October 2025 - Embrio-list

Weekly Update
by Brent Thomas Ladd 29 Oct '25

29 Oct '25

[cid:0c45820d-b7a7-49f6-957a-02a9a3631cc8] Dear EMBRIO Members, This coming Monday 3-4pm ET will feature the Kim lab with Ph.D. student Jeffery Coulter presenting on his collaborations with the Evans Lab and Kinzer-Ursem Lab in Thrust 1 with modeling Ca2+ and actin in dendritic spines and oocytes. Upcoming All-Hands Labs (3PM ET): Date Lead Speaker(s) Topic November 3 Jeffery Coulter (Kim Lab) – collaborations with Evans Lab and Kinzer-Ursem Lab Modeling Ca2+ and Actin in Dendritic Spines and Oocytes November 17 Alex Nguyen (Chan Lab) – collaborations with Evans Lab, Zartman Lab, Deng Lab AFM and Imaging ________________________________ LSFM Workshop Happening This Week EMBRIO teamed up with the Purdue Imaging Facility and Bruker to offer a three-day light-sheet fluorescence microscopy (LSFM) workshop on the Purdue campus this week, with hands-on demonstrations continuing today and tomorrow using the Bruker MuVi SPIM system. Participants are learning fundamental principles, exploring the applications in biological research, while practicing imaging workflows with expert guidance. Thank you to Dr. Weiwei Zhang, and Ph.D. student Nissa Larson for presentations yesterday highlighting how they have each used LSFM in their EMBRIO related research. ________________________________ Awards: 👏 Congratulations to Soumi Mukherjee (Gardner Lab) on her award-winning poster presentation at the recent 150th Anniversary of the Purdue Biological Sciences symposium! Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering, Purdue University Office: Hall for Discovery Learning and Research, Ste. 203 207 S. Martin Jischke Drive West Lafayette, IN 47907 laddb(a)purdue.edu

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End of Week Announcements
by Brent Thomas Ladd 24 Oct '25

