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LAST CHANCE TO REGISTER with fees waived - EMBRIO SUMMER WORKSHOPS AND RESEARCH SYMPOSIUM
by Brent Thomas Ladd 05 Jun '26

05 Jun '26

Dear EMBRIO Members: 👉 LAST CHANCE TO REGISTER, TODAY, JUNE 5TH : EMBRIO SUMMER WORKSHOPS AND RESEARCH SYMPOSIUM – JUNE 22-25, UNIVERSITY OF NOTRE DAME CAMPUS. Register TODAY June 5th to secure your hotel room at Morris Inn on Notre Dame campus and have workshop and symposium fees waived. After Today June 5th you will be charged full registration fees, and on your own for hotel arrangements and costs. Registration<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fweb.cvent…> * Symposium Schedule (Tentative Schedule-at-a-glance<https://www.purdue.edu/research/embrio/research/Schedule-at-a-glance_Advanc…>) * Speakers (PDF Speaker Booklet<https://www.purdue.edu/research/embrio/research/Featured-Speaker-Brochure2.…>) - Featured Speakers: Mark Alber (UC-R), Sharon Gerecht (Duke), Ed Munro (UChicago), Noah Mitchell (UChicago), Mary Mullins (UPenn), Jitao Zhang (MSU). - Lightning Talks by EMBRIO Postdocs and Research Scientists: Nilay Kumar, Linlin Li, Maria Unger, Shulan Xiao, Weiwei Zhang - Science of Imaging Innovators Panel * Research Poster Session (Submit Abstracts no later than June 7th). Online abstract submission site<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca…>. Thanks, Brent Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering, Purdue University Office: Hall for Discovery Learning and Research, Ste. 203 207 S. Martin Jischke Drive West Lafayette, IN 47907 laddb(a)purdue.edu

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New EMBRIO paper out + reminders
by Brent Thomas Ladd 04 Jun '26

04 Jun '26

Dear EMBRIOnic People, New Paper in Nature Nanotechnology Check out groundbreaking work from the Krishna Jayant<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.linke…> lab with a paper led by Shulan Xiao<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.linke…> sharing insights and methods enabling a minimally invasive new class of biohybrid electronic interfaces, in which the recording element is not a foreign probe inserted from outside but a biocompatible molecular structure that becomes part of the membrane itself! https://www.nature.com/articles/s41565-026-02180-7<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.natur…> 👉 EMBRIO Investigators: A reminder that Y5/final reports are due July 1st (see individual email from me May 28th with details) 👉 LAST DAY TO REGISTER, JUNE 5TH : EMBRIO SUMMER WORKSHOPS AND RESEARCH SYMPOSIUM – JUNE 22-25. Register by tomorrow, Friday, June 5th to secure your hotel room at Morris Inn on Notre Dame campus. After this date you will be on your own for hotel arrangements and costs. Registration<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fweb.cvent…> * Symposium Schedule (Tentative Schedule-at-a-glance<https://www.purdue.edu/research/embrio/research/Schedule-at-a-glance_Advanc…>) * Speakers (PDF Speaker Booklet<https://www.purdue.edu/research/embrio/research/Featured-Speaker-Brochure2.…>) - Featured Speakers: Mark Alber (UC-R), Sharon Gerecht (Duke), Ed Munro (UChicago), Noah Mitchell (UChicago), Mary Mullins (UPenn), Jitao Zhang (MSU). - Lightning Talks by EMBRIO Postdocs and Research Scientists: Nilay Kumar, Linlin Li, Maria Unger, Shulan Xiao, Weiwei Zhang - Science of Imaging Innovators Panel * Research Poster Session (Submit Abstracts no later than June 7th). Online abstract submission site<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca…>. Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering, Purdue University Office: Hall for Discovery Learning and Research, Ste. 203 207 S. Martin Jischke Drive West Lafayette, IN 47907 laddb(a)purdue.edu

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EMBRIO Events Last Day to Register: June 5th
by Brent Thomas Ladd 01 Jun '26

