Dear Fellow Scientists, This December, the 3D3C facility will organize a new workshop on 3D cell culture models for projects related to the use or the development of anticancer drugs. Increasing literature reports that 3D cell culture of tumors is a more physiologically relevant in vitro model than the conventional monolayer culture. Using 3D cell culture models prior to in vivo work is predicted to boost the success rate to identify new drugs for cancer therapy and ways to circumvent resistance. However, there is a breadth of possibilities to produce tumors in culture and some techniques are better than others to recapitulate specific cell behaviors necessary for the drugs of interest. The anticancer drug testing workshop will include a lecture on the basics of drug testing in vitro and the different 3D cell culture systems to produce preinvasive and invasive tumors, classroom exercise for data analysis and presentation, and hands-on practical with tumors in culture based on different drug screening assays. The workshop will benefit those who are new to the use of anticancer drugs in vitro as well as more seasoned researchers wishing to place anticancer drug related projects in a physiologically relevant context. If you would like to have more information or attend the workshop, please feel free to contact me. Yours Sincerely Tim Kwok Facility Manager 3D Cell Culture Core (3D3C) Facility Birck Nanotechnology Center Purdue University