical Biology, Harvard University, will present "Illuminating neurobiology and pathology by cellular reprogramming and spatial omics." Abstract: Genome-wide association studies have revealed single nucleotide polymorphism and copy number variants associated with neurological diseases. Generally, mutations in the coding genes are decipherable based on our knowledge of splicing and the genetic code. However, how mutations in the regulatory elements or non-coding RNAs contribute to neurological diseases remain an open area of investigation. Elucidating how non-coding regions contribute to pathogenesis is hindered by: (a) the lack of access to healthy or diseased human brain tissue samples and (b) the lack of tools to visualize the spatial activity of regulatory elements and non-coding RNAs within the nucleus and across brain tissue and how their spatial activity regulates gene expression. In the first part of my talk, I will describe the development of reprogramming protocols to obtain human neurons via direct conversion of somatic or embryonic stem cells into induced neurons and the use of those neurons to model a non-coding RNA mutation found in autism spectrum disorder patients. Additionally, I will present my recent work in developing spatial transcriptomic and epigenomic imaging methods to shed light on gene regulation and enhancer dynamics during nervous system development. The research presented showcases the promise of using neuronal reprogramming and spatial imaging to deepen our understanding of neurodevelopmental processes and the role of non-coding mutations in neurological diseases, potentially informing the future development of new therapeutic strategies. 1. Tanabe, K.*, Ang, C.E.*, Chanda, S., Levinson, D., Sudhof, T.C., & Wernig, M. Transdifferentiation of human adult peripheral blood T cells into neurons. PNAS. 115 (25) 6470-6475. (2018). 2. Ang, C.E.*, Wapinski, O.*, Ma, Q.*, Fan, S., Coe, B., Onoguchi, M., Do, B.T., Dukes-Rimsky, L., Xu, J., Lee, Q.Y., Wang, L., Eichler, E.E., Srivastava, A., Elling, U., Penninger, J., Wernig, M., & Chang, H.Y. The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders. eLife. 2019;8: e41770 (2019) 3. Lu, T.*, Ang, C.E.*, Zhuang, X. Spatially resolved epigenomic profiling of single cells in complex tissues. Cell. 185, 117. (2022). 4. Wang, G., Ang, C.E., Fan, J., Wang, A., Moffitt, J.R., Zhuang, X. Spatial organization of the transcriptome in individual neurons. In revision. https://www.biorxiv.org/content/10.1101/2020.12.07.414060v1.abstract<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.biorx…> Zoom link: https://purdue-edu.zoom.us/j/95037790369<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-ed…> [Indiana CTSI logo and co-directors logo] REGISTRATION NOW OPEN FOR THE 2023 INDIANA CTSI ANNUAL MEETING PLEASE JOIN US ON FRIDAY, SEPTEMBER 22, 2023! Dear Indiana CTSI Colleagues, As announced today in a communication to our Indiana CTSI newsletter subscribers, registration<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fclick.e.i…> is open for this year's Indiana CTSI Annual Meeting to be held in-person, with virtual option, 2023 Indiana CTSI Annual Meeting on September 22, 2023. As you know, this year's 2023 August M. Watanabe Prize in Translational Research Awardee<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fclick.e.i…>, Huda Y. Zoghbi, MD, is our keynote speaker. Dr. Zoghbi<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fclick.e.i…>is a Distinguished Service Professor at Baylor College of Medicine, director of the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital and an investigator with Howard Hughes Medicine Institute. In honor of this year's Watanabe Awardee, Dr. Zoghbi, our annual meeting theme will focus on translational neuroscience. Thus we will be showcasing the Indiana CTSI's cutting-edge research in neuroscience and related topics from across all our campuses. Importantly, as part of the day's agenda, we responded to your feedback and have dedicated a separate poster session along with more opportunities for networking and building collaborations. Our complete program is being finalized so please view the <https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fclick.e.i…> website<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fclick.e.i…> to stay informed. We are accepting submissions for in-person poster presentations. Research topics across the translational spectrum are welcome. Come showcase your research that is making a difference! The deadline for submitting poster presentation applications is 5:00 pm EDT on Wednesday, August 9th. More information is available via the registration link above - please note that you must register first in order to receive poster submission details. We look forward to seeing you on September 22 as we highlight the great work and people of the Indiana CTSI, and celebrate our efforts to advance health research in Indiana and beyond. Please register now and encourage others to do so! Sarah and Sharon Co-directors, Indiana Clinical and Translational Sciences Institute ictsi(a)iupui.edu<mailto:ictsi@iupui.edu?subject=> Attachments: LBA 2023 Artificial Intelligence Overview -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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[Bmeroundtable-list] MJIS Vaccuum pump shutdown
by Gelfand, Johanna K 17 Jul '23

