April 2022 - Bmegradstudents-list

Weldon Graduate Program Announcements April 27, 2022
by Siemers, Tammy R 28 Apr '22

28 Apr '22

[4,354 Breaking News Photos and Premium High Res Pictures - Getty Images] Weldon Graduate Program Announcements April 27, 2022 * Career and Internship Opportunities * Opportunity to Mentor Undergrads through GradTrack * PCCR Monthly Series on Career Development: A Panel Discussion with Scientists from Eli Lilly: What an Industry Career Looks Like? * PATHFINDER: A program dedicated to career development of Purdue life scientists * Graduate Professional Development Newsletter (April 22) * NEW! Exciting Program for Students in Regulatory Education * System ID for Fall 2022 * Executive Functioning for Biomedical Researchers- May 2, 3 PM part of Mental Health Awareness Month * NIH Career Symposium May 11-13, 2022 * Fall 2022 Tech Commercialization and Entrepreneurship Course * Featured Database: Web of Science * Workshops and Deadlines * News from You Career and Internship Opportunities Internship Positions * Summer 2022 Associate Engineer, SpaceX<https://www.linkedin.com/jobs/view/3046559089/?lgTemp=jobs_jymbii_digest&eB…> Postdoctoral Positions * NPA Website: https://careers.nationalpostdoc.org/jobs/ Full time Positions * Biomedical Engineer, LivaNova<https://www.linkedin.com/jobs/view/3021210526/?lgTemp=jobs_jymbii_digest&eB…> * Biomedical Engineer, Onocyte Corporation<https://www.linkedin.com/jobs/view/2914763884/?alternateChannel=search&refI…> * Senior Manufacturing Process Engineer, Cook Advanced Technologies<https://americas-cookmedical.icims.com/jobs/10623/senior-manufacturing-proc…> * Senior Mechanical Design Engineer, Cook Advanced Technologies<https://americas-cookmedical.icims.com/jobs/10601/senior-mechanical-design-…> * Mechanical Engineer, Cook Advanced Technologies<https://americas-cookmedical.icims.com/jobs/9776/mechanical-engineer/job> * Research and Development Engineer, Cook Advanced Technologies<https://americas-cookmedical.icims.com/jobs/9322/research-%26-development-e…> * Regulatory Scientist, Cook Advanced Technology<https://americas-cookmedical.icims.com/jobs/9562/regulatory-scientist/job> * Biomedical Engineer II, True Digital Surgery<http://jobs.truedigitalsurgery.com/apply/sXYla0Qaqw/Biomedical-Engineer-II?…> * Research Scientist, Protein Engineering, Stanford<https://careersearch.stanford.edu/jobs/research-scientist-protein-engineeri…> * Product Development Engineer, Viant<https://www.simplyhired.com/job/EnF3Da-DGyVm8ef74vNsUP3pkG9QI5xOqVfujmdgG1N…> * Machine Learning Scientist, Protein Engineering, Metagenomi<https://www.simplyhired.com/job/FHzAuigXayyBoo7RYld-yhnmzApistam8ckEjr38e-X…> * Product Development Engineer, Innovheart<https://www.innovheart.com/careers/> * Biomedical Senior System Engineer, i7<https://www.simplyhired.com/job/_AQK4-SqtqXjzL7Y3Qhis757glbpYANRD0sUuH2h8Z4…> * Bioengineer II, Cell and Gene Therapy R&D, Thermo Fisher Scientific<https://jobs.thermofisher.com/global/en/job/202160BR/Bioengineer-II-Cell-an…> * Quality Engineer, Merck Germany<https://jobs.vibrantm.com/job/Danvers-Quality-Engineer-Mass-01923/799960201…> * Biomechanical Engineer, ARCCA<https://www.simplyhired.com/job/6tJwmyn5R88bUCVhJ7inhRFAXgK3hK5AJnujC4LMFUv…> * Lab Manager, Merck<https://jobs.merck.com/us/en/job/MERCUSR176341ENUS/Lab-Manager?utm_source=i…> * Scientist, Catalent Cell & Gene Therapy<https://careers.catalent.com/us/en/job/CATAUS0067744EXTERNALENUS/Scientist?…> * Senior Product Development Engineer, Bioventus<https://jobs.jobvite.com/careers/bioventus/job/oVPujfwh?__jvst=Job%20Board&…> * Purdue Start-up Job Board<https://purduefoundry.com/jobs?utm_source=Foundry+Mailing+List&utm_campaign…>-Foundry Start Up Companies Looking to Hire * ACTS Career Center<https://careers.actscience.org/>-Association for Clinical and Translational Science * Doc Jobs<https://www.docjobs.com/jobs/list/>-Jobs beyond traditional clinical and academic roles Opportunity to Mentor Undergrads through GradTrack Below is an opportunity for graduate students to mentor undergraduates interested in pursuing graduate school. More information is available at: https://engineering.purdue.edu/Engr/Academics/Graduate/gradtrack/index_html. GradTrack Program Dates: Meet virtually on Monday nights in the Fall from 7-8:15pm for 1.5 hour from August 2022 - Dec 2022 (8 meetings total, dates to be shared soon; please see website for more information). There will also be a mandatory mentor training in August 2022 and a debrief dinner in early Dec 2022. Selected Graduate Student GradTrack Mentors will be given $1,000 for their time. What you will do as a mentor: * Receive mentorship training prior to program start. * Lead a group of 5-7 undergraduate students in monthly discussions about various topics related to graduate school (The Office of Graduate Education will share discussion topics). * Actively engage in mentoring. There will be an estimated 2-4 hours a month outside of the monthly meetings to answer student questions, meet one-on-one, and provide feedback on documents when appropriate. Eligibility criteria: * Be enrolled in a Master's or PhD program within Purdue's College of Engineering * Be in good academic standing with advisor support of your participation * Have an interest in mentoring underrepresented students Apply to be a GradTrack mentor here: https://purdue.ca1.qualtrics.com/jfe/form/SV_eM2h4IN5eWCLRjg<https://mx.technolutions.net/ss/c/MNF7HQcpApLpwULWGZBBFgnjQfhuXBMswcHottxTa…> To complete this application, you will need: A resume/CV, a screenshot confirmation email from your major professor/department confirming that they support you spending time as a mentor, and a short statement of interest in mentoring BIPOC undergraduate students. PCCR Monthly Series on Career Development: A Panel Discussion with Scientists from Eli Lilly: What an Industry Career Looks Like? See attached The next seminar in the Purdue Center for Cancer Research monthly series on career development will be April 28 from 11:30 AM - 12:30 PM. Jean Branttie, Madalyn Stancik, Maroun Beyrouthy and Stephanie Stout, from Eli Lilly and Company, will be presenting, "A Panel Discussion with Scientists from Eli Lilly: What an Industry Career Looks Like?" Please see the attached flyer for more details. Feel free to forward this invite to anyone you think would be interested. Register for this webinar at: https://purdue-edu.zoom.us/webinar/register/WN_EnOz9szFQfmyZYsTxtLT3Q After registering, you will receive a confirmation email containing information about joining the webinar. Check out other PCCR career development events and resources at: https://www.purdue.edu/cancer-research/Training%20and%20Education/Graduate%… If you have any questions or suggestions on the topics that could be covered in the career development series, please contact Jiang Yang at yang1491(a)purdue.edu<mailto:yang1491@purdue.edu>. PATHFINDER: A program dedicated to career development of Purdue life scientists Pathfinder is a new program dedicated to help with career development. Pathfinder aims to link with local companies and build bridges for improving the retention of talented life scientists in Indiana. The program exposes our talented graduate students and postdocs to scientists that are currently working in life sciences companies in Indiana and can act as models for successful careers at our doorsteps. The plan for the Pathfinder program is to conduct virtual interviews sessions with industry scientists and capture their story to identify factors for their success as industry scientists. Our first interview is with Jonathan Snyder, PhD, Principal Research Scientist at Elanco in Greenfield, IN: Thursday, April 28th from 3:30pm to 4:30pm. Join Zoom Meeting: https://purdue-edu.zoom.us/j/94020385466 [cid:image002.jpg@01D85AE1.12202E70] Graduate Professional Development Newsletter (April 22) https://mailimages.purdue.edu/vo/?FileID=6d154730-04ab-460e-aa6f-368f8ab63e… NEW! Exciting Program for Students in Regulatory Education https://contentsharing.net/actions/email_web_version.cfm?recipient_id=46418… System ID for Fall 2022 See attached Course announcement If you are interested in data science or any experimental work, please check this course. ME 584 deals with building models from data or the conditions that experiments must satisfy to extract the parameters of physical systems. The course will also give you some of the rigorous bases of AI/ML methods. You can contact course instructor Dr. Ariyur for questions. ME 584--System Identification Instructor: Kartik B. Ariyur (https://www.researchgate.net/profile/Kartik_Ariyur) Course description: The course this time will be suitable to students all around science and engineering and the data sciences. Students will be able to work on a variety of course projects identifying generalized least squares models, or dynamic system models, or various machine learning models. It will provide a fundamental grasp on the underlying theory (least squares, maximum likelihood estimation and connection to experiment design), models for estimation (ARMAX type or difference equation models, neural nets--supervised/unsupervised, physics-based), estimation algorithms (subspace, linear dimensionality reduction, convergence issues) and their implementation (testing for optimality, robustness, and statistical validity). Extensions to inverse problems and pattern recognition will also be covered. The course will possibly have an online section later on for those looking for schedule flexibility. The course has typically had students from all over engineering, including those from thermal and fluid sciences, food science, and agriculture. See the attached syllabus from last year for the details. Executive Functioning for Biomedical Researchers- May 2, 3 PM part of Mental Health Awareness Month May is Mental Health Awareness Month, and the NIH Office of Intramural Training and Education (OITE) is excited to be starting the month off with the fifth installment of the Mental Health and Well-being for Biomedical Researchers Series. Please join us May 2nd, 3:00-4:10pm ET for "Executive Functioning for Biomedical Researchers". The webinar will define executive functioning (EF) skills, with a particular focus on the role of EF for those working in biomedical research fields. The webinar will provide information on the types of daily stressors that impact one's executive functioning, as well as concrete ways to manage EF needs and build EF tools. Please Register<https://nih.zoomgov.com/webinar/register/WN_DkTSqof7Qd-VRAVMa2UDOQ>. Immediately following the webinar (from 4:10 - 5:10), we will host small group discussions facilitated by an OITE wellness advisor to discuss the material in greater depth. There will also be two supplemental sessions offered later in May, to further support EF skills building, as well as communicating about EF needs. Information on the follow-up sessions will be sent to those who register for the webinar. Additionally, a recording of the webinar will be made available 24-48 hours after the webinar. This series is open to everyone at NIH and beyond, so feel free to forward to colleagues at other institutions. NIH Career Symposium May 11-13, 2022 Registration is now open for the NIH Career Symposium (May 11-13, more info below) for all trainees in the biomedical sciences (intramural and extramural- postdocs and grad students). This year we are using an online platform to make it easier and to provide more interactions between participants and speakers. You are welcome to come to every session, or just the ones you are interested in. Registration is free (but please only register if you actually plan on coming) 1. The full agenda is Here<https://gcc02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwhova.com…> 2. See the Speakers<https://gcc02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwhova.com…> 3. Registration is here (the event is free). https://whova.com/portal/registration/multi2_202202/<https://gcc02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwhova.com…> Once registered we encourage you to explore the agenda and the current speakers-we are still adding more speakers in many sessions, so check back often! (and if you have a speaker request, let me know) ONE REQUEST-if you are planning to attend particular sessions please add that to your Agenda within the Whova pages-that way we have a feel for how many participants are coming to each session and if we have an adequate number of speakers. (instructions below) 15TH ANNUAL NIH CAREER SYMPOSIUM- AN ONLINE EVENT May 11-13, 2022 11:00 am - 5:45 pm The NIH Career Symposium highlights the diversity of career choices available to biomedical researchers today. Whether you are a new graduate student, postdoc, or clinical fellow just beginning to consider career options or a senior student/fellow ready to look for a job, the NIH Career Symposium is for you. Wondering what the Career Symposium is all about? Check out past events here<https://www.training.nih.gov/nih_career_symposium>. We have already recruited over 250 speakers for you to network with. We will start each day with an intro on each sector (career options, being a competitive applicant, resources for success. This is a great way for you to jumpstart each day and plan for what events you would like to attend. Then you will have the ability to network with professionals in a variety of jobs, participating in informational interviews, which we hope will help you identify your career of choice and the steps required to get your foot in the door. We will host a series of zoom rooms for career conversations with one or two speakers. Multiple rooms with speakers in similar career paths will run concurrently. For example, research positions in industry would have multiple rooms going at once. Our goal is that each room will have no more than 15 participants, giving every attendee ample time to connect with a professional. Participants will have the ability to move through the "rooms" as they like, meeting a speaker, asking questions, or even just listening in to see if a particular career path looks enticing. NOTE: What is said in these rooms will NOT be recorded. We will also have a workshop on Why Career Choices are so Hard: a practical guide for navigating the career on Wednesday afternoon, and a workshop on Thursday afternoon on Current Hiring Trends. Closer to the event we will send a guide to those registered on how to navigate these rooms for informational interviews (including seed questions). WED-MAY-11 - ACADEMIC CAREERS * 11:00am-11:50am - Seminar: Introduction to Academia (will be recorded) * 12:00pm-1:00pm - Research Intensive Faculty * 1:10pm 2:10pm - Teaching Intensive Faculty * 2:20pm-3:20pm - Non-Faculty Research (Academics) (like core directors, staff scientists, etc) * 3:30pm-4:30pm - Supporting Academic Science (postdoc office, grants, student services, program support, admin) * 4:40pm -5:40pm- Seminar: Why Career Choices are so Hard: a practical guide for navigating the career process (will be recorded) THU-MAY-12 - INDUSTRY CAREERS * 11:00am-11:50am - Seminar: Industry overview (will be recorded) * 12:00pm-1:00pm - Industry- Bench Careers * 1:10pm 2:10pm - Industry: Nonbench Careers (MSL, FAS, sales, marketing, reg affairs, etc) * 2:20pm-3:20pm - Business, Technology Transfer and Patent Careers (law, consulting, PTO, business Development, Tech Transfer) * 3:30pm-4:30pm - Public Health/Clinical * 4:40pm -5:40pm- Seminar: Current Hiring Trends (will be recorded) FRI-MAY-13 - FOR THE LOVE OF SCIENCE CAREERS * 11:00am-11:50am - Seminar: Introductions to today's careers (will be recorded) * 12:00pm-1:00pm - Science Policy * 1:10pm 2:10pm - Careers in Science Communication (editors, science writing, etc) * 2:20pm-3:20pm - Government Careers (mostly non-bench, all branches) * 3:30pm-4:30pm - Science Education and Outreach Careers / Data Science / Non-Profits If you would like to explore these career options on your own schedule, we have a plethora of panels, interviews and written synopses of previous events. Check out past events here<https://www.training.nih.gov/nih_career_symposium>. Instructions for WHOVA Agenda ADD https://whova.com/embedded/event/multi2_202202/?utc_source=ems<https://gcc02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwhova.com…> 1. Find the Agenda tab on the side of the screen. You should see a list of sessions for that day. 2. You can move through different days by selecting the date you want to view on the calendar at the top of the agenda 3. Browse or search for sessions on the top bar. 4. Once you find the session you want to access, tap on it. 5. If the session is live, it will begin playing immediately upon entering. Otherwise, a message will indicate the scheduled start time. 6. If the session hasn't occurred yet, you can click Add to My Agenda to put the session on your own personal agenda. Fall 2022 Tech Commercialization and Entrepreneurship Course See attached flyer Featured Database: Web of Science Focus Web of Science provides access to the world's leading scholarly literature in the science, social sciences, arts, and humanities and examine proceedings of international conferences, symposia, seminars, colloquia, workshops, and conventions. Access The List of Business Databases<http://guides.lib.purdue.edu/az.php?s=71213%20> is the alphabetical list of the databases specially selected for those in a business program of study. Access the databases off-campus with your Purdue Career Account. Tutorial Click Getting Started with Web of Science<https://youtu.be/2qoj1gXAPNo> to see the basics of using this database. Related Resources Some other resources you might want to explore are: * Business Source Complete<https://go.lib.purdue.edu/db/db141>, indexes and abstract articles in business management, marketing, MIS, accounting, finance, international business, and related disciplines. * EconLit<https://go.lib.purdue.edu/db/econlit>, provides access to bibliographic citations, journal articles, books, dissertations, and more in the areas of economic development, forecasting, and history; fiscal and monetary theory; and more. Workshops and Deadlines Here are some upcoming workshops and deadlines more detailed information about the workshops will be sent out separately closer to the event. April 29th Deadline to apply for summer Intensive Writing Experience (IWE) April 30th Bloomberg Data Science Fellowship Due<https://www.techatbloomberg.com/bloomberg-data-science-ph-d-fellowship/> May 4th OIGP Spring Reception May 5th Faculty Coffee Chat: Professor Alexandria Volkening May 13th Peer Mentoring Grab and Go Lunch News from You Please inform Tammy of honors, awards, or other accolades (to include having a paper published) you receive so that the Weldon School may recognize your accomplishments. Send the complete information - specific title and nature of the award, name of conference or event at which award was given, date of said event, photograph if available, etc. - to tsiemers(a)purdue.edu<mailto:tsiemers@purdue.edu>. Tammy Siemers Senior Graduate Training Program Administration and Professional Development Specialist Weldon School of Biomedical Engineering 206 S. Martin Jischke Drive, West Lafayette, IN 47907-2032 o: 765-496-0294 Achiever, Relator, Includer, Restorative, Developer [233FFCD4]<https://www.purdue.edu/?utm_source=signature&utm_medium=email&utm_campaign=…>

