[cid:image001.jpg@01DA9A1E.76EF94C0] BME WEEKLY ROUNDTABLE April 29, 2024 FINALS WEEK! INTERIM HEAD'S NOTE First of all, I wish all of you good luck in the finals week (taking final exams, proctoring and grading final exams, etc.). Special best-wishes to the graduate students who are going through their milestones (prelim, defense, etc.) in the coming days. Following what I did in last week's note, I want to highlight more accomplishments of our faculty and students. Congratulations! Much appreciation is sent to all the faculty, postdocs, graduate students who nominated our wonderful undergraduate students, wrote support letters for them, and more importantly teach, mentor, and provide academic and professional development opportunities to them. * Dr. Taimoor Hassan Qazi received the Outstanding Mentor of Engineering Award. * Ana Claure Dips received the National Science Foundation Graduate Research Fellowship. * Andrew Gangstad received the Purdue G.A. Ross Award. * Dean Stornello received the Bruce Helfert Memorial Award * Many more to come. Here is a highlight of upcoming events. * BME mini-retreat, Lafayette Country Club, May 3 at 2 - 5 pm. Please come out to have fun with 40+ of your colleagues. There will be fun and surprises. There will be prizes to give away. * BME Graduate Celebration Class of 2024, MJIS Atrium, May 11 at 9 - 11:30 am. Our graduating students, their families and friends are all invited. Faculty and graduate students, you are also invited. Come out to celebrate the graduation with them, especially those whom you have helped. Here is a friendly reminder. Jo sent out an email last week on behalf of Vitaliy in regard to teaching history and projection. Based on the discussions of the working group for teaching, we have provided you with an Excel table showing previous and current teaching assignments, from Fall 2019 to Fall 2024. This is a living document that will be updated and kept available to all Weldon School instructors. Your comments and suggestions are welcome. Finally, a quick update on the IUPUI integration. Our BME unit in Indy is pretty much spared from office moving for their faculty. There will not be pending moves of our offices there, except for a few who have received administrative appointments. Joey Wallace, appointed as the Site Director, is helping us. Many thanks to him providing valuable assistance to all of us navigating these final steps of this integration process. UPCOMING IMPORTANT DATES Week of April 29 Mon., April 29: BME PhD Preliminary Exam Announcement for Thejas Vishnu Ramesh (J. Rispoli and V. Rayz, advisors). Everyone is invited to attend the public presentation beginning at 2:00 PM in MJIS 2001 and via Zoom. Research title: Conductive fabric based wearable coil for cervical spine and carotid arteries MRI at 3T. Mon., April 29: Center for Diabetes and Metabolic Diseases Enrichment Seminar Series, 12:00 noon, R4-101 (Indianapolis) and via Zoom. Sangeeta Dhawan, PhD, Associate Professor of Translational Research and Cellular Therapeutics, Arthur Riggs Diabetes and Metabolism Research Institute, City of Hope, Duarte, CA will present "Learning the Epigenetic Secrets of Islet Development to Understand Beta Cell Failure in Diabetes. This seminar is sponsored by the Center for Diabetes and Metabolic Diseases, IU School of Medicine. Zoom link: https://iu.zoom.us/j/87501979533#success<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fiu.zoom.us%2Fj%2F87501979533%23success&data=05%7C02%7Cbmeroundtable-list%40ecn.purdue.edu%7C529609247f2141fdb9db08dc68572147%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638499970668870273%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=Ghx21z3fZzVj1QVM8KDGkP8LYpNkNd3hNsv04WQWH%2BE%3D&reserved=0> Tues., April 30: Neil Armstrong Distinguished Visiting Professors, 3:00 p.m., WALC 1018. Dr. Ronald Latanision, Senior Fellow, Exponent, Inc. and Neil Armstrong Distinguished Visiting Professor, School of Industrial Engineering, will present "The Evolution of the Materials Genome Initiative." There will be a reception following the seminar, from 4:00-4:30 p.m. More information at https://engineering.purdue.edu/NADVP?utm_source=delivra&utm_medium=email&utm... Wed., May 1: Weldon School 2024-2025 GTA Nominations Due. We are