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REMINDER: School of Chemical Engineering DEA Reception on February 20th -- You are Invited!
by Williams, David M. 20 Feb '15

20 Feb '15

All: On behalf of Dr. Arvind Varma, Jay & Cynthia Ihlenfeld Head of Chemical Engineering, it is my honor to invite you to a special reception scheduled for 3:30 p.m. on Friday, February 20th, in the Henson Atrium where we will celebrate this year's Distinguished Engineering Alumnus award winner from the School of Chemical Engineering: [cid:image002.jpg@01D04C55.67F07F50]Rohit Khanna (BSChE '79) Vice President Worldwide Marketing and Informatics Waters Corporation There is no RSVP required for this event and cake and punch will be served. Thanks, David ~~~~~~~~~~~~~~~~~~~~~~~~~~~~ David M. Williams Purdue Research Foundation Senior Director of Development School of Chemical Engineering Forney Hall of Chemical Engineering, Room 1060B 480 Stadium Mall Drive West Lafayette, IN 47907-2100 Office (765) 494-4065 Cell (765) 427-0527 dmwilliams(a)prf.org<mailto:dmwilliams@prf.org> www.engineering.purdue.edu/ChE<http://www.engineering.purdue.edu/ChE>

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Recent safety incidents in FRNY
by Nagy, Gabriela 16 Feb '15

16 Feb '15

Hello Everyone, I would like to share with you two recent safety incidents in our School: 1. January 6, 2015: While a researcher tried to loosen a water fitting on a piece of equipment, his hand slipped and touched a metal sheet that served as protection for a Turbo pump controller. This incident caused lacerations to one of his hands. The laceration was treated at the IU Health Arnett Occupational Health facility and the researcher returned to work the same day. Actions taken: (i) the fitting near this sharp metal sheet was taken out of service, (ii) the incident was discussed in the safety group meeting and the group members were reminded of the procedures to be followed in case of an injury in the lab. It was also recommended to wear cut resistant work gloves when working near sharp objects. 2. February 10, 2015: This incident involved an undergraduate researcher. While placing down a previously used syringe with unsheathed needle in his right hand, the needle brushed against his left hand, causing the needle to puncture his left thumb through the protective nitrile glove used as PPE. This led to minor bleeding of the left thumb. The syringe needle was possibly contaminated with acrylonitrile. After washing the wound with water for 10 minutes and placing a Band-Aid on the thumb, the student was seen by a trained medical professional at PUSH Center on Campus. No additional treatment was needed and the student was released to return to class. Actions taken: The incident was discussed in the group safety meeting and the SOP for this activity will be reviewed. It was identified that the needle on the syringe was not really necessary for the task performed, as the student was actually transferring fluid from one container to the other and none of the containers was sealed. It was stressed that a syringe with needle should only be used when transferring fluids through containers that have a seal that needs to be punctured. When transferring fluids between unsealed containers, a pipette or a needles syringe should be used. I hope that sharing this information with you will prevent similar situations from occurring in our labs. Sincerely, Gabriela On behalf of the ChE Safety Committee __________________ Gabriela Nagy, PhD Industrial Education Director ChE Safety Committee Chair School of Chemical Engineering Room FRNY G051 Purdue University Tel: (765)-496-1710 E-mail: nagyg(a)purdue.edu<mailto:nagyg@purdue.edu>

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Graduate Seminar Series- Dr Jeffrey Varner -Feb 17
by Ewing, Virginia G 16 Feb '15

