Dear All,
Below please find the fourteenth issue of the newsletter of the 3D Cell Culture Core (3D3C) Facility of the Birck Nanotechnology Center. The newsletter is also available online (https://nanohub.org/groups/3d3cfacility/news)
In this issue, a new section, "3D in action", is added. The five sections in the newsletter are:
3D at Purdue – this section highlights 3D cell culture-based research activity at Purdue
3D in action - this section highlights recent activity in 3D3C
3D in focus – this section presents the current work on a specific 3D cell culture model or technique
3D in publications – this section brings a collection of recent publications on 3D cell culture
3D in meetings – this section includes a list of upcoming meetings related to 3D cell culture
The newsletter will be available every two months. If you do not wish to receive the 3D3C newsletter in the future, please reply “cancel” to unsubscribe.
Please contact me if you have questions.
Yours Sincerely,
Tim Kwok
Facility Manager
3D Cell Culture Core (3D3C) Facility
Birck Nanotechnology Center
Purdue University
________________________________
[https://gallery.mailchimp.com/b7d6d1ffee56a866e499104cf/images/3e8e050f-67f…]
Volume 14, February 2018
[https://gallery.mailchimp.com/b7d6d1ffee56a866e499104cf/images/10f15e72-d4d…]
3D at Purdue
3D in Action
3D in Focus
3D in Publications
3D in Meetings
3D at Purdue
Cell-instructive Biomaterials for Musculoskeletal Soft Tissue
Regenerative Engineering
Regenerative engineering represents a new transdisciplinary paradigm to generate functional tissues and tissue systems based on Convergence of Advanced Materials Science, Stem Cell Science, Physics, Developmental Biology, and Clinical Translation. In particular, biomaterials provide an enabling technology platform to engineer a three-dimensional (3D) scaffold system offering a supportive microenvironment to direct cell migration, growth, differentiation, and organization to form regenerated tissue. The development of 3D scaffolds that mimic the hierarchical architecture of native tissue extracellular matrix requires a fundamental understanding of the structure-function relationship and cell-biomaterial interactions. The Deng Laboratory focuses on both the fundamental understanding of cellular processes in tissue development and engineering and effective biomaterial systems for musculoskeletal regenerative engineering. Our strategies for tissue regeneration embrace the mechanistic understanding of various physicochemical and biological cues on cellular processes, and the application of advanced biomaterials and matrix technologies at the micro- and nanoscale (Figure 1).
[https://gallery.mailchimp.com/b7d6d1ffee56a866e499104cf/images/49792c75-b18…]
Figure 1. Design criteria for different material cues on cell-material interactions. Physical cues, such as material topography, stiffness, and porosity, can dramatically affect cell fate and tissue development. Incorporation of chemical cues in the form of simple chemical groups into materials influences cell behavior. Additionally, material carrier presentation of various biological cues such as growth factors and small molecules/inducerons can lead to enhanced cellular responses. Integrating these cues is paramount in creating a synthetic matrix optimized for desirable cellular responses and inductive tissue regeneration (Narayanan, N., Jiang, C., Uzunalli, G., Shalumon, K.T., Laurencin, C.T., Deng, M.: Regenerative Engineering and Translational Medicine. 2016, 2(2):69-84).
In our recent collaborative work with Dr. Shihuan Kuang in Animal Sciences, we have developed a bioengineered cell niche composed of aligned polyester fiber scaffolds for skeletal muscle regeneration. Current cell-based therapies for skeletal muscle regeneration are hindered by low survival and long-term engraftment of the transplanted cells due to the lack of appropriate supportive microenvironment (cell niche) in the injured muscle. Therefore, there is a critical need for developing strategies that can provide cellular and structural support for the regeneration of new functional skeletal muscles. Inspired by the native architecture of skeletal muscle, we have created aligned polyester fiber scaffolds mimicking the oriented organization of skeletal muscle by electrospinning using a novel custom-made rotating collector made of parallel metal blades. Aligned fibers with diameters varying from 335 ± 154 nm (nanoscale) to 3013 ± 531 nm (microscale) were fabricated by varying the poly(lactide-co-glycolide) (PLGA) concentration. Myoblasts seeded on aligned PLGA fibers exhibited oriented arrangement according to the direction of fiber alignment resulting from contact guidance (Figure 2). Interestingly, microfiber scaffolds enhanced cell alignment, elongation, proliferation, and differentiation as compared to the nanofiber scaffolds indicating the ability of cells to respond to fiber topography. Pilot in vivo studies were performed to evaluate the regenerative potential of the scaffolds using a dystrophin-deficient mdx mouse model. Following 21 days of implantation, microfiber scaffolds seeded with primary myoblasts resulted in the formation of a network of dystrophin positive myofibers in tibialis anterior muscles of mdx mice. These experiments not only provide critical insights on exploiting the interactions between muscle cells and their microenvironment, but also open new avenues for the development of effective muscle regenerative technologies.
