BME-IBSC PhD Preliminary Exam Announcement for Seul Ah Lee (Chi Hwan Lee, advisor) Everyone is invited to attend the public presentation beginning at 1:30 pm EST. Title: Development of Vision and Eye Care Device Integrated into Soft Contact Lens Date: July 28, 2022 Time: 1:30 pm EST Location: MJIS 2001 / Zoom* https://purdue-edu.zoom.us/j/98139249622 Committee: Prof. Chi Hwan Lee, Chair; Prof. Young L. Kim; Prof. Hugh Hyowon Lee; Prof. Shin Ae Park Abstract: A considerable amount of research has been done on smart contact lenses, especially as a minimally invasive diagnostic platform and a drug delivery system. The eyes provide rich physiological and broad diagnostic information, making contact lens sensors a promising disease diagnostic tool. A smart contact lens, one such contact lens sensor, can quantify the concentrations of various biomolecules in ocular fluids and physical biomarkers of the eye, such as intraocular pressure. Continuous and non- or minimally invasive contact lens sensors can be directly utilized in a clinical or point-of-care setting. However, smart contact lenses lack practicality for patient use due to the field being relatively new and underdeveloped. Here, we introduce the incorporation of contact lens sensors and their fabrication, sensitivity, power source, and readout mechanisms. The incorporation is to monitor glaucoma and conditions associated with eye health, such as dry eye syndrome and inflammation. The resulting soft contact lens sensors fit seamlessly across different corneal curvatures and thicknesses in human eyes. The lens can also wirelessly capture the intraocular pressure by utilizing the principle of the capacitor and mechanical deformation under ambulatory conditions. Also, we will discuss the colorimetric ocular electrolyte sensors to detect the color change of dry eye disease and inflammation. We assessed the in vitro biocompatibility, ex vivo functionality, and in vivo safety of the soft contact lens sensor. *Seul-Ah Lee is inviting you to a scheduled Zoom meeting. Join Zoom Meeting https://purdue-edu.zoom.us/j/98139249622 Meeting ID: 981 3924 9622 One tap mobile +13126266799,,98139249622# US (Chicago) +16469313860,,98139249622# US Dial by your location +1 312 626 6799 US (Chicago) +1 646 931 3860 US +1 301 715 8592 US (Washington DC) +1 646 558 8656 US (New York) +1 669 444 9171 US +1 669 900 6833 US (San Jose) +1 253 215 8782 US (Tacoma) +1 346 248 7799 US (Houston) Meeting ID: 981 3924 9622 Find your local number: https://purdue-edu.zoom.us/u/aer9n7SaDZ