- Embrio-list - ecn.purdue.edu

EMBRIO Weekly Update 3 PM Today
by Brent T Ladd 19 Sep '22

19 Sep '22

Hello EMBRIO Members, Today at 3 pm we'll have research presentations by Juana Mendenhall's Lab and Deva Chan's Lab Zoom link: https://purdue-edu.zoom.us/j/96053485465?pwd=elVnY20wcm9kaFRtVUdPcmFHaGl1UT… Reminder: Please complete the very brief online survey for participation in the NSF BII Annual Meeting hosted by BII NSF Program Directors taking place online October 18 - 19. https://purdue.ca1.qualtrics.com/jfe/form/SV_9KpbIbln6tkQ84u NSF Program Directors have requested broad participation of faculty, students, postdocs, and staff in the upcoming BII NSF Annual Meeting, and have especially requested we have at least one representative attend each of the 8 breakout sessions during 2-3pm Tuesday Oct. 18. And, to nominate student or postdoc led posters to be presented early afternoon Wednesday Oct. 19. Breakout Session Topics: 1: Running a complex project 2: Creating an institute culture 3: Data management and data access 4: Integration challenges 5: Integration through modeling 6: Project evaluation 7: Promoting early career advancement 8: Enhancing diversity, equity, and inclusion Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering Purdue University laddb(a)purdue.edu <https://www.purdue.edu/research/embrio/>

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EMBRIO announcements - sign up for BII NSF meeting
by Brent T Ladd 16 Sep '22

16 Sep '22

Hello There EMBRIO Members, A few announcements - please sign up for NSF BII Annual Meeting participation below. Thanks, Brent A. Details on participation in the NSF BII Annual Meeting B. Monday's Weekly Update C. National Postdoc Appreciation Week September 19-23 A. Details on participation in the NSF BII Annual Meeting Our BII NSF Program Directors have requested broad participation of faculty, students, postdocs, and staff in the upcoming BII NSF Annual Meeting taking place online October 18 - 19. Attached is a draft schedule of events. NSF Program Directors have especially requested our Institute have at least one representative attend each of the 8 breakout sessions during 2-3pm Tuesday Oct. 18. And, to nominate student or postdoc led posters to be presented early afternoon Wednesday Oct. 19. Breakout Session Topics: 1: Running a complex project 2: Creating an institute culture 3: Data management and data access 4: Integration challenges 5: Integration through modeling 6: Project evaluation 7: Promoting early career advancement 8: Enhancing diversity, equity, and inclusion Please complete the web-based survey to indicate your participation: https://purdue.ca1.qualtrics.com/jfe/form/SV_9KpbIbln6tkQ84u B. Monday's Weekly Update, September 19, 3pm. Presentations by Juana Mendenhall's Lab and Deva Chan's Lab Zoom: https://purdue-edu.zoom.us/j/96053485465?pwd=elVnY20wcm9kaFRtVUdPcmFHaGl1UT… C. National Postdoc Appreciation Week September 19-23 The National Postdoctoral Assocation is promoting a weeklong appreciation of postdocs with useful online professional development and support sessions. Check out the offerings: https://www.nationalpostdoc.org/page/2022NPAW A shoutout to all EMBRIO postdocs. Your research and leadership in the Institute moves us forward. Our postdocs by name below (apologies if I've left anyone out, let me know): Purdue PostDoc Aishwarya Pawar Purdue PostDoc Aritra Chatterjee Indiana PostDoc Hayden Fennell Penn PostDoc Joe Zinski Purdue PostDoc Norma Perez Indiana PostDoc Sharon Minsuk Indiana PostDoc TJ Sego Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering Purdue University laddb(a)purdue.edu <https://www.purdue.edu/research/embrio/>

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Today's EMBRIO Weekly Update at 3
by Brent T Ladd 12 Sep '22

12 Sep '22

Dear EMBRIO Members, See you at today's EMBRIO Weekly Update Zoom meeting starting at 3 with an overview of the CUREs program opportunity from Stephanie Gardner followed by research talks from Qing Deng's Lab (Shelly Tan and Chang Ding), and GuangJun Zhang's Lab (Ziyu Dong). Zoom link: https://purdue-edu.zoom.us/j/96053485465?pwd=elVnY20wcm9kaFRtVUdPcmFHaGl1UT… Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering Purdue University laddb(a)purdue.edu <https://www.purdue.edu/research/embrio/>

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EMBRIO Weekly Update 9/12
by Brent T Ladd 09 Sep '22

09 Sep '22

Dear EMBRIO Members, We're looking forward to Monday's Zoom meeting where we'll hear from Qing Deng's Lab (Shelly Tan and Chang Ding), and GuangJun Zhang's Lab, along with an overview of the CUREs program from Stephanie Gardner (see below for the opportunity). Zoom link: https://purdue-edu.zoom.us/j/96053485465?pwd=elVnY20wcm9kaFRtVUdPcmFHaGl1UT… Reminder: RESEARCH & EDUCATION INTEGRATION: CUREs PROGRAM OPPORTUNITY Want to broaden access to undergraduate research experiences in integrative biology? CUREs could be an answer! Course-based Undergraduate Research Experiences (CUREs) are a way to allow more and diverse students the opportunity to experience research by embedding real research projects into courses students might take as part of their normal coursework. CUREs can be a full-semester course in which the focus is the work on the research project, or they can be a multi-week research module embedded within a course. Stephanie Gardner has worked with instructors in one-on-one or in cohort models to train and support them as they develop and teach CUREs. Within the EMBRIO Institute engaging students in interdisciplinary research is a priority, incorporating imaging, simulation and computation, as relevant to the project. Stephanie is excited to work with interested EMBRIO graduate students, postdocs, research scientists, and faculty on CUREs. To gauge interest and help with planning, please complete this brief interest survey by September 23rd: https://purdue.ca1.qualtrics.com/jfe/form/SV_29tas2RkBAA5e8S Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering Purdue University laddb(a)purdue.edu <https://www.purdue.edu/research/embrio/>