01 Jun '26

Dear EMBRIO Members, Three-week countdown until our Symposium and Workshops<https://www.purdue.edu/research/embrio/research/jointsymposium.php> June 22nd - 25th (promotional poster attached) links below. Register<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fweb.cvent…> before end of business this Friday, June 5th; hotel room block at Morris Inn on Notre Dame campus only guaranteed through June 5th. Research Posters online abstract submission site<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca…> - deadline of June 7th. All are encouraged to present research posters. Those who have already registered will receive a follow-up email this week. Brent ________________________________ 👉LAST DAY TO REGISTER, JUNE 5TH : EMBRIO SUMMER WORKSHOPS AND RESEARCH SYMPOSIUM – JUNE 22-25. Please register Friday, June 5th to secure your hotel room at Morris Inn on Notre Dame campus. After this date you will be on your own for hotel arrangements and costs. Registration<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fweb.cvent…> * Symposium Schedule (Tentative Schedule-at-a-glance<https://www.purdue.edu/research/embrio/research/Schedule-at-a-glance_Advanc…>) * Speakers (PDF Speaker Booklet<https://www.purdue.edu/research/embrio/research/Featured-Speaker-Brochure2.…>) - Featured Speakers: Mark Alber (UC-R), Sharon Gerecht (Duke), Ed Munro (UChicago), Noah Mitchell (UChicago), Mary Mullins (UPenn), Jitao Zhang (MSU). - Lightning Talks by EMBRIO Postdocs and Research Scientists: Nilay Kumar, Linlin Li, Maria Unger, Shulan Xiao, Weiwei Zhang - Science of Imaging Innovators Panel (TBA) * Research Poster Session (Submit Abstracts no later than June 7th). Online abstract submission site<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca…>. [cid:c3f34cc4-69fb-4c7c-843d-d497c87164f0] [cid:84f6f8e7-0633-4fa6-ab32-2802a46ba05e][cid:90dbea2c-0657-40ee-9f5d-bbadc3ee782d][cid:0ac0fe3c-6945-4e24-bd50-ed19a89b632b] Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering, Purdue University Office: Hall for Discovery Learning and Research, Ste. 203 207 S. Martin Jischke Drive West Lafayette, IN 47907 laddb(a)purdue.edu

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Early Reg Ends Today EMBRIO Workshops and Symposium
by Brent Thomas Ladd 22 May '26

22 May '26

Dear EMBRIO Members, Reminders: Register<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fweb.cvent…> today for EMBRIO summer events<https://www.purdue.edu/research/embrio/research/jointsymposium.php>; hotel room block at Morris Inn on Notre Dame campus only guaranteed through today; Poster abstract submission is open - deadline of June 7th. All are encouraged to present research posters. Wishing everyone a relaxing, enjoyable Memorial Day holiday<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fen.wikipe…> <https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fen.wikipe…> weekend, Brent 👉REGISTER NOW - EARLY REG Ends Today MAY 22nd: EMBRIO SUMMER WORKSHOPS AND RESEARCH SYMPOSIUM – JUNE 22-25. Please register by today to secure your hotel room at Morris Inn on Notre Dame campus ! Registration<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fweb.cvent…> * Symposium Schedule (Tentative Schedule-at-a-glance<https://www.purdue.edu/research/embrio/research/Schedule-at-a-glance_Advanc…>) * Speakers (PDF Speaker Booklet<https://www.purdue.edu/research/embrio/research/Featured-Speaker-Brochure2.…>) - Featured Speakers: Mark Alber (UC-R), Sharon Gerecht (Duke), Ed Munro (UChicago), Noah Mitchell (UChicago), Mary Mullins (UPenn), Jitao Zhang (MSU). - Lightning Talks: Nilay Kumar, Linlin Li, Maria Unger, Shulan Xiao, Weiwei Zhang - Science of Imaging Innovators Panel (TBA) * Research Poster Session (Submit Abstracts no later than June 7th). Online abstract submission site<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca…>. [cid:0ca2ede7-5b3b-4f94-b3c8-7a0a4086616f] [cid:ae9b0184-e7f8-46de-af7c-260e6f1eca75][cid:dd5a4686-1d8d-483e-a799-0b4dd3c15f93][cid:8e2c5cec-59fa-4b64-b92d-97ccb2c39aa9] Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering, Purdue University Office: Hall for Discovery Learning and Research, Ste. 203 207 S. Martin Jischke Drive West Lafayette, IN 47907 laddb(a)purdue.edu

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Research talks today 3pm; Reg this week for symposium and workshops!
by Brent Thomas Ladd 18 May '26