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BME PhD Preliminary Exam Announcement for Karl Ferdinand Ziegler (S. Iyer-Biswas, advisor)
by May, Sandra M 25 Apr '22

25 Apr '22

BME PhD Preliminary Exam Announcement for Karl Ferdinand Ziegler (S. Iyer-Biswas, advisor) Title: Precision measurements and long-term live imaging of stochastic dynamics of whole organisms Everyone is invited to attend the public presentation beginning at 10:00 AM ET. Date: May 5, 2022 Time: 10:00 AM ET Location: Zoom - Time: May 5, 2022 10:00 AM ET https://purdue-edu.zoom.us/j/91596296472 Meeting ID: 915 9629 6472 Passcode: 059756 Advisory Committee: Srividya Iyer-Biswas; Dana Weinstein; Rudro R. Biswas; Young Kim Abstract: Over 150 years since Claude Bernard coined the evocative phrase, "milieu intérieur", to draw attention to a deep mystery in the natural world, fundamental questions remain open about how the simplest living system, a bacterial cell, maintains homeostasis of its best studied attribute, cell size. In this preliminary work towards dissertation, I will address how life shapes time in a bacterial cell, and discuss the interplay between homeostasis and adaptation in this context. First, I will first establish that stochastic intergenerational bacterial cell size homeostasis is maintained under constant growth conditions for non interacting cells, using our high-precision data on growth and division of individual C. crescentus cells using our SChemostat technology. Next, the emergent simplicities or scaling laws revealed by these data, and their mechanistic implications. Following this, the questions, approaches and challenges in the extension to time-varying growth conditions, other microorganisms, and spatially patterned arrangement of cells, and possible new emergent simplicities.

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[Bmeroundtable-list] BME Monday Roundtable - April 25, 2022
by Gelfand, Johanna K 25 Apr '22