excited to begin our recruitment of Graduate Teaching Assistants (GTAs) for the upcoming 2024-25 academic year. The process involves faculty nominations via the survey link below for your graduate students. Please complete the survey by May 1st for consideration of your student(s) for a GTA role and funding: https://purdue.ca1.qualtrics.com/jfe/form/SV_3wSzp9BFQyoeW8K<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca1.qualtrics.com%2Fjfe%2Fform%2FSV_3wSzp9BFQyoeW8K&data=05%7C02%7Cbmeroundtable-list%40ecn.purdue.edu%7C529609247f2141fdb9db08dc68572147%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638499970668870273%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=5i6whcqedcM0sUvHoIS%2BGljBl8dJ3JAAgm%2BoRwRPC8E%3D&reserved=0> Assignments will be made based on overall needs for each course and experience/performance of each candidate. Following the faculty nomination process, assignments will be made in early summer and notifications of placements are expected to be sent in June. If you have any questions, please feel free to contact me (aboelzahab@purdue.edu<mailto:aboelzahab@purdue.edu>). Additionally, if you have any international students who have not yet taken the OEPT (Oral English Proficiency Test), please have them reach out to me to schedule this as slots remain available. Thurs., May 2: BME Master's Defense Announcement for Adalyn Meeks (Craig Goergen, advisor). Everyone is invited to attend the public presentation beginning at 2:00 PM EST in MJIS 2001 and via Zoom. Title: High-Frequency Murine Ultrasound of Microrobot Drug Delivery Systems and Cardiac Effects of Hypertension During Pregnancy. Thurs., May 2: Neil Armstrong Distinguished Visiting Professors, 2:40-3:20 p.m., STEW 218. Professor Mordechai Segev, Robert J. Shillman Distinguished Professor of Physics and Electrical Engineering, Technion, Israel, and Neil Armstrong Distinguished Visiting Professor, The Elmore Family School of Electrical and Computer Engineering, Purdue will present "Light-Matter Interactions in Photonic Time-Crystals" as part of the 4th Annual Quantum Summer School, The Quantum Science Center, hosted by Purdue. For more information: https://engineering.purdue.edu/NADVP?utm_source=delivra&utm_medium=email&utm... MJIS END OF SEMESTER ALERTS/REMINDERS Just a quick reminder of a few MJIS policies as we approach the chaos that is the end of the semester. (1) Do not give access (e.g., open a door, prop a door) to anyone you do not know into the secure lab block or any office or meeting room. If there is someone you do not recognize, feel free to call/text Susan Hardy and let her know. Vendors or service personnel should always be invited and escorted by a BME staff or faculty member, and should not be in the building after (or before) normal working hours. Purdue service personnel should always identify themselves and their purpose for being in MJIS. (2) Do not leave office doors unlocked or personal items (backpacks, purses, laptops) unattended. Unfortunately, this is the time of year when individuals come on to our campus to take advantage of distractions associated with the semester ending. We have had personal items stolen in the past. Don't become a victim! GRADING DEADLINES Dear BME faculty, It's crazy to believe the end of the Spring term is just around the corner and final grading opens THIS WEEK. This is the perfect time to ensure your web certifications are current so you don't get stuck during a deadline. FERPA, GLBA, Protecting SSNs, and Data Handling all must be current at the time of grade entry to prevent any roadblocks. Full Term (meets January 8 through May 4) and Second Eight Weeks (meets March 4 through May 4) Grade entry begins at 8 a.m. April 22 and ends at 5 p.m. May 7. Grading Instructions INB or myPurdue grading instructions are here: https://www.purdue.edu/registrar/faculty/gradingPWL-grade-entry-update.html<https://www.purdue.edu/registrar/faculty/grading/PWL-grade-entry-update.html>. The full grading policy can be found here: https://catalog.purdue.edu/content.php?catoid=16&navoid=19719#grades-and-gra... Grading questions: Contact the Office of the Registrar by calling (765) 494-6165 or sending an e-mail to registrar@purdue.edu<mailto:registrar@purdue.edu> Upcoming important deadlines and information