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This week's seminar announcement
by Shafer, Marsha L 02 Nov '15

02 Nov '15

REMINDER: This week's seminar announcement - [cid:image001.png@01D11553.E7C91940]<https://engineering.purdue.edu/ChE> Purdue University School of Chemical Engineering GRADUATE SEMINAR SERIES Dr. Francis J. Doyle, III John A. Paulson Dean Harvard's Paulson School of Engineering & Applied Sciences Harvard University "Engineering the Artificial Pancreas" Tuesday, November 3, 2015 3:00 - 4:15 p.m. FRNY G140 Reception at 2:30 p.m. in Henson Atrium Abstract: Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease affecting approximately 35 million individuals world-wide, with associated annual healthcare costs in the US estimated to be approximately $15 billion. Current treatment requires either multiple daily insulin injections or continuous subcutaneous (SC) insulin infusion (CSII) delivered via an insulin infusion pump. Both treatment modes necessitate frequent blood glucose measurements to determine the daily insulin requirements for maintaining near-normal blood glucose levels. Twenty years ago, in the School of Chemical Engineering at Purdue, I began a research quest to design an artificial pancreas for patients with type 1 diabetes mellitus (T1DM). The closed-loop concept consisted of an insulin syringe, a blood glucose analyzer, and a transmitter. In the ensuing years, a number of theoretical research studies were performed with numerical simulations to demonstrate the relevance of advanced process control design to the artificial pancreas, with delivery algorithms ranging from simple PID, to H-infinity, to model predictive control. With the advent of continuous glucose sensing, which reports interstitial glucose concentrations approximately every minute, and the development of hardware and algorithms to communicate with and control insulin pumps, the vision of closed-loop control of blood glucose is approaching a reality. In the last 10 years, our research group has been working with medical doctors on clinical demonstrations of feedback control algorithms for the artificial pancreas. In this talk, I will outline the difficulties inherent in controlling physiological variables, the challenges with regulatory approval of such devices, and will describe a number of process systems engineering algorithms we have tested in clinical experiments for the artificial pancreas. Our algorithmic developments have focused on variations of model predictive control, including customized patient models and asymmetric cost functions to deal with hyper- and hypo-glycemic excursions. The latest results from longer term clinical trials, including studies with adolescents, will be reported. Bio: Frank Doyle is the John A. Paulson Dean of the School of Engineering and Applied Sciences at Harvard University, where he also is the John A. & Elizabeth S. Armstrong Professor. Prior to that he was the Mellichamp Professor at UC Santa Barbara, where he was the Chair of the Department of Chemical Engineering, the Director of the UCSB/MIT/Caltech Institute for Collaborative Biotechnologies, and the Associate Dean for Research in the College of Engineering. He received a B.S.E. degree from Princeton, C.P.G.S. from Cambridge, and Ph.D. from Caltech, all in Chemical Engineering. He has also held faculty appointments at Purdue University and the University of Delaware, and held visiting positions at DuPont, Weyerhaeuser, and Stuttgart University. He has been recognized as a Fellow of multiple professional organizations including: IEEE, IFAC, AIMBE, and the AAAS. He is the President for the IEEE Control Systems Society, and is the Vice President of the International Federation of Automatic Control. In 2005, he was awarded the Computing in Chemical Engineering Award from the AIChE for his innovative work in systems biology, and in 2015 received the Control Engineering Practice Award from the American Automatic Control Council for his development of the artificial pancreas. His research interests are in systems biology, network science, modeling and analysis of circadian rhythms, and drug delivery for diabetes. School of Chemical Engineering<https://engineering.purdue.edu/ChE> Purdue University West Lafayette, IN 47907 (765) 494-4050<tel:+17654944050> (c) 2015 Purdue University<http://www.purdue.edu/purdue/disclaimer.html> All rights reserved An equal access/equal opportunity university<http://www.purdue.edu/purdue/ea_eou_statement.html> Marsha Marsha Shafer Chemical Engineering Purdue University Forney Hall, Room G027 480 Stadium Mall Drive West Lafayette, IN 47907-2100 (765) 494-4069 mlshafer(a)purdue.edu

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REMINDER: CoE United Way Bake Sale TODAY Friday October 30 11am-2pm ARMS atrium
by Hadley, JoAnna M 30 Oct '15