17 Jul '23

July 26, 27 and 28, the vacuum pumps will be shut down for replacement and repairs. During this three day period, there will be NO vacuum exhausting available in any of the lab hoods, as the vacuum lines to the building will be shut down in order to do needed repairs and install new piping and motors. Please plan ahead! Contact Susan Hardy (hardy13(a)purdue.edu<mailto:hardy13@purdue.edu>) with any questions or concerns. -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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[Bmeroundtable-list] Summer Seminar Announcement
by Rowen, Elizabeth Pearl 14 Jul '23

14 Jul '23

Hello, I am sending the following summer seminar announcement to go out today (Friday, 7-14-23) and also to be included in the Round Table announcements on Monday 7-17. Thanks! Liz [cid:image001.jpg@01D9B5A0.FE4AF3A0] BME Summer Seminar Series Wednesday, July 19th, 2023 9:30-10:30 AM EST Via Zoom Meeting - link below* Evaluation links: Cameron Villarreal: https://purdue.ca1.qualtrics.com/jfe/form/SV_0eUiKgdroT1urJQ<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca…> Jae Young Park: https://purdue.ca1.qualtrics.com/jfe/form/SV_9p2aSOZR6u81LbE<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca…> The gut microbiome modulates the structure-function relationship in musculoskeletal tissue: More than a gut feeling Cameron Villarreal (Deva Chan, advisor) [Cameron Villarreal] Abstract: The gut microbiome is a diverse and dynamic ecosystem that modulates numerous physiological processes across organ systems. Microbes and microbe metabolites have been shown to alter systemic inflammation, intestinal permeability, and nutrient metabolism. Each of these processes can be associated with musculoskeletal development and the underlying structure-function relationship in the various connective tissues of the musculoskeletal system. Beyond these indirect relationships, other work has shown that modulation of the gut microbiome in rodents by introducing a high-fat diet or antibiotics leads to an altered propensity for musculoskeletal diseases like osteoarthritis and altered bone material properties. While a wealth of evidence suggests that the gut microbiome has a widespread systemic effect in the musculoskeletal system, how it modulates the connective tissue in joints and underlying subchondral bone remains poorly understood hindering our ability to diagnose, treat, and prevent musculoskeletal disease. Through our work, we aim to examine how deviations from a steady state gut microbiome, or dysbiosis, may result in deleterious changes to bone quality, cartilage content, and markers of systemic inflammation. We examine alterations to the structure-function relationship in musculoskeletal tissue through a combination of imaging, biomechanics, and content assays. Additionally, we profile the gut microbiome through 16s with the goal of correlating changes in the gut microbiome to altered gut composition. This work seeks to enhance our understanding of the interrelatedness between the gut and the musculoskeletal system to enable improved treatment, both adjuvant and preventative, of musculoskeletal disease and injury. Novel stretchable thin-film electronic device-based neuromodulation platforms for less-risky, easy, and reliable implantation Jae Young Park (Hyowon Lee, advisor) [Jae Young Park] Abstract: Neuromodulation is increasingly utilized to rehabilitate a variety of biological functions, such as vision, hearing, movement, touch perception, and sense of self-movement, particularly in patients with severe or chronic diseases for whom other treatment options, including medication, have proven ineffective. Nevertheless, due to concerns about the cost and safety of surgical processes, many are hesitant to proceed with this option. Concerns particularly arise from the potential displacement of the electrode caused by movements at the target site due to air infiltration or cerebrospinal fluid loss during surgery. Other issues including technical errors, failure in lead fixation, Twiddler syndrome, and Pneumocephalus can also result in electrode dislocation. This misalignment can lead to off-target effect that can have severe repercussions for patients. In address these issues, we have developed two novel platforms and accompanying surgical strategies to enable safer, more accurate, and easier implantation: 1. Flexible electronic catheter for Deep Brain Stimulation (DBS) 2. Adhesive-hydrogel-integrated cuff electrodes for Vagus Nerve Stimulation (VNS). To achieve these multifaceted objectives, we designed a stretchable thin-film electronic device using polyimide-based microfabrication techniques, which is compliant to other functional medical platforms. By integrating this device with silicone catheter and adhesive hydrogel, we have endowed the device with new functionality that facilitate novel implantation methodologies. *Join Zoom Meeting https://purdue-edu.zoom.us/j/98231659969?pwd=T21Oa1B6QzFyQzFvckMzS1doNGlJUT…<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-ed…> Meeting ID: 982 3165 9969 Passcode: biomedical Liz Rowen She/Her Graduate Program Assistant Weldon School of Biomedical Engineering Martin C. Jischke Hall of Biomedical Engineering 206 S. Martin Jischke Drive West Lafayette, IN 47907-2032 o: 765-494-1197 [7054E290]<https://www.purdue.edu/?utm_source=signature&utm_medium=email&utm_campaign=…> -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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Weldon Graduate Program Announcements July 12th, 2023
by Siemers, Tammy R 12 Jul '23