24 Oct '25

EMBRIOphytes, 🧬 New Publications Alert! * EMBRIO Members from the Zartman Lab have a newly published paper in Cell Communication and Signaling (first co-authors: Maria F. Unger, Vijay Velagala, Dharsan K. Soundarrajan) "Gαq controls organ size and developmental timing in Drosophila" Summarized findings and link to the full paper is below. 👏 Congrats to the team: Maria F. Unger, Vijay Velagala, Dharsan K. Soundarrajan, David Gazzo, Nilay Kumar, Marycruz Flores Flores, Jinwen Liu, Jun Li & Jeremiah J. Zartman. * Also, you heard it here first: The Calcium Signaling Journal Club's sustained collaborations have produced a newly accepted paper for publication in APL Bioengineering: "Rules of Life at the Interface of Calcium Signaling and Mechanobiology". This significant cross-thrust effort proposes a unifying framework where calcium signaling governs biological organization across scales. 👏 Congratulations to the full team! Once it is publicly available, we'll highlight the paper and the framework introducing three proposed Rules of Life. In the meantime, you can access the preprint version<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.prepr…>. * In case you missed our previous publication highlight, a recent paper elucidating ROS and wound healing led by the Deng Lab collaborating with the Umulis, Chan, and Buganza labs was published in Biophysical Journal: “Reactive Oxygen Species Counteract Zebrafish Wound Contraction and Promote Wound Healing” by C. Ding, L. Li, Y. Wang, H.A.A. Nguyen, D.D. Chan, D.M. Umulis, A.T. Buganza, and Q. Deng. Read the full article here: https://doi.org/10.1016/j.bpj.2025.09.027<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2…> * A manuscript has been accepted for publication in Journal of Cell Biology resulting from collaborations between the Deng lab and the EMBRIO members of Staiger, Jayant, and Zhang Labs: "Inwardly rectifying potassium channels promote directional sensing during neutrophil chemotaxis". We'll have a highlight out once the paper is publicly available. Publications Highlight: 📄 Gαq controls organ size and developmental timing in Drosophila Unger, M.F., Velagala, V., Soundarrajan, D.K. et al. Gαq controls organ size and developmental timing in Drosophila. Cell Commun Signal 23, 457 (2025). https://doi.org/10.1186/s12964-025-02449-9<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2…> Using the fruit fly Drosophila melanogaster as a model, the team uncovered how the G protein alpha subunit Gαq regulates epithelial growth and developmental timing. Overexpression of Gαq in wing discs led to reduced wing size and systemic developmental delay—mediated by Ca²⁺-dependent Dilp8 signaling. 🧠 Key findings: •Gαq overexpression decreases cell proliferation and apoptosis •Activates JAK/STAT and stress-response pathways •Triggers secretion of Dilp8, a hormone coordinating growth and timing •Links GPCR signaling to systemic developmental coordination 💡 Why it matters: This work sheds light on how Gαq signaling influences organ size and timing, with implications for understanding diseases like Sturge-Weber syndrome and uveal melanoma, where Gαq mutations are prevalent. 👏 Congrats to the team: Maria F. Unger, Vijay Velagala, Dharsan K. Soundarrajan, David Gazzo, Nilay Kumar, Marycruz Flores Flores, Jinwen Liu, Jun Li & Jeremiah J. Zartman. ________________________________ Upcoming All-Hands Labs (3PM ET): Date Lead Speaker(s) Topic November 3 Jeffery Coulter (Kim Lab) – collaborations with Evans Lab and Kinzer-Ursem Lab Modeling Ca2+ and Actin in Dendritic Spines and Oocytes November 17 Alex Nguyen (Chan Lab) – collaborations with Evans Lab, Zartman Lab, Deng Lab AFM and Imaging Thanks again to Linlin Li (Sr. Research Scientist, Umulis Lab) and Shenyu Lu (Ph.D. student in Joy Wang Lab) for presenting their collaborative findings and future plans last Monday: "AI-POWERED ACCELERATION AND PARAMETER TUNING FOR COMPUTATIONAL MODELING” . The video recording, transcript, and summary notes are available on our shared Box account: https://app.box.com/s/ftdi5zwn7040mhigbn8e5qs5ha8ecgm5<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fapp.box.c…> ________________________________ Awards: 👏 Congratulations to David Gazzo (Zartman Lab) who won a Graduate Student Travel Award from BMES to participate in the Cellular and Molecular Bioengineering (CMBE) conference this coming January. ________________________________ Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering, Purdue University Office: Hall for Discovery Learning and Research, Ste. 203 207 S. Martin Jischke Drive West Lafayette, IN 47907 laddb(a)purdue.edu

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Announcements: Today's All-Hands Topic and Registration for the LSFM Workshop
by Brent Thomas Ladd 20 Oct '25