18 May '26

[cid:1cc3e2d5-21c1-44d5-8115-6df3fef07ce3] Dear EMBRIO Community, Details on research updates this afternoon at 3 EDT; Registration push this week for our summer workshops and symposium (research poster abstracts upload is open, due by June 7th). 👀 EMBRIO RESEARCH UPDATES FROM THRUST 1 AND 4 – TODAY 3PM EDT: ZOOM<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-ed…> Plan to join us this afternoon at 3PM EDT when we will feature research updates from the Gardner Lab in Thrust 4, followed by collaborative research in Thrust 1 from the Kinzer-Ursem (1A) + Evans (1B) Labs. 👉REGISTER NOW - EARLY REG Extended to MAY 22nd: EMBRIO SUMMER WORKSHOPS AND RESEARCH SYMPOSIUM – JUNE 22-25. Please register this week! Registration<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fweb.cvent…> * Symposium Schedule (Tentative Schedule-at-a-glance<https://www.purdue.edu/research/embrio/research/Schedule-at-a-glance_Advanc…>) * Speakers (PDF Speaker Booklet<https://www.purdue.edu/research/embrio/research/Featured-Speaker-Brochure2.…>) - Featured Speakers: Mark Alber (UC-R), Sharon Gerecht (Duke), Ed Munro (UChicago), Noah Mitchell (UChicago), Mary Mullins (UPenn), Jitao Zhang (MSU). - Lightning Talks: Nilay Kumar, Linlin Li, Maria Unger, Shulan Xiao, Weiwei Zhang - Science of Imaging Innovators Panel (TBA) * Research Poster Session (Submit Abstracts no later than June 7th). Online abstract submission site<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca…>. [cid:1523e417-8145-48ad-b4b6-ed1d5d99b634] [cid:5d0b9064-0c07-428b-968f-e9f1a8f21642][cid:c09ceab6-3b32-418b-89a0-84dbd1793520][cid:f76958d8-785a-43d2-84e5-6ba43d0c28ec] Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering, Purdue University Office: Hall for Discovery Learning and Research, Ste. 203 207 S. Martin Jischke Drive West Lafayette, IN 47907 laddb(a)purdue.edu

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REG Now for EMBRIO Symposium + Wkshops, Join Monday Thrust 1 and 4 talks
by Brent Thomas Ladd 15 May '26

15 May '26

Dear EMBRIO Community, 👀 EMBRIO RESEARCH UPDATES FROM THRUST 1 AND 4 – MAY 18TH: ZOOM<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-ed…> Plan to join us next Monday at 3PM EDT when we will feature research updates with a presentation from the Gardner Lab in Thrust 4, and a presentation from collaborative research in Thrust 1 from the Kinzer-Ursem + Evans Labs. 👉REGISTER NOW - EARLY REG ENDS MAY 18TH: EMBRIO SUMMER WORKSHOPS AND RESEARCH SYMPOSIUM – JUNE 22-25. FEATURED SPEAKERS ADDED (SEE ATTACHED BROCHURE, AND EVENTS POSTER) [cid:a0fa5b5f-c717-4c48-b27e-b11e3186246d] Early registration is open<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fcvent.me%…> through May 18th for our joint summer school workshops and symposium. (Schedule at the event website<https://www.purdue.edu/research/embrio/research/jointsymposium.php>). This will be an opportunity to increase your skills in employing AI in research, increase your image analysis tool kit, and team up to create new methods and tools, as well as engage with a network of leading scientists and engineers with room for all to present their research. We are working on finalizing speakers, keynotes, panel and poster sessions for the symposium in the next few days and will have a complete schedule to share soon. Workshop details are available at the website. There will be coordinated travel option between Purdue and Notre Dame. *Please note that we are asking EMBRIO attendees to chip in a $15 registration fee to cover materials (incl. event T-shirt). If you have any issues or questions regarding the registration process, please contact Kaylee Wolf at Notre Dame (kwolf5(a)nd.edu<mailto:kwolf5@nd.edu> ). Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering, Purdue University Office: Hall for Discovery Learning and Research, Ste. 203 207 S. Martin Jischke Drive West Lafayette, IN 47907 laddb(a)purdue.edu

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EMBRIO News and Upcoming Events
by Brent Thomas Ladd 11 May '26

