BME-IBSC PhD Preliminary Exam Announcement for Seul Ah Lee (Chi Hwan Lee, advisor)
Everyone is invited to attend the public presentation beginning at 1:30 pm EST.
Title: Development of Vision and Eye Care Device Integrated into Soft Contact Lens
Date: July 28, 2022
Time: 1:30 pm EST
Location: MJIS 2001 / Zoom*
Committee: Prof. Chi Hwan Lee, Chair; Prof. Young L. Kim; Prof. Hugh Hyowon Lee; Prof. Shin Ae Park
Abstract:
A considerable amount of research has been done on smart contact lenses, especially as a minimally invasive diagnostic platform and a drug delivery system. The eyes provide rich physiological and broad diagnostic
information, making contact lens sensors a promising disease diagnostic tool. A smart contact lens, one such contact lens sensor, can quantify the concentrations of various biomolecules in ocular fluids and physical biomarkers of the eye, such as intraocular
pressure. Continuous and non- or minimally invasive contact lens sensors can be directly utilized in a clinical or point-of-care setting. However, smart contact lenses lack practicality for patient use due to the field being relatively new and underdeveloped.
Here, we introduce the incorporation of contact lens sensors and their fabrication, sensitivity, power source, and readout mechanisms. The incorporation is to monitor glaucoma and conditions associated with eye health, such as dry eye syndrome and inflammation.
The resulting soft contact lens sensors fit seamlessly across different corneal curvatures and thicknesses in human eyes. The lens can also wirelessly capture the intraocular pressure by utilizing the principle of the capacitor and mechanical deformation under
ambulatory conditions. Also, we will discuss the colorimetric ocular electrolyte sensors to detect the color change of dry eye disease and inflammation. We assessed the in vitro biocompatibility, ex vivo functionality, and in vivo safety of the soft contact
lens sensor.
*Seul-Ah Lee is inviting you to a scheduled Zoom meeting.
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https://purdue-edu.zoom.us/j/98139249622
Meeting ID: 981 3924 9622
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