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EMBRIO NEWS
by Brent T Ladd 07 Sep '22

07 Sep '22

[cid:c2b1f583-746d-4564-861d-ee151c016319] “EMBRIO NEWS” : Cast your vote<https://poll-maker.com/QT52V51Y4> on submitted newsletter name ideas September 7, 2022 DIRECTORS NOTE Hello EMBRIO Community! These last few weeks have been a whirlwind with our NSF annual report due and getting year two budget requests in, all overlapping with the start of Fall semester. A huge thank you to everyone for your timely submissions of progress reports, requests, and responses that have allowed the Directors to meet the deadlines of our funding sponsor, NSF. You will find a bit more about our inaugural annual report in the Institute Spotlight, as well as a heads-up for an earlier than expected due date next year (July 1). Speaking of the BII program at NSF – all EMBRIO members are invited to participate in the upcoming virtual BII conference October 18-19 that will involve a dozen BII Institutes. More details will be forthcoming. Steph Gardner is leading a separately funded initiative titled CUREs (course-based undergraduate research experiences) and is calling for interested EMBRIO faculty to get involved – please see the callout under “Research & Education Integration”. This is an excellent opportunity for EMBRIO to make advancements in Thrust 4 within an educational research framework. We are looking forward to seeing everyone next Monday during our Weekly Update. EMBRIO graduate students Shelly Tan and Chang Ding with Qing Deng’s lab will be presenting, and they are both featured in this edition’s Member Spotlight. Don’t forget to take a minute to vote on our new Newsletter name<https://poll-maker.com/QT52V51Y4> from Member submitted ideas…and send your news and announcements for the next newsletter to Brent (laddb(a)purdue.edu<mailto:laddb@purdue.edu>) by 9/15. David, Chris, Stephanie, Brent, and Carl QUICK LINKS EMBRIO BII NSF Annual Report 2022<https://app.box.com/s/hcu5cowhcbbhgilivwvxy28lerywu3ko> CUREs Participation Interest Survey<https://purdue.ca1.qualtrics.com/jfe/form/SV_29tas2RkBAA5e8S> Matt Thompson Thesis Defense, September 14 at 11:30, MJIS 2001, Purdue: Zoom option<https://purdue-edu.zoom.us/j/94518363803?pwd=QjQvd0x6ank0NjViODI3WW50UGRPUT…> . Propose a Zoom Breakout Group Topic for Oct. 3 Weekly Update (Email: Laddb(a)purdue.edu<mailto:Laddb@purdue.edu> ) Cast Your Vote for EMBRIO Newsletter name<https://poll-maker.com/QT52V51Y4> Weekly EMBRIO Research & Education Meeting Zoom Link (Mondays at 3 – 4pm)<https://purdue-edu.zoom.us/j/96053485465?pwd=elVnY20wcm9kaFRtVUdPcmFHaGl1UT…> INSTITUTE HIGHLIGHT Thank you to everyone involved in reporting efforts to provide the required annual progress update to our NSF BII Program Director in stewardship of our NSF Award. It’s an undertaking to pull together, and your timely responses helped the job go smoothly. The report was submitted on time with all necessary documentation and has been approved by NSF. We will look forward to, and will share, any feedback from NSF. EMBRIO Members can access the complete PDF of the Institute’s Year 1 report on Box: EMBRIO BII NSF Annual Report 2022<https://app.box.com/s/hcu5cowhcbbhgilivwvxy28lerywu3ko> Now, here’s the kicker and a heads-up for next year: We received word from our NSF Program Director, Wilson Francisco, that because of an overlapping program requirement at NSF, our Year 2 BII report will be due July 1, 2023. This means we’ll need to start much earlier on investigator progress reports. Our timeline was very compressed this year, and rather than squeeze a larger Y2 report into one month like we did this year, we anticipate a two-month process starting in early May. RESEARCH & EDUCATION INTEGRATION: CUREs PROGRAM OPPORTUNITY Want to broaden access to undergraduate research experiences in integrative biology? CUREs could be an answer! Course-based Undergraduate Research Experiences (CUREs) are a way to allow more and diverse students the opportunity to experience research by embedding real research projects into courses students might take as part of their normal coursework. CUREs can be a full-semester course in which the focus is the work on the research project, or they can be a multi-week research module embedded within a course. Stephanie Gardner has worked with instructors in one-on-one or in cohort models to train and support them as they develop and teach CUREs. Within the EMBRIO Institute engaging students in interdisciplinary research is a priority, incorporating imaging, simulation and computation, as relevant to the project. Stephanie is excited to work with interested EMBRIO graduate students, postdocs, research scientists, and faculty on CUREs. To gauge interest and help with planning, please complete this brief interest survey by September 23rd: https://purdue.ca1.qualtrics.com/jfe/form/SV_29tas2RkBAA5e8S INFORMAL CONVERSATION/COLLABORATION Zoom BREAKOUT GROUPS: Are you looking for a collaborator? Would you like to get conversation started about a specific research topic with other EMBRIO members? Beginning in October we will dedicate time during one or more Weekly Update meetings each month to allow for all participants to get-to-know each other a little better and have more opportunity to informally connect and discuss research and collaboration next steps. The person/people who propose a research topic for discussion, or a “looking for a collaborator on [fill in your topic]” will orient the breakout group by taking a few minutes to introduce the project or topic. People can choose to join a group at-will. For those not looking for a collaborator(s) or not interested in the available research topics that week will have an option to join an informal “get to know each other” chat group. We’ll also designate a “students only” breakout group for any of our trainees who want to chat with other students, however, students are encouraged to join other breakout groups as they desire. Email me (Brent, laddb(a)purdue.edu<mailto:laddb@purdue.edu>) with your breakout group topic for October 3 Weekly