Tues., May 7: BME PhD Defense Announcement for Vidhya Vijayakrishnan Nair (Yunjie Tong, advisor). Everyone is invited to attend the public presentation beginning at 9:00 AM in MJIS 2001 and via Zoom. Research title: Human Cerebrospinal Fluid Movement across Wake and Sleep States - A Multimodal Imaging Study Wed., May 8: BME PhD Defense Announcement for Yilun Li (Fang Huang, advisor). Everyone is invited to attend the public presentation beginning at 10:00AM EST in FLEX B038 or via Zoom. Title: A user-centric cloud computation platform for super-resolution imaging reconstruction. Thurs., May 9: IBSC-BME Preliminary Exam Announcement for Eric J. Tan (Tamara Kinzer-Ursem, advisor), 2:30 p.m., MJIS 2001. This preliminary exam is open only to those who have signed the Lilly NDA. Title: Developing ultrasensitive point-of-care detection of hyper-phosphorylated tau in patients with preclinical Alzheimer's disease. Committee: Tamara L. Kinzer-Ursem, Chair; Jacqueline Linnes; Jean-Christophe Rochet; Scott C. Bolton Fri., May 10: Deadline for Registration for 2024 Hitchhiker's Guide to the Biomolecular Galaxy, to be held Thursday, May 23-Friday, May 24 in Armstrong Hall. ! Please register using this link<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fqualtricsxmmx7jkjmbp.qualtrics.com%2Fjfe%2Fform%2FSV_7aoqAK53GeyeKMu&data=05%7C02%7Cbmeroundtable-list%40ecn.purdue.edu%7C529609247f2141fdb9db08dc68572147%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638499970668870273%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=Yeel8PMCKG%2B9XGTU%2BU6VG6hcaVKut0wbY1OxZTvT6hc%3D&reserved=0>. If you would like to present an oral presentation or poster, please submit an abstract when registering. Awards will be given to the Top 3 posters and oral presentations, with a People's Choice award at the end of the second day. Thurs., May 23-Fri., May 24: 2024 Hitchhiker's Guide to the Biomolecular Galaxy, Armstrong Hall. Registration is officially open for the 2024 Hitchhiker's Guide to the Biomolecular Galaxy! Please register using this link<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fqualtricsxmmx7jkjmbp.qualtrics.com%2Fjfe%2Fform%2FSV_7aoqAK53GeyeKMu&data=05%7C02%7Cbmeroundtable-list%40ecn.purdue.edu%7C529609247f2141fdb9db08dc68572147%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638499970668870273%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=Yeel8PMCKG%2B9XGTU%2BU6VG6hcaVKut0wbY1OxZTvT6hc%3D&reserved=0>. Hitchhiker's Guide to the Biomolecular Galaxy Symposium brings together undergraduate students, graduate students, post-doctorates, and faculty throughout the Midwest who are all striving to share and gain more insight into various biophysical approaches. Registration is completely free with breakfast, lunch, coffee, and snacks provided both days. The symposium will include a keynote address given by Dr. Jin Zhang from the University of California San Diego. Dr. Zhang's research lab developed a series of molecular tools and fluorescence imaging technologies to understand the spatiotemporal regulation of cell signaling. <https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fjinzhanglab.ucsd.edu%2F&data=05%7C02%7Cbmeroundtable-list%40ecn.purdue.edu%7C529609247f2141fdb9db08dc68572147%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638499970668870273%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=g%2BlBHl8tQ0I4GxxriSxyZ1w%2Bt9Y6lPpqMwBNs46V1NE%3D&reserved=0> Fri., June 7: Indiana Human-Centered Design for Health Seminar Series, 12:00 p.m. via Zoom. Lean about research and best practices in HCD and health, promote the diverse HCD expertise in Indiana, and build a community of HCD researchers and practitioners focused on health, in Indiana and beyond. The speaker will be Youngbok Hon, Professor, Herron School of Art and Design, IUPUI. Register and learn about upcoming seminars at healthtechquitylab.org/hcd-seminar Resources and further information Mon., April 29: BME PhD Preliminary Exam Announcement for Thejas Vishnu Ramesh (J. Rispoli and V. Rayz, advisors). Everyone is invited to attend the public presentation beginning at 2:00 PM in MJIS 2001. Research title: Conductive fabric based wearable coil for cervical spine and carotid arteries MRI at 3T. Thesis committee members: Dr. Joseph