20 Oct '25

Dear EMBRIO, Plan to join our all-hands lab meeting today at 3pm on AI-POWERED ACCELERATION AND PARAMETER TUNING FOR COMPUTATIONAL MODELING (details and zoom link below). Discover the power of Light-Sheet Fluorescence Microscopy for fast, high-res 3D imaging! Register (free) for the LSFM Workshop<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca…> (taking place 10/28-29 at Purdue, flyer attached with QR codes and details; basic info below). All-Hands Lab Meeting Today at 3pm ET "AI-POWERED ACCELERATION AND PARAMETER TUNING FOR COMPUTATIONAL MODELING” in a collaboration between the Umulis Lab (Biomedical Engineering) and Wang Lab (Electrical and Computer Engineering). Linlin Li (Sr. Research Scientist, Umulis Lab) will start with the backgrounding concepts and previous achievements, and Shenyu Lu (Ph.D. student in Joy Wang Lab) will present recent progress and findings. Zoom link: https://purdue-edu.zoom.us/j/92061591849?pwd=wclgpzLpzWKsZ9M2XYwM7Kbumaabr3…<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-ed…> Upcoming All-Hands Labs (3PM ET): Date Lead Speaker(s) Topic November 3 Jeffery Coulter (Kim Lab) – collaborations with Evans Lab and Kinzer-Ursem Lab Modeling Ca2+ and Actin in Dendritic Spines and Oocytes November 17 Alex Nguyen (Chan Lab) – collaborations with Evans Lab, Zartman Lab, Deng Lab AFM and Imaging Light-Sheet Fluorescence Microscopy Workshop: Advanced 3D Imaging for Biological Research Led by Purdue Bindley Bioscience Center (with Dr. Weiwei Zhang), together with Bruker and EMBRIO Institute. This is an excellent opportunity for EMBRIO members to have focused instruction and gain skills in this imaging modality. There are hands-on opportunities to bring your own samples. The workshop will be held October 28-29, 2025, on the Purdue campus, with options for the first half of day one via Zoom. For EMBRIO members at our partner locations interested in attending this training in person, please contact Brent regarding travel (laddb(a)purdue.edu) For questions about the workshop please contact Weiwei (zhan2190(a)purdue.edu ). See the attached flyer and registration page for details. Registration is free: https://purdue.ca1.qualtrics.com/jfe/form/SV_1GrEoUEHdatNBFY<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca…> Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering, Purdue University Office: Hall for Discovery Learning and Research, Ste. 203 207 S. Martin Jischke Drive West Lafayette, IN 47907 laddb(a)purdue.edu

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Announcements: LSFM Workshop Oct. 28-29, All-Hands Lab Monday Oct. 20
by Brent Thomas Ladd 17 Oct '25

17 Oct '25

[cid:3772eba9-6958-434e-abf6-a74456367cc3] Dear EMBRIOphytes, Two reminders on this beautiful autumn Friday - 1) Register for the LSFM Workshop ASAP, and 2) plan to join our all-hands lab meeting Monday afternoon led by Linlin Li (Umulis Lab) on the use of neural networks in EMBRIO research. Light-Sheet Fluorescence Microscopy Workshop: Advanced 3D Imaging for Biological Research Led by Purdue Bindley Bioscience Center (with Dr. Weiwei Zhang), together with Bruker and EMBRIO Institute. This is an excellent opportunity for EMBRIO members to have focused instruction and gain skills in this imaging modality. There are hands-on opportunities to bring your own samples. The workshop will be held October 28-29, 2025, on the Purdue campus, with options for the first half of day one via Zoom. For EMBRIO members at our partner locations interested in attending this training in person, please contact Brent regarding travel (laddb(a)purdue.edu) For questions about the workshop please contact Weiwei (zhan2190(a)purdue.edu ). See the attached flyer and registration page for details. Registration is free: https://purdue.ca1.qualtrics.com/jfe/form/SV_1GrEoUEHdatNBFY<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca…> All-Hands Lab Meeting October 20th at 3pm ET Plan to join our All-Hands Lab Meeting Monday, October 20th at 3pm ET, featuring research incorporating neural networks with presentation led by Linlin Li (Umulis Lab) and collaborators. Zoom link: https://purdue-edu.zoom.us/j/92061591849?pwd=wclgpzLpzWKsZ9M2XYwM7Kbumaabr3…<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-ed…> Thank you to Razeen Shaikh for presenting during our previous session "MIDOE: Maximally-informed Design of Experiment to infer experimentally inaccessible transcription factors dynamics". If you missed or would like to access the associated video and materials (including a summary of the session and Q&A) this is available on our shared Box account under All-Hands Meeting Recordings > 2025, direct link: https://app.box.com/s/nmvz4sy940bvse6m4tdkl94i1eujf11m<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fapp.box.c…> Upcoming All-Hands Labs (3PM ET): Date Lead Speaker(s) Topic October 20 Linlin Li (Umulis Lab) collaborations with Wang Lab and others Neural Networks November 3 Jeffery Coulter (Kim Lab) – collaborations with Evans Lab and Kinzer-Ursem Lab Modeling Ca2+ and Actin in Dendritic Spines and Oocytes November 17 Alex Nguyen (Chan Lab) – collaborations with Evans Lab, Zartman Lab, Deng Lab AFM and Imaging Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering, Purdue University Office: Hall for Discovery Learning and Research, Ste. 203 207 S. Martin Jischke Drive West Lafayette, IN 47907 laddb(a)purdue.edu