25 Apr '22

[cid:image001.png@01D858A7.34996340] BME MONDAY ROUNDTABLE April 25, 2022 HEAD UPDATE Hello everyone, As we approach the end of semester- we have a lot of exciting opportunities to connect, look at future research opportunities, and celebrate accomplishments. Specifically, this week Wednesday we will have an Engineering Solutions in Pediatric Healthcare Symposium from 1:00-4:30 PM. Thursday, we will have a Faculty Mentor Award Celebration from 12pm to 1pm sponsored by BMEGSA for faculty, staff, and grad students. And Friday, an end-of-semester informal celebration for the Weldon School students, faculty and staff will be held at the MJIS South Lawn, from 3 - 5 pm. I look forward to seeing you all at these events this week! PROTECT PURDUE * Masks protocols changed as of March 14! Check for updates https://protect.purdue.edu/required-covid-19-protocols/ * Vaccines are strongly encouraged (though not required) https://protect.purdue.edu/vaccine-information/ * Updated guidance for research SOPs, etc. and Protect Purdue are coming quickly. Please make sure you are staying current with Purdue guidelines. UPCOMING IMPORTANT DATES Week of April 25 Tues., April 26 - BRAG Session, 12:00 p.m., MJIS 2001, Dr. Young Kim, Associate Head for Research and Associate Professor of Biomedical Engineering, "The good, the bad, and the ugly of clinical research as a biomedical engineering." Tues., April 26 - BME PhD Preliminary Exam Announcement for Jordanna Payne (L. Solorio advisor), 3:00 p.m., BRK 1001. Title: Development and characterization of a subcutaneous porcine ex-vivo tissue culture model. Please note this prelim is open only to those who have signed the Lilly NDA. Wed., April 27 - Purdue Day of Giving 20.22 Relay Run. Cheer on one of our very own, Leony Boudreau, as she joins with others from the College of Engineering in a Relay Run. Her check-in time is 11:05 AM; run time is 11:20 AM. 13 Boilermakers (student leaders, faculty, staff, and alumni) will run a relay (some participants will run concurrently) totaling 20.22 miles. The route loops around campus and passes four Engineering facilities that we are highlighting this year. See attached route map. You can find more information about the event, the runners, and giving opportunities in Engineering that we are highlighting here: https://engineering.purdue.edu/Engr/DayofGiving We invite everyone to join us for a celebration as the final runners cross the finish line. We will gather at the Gateway Arch at the corner of Stadium Ave. and University St. at around 1:45 p.m. on April 27; we expect the final runners to cross around 2:00 p.m. We will have cookies and for those who show they made a gift on Day of Giving, a fun pair of branded socks (while supplies last)-back by popular demand! Wed., April 27 - Weldon School of Biomedical Engineering Distinguished Seminar Series, 9:30 a.m., MJIS 1001 or Via Zoom: https://purdue-edu.zoom.us/j/95150439811?pwd=a3hOK0o0bmpkS3poTVBCbVhDNU9FZz… Maria Soledad Sosa, Assistant Professor of Pharmacological Sciences at Mount Sinai Hospital will present "Origins and Behavior of Disseminated Tumor Cells During Minimal Residual Disease." NOTE: Although this seminar will be presented virtually, BME 690 students are still expected to attend in person in MJIS 1001. Wed., April 27 - Engineering Solutions in Pediatric Healthcare, 1:00-4:30 p.m., MJIS 2001 and via Zoom. Join us on April 27 to discuss the intersection of engineering and medicine in pediatric healthcare. Hear from faculty and clinicians from Purdue's Weldon School of Biomedical Engineering, Indiana University School of Medicine, Riley Children's Hospital and industry experts from Cook Medical. Wed., April 27 - BME PhD Preliminary Exam Announcement for Angel G. Enriquez (H. Lee, advisor), 3:00 p.m., MRGN 129. Title of presentation: Magnetic actuators for smart functionality in biomedical devices. Thurs., April 28 - Seminars in Research Hearing at Purdue, 10:30-11:20 via Zoom. Jasmine Kwasa, PhD, Post-doctoral Fellow at the Neuroscience Institute at Carnegie-Mellon University will speak on "Developing equitable neurotechnologies and addressing racial and phenotypic bias in human neuroscience methods." Zoom link: https://purdue-edu.zoom.us/j/93108158900?pwd=RDdTQ0Z4UE9Rb0JUenhjMG1SMkp2QT… Thurs., April 28 - Faculty Mentor Award Celebration (sponsored by BMEGSA). Lunch social to celebrate awardees Dr. Vitaliy Rayz (2020), Dr. Joseph Rispoli (2021) and Dr. Dianne Little (2022). 12pm - 1 pm, MJIS Lawn (MJIS 2001 rain location). Faculty, staff and graduate students are welcome! Thurs., April 28-Fri., Apr. 29: Vanderbilt University will be hosting the annual Vanderbilt Integrative Training Alliance (VITA) Symposium, a conference focused on biomedical sciences graduate students. Attendees have a unique opportunity to connect with the Vanderbilt community, obtain a long-term mentoring relationship with a Vanderbilt faculty member, and gain training in scientific communication. The event will also feature a keynote address from Vanderbilt postdoc alumna, Dr. Shaneda Anderson<https://urldefense.com/v3/__https:/nam04.safelinks.protection.outlook.com/?…>. This year the conference will be virtual. Details below. Fri., April 29 - End-of-semester celebration for the Weldon School students, faculty and staff. MJIS South Lawn on Friday, April 29, 3 - 5 pm. This informal event will include student awards announcements and elected BMES leadership introductions as well as yard games and fun. Light refreshments and drinks will be provided. Please join us on Friday afternoon! Sun., May 1 - Nominations due from ALL faculty for graduate TA positions. See academic programs update for specifics. Upcoming important deadlines and info. Thurs., May 5: Coffee Chat with Faculty: 11:00 am -12:00 pm, Location LYLE (Room TBM). Faculty host: Alexandria Volkening. Potential discussion topics: website development, public science and outreach, social media, academic job materials (with an interdisciplinary perspective) Sun., May 15: Deadline for applications for Bioengineering Training in Diabetes Research Program (T32 Predoctoral Fellowships). See below for details. Tues., May 31: Deadline for submission of abstracts for BMES 2022 Annual Meeting, to be held October 12-15 in San Antonio, TX. For more information: https://www.bmes.org/abstract-information This year's meeting theme is "Embracing Inclusion to Advance Innovation in Healthcare and Education" Fri., June 3: Application deadline for Trailblazers in Engineering program. See below for details. Committee Updates Academic Programs Update Undergraduate TAs have been an invaluable resource for many BME courses this year and we hope to continue working with them in the future. Please identify and reach out individually to any undergraduates that you think would be exceptional undergraduate TAs for your course and have them complete this survey: https://purdue.ca1.qualtrics.com/jfe/form/SV_5dRAV4R9XqKCntk. We will review submissions over the next month and send out details for instructors to invite those that applied to become UGTAs for the upcoming academic year. Please encourage students to apply as soon as possible since the end of the semester is quickly approaching. [cid:image002.jpg@01D858A7.34996340] ALSO: If you have graduate students in your lab who may be interested in serving as a TA this coming year, we need your nominations (including their additional background information) by May 1st, 2022. If your student has a fellowship for the upcoming academic year, we ask that you please refrain from nominating them at this time. In the Weldon School we do our best to distribute teaching assignments to the students who are the best fit for each course. Therefore, if you have any graduate students (residents or international) who you would like to be considered for a TA appointment in the 2022-2023 year, please complete the following survey with the required information for determining best fit: https://purdue.ca1.qualtrics.com/jfe/form/SV_bE3cqxEqECAvDVQ A description of courses is attached for your reference. If you are nominating an international student who has not taken the Oral English Proficiency Test (OEPT), please contact Asem Aboelzahab (aboelzahab(a)purdue.edu<mailto:aboelzahab@purdue.edu>) to schedule your student for the test ASAP (May 7th at the latest). Upcoming test dates will be in June/July. All international students must complete and pass an Oral English Proficiency Test (OEPT) before being certified for a TA assignment. The test does not expire, so a student remains certified for the duration of their position at Purdue. Note that preference will be given to students in the graduate programs of the Weldon School. Graduate Committee Programs Update Update on Weldon Grad-Program Update Process: * Based on all the input and feedback we have received and our discussions throughout the year, we have developed thorough DRAFT outline documents for the new Qualifying Exam process and the revised Prelim Exam process. * Each document describes the Rationale, Expectations, Logistics/Process, and Resources associated with each process, and are intended to inform everyone so that both students and faculty understand the process and rationale. * Each new process was developed based on the themes that emerged from input and feedback we received, e.g., * consistent and broad mentoring from start to finish, * flexibility in milestone timing given the diversity of entering students' experience and backgrounds, * a need for more formal writing courses, * a desire to have milestone processes be useful for the student and not just busy work for students to complete and faculty to evaluate * consistent and well-communicated rigorous expectations for advancement to each stage of the PhD Training Program * We have spent one entire Grad-Committee meeting discussing the qual document and another meeting discussing the prelim document to fine tune our plans. * We are now voting to make sure all committee members are comfortable with the details of the new frameworks we have developed. * Once formally approved by the Grad Committee (next two weeks), we will be distributing these documents as well as sharing a report on the feedback we received and how it was incorporated into our plans. We will also be fine-tuning the processes (e.g., developing rubrics and registration forms to ensure smooth implementation of these new processes. * Note: these new processes will be implemented this Fall (2022) for all incoming students. Current students will have the option (individually) to use the old or new system depending on what is best for them. * Thank you again for your support and input/feedback on this important process!! BME Graduate Committee DEI Committee Update Thank you to everyone that came out to the Open Forum this semester. A document that summarizes the meeting minutes is available to those that were not able to attend (attached). With the goal of fostering an inclusive BME culture and enhancing our undergraduate curriculum, BMES aims to bring our students and faculty closer together by hosting more Undergraduate Open Forums in future semesters. We hope to see you there! Remaining BME Graduate Peer Mentoring meeting days are: 11-1pm on May 13th Trailblazers in Engineering (TBE) are workshops to prepare future trailblazing faculty in engineering with a focus on preparing outstanding scholars who are also committed to increasing the success of underrepresented communities of engineers. Fellows will network with leading faculty in engineering, thought leaders, program managers at key federal funding agencies, Purdue Engineering heads, and of course, each other. Participants will also meet current Trailblazers and benefit from their inspiring keynote talks. TBE 2022 will be held in person on Purdue's beautiful West Lafayette, IN campus July 26 - 28, 2022. More information and application details for the Black Trailblazers in Engineering (BTE) and Latinx Trailblazers in Engineering (LATinE) program is available at: https://engineering.purdue.edu/Engr/Trailblazers APPLICATION DEADLINE: June 3, 2022 Resources, attachments, further information BRAG Session, Tues., April 26, 12:00 p.m., MJIS 2001, Dr. Young Kim, Associate Head for Research and Associate Professor of Biomedical Engineering, "The good, the bad, and the ugly of clinical research as a biomedical engineering." Dr Kim writes that he will share multiple failures and a couple of happy stories. Spread the word - bring another postdoc! BME PhD Preliminary Exam Announcement for Jordanna Payne (L. Solorio advisor), Tues., April 26, 3:00 p.m., BRK 1001. Title: Development and characterization of a subcutaneous porcine ex-vivo tissue culture model. Please note this prelim is open only to those who have signed the Lilly NDA. Advisory Committee: Luis Solorio, Chair; Douglas Brubaker; Sherry L. Harbin; Michael Wendt Abstract: The subcutaneous route of drug delivery is desirable due to patient comfort and ease of administration. One of the biggest challenges in studying drug delivery in the subcutaneous space is the lack of in-depth knowledge about the composition of the space. Because of this, several drugs encounter difficulty being delivered via this route presenting challenges during clinical trials. Currently, drugs are tested in vitro and in vivo. In vitro experiments are more cost effective but lack the ability to provide information about drug uptake by tissue and other interactions or toxicities. In vivo experiments can provide this information but are costly. There is a need for a platform that can be used to study subcutaneous injection of drugs ex-vivo. This work details the development and validation of a model of ex-vivo subcutaneous porcine tissue culture for up to one week utilizing three distinct anatomical locations from Yucatan mini pigs. Tissue specimens of 12mm in diameter from behind the ear, the breast, and the belly were cultured for seven days with average viability greater than 85%. Next, Liquid Chromatography-Mass Spectrometry (LC-MS) was utilized to track changes in the subcutaneous proteome as a result of time in culture. Next, LC-MS will be utilized to track changes in the subcutaneous proteome of a commercially available ex-vivo human tissue model to compare to the porcine model. Finally, parameters for scaling of the model for high throughput will be determined. Raising A Resilient Scientist Workshop Series (Message from Sharon Milgram, Director, NIH Office of Intramural Training & Education): Over the last year I have interacted with many trainees across the U.S. as part of the NIH Becoming a Resilient Scientist series<https://www.training.nih.gov/nih_becoming_a_resilient_scientist_series>. After carefully considering input from students, postdocs, faculty and program administrators who participated in the program, I have decided to offer a series, RAISING A RESILIENT SCIENTIST<https://www.training.nih.gov/workshops_and_trainings_for_extramural_princip…>, for faculty and administrators who mentor students and postdoctoral fellows in the biomedical, behavioral, and social sciences. The goal of the Raising a Resilient Scientist series is to promote the mental health and well-being of the academic research community by supporting faculty and administrators to develop