Rispoli (co-chair), Dr. Vitaliy Rayz (co-chair), Dr. Craig Goergen (committee member) and Dr. Uzay Emir (committee member). Abstract: MRI is a non-ionizing, non-invasive imaging modality that provides superior soft tissue contrast. Radiofrequency (RF) coils are the antennas through which images are obtained in MRI. Volume coils provide a homogeneous field around the region of interest (ROI) while surface coils help obtain the maximum signal-to-noise ratio (SNR) for high resolution images. Receive arrays are made of multiple surface coils for concomitant acquisition of spatial information from the anatomy, thus enabling parallel imaging. MR angiography (MRA) techniques such as time-of-flight (TOF) MRI and phase contrast (PC) angiography take advantage of parallel imaging to visualize the vasculature and understand the underlying hemodynamics that can lead to cardiovascular diseases, especially in the carotid arteries. A rigid whole neck array that contains coils that extend to the cervical spine are often used to image the carotid arteries. However, the rigid neck array lacks adaptability to varying neck sizes, thus limiting the SNR. Wearable coils that tightly conform around the anatomy of interest developed using techniques such as screen printing, conductive elastomer, and conductive thread reduce coil setup time while ensuring maximum SNR in the final image. However, current wearable coil fabrication methods require specialized manufacturing practices, which render coil development an expensive process. Therefore, a wearable array developed using commercially available conductive fabric is proposed for simultaneous bilateral carotid arteries and cervical spine imaging at 3T. The conductive fabric method eliminates specialized manufacturing needs for developing wearable coils, thus enhancing RF coil accessibility without compromising patient comfort and image quality. Zoom link: https://purdue-edu.zoom.us/j/92041421380?pwd=SGRQaVcvS3MrdEduSHdIazBSNFVkZz09<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-edu.zoom.us%2Fj%2F92041421380%3Fpwd%3DSGRQaVcvS3MrdEduSHdIazBSNFVkZz09&data=05%7C02%7Cbmeroundtable-list%40ecn.purdue.edu%7C529609247f2141fdb9db08dc68572147%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638499970668870273%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=LQXUsi7pJKfd0pe5NGXMQDnGQl7dPUaPkIhc1pJRkRQ%3D&reserved=0> Thurs., May 2: BME Master's Defense Announcement for Adalyn Meeks (Craig Goergen, advisor). Everyone is invited to attend the public presentation beginning at 2:00 PM EST in MJIS 2001 and via Zoom. Title: High-Frequency Murine Ultrasound of Microrobot Drug Delivery Systems and Cardiac Effects of Hypertension During Pregnancy. Committee: Dr. Craig Goergen (Chair), Dr. David Cappelleri, Dr. Luis Solorio Abstract: Murine, or small rodent, models can provide valuable and translatable insights into human pathophysiology. Specifically, we are looking to combine murine models and high-frequency ultrasound to non-invasively investigate microrobot drug delivery systems and cardiac remodeling due to the combination of pregnancy and hypertension. Currently, we are looking at the applications of microrobots within the colon to provide targeted treatment for patients suffering with inflammatory bowel disease (IBD). IBD is an overarching term encompassing chronic inflammation of the digestive tract tissue. The standard treatment of IBD includes oral and injectable treatments depending on disease severity. The drawbacks of these therapeutics are the associated systemic toxicity, non-specific treatment allocation, and degradation of the treatment in proximal portions of the gastrointestinal (GI) system. The goal of this research is to use an external magnetic torque to cause the microrobots to tumble to targeted areas of inflammation and release a drug payload. Retroactive locomotion of these microrobots can avoid degradation in the proximal GI tract. Therefore, these microrobots need a smaller drug payload to provide the same efficacy as traditional treatments. Chronic hypertension affects approximately 1 in 20 pregnancies and its prevalence in pregnancies continues to increase. The maternal cardiovascular system goes through dynamic changes during pregnancy to meet the demands of