[https://gallery.mailchimp.com/b7d6d1ffee56a866e499104cf/images/d8a03b2d-de3…]
Figure 2. Fluorescence image of myoblasts on aligned fibers after 24 hours of cell seeding. Cells spread along the direction of fiber orientation on aligned scaffolds (Red: cytoskeletal actin; Blue: nuclei)
Relevant Publications:
Kumbar, S.G., Laurencin, C.T., Deng, M (Editors): Natural and Synthetic Biomedical Polymers, Elsevier, ISBN: 978-0-12-396983-5, 2014.
Narayanan, N., Jiang, C., Uzunalli, G., Shalumon, K.T., Laurencin, C.T., Deng, M.: Polymeric electrospinning for musculoskeletal regenerative engineering. Regenerative Engineering and Translational Medicine. 2016, 2(2):69-84.
Funding support from NIH R03AR068108 and Purdue Start-up Package is greatly appreciated.
Meng Deng
Assistant Professor
Department of Agricultural & Biological Engineering
________________________________
3D in Action
Workshop Invitation:
3D3C is invited to organize a workshop for Experimental Biology 2018 Annual Meeting. The workshop is scheduled on April 22, 2018. The title for the workshop is, "The Art of 3D Cell Culture, from Organoids to Organ-on-A-Chip"
Recent publication from 3D3C:
Lelièvre SA, Kwok T, Chittiboyina S. Architecture in 3D cell culture: An essential feature for in vitro toxicology Toxicol In Vitro. 2017 Dec;45(Pt 3):287-295
Abstract
Three-dimensional cell culture has the potential to revolutionize toxicology studies by allowing human-based reproduction of essential elements of organs. Beyond the study of toxicants on the most susceptible organs such as liver, kidney, skin, lung, gastrointestinal tract, testis, heart and brain, carcinogenesis research will also greatly benefit from 3D cell culture models representing any normal tissue. No tissue function can be suitably reproduced without the appropriate tissue architecture whether mimicking acini, ducts or tubes, sheets of cells or more complex cellular organizations like hepatic cords. In this review, we illustrate the fundamental characteristics of polarity that is an essential architectural feature of organs for which different 3D cell culture models are available for toxicology studies in vitro. The value of tissue polarity for the development of more accurate carcinogenesis studies is also exemplified, and the concept of using extracellular gradients of gaseous or chemical substances produced with microfluidics in 3D cell culture is discussed. Indeed such gradients-on-a-chip might bring unprecedented information to better determine permissible exposure levels. Finally, the impact of tissue architecture, established via cell-matrix interactions, on the cell nucleus is emphasized in light of the importance in toxicology of morphological and epigenetic alterations of this organelle.
________________________________
3D in Focus
The architectural and mechanical properties of a scaffold can affect cell behaviors, such as spreading, proliferation and differentiation. Stiffness, a key mechanical property, was studied mostly in systems with a single cell type. Each cell type responds to matrix stiffness in its own way and may affect the other cell types within the same biological system. Subjecting macrophages (Mφ) and bone marrow-derived mesenchymal stem cells (BMMSCs) to a stiffness-tunable matrix, the authors in the highlighted research article investigated how matrix stiffness may regulate the effect of Mφ on osteogenesis of BMMSCS.