self-management, relationship-management, and mentoring skills. A variety of topics will be covered with a specific focus on communication and shared problem-solving to help trainees deal with the inevitable setbacks experienced in high knowledge environments. There will be five units in the series; each unit will consist of a 75-minute lecture, which can be watched in real-time or asynchronously, followed by a 1-hour facilitated discussion with peers. There will be two opportunities for participation in the small groups following each webinar. There is no charge for participation, but advanced registration is required. For more information, and to register, please visit our webpage<https://www.training.nih.gov/workshops_and_trainings_for_extramural_princip…>. I do not anticipate offering this series again in the future; participation in the entire series is recommended but is not required. Please do not hesitate to email me if you have any questions. Current scheduled workshop dates are April 26 and May 24. Engineering Solutions in Pediatric Healthcare, Wed., April 27, 1:00-4:30 p.m., MJIS 2001 and via Zoom. Join us on April 27 to discuss the intersection of engineering and medicine in pediatric healthcare. Hear from faculty and clinicians from Purdue'sWeldon School of Biomedical Engineering, Indiana University School of Medicine, Riley Children's Hospital and industry experts from Cook Medical. Topics include: * History of biomedical engineering and pediatrics research at Purdue * What research is going on now to treat pediatric disease * Discuss how we can increase collaborative opportunities and overcome challenges in the development and translation of pediatric medical devices Registration is encouraged by April 18. For more information and to register for the event, visit: purdue.link/2022-pediatric-symposium Weldon School of Biomedical Engineering Distinguished Seminar Series, Wed., April 27, 9:30 a.m., MJIS 1001 or Via Zoom: https://purdue-edu.zoom.us/j/95150439811?pwd=a3hOK0o0bmpkS3poTVBCbVhDNU9FZz… Maria Soledad Sosa, Assistant Professor of Pharmacological Sciences at Mount Sinai Hospital will present "Origins and Behavior of Disseminated Tumor Cells During Minimal Residual Disease." NOTE: Although this seminar will be presented virtually, BME 690 students are still expected to attend in person in MJIS 1001. Abstract: Metastatic disease is the leading cause of cancer related mortality across a variety of tumors. Disseminated tumor cells (DTCs) are considered the source of metastasis and they remain in a reversible non-proliferative state of dormancy resisting anti-proliferative therapies during the extended and asymptomatic periods of the minimal residual disease. Expanding our knowledge on how DTCs survive in a dormant state in their new microenvironments, how DTCs interact with the immune system, what are the signals that trigger their reactivation programs, and what are the signals responsible for long-term dormancy, may likely improve predicting patient survival rates and increase the opportunities to design therapies that will extend the remission phase. Bio: Dr. Sosa did her career in Molecular Biology at the University of San Luis, Argentina and her undergraduate training at Leloir Institute in Argentina under the supervision of Drs. Llera and Podhajcer, where she studied the secretome of melanoma cancer. In 2005, Dr. Sosa started her Ph.D. training in Dr. Marcelo Kazanietz's laboratory at the University of Pennsylvania (UPENN). During her training she focused on the mechanisms of action of Rac-GEFs and -GAPs in breast cancer. In 2010, Dr. Sosa joined Dr. Aguirre-Ghiso's lab as a postdoctoral fellow at Mount Sinai Hospital. Since then, Dr. Sosa has focused on the study of minimal residual disease in an attempt to understand the mechanistic pathways in disseminated tumor cells (DTCs). In 2017, Dr. Sosa started an Assistant Professor appointment in the Department of Pharmacological Sciences at Mount Sinai Hospital. Dr. Sosa has published more than 25 articles and has secured several grants including: Schneider-Lesser Foundation Fellow Award, CSBC Pilot Project-Sage Bionetworks, Melanoma Research Alliance Team Science Award (Co-PI), NCI-K22, CCR Basic/Translational and Clinical Susan Komen, Melanoma Research Foundation, Breast Cancer Foundation, and The Mark Foundation (Co-PI) grants. Her lab research focuses on providing new biomarkers and treatments derived from the novel biology of dormant disease to manage minimal residual disease and prevent metastasis. ~BME Faculty Host: Dr. Luis Solorio ~ BME PhD Preliminary Exam Announcement for Angel G. Enriquez (H. Lee, advisor), Wed., April 27, 3:00 p.m., MRGN 129. Title of presentation: Magnetic actuators for smart functionality in biomedical devices. Advisory Committee: Hyowon Lee, Chair; Chi Hwan Lee; Luis Solorio; Daniel H. Sahlein Abstract: Magnetism provides numerous advantages to actuating systems, specifically for biomedical applications. The untethered transfer of energy and scalability of magnetic actuators enables functionality to an otherwise passive system. For example, the wireless magnetic actuation can turn static 2D and 3D cell cultures into a more physiologically-relevant dynamic environment while limiting contamination. Moreover, indwelling catheters and implantable sensors are typically stationary devices that are notorious for their short lifespan when implanting into the body due to immune responses. Magnetic microactuators may be used for wireless actuation for in situ removal of biological materials accumulated on chronically implanted devices. In this dissertation, I will demonstrate examples of novel biomedical microdevices enabled by magnetic actuation for added functional benefits. First, I will describe a soft polymer magnetic actuator that can facilitate the study of a physiologically relevant cell culturing system. By cyclically stretching an extracellular matrix protein in a 3D cell culture, this system can elucidate the process by which breast cancer cells respond to a dynamic environment in the lungs. The fibrillar fibronectin suspended across the body of the magnetic actuator provides a matrix representative of early metastasis for 3D cell culture that has not yet been recapitulated in vitro until now. Our findings suggest that this dynamic environment leads to significant matrix degradation in breast cancer cell lines with metastatic potential. Our results demonstrate a clear suppressive cellular response due to cyclic stretching that has implications for a mechanical role in the dormancy and reactivation of disseminated breast cancer cells to macrometastases. As a second application, I will demonstrate the use of magnetic microactuators to remove biofouling on an implantable biosensor in order to prolong its functionality. The results of our work suggest that the motion of the actuator on the sensor surface can maintain biosensor signal integrity and prevents the downstream effects of the foreign body response. In the future, I plan to evaluate the performance of the self-clearing biosensor in vivo to demonstrate chronic and reliable sensor functionality. Seminars in Research Hearing at Purdue, Thurs., April 28, 10:30-11:20 via Zoom. Jasmine Kwasa, PhD, Post-doctoral Fellow at the Neuroscience Institute at Carnegie-Mellon University will speak on "Developing equitable neurotechnologies and addressing racial and phenotypic bias in human neuroscience methods." Zoom link: https://purdue-edu.zoom.us/j/93108158900?pwd=RDdTQ0Z4UE9Rb0JUenhjMG1SMkp2QT… Bio: Jasmine Kwasa, PhD, is an NIH-funded post-doctoral fellow in the Neuroscience Institute at Carnegie Mellon University (CMU). Originally from the South Side of Chicago, Jasmine earned her B.S. from Washington University in St. Louis, her M.S. from Boston University (both in Biomedical Engineering), and her Ph.D. in Electrical and Computer Engineering from CMU. Her ongoing post-doctoral research seeks to develop neurotechnologies, such as EEG and fNIRS, optimized for coarse, curly hair and dark skin pigmentation with collaborators at CMU. She is also a neuro-ethicist and writes about the future of inclusive neurotech and the history of racial bias in neuroscience, medicine, and technology. Jasmine has received several honors throughout her training, including being named a Ford Foundation Fellow, an NSF Graduate Research Fellow, a Society for Neuroscience fellow, and a "Rising Star in Biomedical Sciences" by MIT. In her free time, Jasmine is a dance fitness instructor and enjoys travel and time with her enormous family. This seminar is presented in conjunction with Purdue Speech, Language, and Hearing Sciences (SLHS) Diversity, Equity and Inclusion Committee, and the Purdue Institute for Integrative Neuroscience (PIIN). Vanderbilt Integrative Training Alliance (VITA) Symposium, April 28-29: On April 28-29th, Vanderbilt University will be hosting the annual Vanderbilt Integrative Training Alliance (VITA) Symposium, a conference focused on biomedical sciences graduate students. Attendees have a unique opportunity to connect with the Vanderbilt community, obtain a long-term mentoring relationship with a Vanderbilt faculty member, and gain training in scientific communication. The event will also feature a keynote address from Vanderbilt postdoc alumna, Dr. Shaneda Anderson<https://urldefense.com/v3/__https:/nam04.safelinks.protection.outlook.com/?…>. This year the conference will be virtual. The complete two day schedule can be found here<https://urldefense.com/v3/__https:/nam04.safelinks.protection.outlook.com/?…>. While the symposium is open to all, we particularly encourage individuals from backgrounds underrepresented in academia to apply, including but not limited to those who identify as Black, African-American, Latino, Hispanic, Native American, or Pacific Islander, those who have a disability, first generation college-goers, those from disadvantaged socio-economic backgrounds, and those underrepresented on the basis of gender identity or expression or sexual orientation. I am hoping that we will have representation from every Big 10 school (University of Illinois, Indiana University, University of Iowa, University of Maryland, University of Michigan, Michigan State University, University of Minnesota, University of Nebraska-Lincoln, Northwestern University, Ohio State University, Pennsylvania State University, Purdue University, Rutgers University-New Brunswick, and the University of Wisconsin-Madison). Do you know of any students who would be interested in applying? If so, please respond to antentor.o.hinton.jr(a)Vanderbilt.Edu<mailto:antentor.o.hinton.jr@Vanderbilt.Edu> with their name and email and a member of our team will reach out. Thank you for your consideration, Antentor Othrell Hinton, Jr., Ph.D. Pronouns: He/Him/His Twitter: @phdgprotein86 LinkedIn: https://www.linkedin.com/in/biogeek26/<https://urldefense.com/v3/__https:/www.linkedin.com/in/biogeek26/__;!!DZ3fj…> Lab Twitter: @AtHinton EE Just Faculty Scholar (UNCF award) Assistant Professor Department of Molecular Physiology and Biophysics Vanderbilt School of Medicine Basic Sciences The Vanderbilt Diabetes Research and Training Center Poster Submission Application and Details<https://www.purdue.edu/gradschool/oigp/events/spring-reception/submission.h…> Award Application and Details<https://www.purdue.edu/gradschool/oigp/events/spring-reception/award-applic…> Deadline for applications for Bioengineering Training in Diabetes Research Program (T32 Predoctoral Fellowships), Sun., May 15. Eligibility: * U.S. Citizen or Permanent Resident * Admission to Purdue BME PhD, Purdue IBSC PhD, or Indiana MSTP MD/PhD Programs * Project scope relevant to NIDDK high-priority areas, including diabetes & other metabolic diseases, obesity, digestive diseases, nutrition, gut microbiome, role of nervous system in GI health, kidney & urologic diseases, etc. * 1-2 page proposal, including: Name, Matriculation pathway (BME, IBSC, MSTP), proposed faculty co-mentors, proposed research project, signed letter of support from faculty co-mentors (not included in 2-page limit). Note: Applicants should work with faculty trainers when completing application proposal; Fellowship funding period: 9/4/2022-9/3/2023 Directors: Sherry Harbin, PhD and Carmella Evans-Molina, MD, PhD Administrators: Sandy May and Tammy Siemers. For more information, please contact: WeldonBMEGrad(a)purdue.edu<mailto:WeldonBMEGrad@purdue.edu> (phone: 765-494-7054) or visit online at http://bit.ly/Purdue-IUSM-BTDR Trailblazers in Engineering (TBE) are workshops to prepare future trailblazing faculty in engineering with a focus on preparing outstanding scholars who are also committed to increasing the success of underrepresented communities of engineers. Trailblazers in Engineering Fellows are selected not only for their outstanding scholarly achievements but also for their potential impact in expanding representation and diversity in engineering. The workshop will provide Fellows the ability to network with leading faculty in engineering, thought leaders, program managers at key federal funding agencies, Purdue Engineering heads, and of course, each other. Participants will also meet current Trailblazers and benefit from their inspiring keynote talks. TBE 2022 will be held in person on Purdue's beautiful West Lafayette, IN campus July 26 - 28, 2022. APPLICATION DEADLINE: June 3, 2022 Reasons to Attend 1. Network with leading trailblazing faculty in engineering, thought leaders, program managers at key federal funding agencies, Purdue Engineering heads, and scientists who will present keynote speeches and talks throughout the program. 2. Gain insight into what academic success will look like post-pandemic. 3. Participate in panel discussions. * Why choose an academic career? * How to apply & interview? * How to negotiate salary and start-up packages? * How to get early career research funding? 4. Meet program managers from the National Science Foundation, Office of Naval Research, Air Force Office of Scientific Research, National Institutes of Health and others; receive advice on your proposals; and participate in a poster session to pitch your research and teaching plans and get feedback from would-be employers. 5. Attend the "Success Strategies for New Faculty Members" workshop presented by internationally recognized experts in faculty development, Drs. Richard Felder and Rebecca Brent. 6. For non-Purdue Fellows, we are reimbursing up to $800.00 per Economy flight and transportation (cab fare, shuttle, mileage, and/or parking to/from Purdue). In addition, we will provide two days of per diem for travel days of July 25 & 28. APPLICATION DEADLINE: June 3, 2022 Applicants are invited to apply through two programs, Black Trailblazers in Engineering (BTE)<https://maillinks.purdue.edu/t/42895178/1487133596/88073767/0/120588/?f5d63…> and Latinx Trailblazers in Engineering (LATinE)<https://maillinks.purdue.edu/t/42895178/1487133596/88073768/0/120588/?f5d63…>. Please visit these pages for details. Attachments BME Course Descriptions SpringUndergraduateOpenForum-Minutes PDOG-RunMap-Flyer -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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FW: Student Group Leaders for Purdue Day of Giving
by Siemers, Tammy R 21 Apr '22