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End of Week Reminders: Register for the LSFM Workshop, Next All-Hands Oct. 20th on using Neural Networks
by Brent Thomas Ladd 10 Oct '25

10 Oct '25

Dear EMBRIO Members: A few reminders below. Those traveling for conference and/or Fall Break (Purdue's is next Monday - Tuesday) have safe and enjoyable travels. Light-Sheet Fluorescence Microscopy Workshop: Advanced 3D Imaging for Biological Research Led by Purdue Bindley Bioscience Center (with Dr. Weiwei Zhang), together with Bruker and EMBRIO Institute. This is an excellent opportunity for EMBRIO members to learn and gain skills in this imaging modality. The workshop will be held October 28-29, 2025, on the Purdue campus, with options for the first half of day one via Zoom. For EMBRIO members at our partner locations interested in attending this training, please contact Brent regarding travel (laddb(a)purdue.edu) For questions about the workshop please contact Weiwei (zhan2190(a)purdue.edu ) See the attached flyer and registration page for details. Registration is free: https://purdue.ca1.qualtrics.com/jfe/form/SV_1GrEoUEHdatNBFY<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca…> All-Hands Lab Meeting October 20th at 3pm ET Plan to join our All-Hands Lab Meeting Monday, October 20th at 3pm ET, featuring research incorporating neural networks with presentation led by Linlin Li (Umulis Lab) and collaborators. Zoom link: https://purdue-edu.zoom.us/j/92061591849?pwd=wclgpzLpzWKsZ9M2XYwM7Kbumaabr3…<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-ed…> Thank you to Razeen Shaikh for presenting during our previous session "MIDOE: Maximally-informed Design of Experiment to infer experimentally inaccessible transcription factors dynamics". If you missed or would like to access the associated video and materials (including a summary of the session and Q&A) this is available on our shared Box account under All-Hands Meeting Recordings > 2025, direct link: https://app.box.com/s/nmvz4sy940bvse6m4tdkl94i1eujf11m<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fapp.box.c…> For anyone new-ish to EMBRIO or wanting a refresher about the Institute's structure and outcomes we are striving for with research integration are encouraged to check out the materials in the Orientation folder on Box: https://app.box.com/s/om3brzae0z3o9s3c7x2fhxw6n2h1ipjt<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fapp.box.c…> Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering, Purdue University Office: Hall for Discovery Learning and Research, Ste. 203 207 S. Martin Jischke Drive West Lafayette, IN 47907 laddb(a)purdue.edu

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All-Hands Lab 3pm Today: Maximally Informed Design of Experiments, LSFM Workshop Registration, and more
by Brent Thomas Ladd 06 Oct '25