12 Jul '23

[4,354 Breaking News Photos and Premium High Res Pictures - Getty Images] Weldon Graduate Program Announcements July 12th, 2023 * Career and Internship Opportunities * IU Bloomington: The Mathematical Sciences in Obesity Research Course (July 31st - August 4th) * Fall Pass/No Pass Grant Writing Class Open to All Graduate Students * Graduate Professional Development Newsletter (July 7) * BMES Student Volunteer Program Opens Today! (Apply by Aug. 3rd) * Postdoc Opinion Piece: Why I love my postdoc position at an independent research institute * Workshops and Deadlines * News from You Career and Internship Opportunities Internship Positions * 2023 Co-op Chemical & Biomedical Engineering, Regeneron<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fregeneron…> * Electrical Engineering Co-op, Vivonics<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fstatic1.s…> * V&V Engineering Co-op, Mammotome<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fjobs.dana…> Postdoctoral Positions * NPA Website: https://careers.nationalpostdoc.org/jobs/<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fcareers.n…> Full Time Positions * Researcher V, University of Alabama<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fuab.taleo…> * Data Science and Algorithms Engineer, Medtronic<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmedtronic…> * Biomedical Engineer I or II, HJF<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fcareers-h…> * Senior Engineer, R&D, BD<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fjobs.bd.c…> * Product Design Engineer, Upper Extremities, Exactech<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fexactech.…> * R&D Engineer 2, RTI Surgical<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.simpl…> * Process Engineer II, Thermo Fischer<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fjobs.ther…> * Associate Scientist, Antibody Engineering, Neurocrine Biosciences<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fneurocrin…> * Product Engineer II, Medtronic<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmedtronic…> * Associate Scientist, Protein Engineering, BioMap<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.simpl…> * Systems Engineer, Talis Biomedical Corporation<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.simpl…> * Research Engineer II, IDEA, Texas Heart Institute<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.simpl…> * Clinical Engineer, Biomedical Engineering, Mass General Brigham<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpartners.…> * Engineer II, Systems, Boston Scientific<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fjobs.bost…> * Purdue Start-up Job Board<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurduefou…>-Foundry Start Up Companies Looking to Hire * ACTS Career Center<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fcareers.a…>-Association for Clinical and Translational Science * Academic Careers<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Facademicc…> * Doc Jobs<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.docjo…>-Jobs beyond traditional clinical and academic roles IU Bloomington: The Mathematical Sciences in Obesity Research Course (July 31st - August 4th) We have spots available and are continuously reviewing applications. There are travel scholarships still available. The Mathematical Sciences in Obesity Research Dates: Monday, July 31st - Friday, August 4th Format: In-person, Monday through Friday, Bloomington, IN, 8 AM to 5PM EST. Course description: The mathematical sciences including engineering, statistics, computer science, physics, econometrics, psychometrics, epidemiology, and mathematics qua mathematics are increasingly being applied to advance our understanding of the causes, consequences, and alleviation of obesity. These applications do not merely involve routine, well-established approaches easily implemented in widely available commercial software. Rather, they increasingly involve computationally demanding tasks, use and development of novel analytic methods and software, new derivations, computer simulations, and unprecedented interdigitation of two or more existing techniques. Such advances at the interface of the mathematical sciences and obesity research require bilateral training and exposure for investigators in both disciplines. To apply: Visit our course site at The Mathematical Sciences in Obesity<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Ftraining.