11 May '26

[cid:7fc5fa9c-35d7-419b-94d4-7f8ae15e45ec] Dear EMBRIOnic People, 👉REGISTER NOW: EMBRIO SUMMER WORKSHOPS AND RESEARCH SYMPOSIUM – JUNE 22-25 [cid:6096ab05-cc35-442f-9985-b5a2280ae2c4] Early registration is open<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fcvent.me%…> through May 18th for our joint summer school workshops and symposium (event website<https://www.purdue.edu/research/embrio/research/jointsymposium.php>). This will be an opportunity to increase your skills in employing AI in research, increase your image analysis tool kit, and team up to create new methods and tools, as well as engage with a network of leading scientists and engineers with room for all to present their research. We are working on finalizing speakers, keynotes, panel and poster sessions for the symposium in the next few days and will have a complete schedule to share soon. Workshop details are available at the website. There will be coordinated travel option between Purdue and Notre Dame. *Please note that we are asking EMBRIO attendees to chip in a $15 registration fee to cover materials (incl. event T-shirt). If you have any issues or questions regarding the registration process, please contact Kaylee Wolf at Notre Dame (kwolf5(a)nd.edu<mailto:kwolf5@nd.edu> ). 👀 EMBRIO RESEARCH UPDATES – MAY 18TH: ZOOM<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-ed…> Plan to join us next Monday at 3PM EDT when we will feature research updates with a presentation from the Gardner Lab in Thrust 4, and a presentation from collaborative research in Thrust 1 from the Kinzer-Ursem + Evans Labs. ‼️EMBRIO PAPER MODELING EVL CHANGES AND EXTERNAL FORCES DURING ZEBRAFISH EPIBOLY Congratulations to Sharon Minsuk, lead author, and all co-authors on the recent npj Systems Biology and Applications paper featuring the Modeling epithelial deformation and cell rearrangement in response to external forces during Zebrafish epiboly<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.natur…>. EMBRIO labs involved include Glazier, Mullins, and Umulis, along with T.J. Sego (now at U of FL). Collaborating with the team, Sharon constructed an agent-based model of the enveloping layer (EVL) during epiboly and its response to exogenous forces using a center-based simulation framework (Tissue Forge, developed by the Glazier lab). Their model captures the large viscoelastoplastic deformation of the EVL by cell rearrangement, and accommodates the required cell neighbor exchanges without losing mechanical integration. This is a major accomplishment. Learn more at the online article<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.natur…>. [Fig. 11: Rate of EVL edge straightening correlates negatively with the strength of the bond angle constraint as applied to leading edge bond transformations.] Fig. 11: Rate of EVL edge straightening correlates negatively with the strength of the bond angle constraint as applied to leading edge bond transformations. Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering, Purdue University Office: Hall for Discovery Learning and Research, Ste. 203 207 S. Martin Jischke Drive West Lafayette, IN 47907 laddb(a)purdue.edu

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EMBRIO Summer Symposium and Workshops: Registration is open!
by Brent Thomas Ladd 04 May '26

04 May '26

[cid:50b39ac2-e7ea-4249-ace9-04c0aa7c041d] EMBRIO Members, 👉Registration link, draft schedule, and details are available for our summer workshops and joint symposium - early registration is encouraged through May 18th: https://www.purdue.edu/research/embrio/research/jointsymposium.php Note: additional speakers and final schedule will be announced soon. [cid:3214ad36-16ab-4536-a581-d1f83c204700]<https://www.purdue.edu/research/embrio/research/jointsymposium.php> Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering, Purdue University Office: Hall for Discovery Learning and Research, Ste. 203 207 S. Martin Jischke Drive West Lafayette, IN 47907 laddb(a)purdue.edu

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Registration is Open! EMBRIO Advancing Morphogenetic Biosciences & Bioengineering Symposium + Workshops
by Brent Thomas Ladd 30 Apr '26

30 Apr '26

[cid:7de27ec6-cd3e-42b8-aef1-41ee5d070951] EMBRIO Members, 👉Registration link, draft schedule, and details are available for our summer workshops and joint symposium - early registration is encouraged through May 18th: https://www.purdue.edu/research/embrio/research/jointsymposium.php Note: additional speakers and final schedule will be announced soon. [cid:a6d300d5-fca2-4df9-a572-58762c112cfb]<https://www.purdue.edu/research/embrio/research/jointsymposium.php> Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering, Purdue University Office: Hall for Discovery Learning and Research, Ste. 203 207 S. Martin Jischke Drive West Lafayette, IN 47907 laddb(a)purdue.edu

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Upcoming Events + New Publications
by Brent Thomas Ladd 21 Apr '26