21 Apr '22

Hello All, Brian Knoy (copied) in our development office is looking for a few grad students to hand out doughnuts on Purdue Day of Giving on April 27 from 9-11:00 in MJIS atrium. Please let him know if you are interested in helping out. Tammy

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[Bmeroundtable-list] BME Distinguished Seminar Series - Wednesday, April 27
by Gelfand, Johanna K 21 Apr '22

21 Apr '22

[cid:image001.jpg@01D85588.9711F7C0] Weldon School of Biomedical Engineering Distinguished Seminar Series Wednesday, April 27, 2022 9:30-10:20am MJIS 1001 or Via Zoom: https://purdue-edu.zoom.us/j/95150439811?pwd=a3hOK0o0bmpkS3poTVBCbVhDNU9FZz… This seminar will be presented virtually. BME 690 students are still expected to attend in person. Origins and Behavior of Disseminated Tumor Cells During Minimal Residual Disease [cid:image002.jpg@01D85588.9711F7C0] Maria Soledad Sosa, Ph.D. Assistant Professor Department of Pharmacological Sciences Mount Sinai Hospital Abstract: Metastatic disease is the leading cause of cancer related mortality across a variety of tumors. Disseminated tumor cells (DTCs) are considered the source of metastasis and they remain in a reversible non-proliferative state of dormancy resisting anti-proliferative therapies during the extended and asymptomatic periods of the minimal residual disease. Expanding our knowledge on how DTCs survive in a dormant state in their new microenvironments, how DTCs interact with the immune system, what are the signals that trigger their reactivation programs, and what are the signals responsible for long-term dormancy, may likely improve predicting patient survival rates and increase the opportunities to design therapies that will extend the remission phase. Bio: Dr. Sosa did her career in Molecular Biology at the University of San Luis, Argentina and her undergraduate training at Leloir Institute in Argentina under the supervision of Drs. Llera and Podhajcer, where she studied the secretome of melanoma cancer. In 2005, Dr. Sosa started her Ph.D. training in Dr. Marcelo Kazanietz's laboratory at the University of Pennsylvania (UPENN). During her training she focused on the mechanisms of action of Rac-GEFs and -GAPs in breast cancer. In 2010, Dr. Sosa joined Dr. Aguirre-Ghiso's lab as a postdoctoral fellow at Mount Sinai Hospital. Since then, Dr. Sosa has focused on the study of minimal residual disease in an attempt to understand the mechanistic pathways in disseminated tumor cells (DTCs). In 2017, Dr. Sosa started an Assistant Professor appointment in the Department of Pharmacological Sciences at Mount Sinai Hospital. Dr. Sosa has published more than 25 articles and has secured several grants including: Schneider-Lesser Foundation Fellow Award, CSBC Pilot Project-Sage Bionetworks, Melanoma Research Alliance Team Science Award (Co-PI), NCI-K22, CCR Basic/Translational and Clinical Susan Komen, Melanoma Research Foundation, Breast Cancer Foundation, and The Mark Foundation (Co-PI) grants. Her lab research focuses on providing new biomarkers and treatments derived from the novel biology of dormant disease to manage minimal residual disease and prevent metastasis. ~BME Faculty Host: Dr. Luis Solorio ~ -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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Weldon Graduate Program Announcements April 20, 2022
by Siemers, Tammy R 21 Apr '22

21 Apr '22

[4,354 Breaking News Photos and Premium High Res Pictures - Getty Images] Weldon Graduate Program Announcements April 20, 2022 * Career and Internship Opportunities * Intensive Writing Experience for Thesis & Dissertation Writers * Graduate Professional Development Newsletter (April 15) * 9th Annual Online Career Conference for PhDs * Workshops and Deadlines * News from You Career and Internship Opportunities Internship Positions * 2022 Summer Co-op: Downstream Process Improvement, Catalent<https://careers.catalent.com/us/en/job/CATAUS0066659EXTERNALENUS/2022-Summe…> Postdoctoral Positions * NPA Website: https://careers.nationalpostdoc.org/jobs/ Full time Positions * Validation Engineer, Vastek<https://www.simplyhired.com/job/VRL0iRjWCoHf1mV2Y-ELW0aVIPSLhaaEGRg0b4JJQ4i…> * Biomedical Engineer, Analog Devices<https://careers.analog.com/job/ANLGUS11570/Bio-Medical-Engineer?utm_source=…> * Senior/Research Associate, Protein Engineering, 10x Genomics<https://www.simplyhired.com/job/RELf_bE7GpkstdwEbS-MMJeBpSyGMb5YWRZ9cL2elo1…> * Research Associate I, Purification Process Development, Alector<https://jobs.lever.co/alector/3886af0b-63d6-4a42-b17e-04e9c145ae74?lever-or…> * Senior Biomedical Engineer, Zoll LifeVest<https://www.zoll.com/contact/careers-at-zoll/careers-search?rid=1789&source…> * Bioengineer, Forcyte Biotechnologies<https://www.simplyhired.com/job/lMZhNlTXLYif5lzqc_UyMFXRpgBVMo6PYCCZwJjzmcI…> * Strain Engineering Scientist, Lygos, Inc.<https://www.simplyhired.com/job/dArW0fVNMYWr8lgcfYrip6sR2pUSFvW74DeqyqrVosg…> * Purdue Start-up Job Board<https://purduefoundry.com/jobs?utm_source=Foundry+Mailing+List&utm_campaign…>-Foundry Start Up Companies Looking to Hire * ACTS Career Center<https://careers.actscience.org/>-Association for Clinical and Translational Science * Doc Jobs<https://www.docjobs.com/jobs/list/>-Jobs beyond traditional clinical and academic roles Intensive Writing Experience for Thesis & Dissertation Writers The Writing Lab, in collaboration with the Graduate School, is once again offering summer sessions of the Intensive Writing Experience. The purpose of the Intensive Writing Experience is to give masters and doctoral students in good standing with their programs time to write or to revise a thesis or dissertation with support from Writing Lab staff. Participants will receive writing instruction and support from Writing Lab staff, will spend significant time writing or revising their thesis or dissertation, and will network with other graduate writers on campus. Writers can choose a virtual week or an in-person week * May 24-26 (virtual) * May 31-June 2 (virtual) * June 28-30 (in-person) * July 5-7 (in-person) Anyone interested in attending should apply between April 18th and 29th. Complete the application survey here.<https://purdue.ca1.qualtrics.com/jfe/form/SV_af4B9gi3aLLxP9A>. For more information, see the information sheet on the webpage <https://owl.purdue.edu/writinglab/students/graduate_writing_events.html> or email Writing.Lab(a)purdue.edu<mailto:Writing.Lab@purdue.edu> and include IWE in the subject line. Graduate Professional Development Newsletter (April 15) https://mailimages.purdue.edu/vo/?FileID=635c1566-68fd-42b1-81a7-f2da613b49… 9th Annual Online Career Conference for PhDs Just a reminder, our 9th Annual Online Career Conference for Graduate Students and PhDs is coming up on May 7th and May 14th 2022. Over the past 8 years, this conference has helped nearly 10,000 doctoral students, PhDs, and postdocs to job search and build careers beyond the professoriate. The conference teaches graduate students and postdocs proven job search strategies to launch non-faculty careers. https://beyondprof.com/conference/<https://beyondprof.lt.acemlna.com/Prod/link-tracker?redirectUrl=aHR0cCUzQSU…> Information about the conference is included below: Beyond the Professoriate's 9th Annual Online Career Conference for PhDs Presented by the Global Higher Education Division of ETS Leaving academia can feel like a big, mysterious step into the unknown. After years of being successful in academia, it can be daunting and overwhelming to launch a professional job search. For the past 8 years, this conference has helped nearly 10,000 doctoral students and PhDs confidently explore career options and begin their job search. The conference features 16 PhDs who have been where you are now, but have successfully made the leap into industry where they are thriving. They want to help you do the same. By attending this conference, you'll build foundational knowledge you need to be successful in your job search. You'll also have the chance to hear directly from PhDs about their experience job searching, interviewing, and building new professional communities. Attend Live: May 7th & 14th, starting at 11:00 AM (ET) both days. Conference is virtual via Zoom webinar. Video Replay: Yes! 30 day replay is available to all ticket holders. Price: $67 to attend live and unlock the replay For more information and to register: https://beyondprof.com/conference/<https://beyondprof.lt.acemlna.com/Prod/link-tracker?redirectUrl=aHR0cHMlM0E…> Program Overview: 7 May 2022 11 a.m. ET to 4 p.m. ET One hour instructional webinars to teach you jobs search strategies. Topics include: * How to Use Assessments to Explore Career Options * Identifying Your Most Marketable Skills * How to Research Career Options that are Right for You * How to Communicate Your Value to Employers 14 May 2022 11 a.m. ET to 4 p.m. ET Panel discussions with PhDs who have launched successful non-faculty careers. Topics include: * Building a Professional Community * Hiring and Negotiating in a Nonacademic Job * Deciding to Leave Academia * Transitioning into a 9 to 5 Job Advanced registration is required. https://beyondprof.com/conference/<https://beyondprof.lt.acemlna.com/Prod/link-tracker?redirectUrl=aHR0cHMlM0E…> Workshops and Deadlines Here are some upcoming workshops and deadlines more detailed information about the workshops will be sent out separately closer to the event. April 29th Deadline to apply for summer Intensive Writing Experience (IWE) April 30th Bloomberg Data Science Fellowship Due<https://www.techatbloomberg.com/bloomberg-data-science-ph-d-fellowship/> May 4th OIGP Spring Reception May 5th Faculty Coffee Chat: Professor Alexandria Volkening May 13th Peer Mentoring Grab and Go Lunch News from You Please inform Tammy of honors, awards, or other accolades (to include having a paper published) you receive so that the Weldon School may recognize your accomplishments. Send the complete information - specific title and nature of the award, name of conference or event at which award was given, date of said event, photograph if available, etc. - to tsiemers(a)purdue.edu<mailto:tsiemers@purdue.edu>. Tammy Siemers Senior Graduate Training Program Administration and Professional Development Specialist Weldon School of Biomedical Engineering 206 S. Martin Jischke Drive, West Lafayette, IN 47907-2032 o: 765-496-0294 Achiever, Relator, Includer, Restorative, Developer [233FFCD4]<https://www.purdue.edu/?utm_source=signature&utm_medium=email&utm_campaign=…>

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BME PhD Preliminary Exam Announcement for Jordanna Payne (L. Solorio advisor)
by May, Sandra M 19 Apr '22

19 Apr '22

BME PhD Preliminary Exam Announcement for Jordanna Payne (L. Solorio advisor) Title: Development and characterization of a subcutaneous porcine ex-vivo tissue culture model Please note this prelim is open only to those who have signed the Lilly NDA. Date: April 26, 2022 Time: 3:00pm EST Location: BRK 1001 Advisory Committee: Luis Solorio, Chair Douglas Brubaker Sherry L. Harbin Michael Wendt Abstract: The subcutaneous route of drug delivery is desirable due to patient comfort and ease of administration. One of the biggest challenges in studying drug delivery in the subcutaneous space is the lack of in-depth knowledge about the composition of the space. Because of this, several drugs encounter difficulty being delivered via this route presenting challenges during clinical trials. Currently, drugs are tested in vitro and in vivo. In vitro experiments are more cost effective but lack the ability to provide information about drug uptake by tissue and other interactions or toxicities. In vivo experiments can provide this information but are costly. There is a need for a platform that can be used to study subcutaneous injection of drugs ex-vivo. This work details the development and validation of a model of ex-vivo subcutaneous porcine tissue culture for up to one week utilizing three distinct anatomical locations from Yucatan mini pigs. Tissue specimens of 12mm in diameter from behind the ear, the breast, and the belly were cultured for seven days with average viability greater than 85%. Next, Liquid Chromatography-Mass Spectrometry (LC-MS) was utilized to track changes in the subcutaneous proteome as a result of time in culture. Next, LC-MS will be utilized to track changes in the subcutaneous proteome of a commercially available ex-vivo human tissue model to compare to the porcine model. Finally, parameters for scaling of the model for high throughput will be determined.