…> Fall Pass/No Pass Grant Writing Class Open to All Graduate Students See attached For fall 2023: GRAD 59000-030: Grant Writing "Light" Version 1.0 credit hours, pass-no pass asynchronous and online CRN 24427 Graduate Professional Development Newsletter (July 7) Graduate Professional Development Newsletter (July 7)<https://mailimages.purdue.edu/vo/?FileID=809521db-877f-45be-9316-feb1aeb739…> BMES Student Volunteer Program Opens Today! (Apply by Aug. 3rd) BMES Student Volunteer Program Opens Today!<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmailchi.m…> Postdoc Opinion Piece: Why I love my postdoc position at an independent research institute Why I love my postdoc position at an independent research institute<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.natur…> Workshops and Deadlines Here are some upcoming workshops and deadlines more detailed information about the workshops will be sent out separately closer to the event. July 14th RCR: Discipline-Specific Training (Enroll Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgspd.gosi…>) July 14th Dr. Eliseo Perez-Stable: My Career Path to NIHMD: Health Disparities & Diversity (Register<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.train…>) July 18th Publishing a Scientific Paper (Enroll Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgspd.gosi…>) July 18th NSF Fellowship Life Sciences Panel (Enroll Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgspd.gosi…>) July 18th NSF Fellowship Physical and Computational Sciences Panel (Enroll Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgspd.gosi…>) July 18th Fellowship Office Hour for Grad Students and Postdocs (Enroll Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgspd.gosi…>) July 19th NSF Fellowship Engineering Panel (Enroll Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgspd.gosi…>) July 19th NSF Fellowship Social Sciences and Education Panel (Enroll Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgspd.gosi…>) July 19th NIH Graduate & Professional School Fair (Register Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.train…>) July 20th NSF Fellowship Agriculture Panel (Enroll Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgspd.gosi…>) July 20th Business Meal Etiquette (Enroll Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgspd.gosi…>) July 20th NSF Fellowship Help Session (Enroll Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgspd.gosi…>) July 24th Budgeting and Saving Money (Enroll Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgspd.gosi…>) July 24th-Aug. 1st Virtual NIH Graduate & Professional School Fair (Register Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.train…>) July 25th Computational Fellowships Info Session (Enroll Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgspd.gosi…>) July 26th How to Find and Prepare for Fellowship Applications (Enroll Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgspd.gosi…>) July 26th NDSEG (Defense Research) Fellowship Info Session (Enroll Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgspd.gosi…>) July 27th Postdoc Grant Writing: All About NSF (Enroll Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgspd.gosi…>) July 27th NSF Fellowship Help Session (Enroll Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgspd.gosi…>) July 24th-25th Facilitating Entering Mentoring Workshop (CIMER<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fsites.goo…>) Aug. 3rd Deadline to apply for BMES Student Volunteer Program (Apply Here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.bmes.…>) Aug. 11th Deadline to apply for Stanford Biodesign Innovation Fellowship (Apply here<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fbiodesign…>) News from You Please inform Tammy of honors, awards, or other accolades (to include having a paper published) you receive so that the Weldon School may recognize your accomplishments. Send the complete information - specific title and nature of the award, name of conference or event at which award was given, date of said event, photograph if available, etc. - to tsiemers(a)purdue.edu<mailto:tsiemers@purdue.edu>. Tammy Siemers She/Her Associate Director, Graduate Education Weldon School of Biomedical Engineering 206 S. Martin Jischke Drive, West Lafayette, IN 47907-2032 o: 765-496-0294 Achiever, Relator, Includer, Restorative, Developer [233FFCD4]<https://www.purdue.edu/?utm_source=signature&utm_medium=email&utm_campaign=…>