21 Apr '26

[cid:9b95e19f-46ea-47b2-8bad-38318bde808e] Dear EMBRIOnic People, Thanks to the Zartman Lab members and Magana Lab members for presenting research updates yesterday. You can access the videos and associated meeting documents on our shared Box account in the All-Hands Meeting Recordings folder<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fapp.box.c…>. We will be back on May 18th for research presentations from Thrust 4 with the Gardner Lab, and Thrust 1 with the Kinzer-Ursem Lab + Evans Lab. EMBRIO JOINT SYMPOSIUM + WORKSHOPS The website for our summer events Advancing Morphogenetic Biosciences & Bioengineering Symposium + Workshops<https://www.purdue.edu/research/embrio/research/jointsymposium.php> is now live. Please continue to hold your week of June 22nd - schedules, speakers, registration, travel, and lodging details will be available very soon. * Symposium on June 25th * Mini-workshops June 22nd: * AI Applications for Biological Image Analysis and Parameter Optimization * From Pixels to Pipelines: Practical Image Analysis with Fiji/ImageJmini-workshop. * Two-day team-based workshop June 23rd-24th * Tools-4-Cells & Tissues (T4CT) Design Challenge Workshop. CHICAGO CYTOSKELETON MEETING The next Chicago Cytoskeleton Meeting is coming up on Friday May 1st at Loyola University Chicago Water Tower Campus. This includes selected trainee talks, keynote by Dr. Dyche Mullins, poster session, and social. Please register and sign-up for a poster spot on the website<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fsites.goo…>. Poster sign-ups are due next Wednesday, April 22nd. Note that registration is free. NEW PUBLICATIONS Congrats to the Jayant Lab, and EMBRIO members Shulan Xiao and Krishna Jayant with co-authors on two recent publications highlighted here: Blood-catalyzed n-doped polymers for reversible optical neural control. Science. Samal S, Xiao S, Nelson S, Kolhe O, Khan HF, Habibi Matin M, Lee W-J, Ahmed M, Wang D, Wang T, Pikes T, N. Scott, A, Alejandra Rodriguez, J, R. Olson, M, Deng, Q, I. Parkinson, E, Rochet, JC, Jayant, K, and Mei, J. Blood-catalyzed n-doped polymers for reversible optical neural control. Science. 2026;392(6793):eadu5500. DOI:10.1126/science.adu5500<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2…> [https://www.science.org/cms/10.1126/science.adu5500/asset/640a7a54-b8c2-47d…] * Biology as a Fabrication Engine for Neural Interfaces This work demonstrates that endogenous blood chemistry can catalyze the formation of functional n‑doped conducting polymers directly in living tissue, eliminating the need for rigid implants or exogenous catalysts. For EMBRIO, this represents a paradigm shift toward bio‑assembled, self‑integrating materials as a foundational strategy for neural engineering. * Reversible, Nongenetic Optical Neuromodulation The in situ–formed polymers enable millisecond‑scale, reversible optical suppression of neural activity without genetic modification. Neural control arises through thermo‑ionic shunting and altered ion channel excitability, highlighting a soft, analog modality of neuromodulation aligned with EMBRIO’s emphasis on minimally invasive control of biological systems. * Scalable Pathway Toward Translational Bioelectronics By leveraging ubiquitous biological components (blood, light) and avoiding permanent hardware, the platform offers a generalizable and potentially scalable route to clinical neuromodulation. This directly supports EMBRIO’s mission to bridge fundamental materials science with deployable bioelectronic medicine. Mild focal cooling decouples dendrites to reconfigure cortical output. Advanced Science Habibi Matin M, Xiao S, Jayant K. Mild focal cooling decouples dendrites to reconfigure cortical output. Advanced Science. 2026. DOI: https://doi.org/10.1002/advs.202520773<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2…> [Details are in the caption following the image] * Dendrites as Primary Targets for Circuit Reconfiguration The study shows that mild, focal cooling (~4 °C) selectively disrupts dendritic–somatic coupling—especially in apical tufts—without silencing neurons outright. This reframes neuromodulation as control over subcellular computation, a key EMBRIO concept linking physics to function. * Thermal Gradients Enable Analog Control of Neural Output Rather than acting as a global suppressor, cooling introduces graded, compartment‑specific changes in excitability, leading to reconfigured cortical output patterns. This establishes temperature as a precision biophysical control variable, complementary to electrical or optical approaches championed by EMBRIO. * Non‑Destructive, Reversible Modulation of Brain Computation The effects are rapid and reversible, preserving baseline circuit integrity while transiently altering information flow. For EMBRIO, this highlights energy‑efficient, non‑destructive strategies to probe and control neural systems across scales—from dendrites to behavior. Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering, Purdue University Office: Hall for Discovery Learning and Research, Ste. 203 207 S. Martin Jischke Drive West Lafayette, IN 47907 laddb(a)purdue.edu

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