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[Bmeroundtable-list] BME Monday Roundtable - on Tuesday; April 19, 2022
by Gelfand, Johanna K 19 Apr '22

19 Apr '22

[cid:image003.jpg@01D853D0.C59E79B0] BME MONDAY ROUNDTABLE April 18, 2022 PROTECT PURDUE * Masks protocols changed as of March 14! Check for updates https://protect.purdue.edu/required-covid-19-protocols/ * Vaccines are strongly encouraged (though not required) https://protect.purdue.edu/vaccine-information/ * Updated guidance for research SOPs, etc. and Protect Purdue are coming quickly. Please make sure you are staying current with Purdue guidelines. UPCOMING IMPORTANT DATES Week of April 18 Tues., April 19 - Friday, April 27 - Purdue EPICS Design Reviews. Please register to be a reviewer for the Purdue EPICS Design Reviews. Reviewers may attend in-person or online. The students need your professional feedback and input. Link for registration: https://purdue.ca1.qualtrics.com/jfe/form/SV_1N47K6OTs1Zb2hE Please contact Carl Russell III at russ160(a)purdue.edu<mailto:russ160@purdue.edu> with questions. Wed., April 20 - Weldon School of Biomedical Engineering Seminar, 9:30 a.m., MJIS 1001 or via Zoom: https://purdue-edu.zoom.us/j/95150439811?pwd=a3hOK0o0bmpkS3poTVBCbVhDNU9FZz… "The Role of PP2A in the Regulation of Pancreatic Cancer Initiation and Progression," Brittany Allen-Peterson, PhD, Assistant Professor of Biological Sciences, Purdue University. Wed., April 20 - BME Bytes Seminar, 1:30 pm, Location 1083. Presenter: Tyler Diorio. Open to all undergraduate and graduate researchers. Lunch will be provided. Thurs., April 21 - IBSC-BME Preliminary Exam Announcement for Antonia Susnjar (J. Rispoli and T. Talavage, advisors), 10:00 a.m., MJIS 2001 or via Zoom: https://purdue-edu.zoom.us/j/99417184999 Title of presentation: Clinical Applications of Innovative Magnetic Resonance Techniques Thurs., April 21 - Purdue Series on Corporate Citizenship and Ethics, Dr. John Whyte, Chief Medical Officer, WebMD presenting "The FDA and Artificial Intelligence in Health Care," 7:00 p.m., Stewart Center - Loeb Playhouse. Sponsored by Krannert School of Management, College of Education and College of Pharmacy. Fri., April 22 - BME PhD Preliminary Exam Announcement for Rashed Almousa (D. Xie and K. Park, co-advisors), 1:00 p.m., via Zoom: https://purdue-edu.zoom.us/j/92818782481?pwd=YnZVNVl6SmpyYW0xeUVKRU5oRjE4dz… Title of presentation: Hydrogel-coated Polyvinylchloride Surface for Enhanced Antifouling and Biofilm Resistance. Fri., April 22 - BME PhD Defense Announcement for Agudemu Borjigin (H. Bharadwaj, advisor), 1:00 p.m. via Zoom: https://purdue-edu.zoom.us/j/93613037748?pwd=OGpCSjdEV2NqTVJKdjF4T1h1dldhdz… Meeting ID: 936 1303 7748; Passcode: 777827. Title of presentation: The Role of Temporal Fine Structure in Everyday Hearing. Upcoming important deadlines and info. Tues., April 26 - BRAG Session, 12:00 p.m., MJIS 2001, Dr. Young Kim, Associate Head for Research and Associate Professor of Biomedical Engineering, "The good, the bad, and the ugly of clinical research as a biomedical engineering." Wed., April 27 - Engineering Solutions in Pediatric Healthcare, 1:00-4:30 p.m., MJIS 2001 and via Zoom. Join us on April 27 to discuss the intersection of engineering and medicine in pediatric healthcare. Hear from faculty and clinicians from Purdue'sWeldon School of Biomedical Engineering, Indiana University School of Medicine, Riley Children's Hospital and industry experts from Cook Medical. Wed., April 27 - BME PhD Preliminary Exam Announcement for Angel G. Enriquez (H. Lee, advisor), 3:00 p.m., MRGN 129. Title of presentation: Magnetic actuators for smart functionality in biomedical devices. Thurs., April 28-Fri., Apr. 29: Vanderbilt University will be hosting the annual Vanderbilt Integrative Training Alliance (VITA) Symposium, a conference focused on biomedical sciences graduate students. Attendees have a unique opportunity to connect with the Vanderbilt community, obtain a long-term mentoring relationship with a Vanderbilt faculty member, and gain training in scientific communication. The event will also feature a keynote address from Vanderbilt postdoc alumna, Dr. Shaneda Anderson<https://urldefense.com/v3/__https:/nam04.safelinks.protection.outlook.com/?…>. This year the conference will be virtual. Details below. Sun., May 1 - Nominations due from teaching faculty for graduate TA positions. See academic programs update for specifics. Thurs., May 5: Coffee Chat with Faculty: 11:00 am -12:00 pm, Location LYLE (Room TBM). Faculty host: Alexandria Volkening. Potential discussion topics: website development, public science and outreach, social media, academic job materials (with an interdisciplinary perspective) Tues., May 31: Deadline for submission of abstracts for BMES 2022 Annual Meeting, to be held October 12-15 in San Antonio, TX. For more information: https://www.bmes.org/abstract-information This year's meeting theme is "Embracing Inclusion to Advance Innovation in Healthcare and Education" Fri., June 3: Application deadline for Trailblazers in Engineering program. See below for details. SPRING 2022 BME Faculty Meetings All faculty meetings will begin at 11:30 a.m. in MJIS 2001 Fri., April 22 Committee Updates Academic Programs Update Dear BME faculty members, If you have graduate students in your lab who may be interested in serving as a TA this coming year, we need your nominations (including their additional background information) by May 1st, 2022. If your student has a fellowship for the upcoming academic year, we ask that you please refrain from nominating them at this time. In the Weldon School we do our best to distribute teaching assignments to the students who are the best fit for each course. Therefore, if you have any graduate students (residents or international) who you would like to be considered for a TA appointment in the 2022-2023 year, please complete the following survey with the required information for determining best fit: https://purdue.ca1.qualtrics.com/jfe/form/SV_bE3cqxEqECAvDVQ A description of courses is attached for your reference. If you are nominating an international student who has not taken the Oral English Proficiency Test (OEPT), please contact Asem Aboelzahab (aboelzahab(a)purdue.edu<mailto:aboelzahab@purdue.edu>) to schedule your student for the test ASAP (May 7th at the latest). Upcoming test dates will be in June/July. All international students must complete and pass an Oral English Proficiency Test (OEPT) before being certified for a TA assignment. The test does not expire, so a student remains certified for the duration of their position at Purdue. Note that preference will be given to students in the graduate programs of the Weldon School. DEI Committee Update Remaining BME Graduate Peer Mentoring meeting days are: 11-1pm on May 13th Trailblazers in Engineering (TBE) are workshops to prepare future trailblazing faculty in engineering with a focus on preparing outstanding scholars who are also committed to increasing the success of underrepresented communities of engineers. Fellows will network with leading faculty in engineering, thought leaders, program managers at key federal funding agencies, Purdue Engineering heads, and of course, each other. Participants will also meet current Trailblazers and benefit from their inspiring keynote talks. TBE 2022 will be held in person on Purdue's beautiful West Lafayette, IN campus July 26 - 28, 2022. More information and application details for the Black Trailblazers in Engineering (BTE) and Latinx Trailblazers in Engineering (LATinE) program is available at: https://engineering.purdue.edu/Engr/Trailblazers APPLICATION DEADLINE: June 3, 2022 Resources, attachments, further information BME PhD Defense Announcement for Rachel A. Morrison (S. Harbin and J. Rickus, co-advisors), Mon., April 18, 10:00 a.m., MJIS 2001 and via Zoom: https://purdue-edu.zoom.us/j/94970591432?pwd=WmJMbjI1eDYyb08rTmora0N5K29SZz…<https://www.google.com/url?q=https%3A%2F%2Fpurdue-edu.zoom.us%2Fj%2F9497059…> Meeting ID: 949 7059 1432; Passcode: 780258. Title of presentation: Oligomeric collagen encapsulation design and mechanism of protection for beta-cell replacement therapy. Advisory Committee: Sherry L. Harbin, Co-Chair; Jenna L. Rickus, Co-Chair; Kinam Park; Raghavendra G. Mirmira; Robert V. Considine Abstract: Type 1 Diabetes Mellitus (T1D), a chronic disease affecting over 1.5 million Americans, is characterized by the autoimmune destruction of insulin-producing β-cells within pancreatic islets. Islet/β-cell replacement therapies, where replenishable β-cell sources are implanted within protective microenvironments, have the potential to provide a long-term solution for individuals with T1D by restoring glucose-sensitive, insulin release and overall glycemic control. However, most conventional encapsulation materials elicit an immune reaction, known as a foreign body response (FBR), which compromises β-cell health and function. In this dissertation, we designed and evaluated various formulations of a polymerizable collagen, namely type I oligomeric collagen (Oligomer), as encapsulation materials for minimally invasive, subcutaneous delivery of replacement β-cells. Preclinical validation in chemically-induced diabetic mice demonstrated rapid (within 24 hours) reversal of diabetes for beyond 90 days with no signs of rejection or FBR after subcutaneous delivery of both allogeneic and xenogeneic (rat) islets. To further define this uncommon mechanism of protection, the tissue response to Oligomer, in comparison to commercial synthetic and collagen-based materials, was evaluated following subcutaneous implantation within rats, a well-established biocompatibility model. Histological and transcriptomics analyses were used to define the immune response at both cellular and molecular levels. Interestingly, Oligomer showed minimal and transient activation of innate immune cells similar to the sham surgical control, with no evidence of foreign body giant cell formation, inflammatory-mediated bioresorption, or fibrosis. Overall, this work evaluates preclinical efficacy and demonstrates mechanistic understanding of immune tolerance for Oligomer materials for β-cell replacement therapy and other regenerative medicine applications. Weldon School of Biomedical Engineering Seminar, Wed., April 20, 9:30 a.m., MJIS 1001 or via Zoom: https://purdue-edu.zoom.us/j/95150439811?pwd=a3hOK0o0bmpkS3poTVBCbVhDNU9FZz… "The Role of PP2A in the Regulation of Pancreatic Cancer Initiation and Progression," Brittany Allen-Peterson, PhD, Assistant Professor of Biological Sciences, Purdue University. Abstract: Pancreatic cancer is predicted to become the 2nd leading cause of cancer deaths by 2030. KRAS is the most frequently mutated gene in pancreatic ductal adenocarcinoma (PDAC) patients (~90%) and has been shown to contribute to a variety of tumor characteristics. In this presentation we will present data implicating Protein phosphatase 2A (PP2A) as a key regulator of KRAS phenotypes. We demonstrate that suppression of PP2A accelerates PDAC initiation and progression, and that the therapeutic activation of PP2A can prevent nutrient scavenging to drive cancer cell death. Bio: Dr. Brittany Allen-Petersen is an Assistant Professor in the Biological Sciences Department at Purdue University. She obtained her Ph.D. from the University of Colorado and completed an NCI F31 funded postdoctoral fellowship at Oregon Health & Science University. The Allen-Petersen lab broadly focuses on the deregulation of phosphatases in cancer using a variety of models, including 3D culture, in vivo mouse models, and treatment with novel small molecule activators of PP2A. Dr. Allen-Petersen has funding through an NCI K22 Transition Career Development Award and a Pancreatic Cancer Action Network Career Award. ~BME Faculty Host: Dr. Luis Solorio ~ BME Bytes Seminar, Wed., April 20, 1:30 pm, Location MJIS 1083. Presenter: Tyler Diorio (Advised by Dr. Vitaliy Rayz). "Assessing Patient-specific Cardiac-Drive Brain Motion: MRI-based Biomarkers of White Matter Lesion Formation." Open to all undergraduate and graduate researchers. Lunch will be provided. Abstract: In recent years, identifying risks factors associated with cognitive decline (occurring at 46-60 years) and defining mechanisms behind clinically visible damage to the brain (occurring at 60-90 years) has garnered attention from researchers and physicians. Due to the inability of clinical treatment to reverse the deleterious effects of damage to the brain, specifically in the form of white matter lesions, emphasis is heavily placed on disease prevention. We expand upon the vascular dysfunction hypothesis that places cardiovascular risk factors at the precipice of neurodegeneration. Specifically, this work leverages state-of-the-art time-resolved MRI and brain modeling techniques to quantify the contribution of biomechanical, morphological, and clinical risk factors to the manifestation of cognitive decline. Successful identification of biomarkers of neurodegeneration observable in mid-life could provide researchers with a window of opportunity to develop treatments and inform clinical management of risk factors before the damage manifests in irreversible cognitive deficit. About BME Bytes: BME Bytes is designed to help introduce undergraduate Purdue students to the breakthrough research happening at the Weldon School as well as help graduate students develop their professional portfolio by giving invited talks. IBSC-BME Preliminary Exam Announcement for Antonia Susnjar (J. Rispoli and T. Talavage, advisors), 10:00 a.m., Thurs., April 21, MJIS 2001 or via Zoom: https://purdue-edu.zoom.us/j/99417184999 Title of presentation: Clinical Applications of Innovative Magnetic Resonance Techniques Advisory committee: Joseph V. Rispoli, co-chair; Thomas M. Talavage, co-chair; Ulrike Dydak; Uzay Emir Abstract: Magnetic resonance imaging (MRI) has undergone an enormous advancement in diagnostic accuracy through improved comprehensive evaluation of early soft tissue transformation while avoiding the exposure to potentially dangerous ionizing radiation. With decreased cost and enhanced availability, the use of MRI is becoming ever more persuasive throughout clinical practice. Complementary to the MRI, magnetic resonance spectroscopy (MRS) offers unique information about the micromolecular composition of the human body by capturing the chemical signature of metabolites and neurotransmitters via frequency changes and displaying this information in a spectrum. The applications of MRS to investigate the metabolic window on a wide range of biochemical processes are incredibly diverse. For example, we have utilized MRS to investigate the composition and function of the human brain in post-traumatic stress disorder, traumatic brain injury, addiction, and hyperbaric oxygen therapy assessment. In addition to MRS biological specificity, diffusion tensor imaging (DTI) is yet another advanced MRI methodology used to map and characterize the three-dimensional diffusion of water as a function of spatial location. Analogous to the MRS, DTI applications are diverse and not limited to in vivo studies. To address the significant challenges of strict drug user adherence regimens for numerous treatments, we have evaluated the drug release profile from a newly developed in situ forming implants (ISFIs) for sustained and constant drug delivery. Taken together, advanced MRI methods that probe the morphology, microstructure, function, and chemical changes are clinically applicable in various diseases and conditions. BME PhD Preliminary Exam Announcement for Rashed Almousa (D. Xie and K. Park, co-advisors), Fri., April 22, 1:00 p.m., via Zoom: https://purdue-edu.zoom.us/j/92818782481?pwd=YnZVNVl6SmpyYW0xeUVKRU5oRjE4dz… Meeting ID: 928 1878 2481; Passcode: 849982. Title of presentation: Hydrogel-coated Polyvinylchloride Surface for Enhanced