30 Oct '15

Good morning! Just a reminder that College of Engineering United Way Bake Sale today Friday, October 30th from 11am to 2pm in the ARMS atrium. We are getting really close to the end of 2015 United Way campaign. As of the end of October Purdue University is 78.73% towards meeting our goal of raising $760,000 with College of Engineering raising $34,615.20. Please remember to return your envelopes with your name on the outside, even if you do not choose to donate, to me in the Business Office FRNY 1057. For more information about United Way please feel free to watch this short video<https://www.youtube.com/watch?v=PNbuyvugQSY> or by visiting www.purdue.edu/unitedway<http://www.purdue.edu/unitedway>. [cid:image001.jpg@01D112EA.70A27FC0] JoAnna Hadley Account Clerk Forney Hall of Chemical Engineering, Room 1057 480 Stadium Mall Drive West Lafayette, IN 47907-2100 765-494-4072 Fax: 765-494-4073 hadleyj(a)purdue.edu<mailto:hadleyj@purdue.edu>

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Shinbeom Lee Dissertation Defense, Tuesday, November 3rd, 2015
by Johnson, Beverly J 28 Oct '15

28 Oct '15

Good afternoon, This e-mail is to announce that Shinbeom Lee will be defending his dissertation, Multiphase Reaction Studies in Stirred Tank and Fixed Bed Reactors, on Tuesday, November 3rd, 2015 at 9:30 AM in FRNY 3062B. The dissertation is being directed by Dr. Varma, and the abstract is attached. All are welcome to attend. Thank you! Bev Johnson Graduate Program Administrator Chemical Engineering Forney Hall 1051 Purdue University 765-494-4057

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Construction update - FYI
by Farmus, Cristina D 27 Oct '15

27 Oct '15

On Friday, October 30, concrete will be poured on the roof of Forney Hall in preparation for the air handling system. A concrete pump will be placed on the driveway between FRNY and PHYS and concrete trucks will enter and exit that zone from 9.00 am to 12.00 pm. This activity will not affect building operations and all entrances will remain open. Cristina Cristina Farmus Managing Director Chemical Engineering Purdue University 765 494 0027 cfarmus(a)purdue.edu<mailto:cfarmus@purdue.edu>

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Graduate Seminar Series - Dr. Francis Doyle, III - Nov. 3, 2015
by Shafer, Marsha L 26 Oct '15