Update session. MEMBER SPOTLIGHT: Shelly Tan [cid:172a1fd2-3c28-430a-b32e-cdc14323953b] Shelly Tan is a graduate student in the Qing Deng Lab, Department of Biological Sciences, Purdue University. She will co-present research during our upcoming Weekly Update, September 12. What's your hometown, State, Country (and one thing you love, miss, remember or want to tell others about it)? I'm a townie! I was born in New Jersey but moved here to West Lafayette early enough that I don't remember much. I count myself pretty lucky to have grown up in such a nice place, honestly - having a university campus nearby enabled a lot of opportunities I definitely would not have gotten otherwise. What are your hobbies? Most people know this already, but my primary pastime when I'm not in the lab is digital illustration - distinct from graphic design! It's basically just painting, but on a digital canvas instead of a physical one. I like doing character illustrations most! That being said, I do a lot of other stuff when I have the time for it. I like to cook and play video games, and I'm a big stationery enthusiast as well - still on the hunt for my holy grail fountain pen, but the Pilot Vanishing Point EF is pretty close. What drew you into becoming a scientist or engineer (or both)? Ever since I was a kid, I was motivated by this really strong intrinsic curiosity (to the point of injury, sometimes - there was this incident involving the hinge side of a door and my own fingernails that I vaguely recall from my preschool years). Living so close to a college campus allowed me to get a feel from a very young age for what comprised an academic mindset, so I think I ended up growing into the role naturally. It's hard to find this level of intellectual freedom and self-driven progress in most other jobs, and I suspect that if I were doing anything else, I'd get bored very quickly. In the grand scheme of things, it's nice to finally have the training to both properly ask and rigorously answer the questions that have defined my engagement with the natural world for so long. It's been a long road, but I'm glad to be here! Tell us the main point of your research as it relates to EMBRIO: My project is part of Thrust 3B, and it focuses on the intersections between calcium signaling and actin cytoskeleton rearrangement in the zebrafish wounding model. The calcium wave and epithelial contraction seen in the embryonic zebrafish fin fold immediately post-injury are conserved between multiple phyla, but their respective roles in the overall wound healing process (especially in this system) are poorly understood. Using chemical and genetic tools, we aim to characterize the mechanisms underlying these coordinated whole-tissue signals in vivo, as well as to interrogate how their particular intersections support the complex morphology that typically comprises the vertebrate wound response. You find yourself alone on an elevator with the president of your university – who knows very little about your field: They ask you to tell them about your research (15 seconds - go!): I cut up baby zebrafish and then take pictures! Haha, maybe that's an oversimplification, but it does teach us a lot about how cells "talk" to each other when the tissue they're part of is injured, and how they rearrange in response to damage. Using special dyes and microscopy, we can visualize the chemical language they use to communicate - a language that's evolutionarily conserved from fruit flies all the way to human cells. What's on the horizon for you (research, career, personal, whatever you want to share)? If graduating in the age of COVID has taught me one thing, it's to not make plans too far in advance. Given we're currently experiencing "once in a generation" events every other week, let's just say I'm keeping my options open and trying to get involved in as much cool stuff as I can! What’s your various URL/social media handles that others can follow (prof. website, twitter, LinkedIn, blog, etc)? All my social media is under a pen name for privacy reasons, so unfortunately I don't have any links to share. Keep an eye on this space, though - that might change in the near future! MEMBER SPOTLIGHT: Chang Ding [cid:b12ad416-9f16-4d6b-af54-be5cd39b84ac] Chang Ding is a graduate student in the Qing Deng Lab, Department of Biological Sciences, Purdue University. She will co-present research during our upcoming Weekly Update, September 12. What's your hometown, State, Country (and one thing you love, miss, remember or want to tell others about it)? I am from Harbin, a city in the northeastern part of China. It is also called ice city for its freezing temperature in the winter. It could even get to -35 degrees at midnight, thus I could definitely tolerate Purdue’s winter. What are your hobbies? I am very interested in photography but not talented at taking pictures, LOL. Even though I tried hard to read books that tell about how changing angles could make pictures look a lot different than it used to, I seldom get one that I like when I have my camera with me. What drew you into becoming a scientist or engineer (or both)? I guess it is out of curiosity, and I think most scientists are curious about the questions they ask. Or it will be hard to keep me working in the lab when I am not curious about what will happen after handling fish, LOL. Tell us the main point of your research as it relates to EMBRIO: My project is also in Thrust 3B and I am working on revealing the role that reactive oxygen species (ROS) play in the zebrafish tailfin wound healing process. Our preliminary data support that the ROS promotes tissue relaxation after the initial wound contractions. The goal is to determine the mechanism of how ROS provides negative regulation of wound contraction, and model the calcium-ROS-actin regulation in the tissue mathematically. You find yourself alone on an elevator with the president of your university – who knows very little about your field: They ask you to tell them about your research (15 seconds - go!): In order to know more about the mechanism that I am