Grad Seminar Announcement - Prof. Vorvoreanu
Purdue University School of Chemical Engineering GRADUATE SEMINAR SERIES Prof. Mihaela Vorvoreanu Purdue University "Using Social Media Strategically to Manage Your Professional Online Identity and Social Network" February 28, 2012 9:00-10:15 AM FRNY G140 Reception at 10:15 AM in Henson Atrium Abstract: This presentation addresses defensive and proactive strategies you can use to manage your online information, to use social media strategically, to promote yourself online, and to create a professional social network. Dr. V explains major social media dynamics that explain why conflicts and misunderstanding sometimes occur, and provides tips for not only avoiding misunderstandings, but also making the best of social media's networking potential. Bio: Dr. Vorvoreanu is an assistant professor in Computer Graphics Technology and Technology Leadership & Innovation at Purdue University. She studies the socio-cultural impact of new communication technologies. Before joining Purdue, she was an assistant professor in the Department of Communication Studies at Clemson University, SC, and the Department of Communication at the University of Dayton, Ohio. While at Clemson and UD respectively, Dr. Vorvoreanu taught various public relations and communication courses, and did academic research in the area of public relations and new Web technologies. She has published research articles in the Journal of New Communications Research, Public Relations Review and the Journal of Website Promotion and a book about online public relations: Web Site Public Relations: How Corporations Build and Maintain Relationships Online. Dr. Vorvoreanu holds a Ph.D. in Communication from Purdue University.
Purdue University School of Chemical Engineering GRADUATE SEMINAR SERIES Prof. Mihaela Vorvoreanu Purdue University "Using Social Media Strategically to Manage Your Professional Online Identity and Social Network" February 28, 2012 9:00-10:15 AM FRNY G140 Reception at 10:15 AM in Henson Atrium Abstract: This presentation addresses defensive and proactive strategies you can use to manage your online information, to use social media strategically, to promote yourself online, and to create a professional social network. Dr. V explains major social media dynamics that explain why conflicts and misunderstanding sometimes occur, and provides tips for not only avoiding misunderstandings, but also making the best of social media's networking potential. Bio: Dr. Vorvoreanu is an assistant professor in Computer Graphics Technology and Technology Leadership & Innovation at Purdue University. She studies the socio-cultural impact of new communication technologies. Before joining Purdue, she was an assistant professor in the Department of Communication Studies at Clemson University, SC, and the Department of Communication at the University of Dayton, Ohio. While at Clemson and UD respectively, Dr. Vorvoreanu taught various public relations and communication courses, and did academic research in the area of public relations and new Web technologies. She has published research articles in the Journal of New Communications Research, Public Relations Review and the Journal of Website Promotion and a book about online public relations: Web Site Public Relations: How Corporations Build and Maintain Relationships Online. Dr. Vorvoreanu holds a Ph.D. in Communication from Purdue University.
Purdue University School of Chemical Engineering GRADUATE SEMINAR SERIES Hoyoung Lee Purdue University "Polymer Nanotechnology Towards Improving Gene Delivery Vector Design" March 20, 2012 9:00-10:15 AM FRNY G140 Reception at 10:15 AM in Henson Atrium Abstract: The use of genetic materials (e.g., DNA and siRNA) for correcting disease-causing genes holds great potential to cure many human diseases ranging from cystic fibrosis to cancer to AIDS. However, the lack of safe and efficient gene delivery methodology remains one of the biggest challenges in transforming this idea of gene therapy into practical medicine. To address this challenge, our research focuses on applying the knowledge of polymer nanotechnology to improve our fundamental understanding of the pathway through which current gene delivery vectors are transported into cells. The ultimate goal of our research is to apply our understanding to the development of improved gene delivery vectors. In this presentation, I will present the following subjects. Firstly, I will present our work on understanding the relationship between the proton-absorbing properties of polycation-based vectors and their endosomal escape kinetics. Two model polycation systems will be compared in terms of the proton-absorbing capacity and endosomal escape kinetics. This comparison will demonstrate that the proton-absorbing properties are not directly correlated with the endosomal escape kinetics, and thus the proton-sponge effect is not the only contributing factor to the endosomal escape process. Secondly, I will present our new material development towards understanding the interrelationship between the intracellular location of DNA release and the nuclear entry/transcription level. Our research explores a novel approach that enables the release of loaded DNA at a desired intracellular location and time using a novel block copolymer micelle which is, by UV exposure, destabilized for the DNA release. Our characterization results will be presented to demonstrate this proof of concept. Lastly, I will present our X-ray and neutron reflectivity studies on the conformation of tethered PEG chains. It will be shown that PEG chains are not hydrophilic when they exist as polymer brush chains. This finding will give some insight into why the PEG brush coating ("PEGylation") in water in general so effective in preventing aggregation of the coated particles.
Purdue University School of Chemical Engineering GRADUATE SEMINAR SERIES Hoyoung Lee Purdue University "Polymer Nanotechnology Towards Improving Gene Delivery Vector Design" March 20, 2012 9:00-10:15 a.m. FRNY G140 Reception at 10:15 AM in Henson Atrium Abstract: The use of genetic materials (e.g., DNA and siRNA) for correcting disease-causing genes holds great potential to cure many human diseases ranging from cystic fibrosis to cancer to AIDS. However, the lack of safe and efficient gene delivery methodology remains one of the biggest challenges in transforming this idea of gene therapy into practical medicine. To address this challenge, our research focuses on applying the knowledge of polymer nanotechnology to improve our fundamental understanding of the pathway through which current gene delivery vectors are transported into cells. The ultimate goal of our research is to apply our understanding to the development of improved gene delivery vectors. In this presentation, I will present the following subjects. Firstly, I will present our work on understanding the relationship between the proton-absorbing properties of polycation-based vectors and their endosomal escape kinetics. Two model polycation systems will be compared in terms of the proton-absorbing capacity and endosomal escape kinetics. This comparison will demonstrate that the proton-absorbing properties are not directly correlated with the endosomal escape kinetics, and thus the proton-sponge effect is not the only contributing factor to the endosomal escape process. Secondly, I will present our new material development towards understanding the interrelationship between the intracellular location of DNA release and the nuclear entry/transcription level. Our research explores a novel approach that enables the release of loaded DNA at a desired intracellular location and time using a novel block copolymer micelle which is, by UV exposure, destabilized for the DNA release. Our characterization results will be presented to demonstrate this proof of concept. Lastly, I will present our X-ray and neutron reflectivity studies on the conformation of tethered PEG chains. It will be shown that PEG chains are not hydrophilic when they exist as polymer brush chains. This finding will give some insight into why the PEG brush coating ("PEGylation") in water in general so effective in preventing aggregation of the coated particles.
participants (1)
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Ewing, Virginia G