(Sent on behalf of Nan Kong)

Zoom Webinar Registration: https://uchicago.zoom.us/webinar/register/WN_WhRa-t9ARYaa1fOtCVQb7w

Molecular Mechanisms of Neurodegeneration in Human Tauopathies and CTE

Date: October 6, 2023

All times shown below are Chicago time (CST)

All talks are 45 minutes in length and will be followed by a 15-minute Q&A session

8:30am        Welcome & Introductions

                    Christopher M. Gomez MD PhD

                        Albina Y. Surbis Professor of Neurology

                        University of Chicago

9:00am        The Inconvenient Truth About CTE

Ann McKee MD

Eileen S. Trafimow Keynote Speaker

William Fairfield Warren Distinguished Professor of Neurology and Pathology

Boston University Chobanian & Avedisian School of Medicine

Director, Alzheimer's Disease Research Center

Director, BU CTE Center

Director, Neuropathology VA Boston Healthcare System

10:00am      Frontotemporal Dementia: From Syndrome to Molecule to Therapy

Bruce L. Miller MD

Eileen S. Trafimow Keynote Speaker

A.W. and Mary Margaret Clausen Distinguished Professor in Neurology

Director, Memory and Aging Center

Founding Director, Global Brain Health Institute, UCSF

11:00am      Tau's Journey from Good Guy to Bad Guy

Kenneth S. Kosik MA MD

Harriman Distinguished Professor of Neuroscience

University of California, Santa Barbara

12:00pm          Lunch Break

1:00pm       Cryo-EM Structures of Tau Filaments from Human Brains

Michel Goedert MD PhD

Programme Leader

MRC Laboratory of Molecular Biology

Cambridge

2:00pm       Neuroimmune Interaction Modulation by AD Risk Factors

Li Gan PhD

Professor and Director

Helen and Robert Appel Alzheimer Disease Research Institute

Weill Cornell Medicine

3:00pm       Afternoon Break

3:15pm       The Eileen S. Trafimow Endowment

Christopher M. Gomez MD PhD

3:30pm       Role of APOE and the Immune Response in Tau-Mediated Neurodegeneration

David M. Holtzman MD

Barbara Burton and Reuben M. Morriss III Distinguished Professor

Scientific Director, Hope Center for Neurological Disorders

Dept. of Neurology

Washington University School of Medicine

4:30pm       Trans-Network Propagation and Cellular Replication of Tau Prions

Marc Diamond MD

Director and Professor

Center for Alzheimer's and Neurodegenerative Diseases

UT Southwestern Medical Center

The symposium will conclude at 5:30pm