Xiao-Tao He, Rui-Xin Wu, Xin-Yue Xu, Jia Wang, Yuan Yin, Fa-Ming Chen. Macrophage involvement affects matrix stiffness-related influences on cell osteogenesis under three-dimensional culture conditions. Acta Biomaterialia https://doi.org/10.1016/j.actbio.2018.02.015
3D3C summary of the article: Transglutaminase cross-linked gelatin (TG-gel) with different stiffness levels were prepared by crosslinking different percentages of gelatin with transglutaminase, 3% (Low), 6% (Mid) and 9% (High). The stiffness of TG-gel increased and the porosity decreased with an increase in the percentage of gelatin. Both proliferation and viability of BMMSCs were higher in low-stiffness TG-gels than in high-stiffness TG-gel. The osteogenic potential of the BMMSCs, assessed by Alizarin Red S staining of mineralized nodules, release of alkaline phosphatase (ALP), and the expression levels of osteogenic genes (SP7, OST, RUNX2, ALP and OCN) were elevated with an increase in matrix stiffness. In response to microenvironmental signals, Mφ undergo polarization into distinct functional cells, M1, M2 cells. The polarization status of the Mφ in matrices with different stiffness levels were analyzed via qRT-PCR, immunofluorescence and ELISA. The expression levels of M1-related markers (IL-1β and TNF-α) increased proportionally with an increase in stiffness of the TG-gel.
Mφ effects on osteogenesis of BMMSCs cultured in different stiffness levels of TG-gel were examined in a Transwell co-culture system, in which gel-encapsulated Mφ were placed in the upper compartment, and the BMMSCs were in the bottom compartment. The ALP activity and the formation of mineralized nodules in non-encapsulated monolayers of BMMSCs were enhanced when these cells were incubated with Mφ encapsulated in low-stiffness gel compared to high-stiffness gel. Mφ encapsulated in low-stiffness TG-gel increased the formation of mineralized nodules and the ALP activity in BMMSCs encapsulated in either low- or high-stiffness TG-gels, whereas Mφ in high-stiffness TG-gel suppressed these phenomena. By encapsulating Mφ (in the upper compartment) and BMMSCs (in the bottom compartment) in TG-gel of the same stiffness level, the BMMSCs in low- and high-TG-gel displayed higher ALP activity and mineralized nodules formation than the BMMSCSs in mid-stiffness TG-gel, suggesting the nonlinear influence of stiffness for the effect of on BMMSCs osteogenesis.
Comments from 3D3C: Extracellular matrix stiffness has profound impacts on cell function and differentiation. Most of the studies related to stiffness are performed, however, on culture systems with a single cell type, while multiple cell types are present in vivo. By encapsulating BMMSCs and Mφ in TG-gel with different stiffness levels in separate chambers of a Transwell system, the studies presented here argue against the conventional rationale that data obtained from a study with a single cell type reflect what happens in vivo where multiple cell types are present. In addition, the possibility that stiffness might vary locally (e.g., next to a particular cell type compared to another cell type) in vivo should also be explored, as results here suggested that the result of the interaction between different cell types might depend on their respective environmental stiffness. An important aspect to explore in future experiment is how the cells would influence each other if placed in the same culture, a system that would better mimics in vivo conditions.
________________________________
3D in Publications
Recent publications on 3D culture (please click to access the list on our web page
https://nanohub.org/groups/3d3cfacility)
Review<https://nanohub.org/groups/3d3cfacility/news#reviews>
The research articles and reviews are arranged in the following categories:
Scaffold free/Scaffold
Organ/Tissue/Cell
Others
Spheroids<https://nanohub.org/groups/3d3cfacility/news#spheroids>
Organoid<https://nanohub.org/groups/3d3cfacility/news#organoid>
Scaffold<https://nanohub.org/groups/3d3cfacility/news#scaffold>
Hydrogel<https://nanohub.org/groups/3d3cfacility/news#hydrogel>
Matrix<https://nanohub.org/groups/3d3cfacility/news#matrix>
Microfluidics<https://nanohub.org/groups/3d3cfacility/news#microfluidic>
Microfabrication<https://nanohub.org/groups/3d3cfacility/news#microfabrication>
Bone<https://nanohub.org/groups/3d3cfacility/news#bone>
