[cid:4781ccbc-78b0-42d7-a0b2-446e84fcb0ce] Dear EMBRIO Membership, As an Institute, our collectively achieved progress toward delineating mechanisms of cellular defense and wound repair—properties vital to animal, plant, and human health and biotechnology advancements—is a testament to the power of integrating our expertise. Leveraging this momentum, we are actively assembling teams now to develop new proposals and support co-collaborator proposal writing. Please contact us as soon as possible if you are interested in participating (laddb@purdue.edu<mailto:laddb@purdue.edu>, Cc: dumulis@purdue.edu<mailto:dumulis@purdue.edu> , jzartman@nd.edu<mailto:jzartman@nd.edu> ). We are starting with an NIH RM1 for Multidisciplinary Teams<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgrants.nih.gov%2Fgrants%2Fguide%2Fpa-files%2FPAR-23-077.html&data=05%7C02%7Cembrio-list%40ecn.purdue.edu%7C5309388a15eb42c10bb308de2b7cfbbb%7C4130bd397c53419cb1e58758d6d63f21%7C1%7C0%7C638996012952274302%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=o1typFogJKTK1T%2FTFU%2BhbSfw8n0%2F4K7fp4heMPMrafc%3D&reserved=0>. For active and potential funding opportunities that align with EMBRIO 2.0 ideas, visit our proposals spreadsheet<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdocs.google.com%2Fspreadsheets%2Fd%2F1MzX5ZAyn5LjiEX5uKUm1RNz8W8URxU62%2Fedit%3Fusp%3Dsharing%26ouid%3D107962836095749734864%26rtpof%3Dtrue%26sd%3Dtrue&data=05%7C02%7Cembrio-list%40ecn.purdue.edu%7C5309388a15eb42c10bb308de2b7cfbbb%7C4130bd397c53419cb1e58758d6d63f21%7C1%7C0%7C638996012952299115%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=oN93M6ffXCgROkO0%2BlfyLWhGvLRuJm6JG4uad4wkpTY%3D&reserved=0>. Your willingness to learn, share, and tackle the challenging work of integrating ML/AI, simulation, and life-science research, along with educational research and research into the evolution of interdisciplinary identity and teams, have together made EMBRIO a paradigm for integrative discovery. This integrative effort, since late 2021 involving over a hundred investigators, staff, and trainees, has yielded impactful products and fundamental discoveries (a Summary of Outcomes<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fapp.box.com%2Fs%2Fa9bmar5joubvwweg9b7173uuhpdcjcs9&data=05%7C02%7Cembrio-list%40ecn.purdue.edu%7C5309388a15eb42c10bb308de2b7cfbbb%7C4130bd397c53419cb1e58758d6d63f21%7C1%7C0%7C638996012952317929%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=vW9qIYdBM4Ddxytkm2kvcqdJ2NU9zSP2pZBSq6e1F40%3D&reserved=0> PDF is available on our shared Box account). Perhaps the most important legacy is our trainees. The advancement of sixty-five graduate students and postdocs and sixty undergraduate researchers, at the intersection of predictive computational simulations and biology is directly supporting a growing community of practice, and the long-term growth of the U.S. Bioeconomy. Keep up the transformative research and education to make this fifth year as a Biology Integration Institute our best one yet! 🦃 Enjoy the Thanksgiving Holiday. Your EMBRIO Leadership Team, Leadership Role David Umulis Institute Co-Director Jeremiah Zartman Institute Co-Director Chris Staiger Associate Director Anjali Iyer-Pascuzzi Team Science Lead Alejandra Magana Educational Science Lead Elsje Pienaar Core Modeling Lead Janice Evans Community Advocate Lead Brent Ladd Managing Director