perfusing the gestation, especially during the exponential growth seen later in pregnancy. Studies with female C57BL/6J mice demonstrate comparable cardiovascular changes during pregnancy to those observed in humans. Additionally, a study using rats showed the cardioprotective properties of pregnancy against angiotensin II induced fibrosis. The objective of this study is to characterize non-invasive cardiac remodeling in a small animal model of hypertensive disorders in pregnancy. We used a combination of ultrasound imaging and noninvasive blood pressure measurements to longitudinally monitor the physiological adaptations that occur during pregnancy with superimposed hypertension. Zoom link: https://purdue.edu.zoom.us/j/97871973409?pwd=ZndVVmJ6Z3JUM0FuNU40aFF6elA4QT09<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.edu.zoom.us%2Fj%2F97871973409%3Fpwd%3DZndVVmJ6Z3JUM0FuNU40aFF6elA4QT09&data=05%7C02%7Cbmeroundtable-list%40ecn.purdue.edu%7C529609247f2141fdb9db08dc68572147%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638499970668870273%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=qMra4MrjNb8S0aA8nR9JaZo5NW67zvZXO4DYbfBUq20%3D&reserved=0> Meeting ID: 978 7197 3409 Passcode: 091537 Tues., May 7: BME PhD Defense Announcement for Vidhya Vijayakrishnan Nair (Yunjie Tong, advisor). Everyone is invited to attend the public presentation beginning at 9:00 AM in MJIS 2001 and via Zoom. Research title: Human Cerebrospinal Fluid Movement across Wake and Sleep States - A Multimodal Imaging Study. Thesis Committee Members: Dr. Yunjie Tong (Chair), Dr. A.J. Schwichtenberg, Dr. Vitaliy L. Rayz, Dr. Yu-Chien Wu. Abstract: The movement of Cerebrospinal Fluid (CSF) within the brain's ventricles and the subarachnoid spaces of both the cranium and spine is crucial for the health and functioning of the central nervous system. Recent research has emphasized CSF movement's importance in metabolic waste clearance and its effect on the pathophysiology of neurodegenerative and neurodevelopmental disorders. Additionally, CSF movement is significantly enhanced during Non-rapid eye movement (NREM) sleep. Despite the critical role of CSF in maintaining brain health, a comprehensive understanding of the mechanisms driving its movement across different states of wakefulness and sleep is lacking. In this work, multimodal imaging was utilized to simultaneously monitor CSF movement and brain hemodynamics via functional Magnetic Resonance Imaging (MRI), neural activity through Electroencephalography (EEG), and non-neuronal systemic physiology via peripheral functional Near-Infrared Spectroscopy (fNIRS). Our findings reveal that CSF movement is influenced by multiple physiological forces concurrently. During wakefulness, both low-frequency vasomotion and respiration interact to regulate CSF movement. Furthermore, systemic physiological changes significantly impact CSF movement during light NREM sleep, even in the presence of autonomic neural activity. Notably, during deep NREM3 sleep, CSF movement magnitude increases independent of the magnitude of brain hemodynamics, suggesting a decrease in impedance to CSF movement and an enhanced exchange between CSF and interstitial fluid (ISF) in the brain. Building on these observations, significant enhancement of CSF movement was also achieved via simple respiratory interventions, thereby demonstrating their potential to be used as clinical protocols across pathologies characterized by reduced CSF movement. Zoom Meeting Link: https://purdue-edu.zoom.us/j/95341354792?pwd=L2ZBTmJYUEVDRXhDTm03cU9JYlBOUT09<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-edu.zoom.us%2Fj%2F95341354792%3Fpwd%3DL2ZBTmJYUEVDRXhDTm03cU9JYlBOUT09&data=05%7C02%7Cbmeroundtable-list%40ecn.purdue.edu%7C529609247f2141fdb9db08dc68572147%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638499970668870273%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=8fRQ7sks2Vglh%2Beh3N2yFMOS0OAA4vwp8gF4dDaMXIU%3D&reserved=0> Meeting ID: 953 4135 4792 Passcode: 741481 Wed., May 8: BME PhD Defense Announcement for Yilun Li (Fang Huang, advisor). Everyone is invited to attend the public presentation beginning at 10:00AM EST in FLEX B038 or via Zoom. Title: A user-centric cloud computation platform for super-resolution imaging