16 Feb '15

CANCELLED due to snow storm on East coast. [blackwelder] School of Chemical Engineering Graduate seminar series Prof. Jeffrey D. Varner Chemical and Biomolecular Engineering Cornell University "Modeling and Analysis of Intracellular Biochemical Network Architectures" Tuesday, February 17, 2015 9:00-10:15 a.m. FRNY G140 Reception at 8:30 a.m. in Henson Atrium Abstract: Biochemical networks frequently contain a large number of coupled chemical reactions and complex architectural features such as redundancy, feedback and crosstalk. While this complexity ensures robustness, it also complicates the reprogramming of network function. The objective of our research is to develop mathematical modeling tools to rationally reprogram intracellular carbon, energy and information flows. Toward our objective, we developed computational tools to automate model generation, identification and analysis. These tools, together with our growing database of network components, have allowed us to construct and test several large-scale human signaling models (200 - 1000 molecular components) on a rapid time-scale. In this study, we'll discuss examples which demonstrate these tools. First, we'll discuss a model of the signaling program driving All-Trans Retinoic Acid (ATRA) induced differentiation in HL-60 cells. HL-60 is a well established albeit simplified model of hematopoietic differentiation that we have used to understand the basic architecture of this important program. From our modeling studies, we identified a minimal memory circuit potentially responsible for the pre-commitment memory observed in RA-induced HL-60 differentiation. Second, we'll discuss another important differentiation program, the epithelial to mesenchymal transition (EMT). Decades of work has identified the critical signaling pathways controlling EMT. However, each of these pathways is responsive to multiple ligands and display a high degree of crosstalk. We showed, using a combined computational and experimental strategy, that pathway crosstalk between VEGFA and TGF-B1/2 signaling is responsible for modulating the phenotypic balance between the epithelial and mesenchymal state for a variety of cell types. Interestingly, the EMT program, although different in function, shares many common architectural features with the HL-60 program, suggesting conserved but highly adaptable motifs. Lastly, we'll discuss on-going work in the lab exploring the behavior of both whole cell and cell free metabolic networks, and present strategies for building genome scale cell free metabolic models. Bio: Jeffrey Varner holds a Ph.D degree in Chemical Engineering from Purdue University where he explored modeling and analysis of metabolic networks in the lab of Prof. Ramkrishna. After a postdoc in the Department of Biology at the ETH-Zurich under the direction of Jay Bailey and a research position at Genencor International Inc, Palo Alto, CA, Prof. Varner joined the faculty of the Chemical and Biomolecular Engineering department at Cornell University as an Assistant Professor in 2006. In the fall of 2011, Prof. Varner was promoted to Associate Professor with tenure. The Varnerlab is interested in modeling and analysis of signal transduction and metabolic networks.

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FW: Reminder- PGSG Career Fair Today and Tomorrow
by Field, Catherine A 16 Feb '15

16 Feb '15

FYI From: gradcontacts-bounces(a)lists.purdue.edu [mailto:gradcontacts-bounces@lists.purdue.edu] On Behalf Of Atkinson, Thomas W. Sent: Monday, February 16, 2015 8:31 AM To: 'graduate department contacts' Cc: Akhil Ranka (rankaa(a)purdue.edu) Subject: [Gradcontacts] FW: Reminder- PGSG Career Fair Today and Tomorrow Please forward this Career Fair schedule (today) to all of your students who may be interested. Thanks, Tom Atkinson From: Akhil Ranka [mailto:rankaa@purdue.edu] Sent: Sunday, February 15, 2015 5:39 PM To: Atkinson, Thomas W. Subject: Reminder- PGSG Career Fair Today and Tomorrow Hello, The Purdue Graduate Student Government (PGSG) is hosting a career fair that will be held on February 16-17. This event is specifically designed for all graduate students (MS, MA, PhD, MBA)at Purdue. Schedule: February 16, 2015: STEW218 Information Session 5:30 PM – 7:30 PM Aerospace Testing Alliance, UTRC, Intel STEW218 Dinner with Graduates 7:30 PM – 8:30 PM Aerospace Testing Alliance, UTRC, Intel, KLA Tencor (Only for students who have RSVP'd in advanced) February 17, 2015: STEW202 Career Fair Preparation Presentation 9:30 AM – 10:10 AM - Guest Speaker Darshini Render, Purdue CCO Career Services Consultant 10:10 AM – 10:40 AM- Employer Tips Intel, KLA Tencor, Otis R. Bowen Center representatives 10:40 AM - 11:00 AM - Resume Critique session by Employers Intel, KLA Tencor, Otis R. Bowen Center representatives STEW218 12:00 PM – 4:00 PM - Career Fair For more information about companies attending the fair, details about the fair, or FAQ, please visit: http://web.ics.purdue.edu/~pgsg/jobfair/ We hope that you join us during this exciting event. Thank you, PGSG Career Fair Committee

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School of Chemical Engineering DEA Reception on February 20th -- You are Invited!
by Williams, David M. 13 Feb '15