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[Bmeroundtable-list] FW: Trailblazers in Engineering Keynote Speaker - Dr. Cecilia Aragon - July 26, 2023, at 10:15-11:15 AM, The Convergence Center
by Gelfand, Johanna K 12 Jul '23

12 Jul '23

Another seminar you may find of interest. [cid:0d799e33-7fbe-4c42-b2ab-c4a19f2ccc3f@namprd22.prod.outlook.com] -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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[Bmeroundtable-list] Parking closure
by Gelfand, Johanna K 12 Jul '23

12 Jul '23

The back lot (between Herrick and MJIS) has been closed for repair. Sorry for the short notice - we did not receive any advanced notice. -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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[Bmeroundtable-list] Trailblazers in Engineering Keynote Speaker - Dr. Cato T. Laurencin - July 26, 2023, at 8:30-9:30 AM, The Convergence Center
by Gelfand, Johanna K 12 Jul '23

12 Jul '23

From: Longoria-Littleton, Maria <mlongori(a)purdue.edu> Sent: Tuesday, July 11, 2023 4:29 PM To: Kong, Nan <nkong(a)purdue.edu> Subject: Trailblazers in Engineering Keynote Speaker - Dr. Cato T. Laurencin - July 26, 2023, at 8:30-9:30 AM, The Convergence Center Importance: High Dr. Kong, We are excited to announce that Dr. Cato T. Laurencin<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Ffacultydi…>, The University Professor and Albert and Wilda Van Dusen Distinguished Endowed Professor at the University of Connecticut, Professor of Chemical and Biomolecular Engineering, Professor of Materials Science and Engineering, Professor of Biomedical Engineering at UConn, and the Chief Executive Officer of the Cato T. Laurencin Institute for Regenerative Engineering at UConn, will be one of our July 26 - Trailblazers in Engineering Keynote Speakers. Your faculty, staff, and graduate students are welcome to attend this keynote event. [cid:image001.jpg@01D99FA7.306DB030] Thank you, Maria * * * Maria Longoria-Littleton Senior Assistant Director, Faculty Success Programs College of Engineering Neil Armstrong Hall of Engineering 701 W Stadium Ave, ARMS 1253 West Lafayette, IN 47907-2045 o: 765-494-0015 m: 765-430-7176 f: 765-496-0004 -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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[Bmeroundtable-list] BME Weekly Roundtable - July 11, 2023
by Gelfand, Johanna K 11 Jul '23