studying, we usually either treat fish with some drug or inject some other drugs into their embryos. After comparing their responses with fish without any treatment, we will be able to determine whether targeted components are affecting the signaling pathway. What's on the horizon for you (research, career, personal, whatever you want to share)? I am always a person that plans ahead and gets prepared for those things even though sometimes it is too early to do so. What’s your various URL/social media handles that others can follow (prof. website, twitter, LinkedIn, blog, etc)? I don’t have any of those social media : ), and I never post myself on social media. LOL Maybe I will get one in the future. UPCOMING DEADLINES, IMPORTANT DATES, & INFO Weekly Research & Education Zoom Meetings Fall Semester, Monday’s 3 – 4 pm. Zoom link: https://purdue-edu.zoom.us/j/96053485465?pwd=elVnY20wcm9kaFRtVUdPcmFHaGl1UT… * September 12, Presenters: Shelly Tan & Chang Ding (Qing Deng Lab), GuangJun Zhang Lab. * September 19, Presenters: Juana Mendenhall Lab, Aritra Chatterjee (Deva Chan Lab) * September 26, Presenters: Jeremy Zartman Lab, Sharon Minsuk (James Glazier Lab) September 14: EMBRIO THESIS DEFENSE: Ph.D. Candidate, Matthew Thompson, with the Umulis Lab, will defend his dissertation September 14 at 11:30 in MJIS 2001 on the Purdue Campus. Everyone can join via Zoom option<https://purdue-edu.zoom.us/j/94518363803?pwd=QjQvd0x6ank0NjViODI3WW50UGRPUT…> . If you (or a mentee) have a thesis defense coming up, let us know! * Advancing Interdisciplinary Undergraduate STEM Education for Increased Workforce Preparation Virtual Workshop, September 21, 2022 | 2:00 - 3:30 PM ET Workshop Information and Registration<https://www.aaas-iuse.org/event/advancing-interdisciplinary-undergraduate-s…> September 23, 2022. EMBRIO Related Talk. Chris Staiger will present an in-person talk titled “Cooperative actin filament nucleation in the homeostatic cortical array of plant cells” at the Chicago Cytoskeleton meeting on Friday, September 23. For more information about the meeting visit the CC website: https://chicagocytoskeleton.net/ September 23, 2022. Response Deadline for Interest in CUREs Program To gauge interest and help with planning, please complete this brief interest survey for participation in Course-based Undergraduate Research Experiences (CUREs): https://purdue.ca1.qualtrics.com/jfe/form/SV_29tas2RkBAA5e8S October 12-15, 2022. The Biomedical Engineering Society (BMES) 2022 Annual Meeting<https://s7.goeshow.com/bes/annual/2022/> will be held in San Antonio, Texas. Registration is open. October 18-19, 2022. Our NSF Biology Integration Institutes Annual Conference will be held virtually and run by NSF BII Program Officers. ALL EMBRIO members are encouraged to participate, as you are able. Registration link, schedule, and topic session details are forthcoming. Each day is forecast to run from 10am – 5pm EST. At this early-stage discussions are focused on sessions that are most useful for developing successful institutes, team science and overcoming integration challenges, NSF expectations, student perspectives on interdisciplinary mentoring, methods and lessons learned on data sharing and management, and modeling approaches in common with most BII’s. Stay tuned for more information. Nov. 9 – Nov. 12: The Annual Biomedical Research Conference for Minoritized Scientists (ABRCMS)<https://abrcms.org/> is a go-to conference for underrepresented groups in STEM fields. Jan. 2 – 6, 2023: The BMES Cellular and Molecular Bioengineering Special Interest Group is seeking abstracts for the BMES Conference (CMBE)<https://www.bmes.org/2023-cmbe-conference> in Indian Wells, CA. DEADLINE for submissions is September 14. Hot Off the Press: New EMBRIO Papers Matthew J. Thompson, Vidhya Munnamalai, David M. Umulis (8/30/2022) Early precision of radial patterning of the mouse cochlea is achieved by a linear BMP signaling gradient and is further refined by SOX2. bioRxiv 2022.08.30.505910; doi: https://doi.org/10.1101/2022.08.30.505910 Let us know about new papers you want to highlight for the EMBRIO community! REMINDER: EMBRIO Acknowledgement for Scholarly Papers. For EMBRIO related research publications, NSF requires acknowledgement of EMBRIO NSF funding for our Institute to claim the work in our reporting back to NSF. Please include the following acknowledgement in your journal and conference papers and posters: “This work is based upon efforts supported by EMBRIO Institute, contract #2120200, a National Science Foundation (NSF) Biology Integration Institute.” Awards National Science Foundation Faculty Early Career Development (CAREER) Awards: Congrats to Elsje Pienaar<https://engineering.purdue.edu/BME/Academics/Graduate/CurrentResearchOpport…>, Assistant Professor of Biomedical Engineering (College of Engineering), for Complexity From Simplicity: Multi-scale Computational Deciphering of the Viral Life Cycle<https://nsf.gov/awardsearch/showAward?AWD_ID=2143866&HistoricalAwards=false>. The award, granted as part of the American Rescue Plan Act of 2021, will use a combination of experimental data and computer simulations to understand and predict the complex interactions that drive Ebola virus infection. Such an understanding will allow the identification of any weak points in this protein network that can be targeted with new drugs. New Lab Members? Did you recently have new students or staff members join your EMBRIO projects? We want to add them to the listserv, Box account, demographics survey, and Personnel List for ensuring their inclusion in communications and participation. If they are not already on our Personnel spreadsheet ( https://app.box.com/s/frd9275xc069gmgtbe3y1osoz1j7ssk7 ), or they have graduated, let Brent know their names and email contacts (laddb(a)purdue.edu<mailto:laddb@purdue.edu> ) Submit your items for the next newsletter by Sept. 15 to Brent (laddb(a)purdue.edu<mailto:laddb@purdue.edu>) Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering Purdue University laddb(a)purdue.edu <https://www.purdue.edu/research/embrio/>