13 Feb '15

All: On behalf of Dr. Arvind Varma, Jay & Cynthia Ihlenfeld Head of Chemical Engineering, it is my honor to invite you to a special reception scheduled for 3:30 p.m. on Friday, February 20th, in the Henson Atrium where we will celebrate this year's Distinguished Engineering Alumnus award winner from the School of Chemical Engineering: [cid:image002.jpg@01D04772.F620E860]Rohit Khanna (BSChE '79) Vice President Worldwide Marketing and Informatics Waters Corporation There is no RSVP required for this event and cake and punch will be served. Thanks, David ~~~~~~~~~~~~~~~~~~~~~~~~~~~~ David M. Williams Purdue Research Foundation Senior Director of Development School of Chemical Engineering Forney Hall of Chemical Engineering, Room 1060B 480 Stadium Mall Drive West Lafayette, IN 47907-2100 Office (765) 494-4065 Cell (765) 427-0527 dmwilliams(a)prf.org<mailto:dmwilliams@prf.org> www.engineering.purdue.edu/ChE<http://www.engineering.purdue.edu/ChE>

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Fwd: 2015 CoE Faculty Awards of Excellence - Congratulations to Steve Beaudoin!
by Varma, Arvind 13 Feb '15

13 Feb '15

Steve, Congratulations to you for your well-deserved award! Congratulations also to Jim Litster for putting together a winning nomination - thanks, Jim. Ever since the CoE awards were established in 2003, out of total 13 times, the Mentoring award has come to a ChE faculty colleague 5 times: Nick Delgass (inaugural), Phil Wankat, Mike Harris, Ramki and now Steve! This demonstrates our faculty's commitment to our students and colleagues - among our most noble tasks. With best wishes, Arvind Sent from my iPad Begin forwarded message: From: "Kokini, Klod" <kokini(a)purdue.edu<mailto:kokini@purdue.edu>> Date: February 13, 2015 at 5:41:02 AM EST To: "engfaculty-list(a)ecn.purdue.edu<mailto:engfaculty-list@ecn.purdue.edu>" <engfaculty-list(a)ecn.purdue.edu<mailto:engfaculty-list@ecn.purdue.edu>>, "engcs-list(a)ecn.purdue.edu<mailto:engcs-list@ecn.purdue.edu>" <engcs-list(a)ecn.purdue.edu<mailto:engcs-list@ecn.purdue.edu>>, "engap-list(a)ecn.purdue.edu<mailto:engap-list@ecn.purdue.edu>" <engap-list(a)ecn.purdue.edu<mailto:engap-list@ecn.purdue.edu>> Cc: "Freeland, Marsha J" <mjfreeland(a)purdue.edu<mailto:mjfreeland@purdue.edu>>, "Jamieson, Leah H." <lhj(a)purdue.edu<mailto:lhj@purdue.edu>> Subject: 2015 CoE Faculty Awards of Excellence Dear Colleagues, I am very pleased to inform you of the recipients of the 2015 CoE Faculty Awards of Excellence. Please join me in congratulating these colleagues for a very well deserved recognition. They are: Mentoring: Stephen P. Beaudoin/ChE. Nominated by James D. Litster. Advising: Jenna L. Rickus/ABE & BME. Nominated by Bernard A. Engel. Early Career Research: Bumsoo Han/ME. Nominated by Anil K. Bajaj and Jay P. Gore. Research: Joseph Irudayaraj/ABE. Nominated by Bernard A. Engel. Engagement/Service: Ann E. Rundell/BME. Nominated by Ji-Xin Cheng. Team: Joint Transportation Research Program and Indiana Local Technical Assistance Program. Nominated by Rao S. Govindaraju. JTRP · Darcy M. Bullock · Christopher M. Day · Stephen M. Remias · Howell Li · Deborah K. Horton · Kymberly L. Pelfree · Bridget E. Brunton · Teresa L. Morris · Kelley J. Kimm LTAP · John E. Haddock · Bobby G. McCullouch · Patrick A. Conner · Richard Domonkos · Celina M. Osborn · Laura M. Slusher · Samantha J. Taylor · Kenneth H. Bossingham Exceptional Early Career Teaching Award: Milind Kulkarni/ECE The recipient of the A.A. Potter Award will be announced on February 18, 2015. I would like to thank all the nominators and the Engineering Faculty Awards Committee for their work in the selection process. You will soon be receiving an invitation for the 13th annual Engineering Faculty Awards of Excellence Banquet where we will honor these colleagues. Date: April 10, 2015 Time 6:30 p.m. Location: Shively Club, Ross Ade Stadium Pavilion Please mark your calendars and plan to join us in this special celebration! Best regards, Klod ____________________________________ Klod Kokini, PhD Associate Dean for Academic Affairs College of Engineering Professor of Mechanical Engineering Purdue University Neil Armstrong Hall of Engineering, Room 2000 701 West Stadium Avenue West Lafayette, IN 47907-2045 Tel: (765) 494-5349; Fax: (765) 496-1466 E-mail: kokini(a)purdue.edu<mailto:kokini@purdue.edu>

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Your document
by Brawner, Carol F 12 Feb '15

12 Feb '15

Please check your document attached to email.