Bone Marrow<https://nanohub.org/groups/3d3cfacility/news#bonemarrow>
Breast<https://nanohub.org/groups/3d3cfacility/news#breast>
Colon<https://nanohub.org/groups/3d3cfacility/news#colon>
Heart<https://nanohub.org/groups/3d3cfacility/news#heart>
Liver<https://nanohub.org/groups/3d3cfacility/news#liver>
Lung<https://nanohub.org/groups/3d3cfacility/news#lung>
Muscle<https://nanohub.org/groups/3d3cfacility/news#muscle>
Nerve<https://nanohub.org/groups/3d3cfacility/news#nerve>
Prostate<https://nanohub.org/groups/3d3cfacility/news#prostate>
Endothelial cells<https://nanohub.org/groups/3d3cfacility/news#endothelialcells>
Fibroblast<https://nanohub.org/groups/3d3cfacility/news#fibroblast>
Stem Cells<https://nanohub.org/groups/3d3cfacility/news#stemcells>
Stromal Cells<https://nanohub.org/groups/3d3cfacility/news#stromalcells>
Cancer/Tumor<https://nanohub.org/groups/3d3cfacility/news#cancer>
Screening<https://nanohub.org/groups/3d3cfacility/news#screening>
3D bioprinting<https://nanohub.org/groups/3d3cfacility/news#3dbioprinting>
Imaging<https://nanohub.org/groups/3d3cfacility/news#imaging>
________________________________
3D in Meetings
Keystone Symposia: Organs- and Tissues-on-Chips
Date: 8th to 12th April 2018
Location: Big Sky, Montana, USA
Website: http://www.keystonesymposia.org/18D1
Contact person:info@keystonesymposia.org
Organized by: Keystone Symposia
3rd International Conference on Nanomedicine, Drug Delivery, and Tissue Engineering (NDDTE'18)
Date: 10th to 12th April 2018
Location: New Delhi, India
Website: http://nddte.com/
Contact person: Conference Administrator
Organized by: International ASET
3rd International Conference on 3D Printing in Medicine
Date: 4th to 5th May 2018
Location: Halle, Germany
Website: http://3dprint-congress.com/
Contact person:congress@bb-mc.com
Organized by: boeld communication GmbH
2nd World Congress and Expo on Nanotechnology and Materials Science
Date: 25th to 27th June 2018
Location: Dubai, United Arab Emirates
Website: https://biocoreconferences.com/nanotechnology2018/index.php
Contact person: Hany
Organized by: Biocore
4th International Conference on Bio-based Polymers and Composites
Date: 2nd to 6th September 2018
Location: Balatonfüred, Hungary
Website: http://www.bipoco2018.hu
Contact person: Dóra Tátraaljai
Bio-based polymers and their blends, composites. Natural polymers and their modification. Natural fiber reinforced composites. Other raw materials based on natural resources. Biodegradation and environmental issues
EMBO|EMBL Symposium: Organoids: Modelling Organ Development and Disease in 3D Culture
Date: 10th to 13th September 2018
Location: Heidelberg, Germany
Website: http://www.embo-embl-symposia.org/symposia/2018/EES18-08/index.html
Contact person: events(a)embl.de<mailto:events@embl.de>
Organized by: EMBL
[BIRCK NANOTECHNOLOGY CENTER][http://www.purdue.edu/discoverypark/resources/toolkit/files/logo/di…]
Seminars/Workshops
Matthew L. Becker Seminar
Building bone with polymers- How new materials and additive manufacturing are changing medicine
April 5th @ 2:00pm in BRK 1001
http://www.purdue.edu/discoverypark/birck/events/index.php?view=1420
See other Discovery Park's Events:
http://www.purdue.edu/discoverypark/events/index.php
Birck Nanotechnology Center PM Shut Down Notice
The Birck Nanotechnology Center will be undergoing a semi-annual preventive maintenance and service shutdown April 30 through May 4, 2018. Air handling systems, exhaust systems, toxic gas delivery, and monitoring systems will be down beginning at 7 a.m. Monday, April 30 through 4 p.m. Friday, May 4. The BNC staff will be performing appropriate preventive maintenance on the process equipment at this time as well.
All CLEANROOM research work will be suspended until the maintenance activities are completed and all systems are returned to normal. Only authorized personnel will be allowed to enter the cleanroom during this time period.
In addition, the laboratory areas will also be affected by this systems maintenance. As such, all LABORATORY activities that involve exhausted hoods, vacuum systems, and/or toxic gas systems will be down beginning 7 a.m. Monday, April 30 through 4 p.m. Friday, May 4. However, work that involves taking standard electrical measurements may be carried out in the LABS provided that fluctuating air temperature and humidity do not affect the readings. No chemical work will be allowed during this period.