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EMBRIO announcements
by Brent T Ladd 02 Sep '22

02 Sep '22

Dear EMBRIO Community, A few announcements: Our Weekly Update is canceled on Monday, September 5th in observance of the Labor Day Holiday. We will be back September 12 with presentations by Qing Deng’s Lab and GuangJun Zhang’s Lab. Thank you to everyone involved in reporting efforts to provide an annual progress update to our NSF program manager in stewardship of our NSF funding. Your timely responses made the job go smoothly. The report was submitted on time with all necessary documentation. We will look forward to, and share, any feedback from NSF. EMBRIO Members can access the complete PDF of the Institute’s Year 1 report on Box: EMBRIO BII NSF Annual Report 2022<https://app.box.com/s/hcu5cowhcbbhgilivwvxy28lerywu3ko> October 18-19, 2022. Our NSF Biology Integration Institutes Annual Virtual Conference will be held online and run by NSF BII Program Officers. ALL EMBRIO members are encouraged to participate, as you are able. Registration link, schedule, and topic session details are forthcoming from NSF. Each day is forecast to run from 10am – 5pm EST. At this early-stage, planning discussions are focused on sessions that are most useful for developing successful institutes, team science and overcoming integration challenges, NSF expectations, student perspectives on interdisciplinary mentoring, methods and lessons learned on data sharing and management, and modeling approaches in common with most BII’s. Stay tuned for more information. Send your news items and announcements today to me (laddb(a)purdue.edu<mailto:laddb@purdue.edu>) for inclusion in the next edition of the EMBRIO newsletter. Wishing everyone a safe and enjoyable Labor Day Holiday, Brent Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering Purdue University laddb(a)purdue.edu <https://www.purdue.edu/research/embrio/>

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NSF email request for demographics
by Brent T Ladd 31 Aug '22

31 Aug '22

Hello EMBRIO Members, I want to alert you that upon submission of our NSF annual report today an automatic email is sent to all personnel involved in the project. The email from NSF asks for you to visit this site: https://www.fastlane.nsf.gov/cgi-bin/people within the email NSF will provide you with a temporary PIN, and you must enter our NSF project # 2120200. The email has further directions for entering your demographic information. This is a real email from NSF - not spam! Thanks, and a huge thank you to all EMBRIO Investigators for your timely reports and responses during this first year reporting process!! Brent Brent T. Ladd, MS Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Director of Education & Diversity, Center for Science of Information<http://www.soihub.org/> Purdue University laddb(a)purdue.edu <https://www.purdue.edu/research/embrio/>

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EMBRIO Weekly Update today at 3pm
by Brent T Ladd 29 Aug '22