06 Oct '25

[cid:992ce85c-f893-44db-9c7e-3d3e9a845761] Dear EMBRIO Members: All-Hands Lab Meeting this afternoon at 3pm ET Plan to join our All-Hands Lab Meeting this afternoon at 3pm ET, featuring research led by Razeen Shaikh and Greg Reeves (Reeves Lab, Texas A&M) presenting "MIDOE: Maximally-informed Design of Experiment to infer experimentally inaccessible transcription factors dynamics". Abstract: The TGF-β/Smad signaling pathway regulates growth, development, and homeostasis of tissues across the animal kingdom. The pathway is activated when transforming growth factor -β (TGF-β) binds to its cognate transmembrane receptors to activate Smad2 by phosphorylation. The activated phosphor-Smad2 (PSmad2) undergoes a series of biochemical interactions with transcriptional activator Smad4 to form several oligomers, including the transcription factor (PSmad2)2/Smad4, which regulates target gene expression. Quantitative live cell imaging and mathematical modeling have been used to estimate the dynamics of (PSmad2)2/Smad4. However, due to the emergent nature of Smad2-Smad4 interactions, deconvolving the dynamics of the (PSmad2)2/Smad4 is challenging. We show that the Smad model is sloppy, has large parameter uncertainties (Ο∼1015), and the eigenvalues of the Fisher Information Matrix span over several decades. As such, well-fit parameter sets generate highly under-constrained predictions. To overcome this, we employ Profile Log-Likelihood to guide maximally informed design of experiments (MIDOE) and infer the dynamics of (PSmad2)2/Smad4. We generate these experiments computationally and validate that MIDOE can optimally constrain model predictions. We demonstrate that such careful analysis would not only improve the predictive power of models in systems biology but also reduce the time and expense of performing non-optimal experiments. Zoom link: https://purdue-edu.zoom.us/j/92061591849?pwd=wclgpzLpzWKsZ9M2XYwM7Kbumaabr3…<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-ed…> To access the introductory sessions on Biological Modeling Workflow from our first two all-hands lab meetings, see the slides and materials from Hayden Fennel and the Glazier lab via our shared box account under "All-Hands Meeting Recordings > 2025 ": https://app.box.com/s/vmoaq3w216ye0c78vxhyzmhh0j4vr8mx<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fapp.box.c…> Light-Sheet Fluorescence Microscopy Workshop: Advanced 3D Imaging for Biological Research Led by Purdue Bindley Bioscience Center (with Dr. Weiwei Zhang), together with Bruker and EMBRIO Institute. This is an excellent opportunity for EMBRIO members to learn and gain skills in this imaging modality. The workshop will be held October 28-29, 2025, on the Purdue campus, with options for the first half of day one via Zoom. For EMBRIO members at our partner locations interested in attending this training, please contact Brent regarding travel (laddb(a)purdue.edu) For questions about the workshop please contact Weiwei (zhan2190(a)purdue.edu ) See the attached flyer and registration page for details. Registration is free: https://purdue.ca1.qualtrics.com/jfe/form/SV_1GrEoUEHdatNBFY<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca…> The 150th Karling Lecture at Purdue University's Department of Biological Sciences will be given by Dr. Denise Montell on October 7, 2025 Dear EMBRIO investigators, I am hosting Dr. Denise Montell, a world-renowned cell biologist, in the fall. She will deliver our department's Karling Lecture on Oct 7, 12:30-1:30 pm in DLR 131. I have attached her Wikipedia page FYI: https://en.wikipedia.org/wiki/Denise_Montell<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fen.wikipe…> Best, Qing qingdeng(a)purdue.edu https://www.denglab.us<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.dengl…> Faculty and Research Staff: Leveraging EMBRIO in Future Proposals The beginnings of coordinating proposal efforts that dovetail with EMBRIO and member collaboration - see the editable Google spreadsheet to view potential opportunities and add new. Currently working on a strategy to best position and support these efforts among the membership. https://docs.google.com/spreadsheets/d/1MzX5ZAyn5LjiEX5uKUm1RNz8W8URxU62/ed…<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.goog…> Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering, Purdue University Office: Hall for Discovery Learning and Research, Ste. 203 207 S. Martin Jischke Drive West Lafayette, IN 47907 laddb(a)purdue.edu

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Monday All-Hands led by the Reeves Lab; New Collaborative EMBRIO Publication
by Brent Thomas Ladd 03 Oct '25