reconstruction. Committee Members: FANG HUANG (Chair), DANIEL M. SUTER, STEVEN T. WERELEY, XIAOHUI C. SONG Abstract: Single-molecule localization microscopy (SMLM) leverages the detection and localization of individual fluorescently tagged molecules to visualize cellular and tissue samples at a nanometer resolution. The reconstruction of a super-resolution image via SMLM, however, involves intricate algorithms and large scale computation that may require hours to achieve a single high-quality 3D image. Additionally, the image generation process calls for specialized expertise and resources, such as knowledge of image processing and massively parallel computing. To address these challenges, we are developing an integrated cloud-based SMLM suite named "cloud-SMLM". This suite combines key algorithms from each stage of single molecule analysis, integrating with high levels of parallelization. Deployable on cloud-based computational services like Amazon Web Service (AWS), cloud-SMLM interacts with its users through a dedicated, easy-to-use drag-and-drop webpage. This design eliminates the prerequisite for hardware such as GPU and reduces the knowledge barrier for users of single molecule nanoscopy. Accessible from any web-browser equipped device, it enables users to initiate and modify data reconstruction. Furthermore, it provides visualization and data mining tools for users to explore the reconstructed three-dimensional ultra-high-resolution cellular and tissue volumes. We expect that this project will democratize existing and new single molecule super-resolution imaging capacities by integrating them into computational pipelines for a wide range of biological model systems. We believe that the success of cloud-SMLM will represent a significant step towards unlocking the full potential of ultra-high resolution optical imaging in biological and biomedical research. Join Zoom Meeting https://purdue-edu.zoom.us/j/91595672410?pwd=c2lyTzVSTXpuTTA1R3o2aWR4Y1l2UT09<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-edu.zoom.us%2Fj%2F91595672410%3Fpwd%3Dc2lyTzVSTXpuTTA1R3o2aWR4Y1l2UT09&data=05%7C02%7Cbmeroundtable-list%40ecn.purdue.edu%7C529609247f2141fdb9db08dc68572147%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638499970668870273%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=HTLdH9SLv45uRbZQ3Cn99u1uVS5rnifrFZxSh4J2U3w%3D&reserved=0> Meeting ID: 915 9567 2410 Passcode: 730694 Thurs., May 23-Fri., May 24: 2024 Hitchhiker's Guide to the Biomolecular Galaxy, Armstrong Hall. Registration is officially open for the 2024 Hitchhiker's Guide to the Biomolecular Galaxy! Please register using this link<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fqualtricsxmmx7jkjmbp.qualtrics.com%2Fjfe%2Fform%2FSV_7aoqAK53GeyeKMu&data=05%7C02%7Cbmeroundtable-list%40ecn.purdue.edu%7C529609247f2141fdb9db08dc68572147%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638499970668870273%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=Yeel8PMCKG%2B9XGTU%2BU6VG6hcaVKut0wbY1OxZTvT6hc%3D&reserved=0>. Hitchhiker's Guide to the Biomolecular Galaxy Symposium brings together undergraduate students, graduate students, post-doctorates, and faculty throughout the Midwest who are all striving to share and gain more insight into various biophysical approaches. Registration is completely free with breakfast, lunch, coffee, and snacks provided both days. The symposium will include a keynote address given by Dr. Jin Zhang from the University of California San Diego. Dr. Zhang's research lab developed a series of molecular tools and fluorescence imaging technologies to understand the spatiotemporal regulation of cell signaling. <https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fjinzhanglab.ucsd.edu%2F&data=05%7C02%7Cbmeroundtable-list%40ecn.purdue.edu%7C529609247f2141fdb9db08dc68572147%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638499970669026550%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=byAAyrijkwwecL5SQ2fJkSymCOiiwqH73U5afVu0DXE%3D&reserved=0> We will be hosting pre-symposium events on Wednesday, May 22nd 2024. Our pre-symposium events are focused on advancing careers with professional development and implementing diversity and inclusion in our field, along with social and networking opportunities with other