29 Aug '22

Dear EMBRIO Members, We kick off Fall semester Weekly Updates today at 3 pm via Zoom (link and call-in details below.) Stephanie Gardner will present on the Institute's Core Values for continued discussion and input, and Matt Thompson will present his research with the Umulis Lab. Brent Ladd is inviting you to a scheduled Zoom meeting. Join Zoom Meeting https://purdue-edu.zoom.us/j/96053485465?pwd=elVnY20wcm9kaFRtVUdPcmFHaGl1UT… Meeting ID: 960 5348 5465 Passcode: 680714 One tap mobile +16469313860,,96053485465#,,,,*680714# US +13017158592,,96053485465#,,,,*680714# US (Washington DC) Dial by your location +1 646 931 3860 US +1 301 715 8592 US (Washington DC) +1 312 626 6799 US (Chicago) +1 646 558 8656 US (New York) +1 669 900 6833 US (San Jose) +1 253 215 8782 US (Tacoma) +1 346 248 7799 US (Houston) +1 386 347 5053 US +1 564 217 2000 US +1 669 444 9171 US Meeting ID: 960 5348 5465 Passcode: 680714 Find your local number: https://purdue-edu.zoom.us/u/acg94V2zgH [https://us01st-cf.zoom.us/static/6.2.8216/image/thumb.png]<https://purdue-edu.zoom.us/u/acg94V2zgH> Video Conferencing, Web Conferencing, Webinars, Screen Sharing<https://purdue-edu.zoom.us/u/acg94V2zgH> Zoom is the leader in modern enterprise video communications, with an easy, reliable cloud platform for video and audio conferencing, chat, and webinars across mobile, desktop, and room systems. Zoom Rooms is the original software-based conference room solution used around the world in board, conference, huddle, and training rooms, as well as executive offices and classrooms. Founded in 2011, Zoom helps businesses and organizations bring their teams together in a frictionless environment to get more done. Zoom is a publicly traded company headquartered in San Jose, CA. purdue-edu.zoom.us Brent T. Ladd, MS Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Director of Education & Diversity, Center for Science of Information<http://www.soihub.org/> Purdue University laddb(a)purdue.edu <https://www.purdue.edu/research/embrio/>

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EMBRIO Newsletter August 25
by Brent T Ladd 25 Aug '22