26 Oct '15

Seminar next week: [cid:image003.png@01D10FF4.D74E8820]<https://engineering.purdue.edu/ChE> Purdue University School of Chemical Engineering GRADUATE SEMINAR SERIES Dr. Francis J. Doyle, III Dean, School of Engineering & Applied Sciences Harvard University "Engineering the Artificial Pancreas" Tuesday, November 3, 2015 3:00 - 4:15 p.m. FRNY G140 Reception at 2:30 p.m. in Henson Atrium Abstract: Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease affecting approximately 35 million individuals world-wide, with associated annual healthcare costs in the US estimated to be approximately $15 billion. Current treatment requires either multiple daily insulin injections or continuous subcutaneous (SC) insulin infusion (CSII) delivered via an insulin infusion pump. Both treatment modes necessitate frequent blood glucose measurements to determine the daily insulin requirements for maintaining near-normal blood glucose levels. Twenty years ago, in the School of Chemical Engineering at Purdue, I began a research quest to design an artificial pancreas for patients with type 1 diabetes mellitus (T1DM). The closed-loop concept consisted of an insulin syringe, a blood glucose analyzer, and a transmitter. In the ensuing years, a number of theoretical research studies were performed with numerical simulations to demonstrate the relevance of advanced process control design to the artificial pancreas, with delivery algorithms ranging from simple PID, to H-infinity, to model predictive control. With the advent of continuous glucose sensing, which reports interstitial glucose concentrations approximately every minute, and the development of hardware and algorithms to communicate with and control insulin pumps, the vision of closed-loop control of blood glucose is approaching a reality. In the last 10 years, our research group has been working with medical doctors on clinical demonstrations of feedback control algorithms for the artificial pancreas. In this talk, I will outline the difficulties inherent in controlling physiological variables, the challenges with regulatory approval of such devices, and will describe a number of process systems engineering algorithms we have tested in clinical experiments for the artificial pancreas. Our algorithmic developments have focused on variations of model predictive control, including customized patient models and asymmetric cost functions to deal with hyper- and hypo-glycemic excursions. The latest results from longer term clinical trials, including studies with adolescents, will be reported. Bio: Frank Doyle is the John A. Paulson Dean of the School of Engineering and Applied Sciences at Harvard University, where he also is the John A. & Elizabeth S. Armstrong Professor. Prior to that he was the Mellichamp Professor at UC Santa Barbara, where he was the Chair of the Department of Chemical Engineering, the Director of the UCSB/MIT/Caltech Institute for Collaborative Biotechnologies, and the Associate Dean for Research in the College of Engineering. He received a B.S.E. degree from Princeton, C.P.G.S. from Cambridge, and Ph.D. from Caltech, all in Chemical Engineering. He has also held faculty appointments at Purdue University and the University of Delaware, and held visiting positions at DuPont, Weyerhaeuser, and Stuttgart University. He has been recognized as a Fellow of multiple professional organizations including: IEEE, IFAC, AIMBE, and the AAAS. He is the President for the IEEE Control Systems Society, and is the Vice President of the International Federation of Automatic Control. In 2005, he was awarded the Computing in Chemical Engineering Award from the AIChE for his innovative work in systems biology, and in 2015 received the Control Engineering Practice Award from the American Automatic Control Council for his development of the artificial pancreas. His research interests are in systems biology, network science, modeling and analysis of circadian rhythms, and drug delivery for diabetes. School of Chemical Engineering<https://engineering.purdue.edu/ChE> Purdue University West Lafayette, IN 47907 (765) 494-4050<tel:+17654944050> (c) 2015 Purdue University<http://www.purdue.edu/purdue/disclaimer.html> All rights reserved An equal access/equal opportunity university<http://www.purdue.edu/purdue/ea_eou_statement.html> Marsha Marsha Shafer Chemical Engineering Purdue University Forney Hall, Room G027 480 Stadium Mall Drive West Lafayette, IN 47907-2100 (765) 494-4069 mlshafer(a)purdue.edu

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WebEx Training
by Jackson, Christa N 26 Oct '15

26 Oct '15

Hello, With WebEx becoming more popular, I have set up for ITap to have a training in Forney on December 11 at 2:00 pm in 3059. I will send out a reminder closer to the date along with the WebEx link to be able to join the training if you are unable to attend. In the meantime if you have not already done this, go to https://purdue.webex.com/mw3000/mywebex/default.do?siteurl=purdue using your career account to get started. I look forward to seeing you soon. Thank you, Christa Jackson Forney Hall School of Chemical Engineering, 480 Stadium Mall Drive Room1060 West Lafayette, IN 47907 Phone(765)494-4050 jacksonc(a)purdue.edu

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Caitlin Schram Dissertation Defense, Thursday, October 29th, at 3:00 p.m. in FRNY G060A
by Green, Corwin S 23 Oct '15

23 Oct '15

This e-mail is to announce that Caitlin Schram will be defending her dissertation, Impact of Polymers on the Solution Crystal Growth Rate of a Poorly Water-Soluble Active Pharmaceutical Ingredient, on Thursday, October 29, at 3:00 p.m. in FRNY G060A. The dissertation is directed by Dr. Beaudoin, and the abstract is below. All are welcome to attend. Abstract: Poor aqueous solubility is a major impediment to the oral delivery of over 75% of pharmaceutical compounds currently under development. The bioavailability of these compounds can be enhanced with the use of supersaturating dosage forms, due to their high flux rates across the gastrointestinal tract membrane. However, the success of this strategy hinges on the ability to inhibit crystallization of the supersaturated drug solutions. Polymers can be used to inhibit crystallization and prolong supersaturation, however the mechanisms of polymer inhibition are not yet fully understood. Therefore it is desirable to understand the attributes that render a polymer effective. In this work, the crystal growth rate of a poorly soluble pharmaceutical compound, felodipine, was measured in the presence of various polymers. The growth rate studies were performed using a rotating disk apparatus so that the growth kinetics could be controlled and mathematically modeled. It was found that both polymer ionization state and polymer hydrophobicity greatly impacted polymer effectiveness. Investigation of these systems with atomic force microscopy (AFM) revealed that these properties significantly impacted adsorbed polymer conformation. The polymers that adsorbed in an extended chain conformation were able to achieve a higher degree of surface coverage than those that adsorbed in a coiled globule formation. The surface coverage was found to directly correlate to polymer effectiveness. By modeling this correlation using the Kubota-Mullin model, polymer effectiveness could be predicted when surface coverage was known. This research also assessed the ability of a polymer to impact crystal morphology. It was found that when polymers were present during crystal evolution from an amorphous melt, they were able to impact the size and shape of the resulting crystals. This in turn influenced the rate of crystal growth from supersaturated solutions. Corwin Green Graduate Office Secretary School of Chemical Engineering Purdue University 480 Stadium Mall Drive West Lafayette, IN 47907 E-mail: csgreen(a)purdue.edu<mailto:csgreen@purdue.edu> www.engineering.purdue.edu/ChE<https://engineering.purdue.edu/ChE/index.html>