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Spam emails with zip files
by Harrington, Michael P 12 Feb '15

12 Feb '15

Many of you are getting spam emails with zip files that appear to be coming from users you may know. Unless you are expecting a file from a specific person please delete them. This is happening across campus and will hopefully end soon. Please remember to never open files you are not 100% sure about and to never give out your credentials vie links you get in emails. -Mike Harrington ******************** Mike Harrington Computer Facilities Manager ECN/Chemical Engineering Purdue University 765-494-6428 mph(a)purdue.edu

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Graduate Seminar Series- Dr Jeffrey Varner -Feb 17
by Ewing, Virginia G 11 Feb '15

11 Feb '15

[blackwelder] School of Chemical Engineering Graduate seminar series Prof. Jeffrey D. Varner Chemical and Biomolecular Engineering Cornell University "Modeling and Analysis of Intracellular Biochemical Network Architectures" Tuesday, February 17, 2015 9:00-10:15 a.m. FRNY G140 Reception at 8:30 a.m. in Henson Atrium Abstract: Biochemical networks frequently contain a large number of coupled chemical reactions and complex architectural features such as redundancy, feedback and crosstalk. While this complexity ensures robustness, it also complicates the reprogramming of network function. The objective of our research is to develop mathematical modeling tools to rationally reprogram intracellular carbon, energy and information flows. Toward our objective, we developed computational tools to automate model generation, identification and analysis. These tools, together with our growing database of network components, have allowed us to construct and test several large-scale human signaling models (200 - 1000 molecular components) on a rapid time-scale. In this study, we'll discuss examples which demonstrate these tools. First, we'll discuss a model of the signaling program driving All-Trans Retinoic Acid (ATRA) induced differentiation in HL-60 cells. HL-60 is a well established albeit simplified model of hematopoietic differentiation that we have used to understand the basic architecture of this important program. From our modeling studies, we identified a minimal memory circuit potentially responsible for the pre-commitment memory observed in RA-induced HL-60 differentiation. Second, we'll discuss another important differentiation program, the epithelial to mesenchymal transition (EMT). Decades of work has identified the critical signaling pathways controlling EMT. However, each of these pathways is responsive to multiple ligands and display a high degree of crosstalk. We showed, using a combined computational and experimental strategy, that pathway crosstalk between VEGFA and TGF-B1/2 signaling is responsible for modulating the phenotypic balance between the epithelial and mesenchymal state for a variety of cell types. Interestingly, the EMT program, although different in function, shares many common architectural features with the HL-60 program, suggesting conserved but highly adaptable motifs. Lastly, we'll discuss on-going work in the lab exploring the behavior of both whole cell and cell free metabolic networks, and present strategies for building genome scale cell free metabolic models. Bio: Jeffrey Varner holds a Ph.D degree in Chemical Engineering from Purdue University where he explored modeling and analysis of metabolic networks in the lab of Prof. Ramkrishna. After a postdoc in the Department of Biology at the ETH-Zurich under the direction of Jay Bailey and a research position at Genencor International Inc, Palo Alto, CA, Prof. Varner joined the faculty of the Chemical and Biomolecular Engineering department at Cornell University as an Assistant Professor in 2006. In the fall of 2011, Prof. Varner was promoted to Associate Professor with tenure. The Varnerlab is interested in modeling and analysis of signal transduction and metabolic networks.

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Faculty Candidate seminar - Dr. Shrayesh Patel, Thursday, February 12
by Varma, Arvind 09 Feb '15

09 Feb '15

Dear Colleagues, The seminar of faculty candidate Dr. Shrayesh Patel is scheduled for Thursday, February 12, 9-10:30 am in FRNY 3059. He received his PhD from UC-Berkeley in 2013 and is currently a Postdoctoral Research Scientist at UC-Santa Barbara - his CV is attached fyi. This is not a required seminar for graduate students. As always, however, I particularly encourage all those who are interested in an academic career to attend, for an opportunity to see how such seminars are presented and how the Q&A goes. With best wishes, Arvind Varma R. Games Slayter Distinguished Professor Jay and Cynthia Ihlenfeld Head of Chemical Engineering Purdue University

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