25 Aug '22

[cid:aa03d580-887f-491e-9df1-3475230037ac] “EMBRIO NEWS” : submit your Newsletter name ideas (laddb(a)purdue.edu<mailto:laddb@purdue.edu>). We’ll vote on it in the next edition. August 25, 2022 DIRECTORS NOTE With this edition of the newsletter, we welcome you all back to Fall semester, and hope you have each had a positive finish to your summer season. The Institute is looking forward to building on momentum from our Annual Retreat as we resume Weekly Research Updates next Monday featuring Matt Thompson’s doctoral research in the Umulis Lab. Assistant Director, Stephanie Gardner will be giving an overview of the Institute’s Core Values along with feedback submitted from the membership (visit the Core Values slide link below to contribute). Diversity and inclusive belonging are an important thread woven throughout our Core Values. Collectively, we will continue to strengthen these in our growth as an Institute. We begin this newsletter with a statement drawn directly from our Core Values in a Commitment to Diversity and Inclusive Belonging. Your continued reflections, input, feedback, and ideas of how we can continue to improve in these areas is always welcomed. In closing, we are particularly proud of the research, learning, and progress made by the twenty undergraduate scholars who conducted exciting projects under the mentorship of EMBRIO faculty. We have high hopes for their continued involvement in the Institute. These students and their mentors are featured in the Institute Highlight. David, Chris, Stephanie, Brent, and Carl QUICK LINKS Weekly EMBRIO Research & Education Meeting Zoom Link (Mondays at 3 – 4pm)<https://purdue-edu.zoom.us/j/96053485465?pwd=elVnY20wcm9kaFRtVUdPcmFHaGl1UT…> EMBRIO Core Values Feedback Google Slides<https://tinyurl.com/5h49w85n> New EMBRIO Member Demographics Survey<https://purdue.ca1.qualtrics.com/jfe/form/SV_5yIrHqxH1hHLl8a> COMMITMENT TO DIVERSITY & INCLUSIVE BELONGING The EMBRIO Institute is committed to prioritizing diversity, equity, inclusion, social justice, and accessibility for ALL of its members. To support these priorities, we must ALL continuously reflect on how each aspect of EMBRIO’s operation and agenda is designed and implemented so that it ensures ALL members are able to access and participate in Institute activities. By embracing the benefits of diversity together, we will drive scientific innovation and growth. The diversity of experiences and resources that EMBRIO members possess enriches our work together. To this end, we empower EMBRIO members to take the initiative within their own projects, education, and outreach activities to develop new leaders, spark innovation, and engender a sense of mutual responsibility and ownership of the Institute. As a result of honoring and supporting our collective diversity, each Institute member will be transformed and contribute to the transformation of others as a result of this collaborative endeavor. INSTITUTE HIGHLIGHT EMBRIO Undergraduate Research Experiences Summer Program Our first summer as an institute was very productive in mentoring undergraduate students in research related to EMBRIO. Institute-wide, 20 students from 8 institutions engaged in mentored undergraduate research experiences, with 11 EMBRIO faculty serving as mentors. The Institute organized a ten-week Undergraduate Research Experience on the Purdue campus during the period of May 23 – August 1, 2022. Fourteen students participated at Purdue representing six institutions (Purdue, Morehouse, UPRM, LSU, Miami, N.C. State). In addition to the EMBRIO summer program at Purdue, The Zartman Lab at Notre Dame organized an URE mentoring one UPRM student and one high school student, the Mendenhall Lab organized an academic and summer URE at Morehouse College mentoring two Morehouse students, and the Cabrera-Rios Lab at University of Puerto Rico – Mayaguez mentored two UPRM students. The table below provides a listing of the undergraduate students, faculty mentors, and their project titles. Projects of participating students in EMBRIO Undergraduate Research Experience, Summer 2022. Name Home University Faculty Mentor Project Title Christiana Whittey Purdue C. Staiger Establishing a new pathosystem (Colletotrichum–Onion) for penetration-mediated resistance to fungal attack of plant cells. Morgan Murff Purdue C. Staiger Exploration into pre-penetration MAMPs and their effect on actin cytoskeleton rearrangement. Kenneth Tre’ Jahn Jones North Carolina A&T T. Kinzer-Ursem Investigation of the Interactions of Neuronal Proteins in an Animal Model of Alzheimer’s Disease Sami Hallett Purdue J. Evans Observing microfilament dynamics in live mouse oocytes with the actin probe SiR-Actin Kioni Bush Purdue Q. Deng Integration of Actin and Calcium in Embryonic Zebrafish Wounding Model Ambrose Haskin Morehouse D. Chan Measuring the Effect of Cerium Oxide Nanoparticles (CeO NPs) in 3D Printed Hydrogels Chiana Barski UPR-Mayaguez C. Staiger ARP 2/3 Complex Mediated Actin Filament Response in Presence of MAMP Treatment Adriana Santos-Bague UPR-Mayaguez Q. Deng Act1 Knockout effects on Interleukin 17 mediated neutrophil recruitment Nathan French Purdue D. Umulis Investigation and Quantification of the pSmad Profile in Early Embryonic Development of Bambia Mutant Zebrafish Jaylin Trice Louisiana State J. Linnes Blood Sample Preparation for HIV Diagnostics in a Smartphone-based Microfluidic Device Ana Claure Miami J. Linnes Optimizing a 37 degree Celsius isothermal nucleic acid amplification of human papilloma virus strain 16 (HPV 16) to detect individuals at high risk of cervical cancer Eanna DeGuzman Purdue S. Gardner Qualitative research methodologies to characterize EMBRIO activities, scientific explanations, and interactions. Keni Jiang Purdue Q. Deng ROS mediate relaxation and regrowth of zebrafish fin after amputation. (Tim) Ting Hsuan Ku Purdue Q. Deng Improving Under Agarose Gel Assay by 3D Printing for Investigating Neutrophil Migration Jose Martinez Alvarad UPR-Mayaguez J. Zartman Identification of new organ size regulators: Positive feedback between the G-protein Coupled Receptor Methuselah like-8 and Galphaq. Anne Malott High school student J. Zartman Functional Analysis of Piezo in Rasv12 Mediated Cancer Progression. Jonathan Banks Morehouse J. Mendenhall Evaluating the Mechanical Properties of 3d printed Hydrogels using varying water content levels. Jordan Turner Morehouse J. Mendenhall Development of Supramolecular Bioinks using Gene-Activated 3D Laden Hydrogels for Therapeutic Cartilage Tissue Regeneration. Wilfrido Ramos UPR-Mayaguez M. Cabrera-Rios The use of Jupyter Notebooks and Github in research. Richardson Calderon UPR-Mayaguez M. Cabrera-Rios The use of Jupyter Notebooks and Github in research. CELEBRATING… EMBRIO’s First Baby!! [cid:affa3fac-d45e-463f-8208-85075cc542e4] Many congratulations to Deva Chan (EMBRIO Faculty, and Assistant Professor of Biomedical Engineering at Purdue) and her family! Join us in welcoming BRANDON, EMBRIO’s first baby. He arrived August 1 weighing in at 8 lbs. 8 oz and 22” long!! MEMBER SPOTLIGHT: Matthew Thompson [cid:d2db31e5-384a-47be-97bf-9fd1a61eee2c] Matt is a Ph.D. Candidate conducting research in the Umulis Lab in the Weldon School of Biomedical Engineering at Purdue University. He will be presenting at Monday’s EMBRIO Weekly Research Update (Aug. 29) and defending his thesis September 14 at 11:30 in MJIS 200. Everyone can join his thesis