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ONCOLOGICAL SCIENCES CENTER
Cancer Prevention Seminar Series
Building a community interested in cancer prevention and control research.


Plasmon-resonant Nanorods as Multifunctional Imaging Agents
Presented by
Alexander Wei
Associate Professor of Chemistry
December 14, 2006
11:30 am
MRGN 121

Gold nanorods have several outstanding characteristics as optical contrast agents for biomedical imaging. Their strong optical absorption at near-infrared (NIR) frequencies can be used to generate contrast for optical coherence tomography (OCT) imaging, and is well matched for detection modalities based on differential albedo. Nanorods can also be imaged directly by two-photon luminescence (TPL) with single-particle sensitivity, and are sufficiently bright to support in vivo imaging applications. TPL imaging has been used to study the uptake of ligand-functionalized nanorods by tumor cells. Lastly, nanorods are excellent converters of light energy into heat, with direct application in photothermal therapy.


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