[cid:image003.png@01D90E13.F1E0F680] BME MONDAY ROUNDTABLE December 12, 2022 HEADS NOTE As the semester winds down and we gear up for 2023 I want to thank everyone in the school for making 2022 such a tremendous year for the Weldon School. I’ve greatly enjoyed meeting many new students in the school, and welcoming new faculty and staff. I’m grateful for the opportunities I had in 2022 to interact with you and support your professional and academic development. This upcoming Thursday, be sure to visit the BME Senior Design Expo to witness all the creative engineering conducted by our Seniors and celebrate their achievements! UPCOMING IMPORTANT DATES Week of December 12 Mon., Dec. 12: BME PhD Preliminary Exam Announcement for Li Fang (F. Huang, advisor), 2:30 p.m., MJIS 2001 and via Zoom. Title: Molecular localization of single molecule switching sequences with deep learning. Thurs., Dec. 15 The BME Senior Design Expo will be from 3:30 - 5:30pm in MJIS 1097, 1001, and Atrium. There will be 24 projects presented followed by awards ceremony. Stay tuned for additional details. Holiday Updates Purdue University will be closed beginning Friday, December 23rd and will reopen on Tuesday, January 3rd. This means all offices, labs and buildings will be closed. This translates to no mail or package delivery, so (hopefully) you haven’t ordered anything perishable that will languish until your return on Tuesday, January 3rd.. We will also be closing and locking the student club room (MJIS 1051) over this time. Any food left in the refrigerator as of 5:00 p.m. on Thursday, December 22nd will be put in the trash. REMINDER: users of the Club Room on the 1st floor ARE RESPONSIBLE FOR CLEANING UP YOUR OWN MESSES. Lately, there has been an exponential increase in splattered food not being wiped out of the microwave, and other food debris left on the table surfaces, which has led to an influx of mice (and mice droppings) in this room. If you use the club room, YOU are responsible for cleaning up your mess. We don’t want to be forced to shut this area down, but if it continues to be left dirty, with unlabeled food in the refrigerator, we may have to take more drastic measures for everyone’s health safety. Researchers also need to make note that for the Winter Recess – The ordering deadline for research materials (animals, chemicals, drugs, etc.) will be noon on Wednesday, December 14, 2022, for delivery dates of December 19 – 22, 2022. There will be no deliveries of any kind on campus from December 22, 2022 through January 3, 2023. This same schedule will be followed for Drug Distribution Center orders. Please plan accordingly. Upcoming important deadlines and info. Fri., Dec. 23 through Mon., Jan. 2: Winter Recess. No classes, all university offices and buildings closed. Purdue will reopen Tuesday, January 3. Mon., Jan. 9: Deadline to submit Summer Undergraduate Research Fellowship (SURF) project proposal. The Summer Undergraduate Research Fellowship (SURF) program is now accepting project proposals from faculty for the 2023 program. Purdue faculty may post a research project on the EURO website<https://engineering.purdue.edu/Engr/Research/EURO/info-faculty> now through Jan. 9 and select a student from the pool of applicants between Jan. 9 and Feb. 15 when the student application portal opens. Final selections should be made no later than March 1. SURF is an opportunity for undergraduates to gain research experience under the guidance of a Purdue professor. The program is open to students enrolled at U.S. institutions in a baccalaureate degree program. For more information, contact John Howarter, Engineering Undergraduate Research Office (EURO) director and associate professor of materials engineering and environmental and ecological engineering, at howarter@purdue.edu<mailto:howarter@purdue.edu>. PURDUE ADVERSE WINTER WEATHER POLICY If adverse weather conditions necessitate that a wind chill, snow or ice emergency be declared for the West Lafayette campus, special procedures pertaining to classes, operations, parking, pay and/or attendance will become effective. Jay Wasson, vice president for physical facilities and chief public safety officer, describes procedures for adverse winter weather in this memo<https://www.purdue.edu/ehps/emergency-preparedness/docs/adverse-winter-weather.pdf>. Committee Updates IUPUI-Purdue Integration Update As you have seen in the Provost updates, the IUPUI-Purdue integration continues to gain momentum. We were happy that our work in BME is being highlighted. Central to all discussions and planning are our core values of respect, belonging, and excellence. Our particular focus in academic programs is providing a rigorous and inclusive training environment for our students; with a culture of respect and belonging such that each student attains their highest potential of excellence. The joint IUPUI-Purdue team share these values and a strong collaborative spirit that led to many positive and productive discussions thus far. The Weldon School meet with IUPUI BME colleagues for a day-long workshop on Nov 4.day.Undergraduate programs integration team focused on programmatic learning outcomes and identifying similarities and differences among the two curriculum. The graduate programs team also focused at the programmatic level on which degrees to offer on the two campuses and on impact on students already in the IUPUI programs. Attached are the notes from the meeting with many, many more details. The UG and Grad integration teams are continuing to meet at least every other week as we work toward a detailed teach-out plan that is due on Jan 31. Academic Programs Update Please make note of the grading deadline for all research students (grad & undergrad) and