11 Jul '23

[cid:image005.jpg@01D9B3EE.40890450] BME WEEKLY ROUNDTABLE July 11, 2023 INTERIM HEAD'S NOTE Greetings to all of you from my international trip. While I am visiting my extended family in Beijing for the first time in four years, I have been handling a number of burning issues as the Interim Head with great help from many of you. During my interim tenure, I want to make sure that the School continues to strive for excellence in all fronts of research, teaching, and engagement. * The search for the next permanent Head is underway. The search committee will be announced soon. I will work with many of you and the Dean's Office to facilitate a successful search. We want to find the best person to take over the baton as the leader of the School for the next many years. Under the headship of George and David, we have made great progress but we still have many places to improve. At this critical juncture, we all should think about what quality we'd like the new Head to have and which direction we would like them take us. * To ensure the smooth transition, I see my priority in the following three aspects: 1) UG teaching integration; 2) adjustment and stabilization of the graduate program policies implemented last year under Tami and Mike's leadership; 3) identification of research areas of strategic importance to the department and synergy building to well position us for center grants * For the first two priorities, Vitaliy Rayz (our new Associate Head for Academic Programs), Tamara Kinzer-Ursem and myself are in the process of finalizing our new graduate and undergraduate programs. Once the program directors are appointed, we will work on forming the committees for the coming academic year, which should be no later than the end of July. * For the third priority, I know several groups have been bouncing ideas off of each other regularly. For example, there is a group looking into AI/ML in biomedicine and healthcare. The attached report (LBA 2023 Artificial Intelligence Overview) may be interesting to many of you. Let us keep up the momentum. The key here will be to create a scenario of superadditivity within our faculty's research productivity. * In addition, I'd like to help develop a strategy of improving our professional and online Master's programs, which are critical to the financial health of our School. * Congratulations to Fang and his colleagues for passing the preproposal competition of the NSF Biofoundry within the university. Now Fang is leading the team to work toward a full proposal. More of such will be great for the School. UPCOMING IMPORTANT DATES Week of July 10 Tues., July 11: BME IBSC PhD Defense Announcement for Mazin Hakim (L. Solorio, advisor), 3:00 p.m., MJIS 2001 and via Zoom. This defense is open only to those who have signed the Lilly NDA. Title: Platforms for Molecular Mechanisms and Improvement in Subcutaneous Injection of Biotherapeutics. Advisory Committee: Luis Solorio, Chair; Arezoo M. Ardekani; Julie C. Liu; Pavlos P. Vlachos. Join Zoom Meeting https://purdue-edu.zoom.us/j/94670872770?pwd=SmxaZjFlaSs3RXVPZWZsU3d3SXhsQT…<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.googl…> Meeting ID: 946 7087 2770 Passcode: Mazin Wed., July 12: Diabetes Research Virtual Seminar Series, 2:00 p.m., via Zoom. Fiona Gribble, MD, DPhil, Professor of Endocrine Physiology, Institute of Metabolic Science, University of Cambridge, will present "Targeting the gut to treat metabolic disease." Incretin based therapies are highly successful in treating type 2 diabetes and obesity. They are based on the gut hormone GLP-1, which is released postprandially from specialized sensory endocrine cells in the intestinal epithelium. Our group studies the cellular physiology underlying the function of cells secreting gut hormones, including the molecular pathways they employ to detect ingested foods. We now have a good understanding of how these cells respond to sugars, fats and proteins in the diet, and the metabolic consequences arising following release of hormones from different regions of the gut. Zoom link: https://zoom.us/j/91323894836<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fzoom.us%2…> . This seminar is sponsored by the Indiana University School of Medicine and the Diabetes Research Centers. Sat. July 15th: Nominations submitted from faculty and staff for Purdue Engineering Fellows. The Purdue Engineering Fellows program is designed to recognize the accomplishments, contributions and potential of seven outstanding seniors who make a difference in the college and in the lives of others by bringing creative thinking to their academic activities, demonstrating distinctive problem-solving abilities, and are respected by their peers and faculty. In summary, Purdue Engineering Fellows will be students who demonstrate impressive abilities to think creatively and to develop innovative solutions to problems-whether in the classroom, in student life, or in the community. We are now asking our faculty and staff to submit nominations through the Qualtrics survey: https://purdue.ca1.qualtrics.com/jfe/form/SV_7ZZLY4ioCfXwjb0<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca…> by July 15th. Students must