It is anticipated that the building and process tool maintenance will be completed by the end of the day on Friday, May 4. Please check iLabs for equipment status and availability.
For long term research planning please refer the following future dates for our future preventive maintenance shutdowns.
Week of Oct 15, 2018 Week of April 29, 2019
Week of Oct 14, 2019 Spring May 4, 2020
Thank you for your cooperation and understanding during these important preventive maintenance shutdowns.
Mark Voorhis
Building Manager
Birck Nanotechnology Center
Nanodays 2018 Volunteer Sign-Up
Purdue's Birck Nanotechnology Center has an exciting volunteer opportunity for students in the technical, education, and management fields. Participants will have the opportunity to:
* Gain professional experience explaining scientific concepts to people from non-technical backgrounds.
* Support the future of STEM programs by introducing grade schoolers and high school students to the miniscule world of atoms, molecules, and nanoscale forces.
* Participate with other students/researchers in a nationwide festival celebrating nanotechnology science and education.
Since 2010, the Birck Nanotechnology Center at Discovery Park has participated in NISE NanoDays, a program that promotes science and technology education nationwide. Volunteers will staff activity stations and assist visitors as they investigate different scientific concepts. Some example activities for 2018 include gummy capsules, ferrofluids, invisibility, thin film bookmarks, oobleck, and UV bead bracelets. No prior knowledge is required to volunteer, just an enthusiasm for science and science education.
Local vendors will be providing food for volunteer training and all three days of the event.
Volunteers can attend any or all of the following shifts:
Wed 4/11/18: 5:30 PM - 8:00 PM
Thu 4/12/18: 8:45 AM - 11:30 AM
11:15 AM - 2:00 PM
Fri 4/13/18: 8:45 AM - 11:30 AM
11:15 AM - 2:00 PM
Training is mandatory and will be provided in the Birck atrium. The schedule is:
Tue 4/03/18: 5:00 PM - 5:30 PM (Pizza Party)
5:30 PM - 6:30 PM (Training Sessions)
Interested volunteers can sign up here: https://tinyurl.com/ycnov92z
A full activity list can be found here: https://tinyurl.com/yacebhpu
Questions can be directed to volunteer coordinators Joon Park (park218(a)purdue.edu<mailto:park218@purdue.edu>), Justin Wirth (jcwirth(a)purdue.edu<mailto:jcwirth@purdue.edu>), and Sean Rinehart (srinehar(a)purdue.edu<mailto:srinehar@purdue.edu>).
Important Procurement Transition Process
We have been communicating for some time that Purdue is undergoing a campus wide transformation process related to many aspects of our daily work life. The finance module of this project is set to "go-live" on July 1st, 2018. This transformation will redesign the core financial structure to a standardized structure that allows us to truly utilize SAP. In order to prepare for this transition, there will be a period of time where we will not be allowed to place orders through Ariba.
IMPORTANT DATES:
* April 18th - Any orders greater than $10K have to be submitted and approved in Ariba
* May 9th - Final day for ALL OTHER Ariba orders to be submitted - "requester role" will be removed from all who have access
* May 10th - July 1st:
* P-cards will be used for purchases that are considered low-risk/small transactions. Our credit card limits will be increased to account for the increase in transactions.
* Direct Payments can be used when a vendor will not accept credit cards during this time frame. However, direct payment submitted after June 1st will not be submitted to the vendor until AFTER July 1st.
* For high risk/capital equipment a form 12 will need to be submitted to the procurement help desk so that the appropriate authorizations can be obtained via DocuSign.
BEST PRACTICES FOR TRANSITION PERIOD:
* If you plan on ordering a piece of capital equipment, please obtain all necessary documentation and approvals and enter the PO no later than 4/18.
* If you routinely purchase certain items or have specific orders scheduled for May or June, please place those orders now.
* Long-term or multi-year projects should be broken down into multiple POs with the first phase anything that would need paid out prior to the end of June.
* If you have a situation that you are unsure of, please discuss with the business office.
If you have ANY questions or concerns, please let me know.
Thank you all for your understanding on this matter.