Antifouling and Biofilm Resistance. Abstract: Once a medical device is implanted, a series of interactions occur between the surface of the device and the body fluids where proteins start to be adsorbed on the surface which initiates cell and bacterial adhesion, and this can eventually lead to thrombus formation and bacterial contamination. Both of the two complications can significantly reduce the quality and the efficiency of the implanted device and may ultimately reduce the reliability of the implant. The polyvinylchloride (PVC) surface as a common medical material is hydrophobic and highly prone to such complications, urging researchers to develop an enhanced surface coating. Unlike other approaches of inadequate surface coating or limited antifouling polymer density and thickness, we propose to form a hydrogel that is covalently bonded on the PVC surface to significantly reduce protein adsorption, cell adhesion, and biofilm formation by a dense layer of antifouling polymers via surface-initiated polymerization. Hydrogels are prepared based on polymers having the capacity of swelling large amounts of water, which can then effectively repel proteins, cells, and bacteria. The covalently attached hydrogel will be fabricated via a conventional free-radical polymerization initiated through a biocompatible initiator or chain-transfer agent. Conventional free-radical polymerization is efficient, simple, cost-effective, and more friendly to the environment when compared to advanced polymerization methods. We believe that the successful achievement of the project will greatly impact the field of blood, cardiovascular and urological research, and the quality of health care for those requiring PVC-based medical devices and supplies in blood transfusion, cardiovascular and urological applications. BME PhD Defense Announcement for Agudemu Borjigin (H. Bharadwaj, advisor), Fri., April 22, 1:00 p.m. via Zoom: https://purdue-edu.zoom.us/j/93613037748?pwd=OGpCSjdEV2NqTVJKdjF4T1h1dldhdz… Meeting ID: 936 1303 7748; Passcode: 777827. Title of presentation: The Role of Temporal Fine Structure in Everyday Hearing. Advisory committee: Dr. Hari M. Bharadwaj, advisor; Dr. Michael G. Heinz, Dr. Edward L. Bartlett, Dr. Daniel B. Polley Abstract: This thesis aims to investigate how one fundamental component of the inner-ear (cochlear) response to all sounds, the temporal fine structure (TFS), is used by the auditory system in everyday hearing. Although it is well known that neurons in the cochlea encode the TFS through exquisite phase locking, how this initial/peripheral temporal code contributes to everyday hearing and how its degradation contributes to perceptual deficits are foundational questions in auditory neuroscience and clinical audiology that remain unresolved despite extensive prior research. This is largely because the conventional approach to studying the role of TFS involves performing perceptual experiments with acoustic manipulations of stimuli (such as sub-band vocoding), rather than direct physiological or behavioral measurements of TFS coding, and hence is intrinsically limited. The present thesis addresses these gaps in three parts: 1) developing assays that can quantify TFS coding at the individual level 2) comparing individual differences in TFS coding to differences in speech-in-noise perception across a range of real-world listening conditions, and 3) developing deep neural network (DNN) models of speech separation/enhancement to complement the individual-difference approach. By comparing behavioral and electroencephalogram (EEG)-based measures, Part 1 of this work identified a robust test battery that measures TFS processing in individual humans. Using this battery, Part 2 subdivided a large sample of listeners (N=200) into groups with "good" and "poor" TFS sensitivity. A comparison of speech-in-noise scores under a range of listening conditions between the groups revealed that good TFS coding reduces the negative impact of reverberation on speech intelligibility, and leads to reduced reaction times suggesting lessened listening effort. These results raise the possibility that cochlear implant (CI) sound coding strategies could be improved by attempting to provide usable TFS information, and that these individualized TFS assays can also help predict listening outcomes in reverberant, real-world listening environments. Finally, the DNN models (Part 3) introduced significant improvements in speech quality and intelligibility, as evidenced by all acoustic evaluation metrics and test results from CI listeners (N=6). These models can be incorporated as "front-end" noise-reduction algorithms in hearing assistive devices, as well as complement other approaches by serving as a research tool to help generate and rapidly sub-select the most viable hypotheses about the role of TFS coding in complex listening scenarios. BRAG Session, Tues., April 26, 12:00 p.m., MJIS 2001, Dr. Young Kim, Associate Head for Research and Associate Professor of Biomedical Engineering, "The good, the bad, and the ugly of clinical research as a biomedical engineering." Dr Kim writes that he will share multiple failures and a couple of happy stories. Spread the word - bring another postdoc! Raising A Resilient Scientist Workshop Series (Message from Sharon Milgram, Director, NIH Office of Intramural Training & Education): Over the last year I have interacted with many trainees across the U.S. as part of the NIH Becoming a Resilient Scientist series<https://www.training.nih.gov/nih_becoming_a_resilient_scientist_series>. After carefully considering input from students, postdocs, faculty and program administrators who participated in the program, I have decided to offer a series, RAISING A RESILIENT SCIENTIST<https://www.training.nih.gov/workshops_and_trainings_for_extramural_princip…>, for faculty and administrators who mentor students and postdoctoral fellows in the biomedical, behavioral, and social sciences. The goal of the Raising a Resilient Scientist series is to promote the mental health and well-being of the academic research community by supporting faculty and administrators to develop self-management, relationship-management, and mentoring skills. A variety of topics will be covered with a specific focus on communication and shared problem-solving to help trainees deal with the inevitable setbacks experienced in high knowledge environments. There will be five units in the series; each unit will consist of a 75-minute lecture, which can be watched in real-time or asynchronously, followed by a 1-hour facilitated discussion with peers. There will be two opportunities for participation in the small groups following each webinar. There is no charge for participation, but advanced registration is required. For more information, and to register, please visit our webpage<https://www.training.nih.gov/workshops_and_trainings_for_extramural_princip…>. I do not anticipate offering this series again in the future; participation in the entire series is recommended but is not required. Please do not hesitate to email me if you have any questions. Current scheduled workshop dates are April 26 and May 24. Engineering Solutions in Pediatric Healthcare, Wed., April 27, 1:00-4:30 p.m., MJIS 2001 and via Zoom. Join us on April 27 to discuss the intersection of engineering and medicine in pediatric healthcare. Hear from faculty and clinicians from Purdue'sWeldon School of Biomedical Engineering, Indiana University School of Medicine, Riley Children's Hospital and industry experts from Cook Medical. Topics include: * History of biomedical engineering and pediatrics research at Purdue * What research is going on now to treat pediatric disease * Discuss how we can increase collaborative opportunities and overcome challenges in the development and translation of pediatric medical devices Registration is encouraged by April 18. For more information and to register for the event, visit: purdue.link/2022-pediatric-symposium BME PhD Preliminary Exam Announcement for Angel G. Enriquez (H. Lee, advisor), Wed., April 27, 3:00 p.m., MRGN 129. Title of presentation: Magnetic actuators for smart functionality in biomedical devices. Advisory Committee: Hyowon Lee, Chair; Chi Hwan Lee; Luis Solorio; Daniel H. Sahlein Abstract: Magnetism provides numerous advantages to actuating systems, specifically for biomedical applications. The untethered transfer of energy and scalability of magnetic actuators enables functionality to an otherwise passive system. For example, the wireless magnetic actuation can turn static 2D and 3D cell cultures into a more physiologically-relevant dynamic environment while limiting contamination. Moreover, indwelling catheters and implantable sensors are typically stationary devices that are notorious for their short lifespan when implanting into the body due to immune responses. Magnetic microactuators may be used for wireless actuation for in situ removal of biological materials accumulated on chronically implanted devices. In this dissertation, I will demonstrate examples of novel biomedical microdevices enabled by magnetic actuation for added functional benefits. First, I will describe a soft polymer magnetic actuator that can facilitate the study of a physiologically relevant cell culturing system. By cyclically stretching an extracellular matrix protein in a 3D cell culture, this system can elucidate the process by which breast cancer cells respond to a dynamic environment in the lungs. The fibrillar fibronectin suspended across the body of the magnetic actuator provides a matrix representative of early metastasis for 3D cell culture that has not yet been recapitulated in vitro until now. Our findings suggest that this dynamic environment leads to significant matrix degradation in breast cancer cell lines with metastatic potential. Our results demonstrate a clear suppressive cellular response due to cyclic stretching that has implications for a mechanical role in the dormancy and reactivation of disseminated breast cancer cells to macrometastases. As a second application, I will demonstrate the use of magnetic microactuators to remove biofouling on an implantable biosensor in order to prolong its functionality. The results of our work suggest that the motion of the actuator on the sensor surface can maintain biosensor signal integrity and prevents the downstream effects of the foreign body response. In the future, I plan to evaluate the performance of the self-clearing biosensor in vivo to demonstrate chronic and reliable sensor functionality. Vanderbilt Integrative Training Alliance (VITA) Symposium, April 28-29: On April 28-29th, Vanderbilt University will be hosting the annual Vanderbilt Integrative Training Alliance (VITA) Symposium, a conference focused on biomedical sciences graduate students. Attendees have a unique opportunity to connect with the Vanderbilt community, obtain a long-term mentoring relationship with a Vanderbilt faculty member, and gain training in scientific communication. The event will also feature a keynote address from Vanderbilt postdoc alumna, Dr. Shaneda Anderson<https://urldefense.com/v3/__https:/nam04.safelinks.protection.outlook.com/?…>. This year the conference will be virtual. The complete two day schedule can be found here<https://urldefense.com/v3/__https:/nam04.safelinks.protection.outlook.com/?…>. While the symposium is open to all, we particularly encourage individuals from backgrounds underrepresented in academia to apply, including but not limited to those who identify as Black, African-American, Latino, Hispanic, Native American, or Pacific Islander, those who have a disability, first generation college-goers, those from disadvantaged socio-economic backgrounds, and those underrepresented on the basis of gender identity or expression or sexual orientation. I am hoping that we will have representation from every Big 10 school (University of Illinois, Indiana University, University of Iowa, University of Maryland, University of Michigan, Michigan State University, University of Minnesota, University of Nebraska-Lincoln, Northwestern University, Ohio State University, Pennsylvania State University, Purdue University, Rutgers University-New Brunswick, and the University of Wisconsin-Madison). Do you know of any students who would be interested in applying? If so, please respond to antentor.o.hinton.jr(a)Vanderbilt.Edu<mailto:antentor.o.hinton.jr@Vanderbilt.Edu> with their name and email and a member of our team will reach out. Thank you for your consideration, Antentor Othrell Hinton, Jr., Ph.D. Pronouns: He/Him/His Twitter: @phdgprotein86 LinkedIn: https://www.linkedin.com/in/biogeek26/<https://urldefense.com/v3/__https:/www.linkedin.com/in/biogeek26/__;!!DZ3fj…> Lab Twitter: @AtHinton EE Just Faculty Scholar (UNCF award) Assistant Professor Department of Molecular Physiology and Biophysics Vanderbilt School of Medicine Basic Sciences The Vanderbilt Diabetes Research and Training Center Poster Submission Application and Details<https://www.purdue.edu/gradschool/oigp/events/spring-reception/submission.h…> Award Application and Details<https://www.purdue.edu/gradschool/oigp/events/spring-reception/award-applic…> Trailblazers in Engineering (TBE) are workshops to prepare future trailblazing faculty in engineering with a focus on preparing outstanding scholars who are also committed to increasing the success of underrepresented communities of engineers. Trailblazers in Engineering Fellows are selected not only for their outstanding scholarly achievements but also for their potential impact in expanding representation and diversity in engineering. The workshop will provide Fellows the ability to network with leading faculty in engineering, thought leaders, program managers at key federal funding agencies, Purdue Engineering heads, and of course, each other. Participants will also meet current Trailblazers and benefit from their inspiring keynote talks. TBE 2022 will be held in person on Purdue's beautiful West Lafayette, IN campus July 26 - 28, 2022. APPLICATION DEADLINE: June 3, 2022 Reasons to Attend 1. Network with leading trailblazing faculty in engineering, thought leaders, program managers at key federal funding agencies, Purdue Engineering heads, and scientists who will present keynote speeches and talks throughout the program. 2. Gain insight into what academic success will look like post-pandemic. 3. Participate in panel discussions. * Why choose an academic career? * How to apply & interview? * How to negotiate salary and start-up packages? * How to get early career research funding? 4. Meet program managers from the National Science Foundation, Office of Naval Research, Air Force Office of Scientific Research, National Institutes of Health and others; receive advice on your proposals; and participate in a poster session to pitch your research and teaching plans and get feedback from would-be employers. 5. Attend the "Success Strategies for New Faculty Members" workshop presented by internationally recognized experts in faculty development, Drs. Richard Felder and Rebecca Brent. 6. For non-Purdue Fellows, we are reimbursing up to $800.00 per Economy flight and transportation (cab fare, shuttle, mileage, and/or parking to/from Purdue). In addition, we will provide two days of per diem for travel days of July 25 & 28. APPLICATION DEADLINE: June 3, 2022 Applicants are invited to apply through two programs, Black Trailblazers in Engineering (BTE)<https://maillinks.purdue.edu/t/42895178/1487133596/88073767/0/120588/?f5d63…> and Latinx Trailblazers in Engineering (LATinE)<https://maillinks.purdue.edu/t/42895178/1487133596/88073768/0/120588/?f5d63…>. Please visit these pages for details. Attachments BME Course Descriptions -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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[Bmeroundtable-list] BME Seminar - Wednesday, April 20
by Gelfand, Johanna K 18 Apr '22