be in their senior year and graduating in May of 2024 (December grads are not eligible). Upon graduation, each recipient will receive $20,000 to use as they see fit. A nomination letter and copy of the student's resume are required for full consideration. Contact Darshini Render (render(a)purdue.edu) if you have questions, including verifying your student nominee eligibility. You can find information about previous Purdue Engineering Fellows here: https://engineering.purdue.edu/Engr/AboutUs/News/Spotlights/2022/2022-0923-… MJIS UPDATES Just a reminder: If you eat/snack in any of the seating areas in MJIS, please take a moment when you are finished to spray and wipe down the tables and make sure all trash is in the trash bins. We are seeing quite an infestation of ants that are attracted to food residue and crumbs! There are cleaning supplies available in each area. PLEASE remember to clean up after yourself each time. Also, we are seeing a lot of backpacks, bookbags and personal items being left in the sitting areas. The Purdue Police have notified us that the theft ring has made a reappearance on campus, and are working their way through campus building. This particular group works on a "theft by convenience" mode - entering unlocked offices, and taking whatever is readily available. If you have high school students or others working in your labs this summer, please make sure they keep their personal belongings on the provided hooks inside the secure lab block. Don't allow yourself to be the victim of a convenience crime! Important deadlines and information Tues., July 18: BME Master's Defense Announcement for Clarisse Zigan (D. Chan, Advisor), 3:00 p.m., MJIS 2001 and via Zoom. Title of presentation: Exploring Changes to Matrix Mechanics and Composition of Chondrocyte-laden Hydrogels. Mon., July 24: Final Grade Entry Begins. (Ends promptly at 5:00 p.m., Tues., August 8th). Wed., Aug. 9: Poster Presentation Applications Deadline. Registration<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fclick.e.i…> is open for this year's Indiana CTSI Annual Meeting to be held in-person, with virtual option, 2023 Indiana CTSI Annual Meeting on September 22, 2023. As you know, this year's 2023 August M. Watanabe Prize in Translational Research Awardee<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fclick.e.i…>, Huda Y. Zoghbi, MD, is our keynote speaker. Dr. Zoghbi<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fclick.e.i…>is a Distinguished Service Professor at Baylor College of Medicine, director of the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital and an investigator with Howard Hughes Medicine Institute. In honor of this year's Watanabe Awardee, Dr. Zoghbi, our annual meeting theme will focus on translational neuroscience. Thus we will be showcasing the Indiana CTSI's cutting-edge research in neuroscience and related topics from across all our campuses. Importantly, as part of the day's agenda, we responded to your feedback and have dedicated a separate poster session along with more opportunities for networking and building collaborations. Our complete program is being finalized so please view the <https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fclick.e.i…> website<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fclick.e.i…> to stay informed. We are accepting submissions for in-person poster presentations. Research topics across the translational spectrum are welcome. Come showcase your research that is making a difference! The deadline for submitting poster presentation applications is 5:00 pm EDT on Wednesday, August 9th. More information is available via the registration link above - please note that you must register first in order to receive poster submission details. We look forward to seeing you on September 22 as we highlight the great work and people of the Indiana CTSI, and celebrate our efforts to advance health research in Indiana and beyond. Wed., Sept. 6: BMES Early Bird Registration Deadline! Register now to lock in savings with early-bird pricing for the 2023 BMES Annual Meeting (to be held in Seattle, WA, October 11-14). Thousands of biomedical engineers will attend this year's meeting to learn, collaborate, and network. As a BMES member, you can save more than 10% with reduced early bird rates, so if you're not already a member, now would be a good time to join! Click here for details: https://mailchi.mp/e3958bb463f2/o8cvhb9q5x-9335625?e=ea10e317a2<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmailchi.m…> NOTE: We recommend booking your room at the Hyatt Regency Seattle because it's closer to the convention center AND it's where university receptions will be held (in addition to some being held inside the convention center). Here's the link to reserve with the $259 discount rate. This rate only lasts until the allotted number of rooms have been sold. https://www.hyatt.com/en-US/group-booking/SEARS/G-BMES<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.hyatt…> Fri., Sept. 8: Abstract Submission Deadline for The Trauma THOMPSON Challenge. The primary goal of The Trauma THOMPSON Challenge is to encourage research to build better algorithms for autonomous