(Sent on behalf of Nan Kong) Zoom Webinar Registration: https://uchicago.zoom.us/webinar/register/WN_WhRa-t9ARYaa1fOtCVQb7w<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fuchicago.zoom.us%2Fwebinar%2Fregister%2FWN_WhRa-t9ARYaa1fOtCVQb7w&data=05%7C01%7Cbmegradstudents-list%40ecn.purdue.edu%7C5dc2df429b664b2ec25a08dbbf6b3397%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638314239373871897%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=B1gEoaowteMn4vSZVdw7wMkk437Muf5cs6sLJWQohSk%3D&reserved=0> Molecular Mechanisms of Neurodegeneration in Human Tauopathies and CTE Date: October 6, 2023 All times shown below are Chicago time (CST) All talks are 45 minutes in length and will be followed by a 15-minute Q&A session 8:30am Welcome & Introductions Christopher M. Gomez MD PhD Albina Y. Surbis Professor of Neurology University of Chicago 9:00am The Inconvenient Truth About CTE Ann McKee MD Eileen S. Trafimow Keynote Speaker William Fairfield Warren Distinguished Professor of Neurology and Pathology Boston University Chobanian & Avedisian School of Medicine Director, Alzheimer's Disease Research Center Director, BU CTE Center Director, Neuropathology VA Boston Healthcare System 10:00am Frontotemporal Dementia: From Syndrome to Molecule to Therapy Bruce L. Miller MD Eileen S. Trafimow Keynote Speaker A.W. and Mary Margaret Clausen Distinguished Professor in Neurology Director, Memory and Aging Center Founding Director, Global Brain Health Institute, UCSF 11:00am Tau's Journey from Good Guy to Bad Guy Kenneth S. Kosik MA MD Harriman Distinguished Professor of Neuroscience University of California, Santa Barbara 12:00pm Lunch Break 1:00pm Cryo-EM Structures of Tau Filaments from Human Brains Michel Goedert MD PhD Programme Leader MRC Laboratory of Molecular Biology Cambridge 2:00pm Neuroimmune Interaction Modulation by AD Risk Factors Li Gan PhD Professor and Director Helen and Robert Appel Alzheimer Disease Research Institute Weill Cornell Medicine 3:00pm Afternoon Break 3:15pm The Eileen S. Trafimow Endowment Christopher M. Gomez MD PhD 3:30pm Role of APOE and the Immune Response in Tau-Mediated Neurodegeneration David M. Holtzman MD Barbara Burton and Reuben M. Morriss III Distinguished Professor Scientific Director, Hope Center for Neurological Disorders Dept. of Neurology Washington University School of Medicine 4:30pm Trans-Network Propagation and Cellular Replication of Tau Prions Marc Diamond MD Director and Professor Center for Alzheimer's and Neurodegenerative Diseases UT Southwestern Medical Center The symposium will conclude at 5:30pm