18 Apr '22

[cid:image001.jpg@01D85338.D8C7DB00] Weldon School of Biomedical Engineering Seminar Series Wednesday, April 20, 2022 9:30-10:20am MJIS 1001 or Via Zoom: https://purdue-edu.zoom.us/j/95150439811?pwd=a3hOK0o0bmpkS3poTVBCbVhDNU9FZz… The Role of PP2A in the Regulation of Pancreatic Cancer Initiation and Progression [cid:image002.jpg@01D85338.D8C7DB00] Brittany Allen-Petersen, PhD. Assistant Professor of Biological Sciences Purdue University Abstract: Pancreatic cancer is predicted to become the 2nd leading cause of cancer deaths by 2030. KRAS is the most frequently mutated gene in pancreatic ductal adenocarcinoma (PDAC) patients (~90%) and has been shown to contribute to a variety of tumor characteristics. In this presentation we will present data implicating Protein phosphatase 2A (PP2A) as a key regulator of KRAS phenotypes. We demonstrate that suppression of PP2A accelerates PDAC initiation and progression, and that the therapeutic activation of PP2A can prevent nutrient scavenging to drive cancer cell death. Bio: Dr. Brittany Allen-Petersen is an Assistant Professor in the Biological Sciences Department at Purdue University. She obtained her Ph.D. from the University of Colorado and completed an NCI F31 funded postdoctoral fellowship at Oregon Health & Science University. The Allen-Petersen lab broadly focuses on the deregulation of phosphatases in cancer using a variety of models, including 3D culture, in vivo mouse models, and treatment with novel small molecule activators of PP2A. Dr. Allen-Petersen has funding through an NCI K22 Transition Career Development Award and a Pancreatic Cancer Action Network Career Award. ~BME Faculty Host: Dr. Luis Solorio ~ -- Bmeroundtable-list mailing list Bmeroundtable-list(a)ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list

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Weldon Graduate Program Announcements April 13, 2022
by Siemers, Tammy R 13 Apr '22

13 Apr '22

[4,354 Breaking News Photos and Premium High Res Pictures - Getty Images] Weldon Graduate Program Announcements April 13, 2022 * Career and Internship Opportunities * Graduate Professional Development Newsletter (April 8) * Summer Science Program in Genomics: please help us find one more TA * Chief Medical Officer from WebMD - Guest Lecture Series Invitation * Workshops and Deadlines * News from You Career and Internship Opportunities Internship Positions * 2022 Summer Co-op: Downstream Process Improvement, Catalent<https://careers.catalent.com/us/en/job/CATAUS0066659EXTERNALENUS/2022-Summe…> * Summer/Fall Co-op 2022, Quality Engineer, Alcon<https://alcon.wd5.myworkdayjobs.com/en-US/careers_alcon/job/Johns-Creek-Geo…> Postdoctoral Positions * NPA Website: https://careers.nationalpostdoc.org/jobs/ Full time Positions * Clinical Research Associate, Health Tech, Meta<https://www.linkedin.com/jobs/view/3015577809/?eBP=NotAvailableFromMidTier&…> * Sr. R&D Engineer, Shockwave Medical<https://jobs.jobvite.com/careers/shockwavemedical/job/oSOijfw1?__jvst=job%2…> * Device Engineer II, AVB Consulting<https://www.simplyhired.com/job/W5-EXlNdSIN3RbvUhHTnaM8ESUgx0biVtzX__qiulKJ…> * Senior Product Development Engineer, Noble International<https://www.simplyhired.com/job/RAxs7wDq6xBCnhETD9PIrXlyq9bokDK4VxwN8uBbwvh…> * Scientist I, Protein Engineering, 23andMe<https://www.simplyhired.com/job/v78VgJrWw19pDg7OTJdGL1LJilbLS8nHAP2wAaZbSVR…> * Chemical Engineer/Biomedical Engineer, Oakwood Labs<https://www.simplyhired.com/job/wCl4SO717QH7Psgd5OQsgt7h6STJWcUGRmUFCEd7YVY…> * Research Engineer, Cook Medical<https://americas-cookmedical.icims.com/jobs/10611/job?utm_source=indeed_int…> * Purdue Start-up Job Board<https://purduefoundry.com/jobs?utm_source=Foundry+Mailing+List&utm_campaign…>-Foundry Start Up Companies Looking to Hire * ACTS Career Center<https://careers.actscience.org/>-Association for Clinical and Translational Science * Doc Jobs<https://www.docjobs.com/jobs/list/>-Jobs beyond traditional clinical and academic roles Graduate Professional Development Newsletter (April 8) https://mailimages.purdue.edu/vo/?FileID=7d96a447-8593-415b-ba28-e777d83707… Summer Science Program in Genomics: please help us find one more TA An opportunity for undergrads or graduate students to be involved with a highly regarded STEM program for High School students. Students should not have other commitments during the Summer Science Program as it is definitely a full-time commitment. The Summer Science Program in Genomics at Purdue University Teaching Assistant and Residential Mentors are tutors and instructors, assisting participants in using equipment and software, and with problem sets, under the direction of the Academic Director. Equally important is their simultaneous role as residential advisors and personal mentors, supervising participants and organizing recreational and social activities, under the direction of the Site Director. Room & board and travel are provided, plus a salary of about $1,000 per week for 6 1/2 weeks. Working in teams of three, participants will use a programmable chemostat to expose a marine microbe to an antibiotic, then analyze the mutations observed in the evolved genome. Applicants should be rising college seniors, graduating seniors, or graduate students with wet lab or genomics/bioinformatics knowledge and experience, who enjoy teaching. About the research<https://summerscience.org/the-ssp-experience/directed-evolution/> Learn more and apply online<https://summerscience.org/employment/> Chief Medical Officer from WebMD - Guest Lecture Series Invitation See Attached On Thursday, April 21st at 7:00 p.m. in Loeb Playhouse, the Krannert School is hosting a speaker as part of the Purdue Series on Corporate Citizenship and Ethics in partnership with the College of Education and the College of Pharmacy. We are excited to welcome to campus John Whyte, Chief Medical Officer at WebMD<https://krannert.purdue.edu/events/ethics/speakers/john-whyte.php> who will be giving a talk on the ethical considerations and the potential benefits and pitfalls of medical A.I. Attached is a flyer with more details. Workshops and Deadlines Here are some upcoming workshops and deadlines more detailed information about the workshops will be sent out separately closer to the event. April 14th Debt Management (Grad School<https://gspd.gosignmeup.com/public/Course/browse?viewstate=eyJWaWV3TGlzdFR5…>) April 14th Inaugural IBSc Symposium April 30th Bloomberg Data Science Fellowship Due<https://www.techatbloomberg.com/bloomberg-data-science-ph-d-fellowship/> May 4th OIGP Spring Reception May 5th Faculty Coffee Chat: Professor Alexandria Volkening May 13th Peer Mentoring Grab and Go Lunch News from You Please inform Tammy of honors, awards, or other accolades (to include having a paper published) you receive so that the Weldon School may recognize your accomplishments. Send the complete information - specific title and nature of the award, name of conference or event at which award was given, date of said event, photograph if available, etc. - to tsiemers(a)purdue.edu<mailto:tsiemers@purdue.edu>. Tammy Siemers Senior Graduate Training Program Administration and Professional Development Specialist Weldon School of Biomedical Engineering 206 S. Martin Jischke Drive, West Lafayette, IN 47907-2032 o: 765-496-0294 Achiever, Relator, Includer, Restorative, Developer [233FFCD4]<https://www.purdue.edu/?utm_source=signature&utm_medium=email&utm_campaign=…>

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