/////////////////////////////////////////
Erica Cox
Business Manager
Birck Nanotechnology Center
1205 W. State Street
West Lafayette, IN 47907
[New DP Logo B&G]
* ericacox(a)purdue.edu<mailto:ericacox@purdue.edu>
( 765-494-1619
Reminder: Parking Facilities in new location
Parking Facilities recently relocated from the Purdue West Shopping Plaza to the Materials Management and Distribution Center (MMDC). The new site is co-located with Transportation Service at 700 Ahlers Drive, near the intersection of South Russell Street and Ahlers Drive in West Lafayette.
Phone numbers and email addresses for staff remain the same. Parking Facilities can be reached at (765) 494-9497 or parking(a)purdue.edu<mailto:parking@purdue.edu> from 7:30 a.m. to 4:30 p.m. Monday through Friday.
Aspire Four Week Look Ahead Schedule
Attached is the Aspire Four Week Look Ahead Schedule. It is the projection of vibration and/or noise issues with the construction outside of Birck.
Dear All,
FYI see below seminar announcement later this morning.
Best regards,
Ali
**********
Professor Holger Schmidt Seminar
Optofluidic integration of hollow-core waveguides for chip-based biomolecule analysis
March 20th @ 10:00am in MRGN 129
http://www.purdue.edu/discoverypark/birck/events/index.php?view=1392
Optofluidic integration of hollow-core waveguides for chip-based biomolecule analysis
Bio: Holger Schmidt received the Ph.D. degree in electrical and computer engineering from the University of California Santa Barbara. He served as a Postdoctoral Fellow at M.I.T. He is currently the Narinder Kapany Chair of Optoelectronics and Professor of Electrical Engineering at UC Santa Cruz. Hthe e also serves as the Associate Dean for Research in Baskin School of Engineering and the Director of the W.M. Keck Center for Nanoscale Optofluidics. His research interests cover a broad range in photonics and integrated optics, including optofluidic devices, atom photonics, nano-magneto-optics, spintronic devices, and ultrafast optics. He has authored more than 400 publications, several book chapters, and co-edited the CRC Handbook of Optofluidics. He is a Fellow of the IEEE and the Optical Society of America, and received an NSF Career Award and a Keck Futures Nanotechnology Award.
Abstract: Integrated photonic devices have traditionally been designed for data communications using exclusively solid-state materials. However, a vast area of potential applications, in particular in the life sciences, involve interactions of light with liquids and gases. Recently, a number of optofluidic approaches have been considered that are aimed at integrating such non-solid media with chip-scale photonic structures. We have developed a versatile, planar photonic platform based on hollow-core optical waveguides (ARROWs). I will describe the physical foundations and optical characteristics of ARROWs and a broad range of devices and capabilities that are made possible by this approach, in particular optical analysis of single biomolecules. One example is the fluorescence analysis of single nucleic acids for amplification-free detection of Ebola infection as a new paradigm for molecular diagnostics. I will also describe the implementation of optofluidic wavelength division multiplexing in multi-mode waveguides for identification of single influenza viruses. The expansion of optofluidic capabilities through hybrid integration via nanopore-based electrical detection and integrated sample processing will be discussed. Finally, I will introduce a new, highly reconfigurable photonic platform based on lightvalves that enable independent, dynamic control of fluid and light flow on a chip.
[BIRCK NANOTECHNOLOGY CENTER][http://www.purdue.edu/discoverypark/resources/toolkit/files/logo/di…]
Seminars/Workshops
Nanomanufacturing Preeminent Team Seminar - Deblina Sarkar
Green Electronics to Gray Matter: Ghost Walks, Mind Blowing and Brain Doping
March 19th @ 2:00pm in BRK 2001
http://www.purdue.edu/discoverypark/birck/events/index.php?view=1404
Professor Holger Schmidt Seminar
Optofluidic integration of hollow-core waveguides for chip-based biomolecule analysis
March 20th @ 10:00am in MRGN 129
http://www.purdue.edu/discoverypark/birck/events/index.php?view=1392
Nanomanufacturing Preeminent Team Seminar - Shideh Kabiri Ameri
Graphene Based Wearables and Sensors
March 21st @ 9:30am in BRK 2001
http://www.purdue.edu/discoverypark/birck/events/index.php?view=1391
Professor Hui Cao Seminar
Complex Nanophotonics
March 23rd @ 9:30am in WANG 1004
http://www.purdue.edu/discoverypark/birck/events/index.php?view=1403
Workshop on Nanomaterials Characterization
Birck Nanotechnology Center is excited to hold a workshop in conjunction with three research-oriented companies - NT-MDT, Quantum Design, and Gatan - which supply crucial equipment at the Birck facility.