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CHANGE IN DATE: CoE United Way Bake Sale now Friday October 30
by Hadley, JoAnna M 23 Oct '15

23 Oct '15

I apologize as I was just informed this morning the College of Engineering United Way Bake Sale has been moved to a new date - Friday, October 30th, 11-2 in the ARMS atrium. Rebecca Whitley in Aeronautics and Astronautics created a new poster you can use to publicize the sale in your area. Thanks, JoAnna JoAnna Hadley Account Clerk Forney Hall of Chemical Engineering, Room 1057 480 Stadium Mall Drive West Lafayette, IN 47907-2100 765-494-4072 Fax: 765-494-4073 hadleyj(a)purdue.edu<mailto:hadleyj@purdue.edu> From: Hadley, JoAnna M Sent: Wednesday, October 21, 2015 8:50 AM To: chme(a)ecn.purdue.edu Subject: REMINDER United Way Bake Sale October 29! Purdue Today asked why do Purdue faculty & staff contribute to the United Way? Good morning everyone, Reminder that College of Engineering will be having a United Way Bake Sale on Thursday October 29, 2015 in ARMS atrium from 11am to 2pm. I have made a poster attached, please feel free to spread the word by hanging up the poster in your area. Please remember to return your envelopes with your name on the outside, even if you do not choose to donate, to me in the Business Office FRNY 1057. The Purdue United Way Campaign<http://www.purdue.edu/unitedway/> began in September, offering another occasion for faculty and staff to demonstrate their commitment to bettering the community. Purdue Today asked its readers why they contribute to the United Way. Here are their responses: Annette Brown, diversity outreach project manager, Office of the Provost The United Way is special to me for a few reasons. First, in the 1980s I worked for the United Way as information and referral coordinator. Second, when I needed day care for my daughter, she went to a United Way-funded agency where she was provided with exceptional care. Third, my mother was diagnosed with Alzheimer's disease, and at one point we had to put her in adult day care, which was a United Way-funded agency. She, too, received amazing care and support. Lastly, when I came to work at Purdue, I brought with me my 9-year old-daughter. When I asked about child care for her in the summer, someone suggested the Hanna Community Center. There she was cared for and nurtured by amazing staff and volunteers. My involvement with the United Way, both as a service provider and recipient, has been a wonderful long-term relationship. Tom Brown, facilities assistant/copy operator, Krannert School of Management I give to the United Way because one of my daughters gains services from one of the agencies. And, one day, any of us may be accessing one or more of the agencies as we age and retire. Raymond Daniels, plant electrician, Heat and Power When my children were young, we used their program for vaccinations, so I thought it would be nice to pay back. Larry French, manager of learning spaces operations, IT Customer Relations I am proud to work at a university that does so much to support our local United Way campaign. The funds contributed by Purdue staff each year help build and sustain the type of community we all want to live in and demonstrate Purdue's commitment to the "town and gown" philosophy. When 18 percent of the children in our county live in poverty, we know there is a lot more work to do. And this work cannot be completed by United Way agencies without the essential contribution by Purdue staff each year. My family has directly benefited from the work of UW-funded efforts like Dream Up, which helps middle school students discover career opportunities. In addition, I have observed the great work done by Read to Succeed, YMCA, Bauer Family Resource Center and more. I am happy to do whatever I can to support this important work. Cheryl Gray, benefits systems and information manager, Human Resources A person never knows when some action or event might turn their life upside down and suddenly be in a situation where assistance is needed. United Way has connections with many organizations that help individuals and families depending on their need. I'm fortunate enough to have the means to contribute, and helping others help others is the right thing to do. Brian Hudson, senior advisor of Lean Six Sigma, Purdue Healthcare Advisors As a young person working at an area business I began giving to United Way because I thought it was the right thing to do and also because I wanted to be entered into the prize drawings they had, but that all changed a few years ago. Before joining Purdue, I was asked to be a loaned campaign representative by a local employer. In the role of LCR we went to local companies to talk with employees about the campaign and how their donations are used to fund local organizations and their programs. In preparing to do the presentations, we had several days of training about United Way and the partner organizations they support so we could speak about them during our presentations. With that we had an introduction to all of the organizations, and many of those presentations were on location at Food Finders, Bauer Family Resource Center, Lafayette Transitional Housing and Lafayette Adult Resource Academy. Seeing those facilities and the people they served really impacted me. As I reflected on what I saw, I realized that there were several common themes: * The amazing care and compassion they have for people that come to them. * How resourceful they are with the funding they receive, to make every dollar stretch as far as it can. * How well all the community partners connect so they don't overlap services and they get people to the help they need. Being there and seeing these