instruction systems in uncontrolled and austere environments, especially for life-saving procedures. The envisioned algorithms include action recognition, action anticipation, procedure recognition, and visual question answering (VQA). The challenge participation details are below. Committee Updates Academic Programs Update Summer Grading Deadlines: 1. Final Grading windows are found here<https://www.purdue.edu/registrar/faculty/grading/index.html>: * Full 12-week summer session (includes all undergrad and grad-level research students) * Grade entry begins at 8 a.m. Monday July 24th and ends promptly at 5 p.m. Tuesday August 8th. 2. [cid:image006.png@01D9B3EE.40890450] Guidance on Final grading<https://nam04.safelinks.protection.outlook.com/ap/w-59584e83/?url=https%3A%…> 3. Now is the perfect time for faculty to take the 15 minutes to get all your required certifications up to date BEFORE the deadline approaches. * FERPA * GLBA * Data Handling * Protecting SSNs 4. This page<https://www.purdue.edu/registrar/faculty/grading/PWL-grade-entry-update.htm…> provides myPurdue grade entry instructions. 5. This page<https://www.purdue.edu/brightspace/Docs/Grades/SubmitFinalGradesToBanner.ph…> provides BrightSpace final grade submission instructions. * Those not making the deadline must use the Grade Change Workflow to submit a grade for each student. * Instructions may be found here<https://www.purdue.edu/registrar/faculty/grading/Grade_Change_Workflow.html…>. Resources and further information BME Master's Defense Announcement for Clarisse Zigan (D. Chan, Advisor), Tues., July 18, 3:00 p.m., MJIS 2001 and via Zoom. Title of presentation: Exploring Changes to Matrix Mechanics and Composition of Chondrocyte-laden Hydrogels. Committee: Dr. Deva Chan, Chair; Dr. Alex Chortos, Dr. Douglas Brubaker Abstract: To explore the mechanisms of cellular mechanotransduction, it is necessary to employ biomaterials that effectively merge biofunctionality with appropriate mechanical characteristics. Agarose is a standard biopolymer used in cartilage mechanobiology but lacks necessary adhesion motifs for cell-matrix interactions to complete mechanostransduction studies. Collagen type I is a natural biomaterial used in cartilage mechanotransduction studies but creates an environment much softer than native cartilage tissue. In these studies, agarose is blended at two final concentrations (2% w/v and 4% w/v) with collagen type I (2 mg/mL). Our ultimate goal is to determine whether a composite hydrogel of agarose and collagen can create a mechanically and biologically suitable matrix for chondrocyte studies. First, hydrogels were characterized by rheologic and compressive properties, contraction, and structural homogeneity. Following baseline characterization, primary murine chondrocytes were embedded (1 x 106 cells/mL) within the hydrogels to assess the longer-term in vitro impact on matrix mechanics, cell proliferation, sulfated glycosaminoglycan (sGAG) content, and cellular morphology. To begin probing questions about physiologic loading conditions that chondrocytes experience in vivo, a custom compression loading system was validated using cell-laden hydrogels. Briefly, the 4% agarose - 2mg/mL collagen I hydrogel composites were able to retain chondrocyte morphology over 21 days in culture, resulted in continual sGAG production, and had bulk mechanics similar to that of the stiffest hydrogel material tested, indicating this hydrogel class may be promising towards developing an effective hydrogel for chondrocyte mechanotransduction and mechanobiology studies, a critical step towards a fuller understanding of cell-matrix interactions. Zoom link: https://purdue-edu.zoom.us/j/99312080091?pwd=RnBkMSs3eHViZ0F3Kyt4Vlhqdld2UT…<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-ed…> Meeting ID: 993 1208 0091 Passcode: 411736 Attachments: LBA 2023 Artificial Intelligence Overview -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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[Bmeroundtable-list] BME Welcome/Welcome Back Ice Cream Social
by Siemers, Tammy R 10 Jul '23

10 Jul '23

-- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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[Bmeroundtable-list] Save the Date: BME Welcome Back Ice Cream Social
by Siemers, Tammy R 10 Jul '23

10 Jul '23

Good Afternoon, We are once again going to host a Welcome Back (for some of you welcome to the Fall semester) Ice Cream Social on the first Friday of classes. Join us for some great conversation and yummy treats as we get the fall semester started. I will send a calendar invite to those that utilize that feature. Date: Friday, August 26th Time: 1-2 pm Location: MJIS South Lawn (rain location: MJIS 2001) I hope you consider joining us! Tammy Tammy Siemers She/Her Associate Director, Graduate Education Weldon School of Biomedical Engineering 206 S. Martin Jischke Drive, West Lafayette, IN 47907-2032 o: 765-496-0294 Achiever, Relator, Includer, Restorative, Developer [233FFCD4]<https://www.purdue.edu/?utm_source=signature&utm_medium=email&utm_campaign=…> -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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