defense talk via a Zoom option<https://purdue-edu.zoom.us/j/94518363803?pwd=QjQvd0x6ank0NjViODI3WW50UGRPUT…>. What's your hometown, State (and one thing you love, miss, remember or want to tell others about it)? Fort Wayne, IN / I miss having family in town and the view overlooking a hill and field behind our house. What drew you into becoming a scientist or engineer (or both)? Originally drawn to engineering because Iron Man had recently hit theaters (only half joking), I found my way from a BS in Mechanical Engineering to an MS in Biomedical Engineering after taking a Principles of Tissue Engineering course in my early graduate studies and realizing I hadn’t given biology a fair review from my experience with it in high school. Working with CRISPR-Cas9, I discovered that proteins really are the ultimate nanomachines. I then joined David’s lab wanting to merge my still-new interests in biology with engineering and modeling tools I knew the lab excelled at and further hone my research abilities. What are your hobbies? Saturday morning bike rides with my family, YouTube fitness videos using a 5 and 2 year old as resistance, playing piano and listening to music when there’s space in the day. You find yourself alone on an elevator with the President of your university: s/he asks you to tell them about your research (15 seconds - go!): “You know how you can hear the words I’m saying right now? The pattern of the cells in your inner ear that make that possible is created in large part by a complicated network of interacting signaling proteins during development. I’m working on figuring out how these signals communicate patterning or positional information to the cells to let them know where they are in the pattern and what mechanisms are in place that help shape the signals to be that way.” What's on the horizon for you (research, career, personal, whatever you want to share)?: In essence, I plan to support the way interdisciplinary or cross-functional teams work together to accomplish big things in science and engineering. The opportunity to develop “sociotechnical” approaches that merge the advantages and needs of our human-ness with those of computers and lab equipment is large, and I look forward to contributing my skills and interests to that broad goal in academic-adjacent or industry roles. That is to say, something that merges ideas from data engineering, project management, and product management applied to scientific research. What's your various URL/social media handles (prof. website, twitter, LinkedIn, blog, etc) Matt’s LinkedIn: https://www.linkedin.com/in/thompson-m-j/ UPCOMING DEADLINES, IMPORTANT DATES, & INFO Investigator Annual Reporting Deadlines: We are on a tight timeline to report our Yr. 1 progress to NSF. The schedule for reporting: * Fri August 26 Final draft available to Investigators for comment * Mon, August 29 Investigator comments on Final draft due to Manager(s) * Wed. Aug. 31 Completed Annual Report due to NSF Weekly Research & Education Zoom Meetings Fall Semester, Monday’s 3 – 4 pm. Note the NEW Zoom link: https://purdue-edu.zoom.us/j/96053485465?pwd=elVnY20wcm9kaFRtVUdPcmFHaGl1UT… * August 29th: Matthew Thompson (Umulis Lab) Research Talk Stephanie Gardner will provide an overview and feedback received from members on EMBRIO’s nine Core Values. * September 5, no meeting due to Labor Day holiday. * September 12, Presenters: Shelly Tan & Chang Ding (Deng Lab), GuangJun Zhang Lab. September 14: EMBRIO THESIS DEFENSE: Ph.D. student, Matthew Thompson with the Umulis Lab will defend his dissertation September 14 at 11:30 in MJIS 2001 on the Purdue Campus. Everyone can join via Zoom option<https://purdue-edu.zoom.us/j/94518363803?pwd=QjQvd0x6ank0NjViODI3WW50UGRPUT…> . New EMBRIO Listserv: To aid in managing Institute-wide communications, we’ve started an official listserv: embrio-list(a)ecn.purdue.edu<mailto:embrio-list@ecn.purdue.edu> . We’ll use it to disseminate information like this newsletter and other announcements. New Lab Members? Did you recently have new students or staff members join your EMBRIO projects? We want to add them to the listserv, Box account, demographics survey, and Personnel List for ensuring their inclusion in communications and participation. If they are not already on our Personnel spreadsheet ( https://app.box.com/s/frd9275xc069gmgtbe3y1osoz1j7ssk7 ) let Brent know their names and email contacts (laddb(a)purdue.edu<mailto:laddb@purdue.edu> ) Member Demographics Survey: For new members that have joined EMBRIO since March, please complete the online survey (https://purdue.ca1.qualtrics.com/jfe/form/SV_5yIrHqxH1hHLl8a ). This demographics information, although voluntary, greatly aids the Institute in tracking our progress on diversity initiatives. Faculty, please forward the demographics survey to any new trainees or interns that have recently joined the Institute. Core Values Feedback. In addition to EMBRIO’s Vision and Mission, our Strategic Plan includes nine Core Values that provide a guiding foundation for the culture and communities of practice we strive to build. The strategic plan is a living document, owned by all members of the Institute. Stephanie Gardner presented our shared Core Values statements at our recent annual retreat and invited all members to provide feedback and input. We invite you ALL to provide feedback and input based on your experience in the institute thus far. This will not be the last time we revisit these values to reflect and improve the institute, but we request that you offer your input for this round by August 26. You can do so anonymously within the Google Slides set (slides 6-15): https://tinyurl.com/5h49w85n October 12-15, 2022. The Biomedical Engineering Society (BMES) 2022 Annual Meeting<https://s7.goeshow.com/bes/annual/2022/> will be held in San Antonio, Texas. Registration is now open! You can save a lot of money by registering early – early bird registration ends September 6. Nov. 9 – Nov. 12: The Annual Biomedical Research Conference for Minoritized Scientists (ABRCMS)<https://abrcms.org/> is a go-to conference for underrepresented groups in STEM fields. Jan. 2 – 6, 2023: The BMES Cellular and Molecular Bioengineering Special Interest Group is seeking abstracts for the BMES Conference (CMBE)<https://www.bmes.org/2023-cmbe-conference> in Indian Wells, CA. DEADLINE for submissions is September 14. **Submit your items for the next newsletter by Sept. 1 to Brent (laddb(a)purdue.edu<mailto:laddb@purdue.edu> )** <https://www.purdue.edu/research/embrio/>

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EMBRIO Newsletter submissions - by Friday noon
by Brent T Ladd 19 Aug '22

19 Aug '22

Submit your items for inclusion in the EMBRIO Newsletter by this Friday, noon to Brent (laddb(a)purdue.edu<mailto:laddb@purdue.edu> with subject line: EMBRIO news items). Examples include relevant training and professional development workshops, seminars, conferences, awards, publications, trainee dissertation titles and defense dates, recruitment/openings, tools and resources, and other pertinent news or announcements that our EMBRIO community should know about! Thanks, Brent Brent T. Ladd, MS Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Director of Education & Diversity, Center for Science of Information<http://www.soihub.org/> Purdue University laddb(a)purdue.edu <https://www.purdue.edu/research/embrio/>

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