organizations really made me appreciate what they do and how they do it. Although I'm not able to be there helping them each day, my donation from every paycheck allows them to serve, and that's how I can help. Dr. David Huse, clinical assistant professor of comparative and applied anatomy, Department of Basic Medical Sciences I give to United Way for three reasons. First, United Way is the major source of funding for a huge number of local organizations serving thousands of your neighbors in Lafayette, West Lafayette and Tippecanoe County. Every donation regardless of size benefits people you see every day. These organizations help a very wide range of people, from infants to the elderly. Second, I appreciate that I can designate my contribution to go to specific organizations that mean something special to me. This makes my gift feel even more personal. Third, with payroll deduction through Purdue, it is a simple process and allows me to give more since the payments are spread out over the course of a year. Once I turn my United Way card into my representative, I forget about it until tax time when I have a ready-made charitable deduction. I urge everyone to donate something and help make a difference in the local community. Rhonda Haan, secretary, University Copyright Office When I've been in the position to give, I've always tried to include the United Way. I like that the money stays in our community and helps local families. In 1979, my father was diagnosed with leukemia. Luckily, he had a good job that provided sick leave, but that wasn't enough to provide for a family of seven. We went through some really hard and lean times. At one point, my parents went to see about food stamps, but came home shortly after and said, "We'll just tighten our belts some more." They didn't even ask for help. "Because no matter how bad we have it, there are people out there in a lot worse shape." I'll never forget that or the help that we did receive. Our church brought over Christmas gifts and food and the Cancer Society provided gas money to help my dad get back and forth to Indianapolis for his treatments. That was a scary world to a 13-year-old, but knowing that there were people out there willing to help offered a little bit of relief. When you give to the United Way, you are helping someone locally, and that person might be able to give back some day. It's all a circle and it's good to be in a position to give. Becky Hershey, director of Purdue United Way With a young family and two full-time working parents, finding high-quality childcare is incredibly important. We discovered that the Lafayette Family YMCA provided child care at its facility as well as on site at the elementary school for before- and after-school care. They were a huge help to us in those early years for trustworthy, dependable care. When our youngest son received a life-changing medical diagnosis (he has epilepsy, a seizure disorder), we turned to our network of family and friends, and to the services provided through the United Way of Greater Lafayette. Due to his medical condition, he struggled academically, especially in reading and language arts. He became a "Read to Succeed" kid. Through this program, he was able to improve his reading skills by working with the volunteer on a weekly basis. Our family was able to experience firsthand the positive impact of the Read to Succeed program. It truly makes a difference! We give to the United Way because we have been given so much through the amazing work they do. Jaclyn Jones, payment card specialist, Office of Treasury Operations Giving to United Way has always been an important aspect of my life. I've seen firsthand how it can change someone's life for the better. I remember two years ago a woman was homeless and the Lafayette Transitional Housing helped to get her permanent housing and helped her find resources for other needs she had. Recently, I toured the Lafayette Transitional Housing facilities and witnessed just how helpful the program is to people. Volunteers come in and serve breakfast, lunch and dinner, and they also have programs to help people get into housing to start their journey to success. Lafayette Transitional Housing is one of the many excellent programs that United Way supports for our community. It is important to give back so others can succeed and be able to independently sustain their lives. Claudine Meilink, associate director of corporate outreach, Krannert Professional Development Center When I moved to West Lafayette nine years ago for my position at Purdue, I was the single mom of an 11-year-old son, and we had just moved 200 miles away from any family. Organizations supported by the United Way immediately helped us feel welcome in the Greater Lafayette community. In particular, my son attended the Boys & Girls Club after school. At that time, I was not able to afford child care, so this was a huge help. Now that I am in a better place financially, I want to pay it forward. My son also greatly benefited by being matched with a Big Brother, Alen, from Big Brothers Big Sisters of Greater Lafayette. At the time, Alen was a graduate student attending Purdue. He is someone that my son, Caleb, has stayed in touch with and continues to look to as a role model and mentor. This is why I give! For more information about United Way please feel free to watch this short video<https://www.youtube.com/watch?v=PNbuyvugQSY> or by visiting www.purdue.edu/unitedway<http://www.purdue.edu/unitedway>. Thank you, JoAnna JoAnna Hadley Account Clerk Forney Hall of Chemical Engineering, Room 1057 480 Stadium Mall Drive West Lafayette, IN 47907-2100 765-494-4072 Fax: 765-494-4073 hadleyj(a)purdue.edu<mailto:hadleyj@purdue.edu>