March 22-23, 2018
https://www.eventbrite.com/e/nanomaterials-characterization-workshop-regist…
See other Discovery Park's Events:
http://www.purdue.edu/discoverypark/events/index.php
Nanodays 2018 Volunteer Sign-Up
Purdue's Birck Nanotechnology Center has an exciting volunteer opportunity for students in the technical, education, and management fields. Participants will have the opportunity to:
* Gain professional experience explaining scientific concepts to people from non-technical backgrounds.
* Support the future of STEM programs by introducing grade schoolers and high school students to the miniscule world of atoms, molecules, and nanoscale forces.
* Participate with other students/researchers in a nationwide festival celebrating nanotechnology science and education.
Since 2010, the Birck Nanotechnology Center at Discovery Park has participated in NISE NanoDays, a program that promotes science and technology education nationwide. Volunteers will staff activity stations and assist visitors as they investigate different scientific concepts. Some example activities for 2018 include gummy capsules, ferrofluids, invisibility, thin film bookmarks, oobleck, and UV bead bracelets. No prior knowledge is required to volunteer, just an enthusiasm for science and science education.
Local vendors will be providing food for volunteer training and all three days of the event.
Volunteers can attend any or all of the following shifts:
Wed 4/11/18: 5:30 PM - 8:00 PM
Thu 4/12/18: 8:45 AM - 11:30 AM
11:15 AM - 2:00 PM
Fri 4/13/18: 8:45 AM - 11:30 AM
11:15 AM - 2:00 PM
Training is mandatory and will be provided in the Birck atrium. The schedule is:
Tue 4/03/18: 5:00 PM - 5:30 PM (Pizza Party)
5:30 PM - 6:30 PM (Training Sessions)
Interested volunteers can sign up here: https://tinyurl.com/ycnov92z
A full activity list can be found here: https://tinyurl.com/yacebhpu
Questions can be directed to volunteer coordinators Joon Park (park218(a)purdue.edu<mailto:park218@purdue.edu>), Justin Wirth (jcwirth(a)purdue.edu<mailto:jcwirth@purdue.edu>), and Sean Rinehart (srinehar(a)purdue.edu<mailto:srinehar@purdue.edu>).
Important Procurement Transition Process
We have been communicating for some time that Purdue is undergoing a campus wide transformation process related to many aspects of our daily work life. The finance module of this project is set to "go-live" on July 1st, 2018. This transformation will redesign the core financial structure to a standardized structure that allows us to truly utilize SAP. In order to prepare for this transition, there will be a period of time where we will not be allowed to place orders through Ariba.
IMPORTANT DATES:
* April 18th - Any orders greater than $10K have to be submitted and approved in Ariba
* May 9th - Final day for ALL OTHER Ariba orders to be submitted - "requester role" will be removed from all who have access
* May 10th - July 1st:
* P-cards will be used for purchases that are considered low-risk/small transactions. Our credit card limits will be increased to account for the increase in transactions.
* Direct Payments can be used when a vendor will not accept credit cards during this time frame. However, direct payment submitted after June 1st will not be submitted to the vendor until AFTER July 1st.
* For high risk/capital equipment a form 12 will need to be submitted to the procurement help desk so that the appropriate authorizations can be obtained via DocuSign.
BEST PRACTICES FOR TRANSITION PERIOD:
* If you plan on ordering a piece of capital equipment, please obtain all necessary documentation and approvals and enter the PO no later than 4/18.
* If you routinely purchase certain items or have specific orders scheduled for May or June, please place those orders now.
* Long-term or multi-year projects should be broken down into multiple POs with the first phase anything that would need paid out prior to the end of June.
* If you have a situation that you are unsure of, please discuss with the business office.
If you have ANY questions or concerns, please let me know.
Thank you all for your understanding on this matter.