researchers at Purdue and the Midwest! Each day of the symposium will consist of seminar style lectures where graduate students, postdoctoral fellows, undergraduates, faculty, and visitors can share their work. If you would like to present an oral presentation, please submit an abstract when registering by May 10, 2024. The first day will also include a two-hour workshop session with four technical workshops: * Easy (and accurate) structure modeling & validation on web server for cryo-EM * An introduction to 3D Molecular movies (PyMOL, Chimera, Blender/Maya) * Figure Making and Ethics * Quantitative proteomics When registering for the symposium, participants will rank the order of workshops they are interested in (1 being the most likely). Participants will be placed in each workshop on a first-come, first- serve basis upon registering until the workshop reaches maximum capacity. On the second day of the symposium, we will be hosting a two-hour poster session. If you would like to participate in this poster session, please submit an abstract by May 10, 2024, when registering for the symposium! Awards will be given to the Top 3 posters and oral presentations, with a People's Choice award at the end of the second day. Hope to see you all there! On behalf of the 2024 organizing committee: Co-Chair, Kadidia Samassekou (Department of Chemistry) Co-Chair, Vaani Ohri (Department of Biological Sciences) Kadir Ozcan (Department of Biological Sciences) Hanna Bovill (Department of Chemistry) Ketaki Mahurkar (PULSe/Department of Chemistry) Michelle Bush (Department of Biological Sciences) Ryan Peters (Department of Biological Sciences) Hunain Janjua (PULSe/Department of Biological Sciences) Faculty Mentor: Dr. Lauren Ann Metskas (Department of Biological Sciences and Chemistry) Postdoctoral Fellow Opportunity - IUSM Emergency Medicine The laboratory of Dr. Nathan J. Alves, PhD, within the Department of Emergency Medicine at the Indiana University School of Medicine (IUSM), is seeking a highly motivated and independent post-doctoral research fellow. Dr. Alves is a Chemical and Biomolecular Engineer, Associate Professor and the Director of Translational Research for the Department of Emergency Medicine in addition to having an affiliate faculty appointment at Purdue University in Biomedical Engineering. The Alves Lab explores highly interdisciplinary research interests applying engineering and biophysical principles and designs to create translational technologies and treatments in the area of blood coagulation and fibrinolysis. The primary focus of research in the laboratory is to develop targeted clot digesting therapeutic agents to more safely digest clinically relevant blood clots to treat pulmonary embolism (PE, blood clots in the lungs), deep vein thrombosis (DVT), and ischemic stroke. This interdisciplinary research utilizes diverse enzyme assays, chemical synthesis, blood clot formation and digestion assays under shear, and other novel testing/delivery platforms that include multivalent branched molecules and nanoparticle drug delivery systems. Projects Include: (1) Leveraging multivalency to modulate enzyme activity and improve inhibitor selectivity (nanoparticle drug delivery and targeting). (2) Ex-vivo flowing models of clot digestion under shear using in-vivo like fluorescently labeled blood clots from human whole blood. (3) Development of novel fibrinolytic diagnostics tools to assess coagulation state. (4) Mouse models of clot formation/targeting/digestion utilizing intravital microscopy. (5) Study the effects of environmental microplastic exposure on coagulation/fibrinolysis. Projects are funded both externally and internally. For additional information and to apply, go to: https://indiana.peopleadmin.com/postings/19651<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Findiana.peopleadmin.com%2Fpostings%2F19651&data=05%7C02%7Cbmeroundtable-list%40ecn.purdue.edu%7C529609247f2141fdb9db08dc68572147%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638499970669026550%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C0%7C%7C%7C&sdata=ql3v1eqGCEJb6lqCQXbf1VJ0lXwBe5ASLR%2By%2FS9Dv4A%3D&reserved=0> -- Bmeroundtable-list mailing list Bmeroundtable-list@ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list