03 Oct '25

Dear EMBRIOphytes, All-Hands Lab Meeting Monday, October 6, 3pm ET Plan to join in the All-Hands Lab Meeting on Monday, October 6, 3pm ET, will feature integrative research led by Razeen Shaikh and Greg Reeves (Reeves Lab, Texas A&M) presenting "MIDOE: Maximally-informed Design of Experiment to infer experimentally inaccessible transcription factors dynamics". The collaboration involves multiple EMBRIO labs including Zartman lab and Umulis Lab. Abstract: The TGF-β/Smad signaling pathway regulates growth, development, and homeostasis of tissues across the animal kingdom. The pathway is activated when transforming growth factor -β (TGF-β) binds to its cognate transmembrane receptors to activate Smad2 by phosphorylation. The activated phosphor-Smad2 (PSmad2) undergoes a series of biochemical interactions with transcriptional activator Smad4 to form several oligomers, including the transcription factor (PSmad2)2/Smad4, which regulates target gene expression. Quantitative live cell imaging and mathematical modeling have been used to estimate the dynamics of (PSmad2)2/Smad4. However, due to the emergent nature of Smad2-Smad4 interactions, deconvolving the dynamics of the (PSmad2)2/Smad4 is challenging. We show that the Smad model is sloppy, has large parameter uncertainties (Ο∼1015), and the eigenvalues of the Fisher Information Matrix span over several decades. As such, well-fit parameter sets generate highly under-constrained predictions. To overcome this, we employ Profile Log-Likelihood to guide maximally informed design of experiments (MIDOE) and infer the dynamics of (PSmad2)2/Smad4. We generate these experiments computationally and validate that MIDOE can optimally constrain model predictions. We demonstrate that such careful analysis would not only improve the predictive power of models in systems biology but also reduce the time and expense of performing non-optimal experiments. Zoom link: https://purdue-edu.zoom.us/j/92061591849?pwd=wclgpzLpzWKsZ9M2XYwM7Kbumaabr3…<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-ed…> To access the introductory sessions on Biological Modeling Workflow from our first two all-hands lab meetings, see the slides and materials from Hayden Fennel and the Glazier lab via our shared box account under "All-Hands Meeting Recordings > 2025 ": https://app.box.com/s/vmoaq3w216ye0c78vxhyzmhh0j4vr8mx<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fapp.box.c…> New Publication on ROS and Wound Healing The latest work led by the Deng lab collaborating with the Umulis, Chan, and Buganza labs has just been published in Biophysical Journal “Reactive Oxygen Species Counteract Zebrafish Wound Contraction and Promote Wound Healing” by C. Ding, L. Li, Y. Wang, H.A.A. Nguyen, D.D. Chan, D.M. Umulis, A.T. Buganza, and Q. Deng 📄 Read the full article here: https://doi.org/10.1016/j.bpj.2025.09.027<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.org%2…> The experimental research integrating in silico linear elasticity simulation and atomic force microscopy (AFM) has uncovered a fascinating role of reactive oxygen species (ROS) in wound healing. Contrary to the traditional view of ROS in wound healing, the findings show that ROS can counteract wound contraction and actively promote tissue repair in zebrafish models. Why it matters: • Provides new insights into the mechanobiology of wound healing • Highlights potential therapeutic strategies for improving tissue regeneration • Bridges fundamental biology with translational applications Thank you to the collaborators and team, and to our funder at NSF (Award: 2120200) for supporting this important research. You can check out all of the Institute's publications and pre-prints available on our Google Scholar Page<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fscholar.g…> The 150th Karling Lecture at Purdue University's Department of Biological Sciences will be given by Dr. Denise Montell on October 7, 2025 Dear EMBRIO Investigators, I am hosting Dr. Denise Montell, a world-renowned cell biologist, in the fall. She will deliver our department's Karling Lecture on Oct 7, 12:30-1:30 pm in DLR 131. I have attached her Wikipedia page FYI: https://en.wikipedia.org/wiki/Denise_Montell<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fen.wikipe…> Best, Qing qingdeng(a)purdue.edu https://www.denglab.us<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.dengl…> Brent T. Ladd, Senior Research Program Manager, EMBRIO Institute<https://www.purdue.edu/research/embrio/> Weldon School of Biomedical Engineering, Purdue University Office: Hall for Discovery Learning and Research, Ste. 203 207 S. Martin Jischke Drive West Lafayette, IN 47907 laddb(a)purdue.edu

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