/////////////////////////////////////////
Erica Cox
Business Manager
Birck Nanotechnology Center
1205 W. State Street
West Lafayette, IN 47907
[New DP Logo B&G]
* ericacox(a)purdue.edu<mailto:ericacox@purdue.edu>
( 765-494-1619
Aspire Four Week Look Ahead Schedule
Attached is the Aspire Four Week Look Ahead Schedule. It is the projection of vibration and/or noise issues with the construction outside of Birck.
[BIRCK NANOTECHNOLOGY CENTER][http://www.purdue.edu/discoverypark/resources/toolkit/files/logo/di…]
Seminars/Workshops
Workshop on Nanomaterials Characterization
Birck Nanotechnology Center is excited to hold a workshop in conjunction with three research-oriented companies - NT-MDT, Quantum Design, and Gatan - which supply crucial equipment at the Birck facility.
March 22-23, 2018
https://www.eventbrite.com/e/nanomaterials-characterization-workshop-regist…
See other Discovery Park's Events:
http://www.purdue.edu/discoverypark/events/index.php
Nanodays 2018 Volunteer Sign-Up
Purdue's Birck Nanotechnology Center has an exciting volunteer opportunity for students in the technical, education, and management fields. Participants will have the opportunity to:
* Gain professional experience explaining scientific concepts to people from non-technical backgrounds.
* Support the future of STEM programs by introducing grade schoolers and high school students to the miniscule world of atoms, molecules, and nanoscale forces.
* Participate with other students/researchers in a nationwide festival celebrating nanotechnology science and education.
Since 2010, the Birck Nanotechnology Center at Discovery Park has participated in NISE NanoDays, a program that promotes science and technology education nationwide. Volunteers will staff activity stations and assist visitors as they investigate different scientific concepts. Some example activities for 2018 include gummy capsules, ferrofluids, invisibility, thin film bookmarks, oobleck, and UV bead bracelets. No prior knowledge is required to volunteer, just an enthusiasm for science and science education.
Local vendors will be providing food for volunteer training and all three days of the event.
Volunteers can attend any or all of the following shifts:
Wed 4/11/18: 5:30 PM - 8:00 PM
Thu 4/12/18: 8:45 AM - 11:30 AM
11:15 AM - 2:00 PM
Fri 4/13/18: 8:45 AM - 11:30 AM
11:15 AM - 2:00 PM
Training is mandatory and will be provided in the Birck atrium. The schedule is:
Tue 4/03/18: 5:00 PM - 5:30 PM (Pizza Party)
5:30 PM - 6:30 PM (Training Sessions)
Interested volunteers can sign up here: https://tinyurl.com/ycnov92z
A full activity list can be found here: https://tinyurl.com/yacebhpu
Questions can be directed to volunteer coordinators Joon Park (park218(a)purdue.edu<mailto:park218@purdue.edu>), Justin Wirth (jcwirth(a)purdue.edu<mailto:jcwirth@purdue.edu>), and Sean Rinehart (srinehar(a)purdue.edu<mailto:srinehar@purdue.edu>).
Lesker Evaporator Available for Depositions
We are pleased to report that the Lesker evaporator has been thoroughly cleaned and is available for depositions. In order to maintain a very clean system the Birck Staff and Management have decided to keep the Lesker as a staff-only use machine. The staff will complete your depositions for you at no extra charge and this will enable us to keep at least one chamber clean for good Ti, Cr, Au, Ni, Al ,and Ni depositions. We have run into continuing problems with organic materials being placed in the system which continues to contaminate it. To schedule a deposition in the Lesker simply send an email to Dave or Kenny and they would be more than happy to run your samples for you.
Contacts: Dave Lubelski (lubelski(a)purdue.edu<mailto:lubelski@purdue.edu>), Kenny Schwartz (kfschwar(a)purdue.edu<mailto:kfschwar@purdue.edu>)
Aspire Four Week Look Ahead Schedule
Attached is the Aspire Four Week Look Ahead Schedule. It is the projection of vibration and/or noise issues with the construction outside of Birck.
![CENTER][http://www.purdue.edu/discoverypark/resources/toolkit/files/logo/di…](http://CENTER][http://www.purdue.edu/discoverypark/resources/toolkit/files/logo/digital/Logo-949x222.png){kind=link}