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EAPS Energy Colloquia by Prof. Anthony Ingraffea - Tuesday Oct. 27 at 7 PM
by Ewing, Virginia G 22 Oct '15

22 Oct '15

-----Original Message----- From: Robert L Nowack [mailto:nowack@purdue.edu] Sent: Thursday, October 22, 2015 2:00 PM To: Ewing, Virginia G Subject: EAPS Energy Colloquia by Prof. Anthony Ingraffea on Tuesday Oct. 27 at 7 PM Attached a flyer for an EAPS Energy Colloquia talk on Tuesday Oct. 27 at 7 PM in Physics Room 112. Presentation by Prof. Anthony Ingraffea from Cornell University who is one of the best known scientists/engineers analyzing many of the environmental concerns related to shale gas/oil exploration. The title of his talk will be, "The Science of Shale Gas/Oil: The Latest Evidence on Leaky Wells, Methane Emissions ,and Implications for Energy Policy. Please forward to any interested students and faculty in Chemical Engineering. Best Regards, Bob Nowack Dept. of EAPS nowack(a)purdue.edu 1-765-494-5978

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Annual reminders related to our School
by Farmus, Cristina D 21 Oct '15

21 Oct '15

For issues related to computers, network, computing labs, printers or printing quota please contact cheq(a)ecn.purdue.edu<mailto:cheq@ecn.purdue.edu>. For issues related to the building (heating, cooling, cleaning, security, moves, updates, maintenance, lights, etc.) or to request a key to an office or lab please email frnybldg(a)purdue.edu<mailto:frnybldg@purdue.edu>. To locate a piece of equipment check the College of Engineering equipment inventory located on the ChE intranet at https://engineering.purdue.edu/Intranet/Groups/Schools/ChE/EngineeringEquip…. To dispose of a piece of equipment contact frnybldg(a)purdue.edu<mailto:frnybldg@purdue.edu>. To make changes or post information to the ChE website or kiosk please email webmaster-che(a)ecn.purdue.edu<mailto:webmaster-che@ecn.purdue.edu>. Our School has a professional library with over 100 leadership, self-help and technical books. The list is available on the School intranet at https://engineering.purdue.edu/Intranet/Groups/Schools/ChE . To borrow a book or suggest other titles to be added to the library please let me know. Regards, Cristina Cristina Farmus Managing Director Chemical Engineering Purdue University 765 494 0027 cfarmus(a)purdue.edu<mailto:cfarmus@purdue.edu>

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