your Fall classes: Grade entry began at 8 a.m. December 2 and ends at 5 p.m. December 20. Faculty at West Lafayette not meeting the submission deadline for their reporting window will be required to submit via the Grade change workflow found in their myPurdue portal. Undergraduate Programs Update The BME Senior Design Expo will be Thursday, December 15 from 3:30 - 5:30pm in MJIS 1097, 1001 and Atrium. There will be 24 projects presented followed by awards ceremony. Stay tuned for additional details. Graduate Office Update It is officially Three Minute Thesis (3MT®) competition season! To increase academic representation in our 3MT® competition, we are asking that West Lafayette graduate faculty members nominate talented graduate student(s) to represent their academic units. This is an exciting year to participate, as we have increased the cash prizes, which include $5,000 for first place, $3,000 for second place, and $2,000 for the People’s Choice Award winner. Nominees must be current Purdue graduate students studying at the West Lafayette campus. Each nominee will be contacted by Graduate School staff and encouraged to register for the competition. Nominations are not required for students to submit a draft video; they are simply intended to help the Graduate School identify and encouraged talented students to participate. The link to the nomination form below, as well as some additional information about the Graduate School’s 3MT® competition. Please email me, Allison Loy (Loy2@purdue.edu<mailto:Loy2@purdue.edu>), with any questions! Virtual 3MT® 2023 Nomination Form: * Nomination Deadline: January 13, 2023 https://purdue.ca1.qualtrics.com/jfe/form/SV_204r4KOtt2fUIbI What is 3MT®? Three Minute Thesis (3MT®) is a research communication competition that helps graduate students develop academic, presentation, and research communication skills so that they can effectively explain their research to a non-specialist audience. During each competition, graduate students will have three minutes to present a compelling discussion on their research topic, including its significance and relevance, to the general public. This is a fast-paced competition where the top 10 finalists compete by summarizing their two to three-plus years of research in only three minutes with only one slide. The cash awards for this year’s competition have been increased substantially, including $5,000 for first place, $3,000 for second place, and $2,000 for the People’s Choice Award winner. The first-place winner will also be invited to compete in the Midwestern Association of Graduate School’s (MAGS) annual 3MT® competition. 3MT® Timeline * Friday, February 10: Draft Video Submission Deadline – Learn more about making a draft video!<https://www.purdue.edu/gradschool/professional-development/documents/Virtual_3MT_Competitors_Guide.pdf> * Friday, February 24: Semifinalists Announced * Friday, March 3: Semi-Finals * Monday, March 6: Finalists Announced * Monday, April 10: 3MT® Rehearsal * Tuesday, April 11: 3MT® Competition Learn more about the Purdue University Graduate School’s 3MT® competition here: https://www.purdue.edu/gradschool/professional-development/competitions/3mt/... Graduate Admissions Update Fall 2022 (Fall 2023 Admit Term) BME Graduate Admissions DateDATE Activity Now Research Areas create a plan and potentially agree on dates to meet ranking deadlines. December 19th—All Fellowship Nominations Due Dec 19 DUE: All Fellowship Nominations and Additional Invite Lists Dec 20 Grad office to process admission for all fellowship-nominated applicants to the Purdue Graduate School and any additional applicants you would like to admit from the open house invitation list. Dec 20 Tammy to send invitations to invited students to participate in our virtual open house. Jan 3 Deadline for students to respond to Open House RSVP (hotels released today). Jan 26 Agendas for all invited students due from faculty to Tammy and sent to student. Feb 2-4 Weldon School Visitation Days (Hybrid) Feb 8 Last chance for Research Areas / Faculty to remove students from fellowship consideration Feb 10 Fellowship offers announced and complete rankings list made available to BME faculty; BME Graduate Office will notify students by email (offer letters distributed as soon as signed by BME Head and COE Dean) Mar 10 DUE: All Master’s students to be decisioned as either admit, deny or hold Mar 31 Due: All PhD students to be decisioned as either admit, deny or hold April 15 Graduate applicant acceptance deadline Resources, attachments, further information BME PhD Preliminary Exam Announcement for Li Fang (F. Huang, advisor), Mon., Dec. 12, 2:30 p.m., MJIS 2001 and via Zoom. Title: Molecular localization of single molecule switching sequences with deep learning. Committee members: Dr. Fang Huang, Chair; Dr. Leopold N. Green; Dr. ‪Young L. Kim; Dr. Chongli Yuan Abstract: Single molecule localization microscopy (SMLM) has become an essential tool in imaging nanoscale biological structures. It breaks the diffraction limit by utilizing photo-switchable or photo-convertible fluorophores to obtain isolated single molecule emission patterns (i.e. PSFs) and subsequently localize the molecule’s position with a precision down to ~ 25 to 80 nm laterally-axially. However, standard SMLM algorithms require sparse activation to minimize emission pattern overlapping, which limits imaging speed and temporal resolution and hinders its application in dynamic live cell imaging. Some multi-emitter fitting algorithms have been developed to analyze higher density data and some methods have shown improved localization precision when utilizing multiple frames. But these methods require an accurate PSF model and prior knowledge of photo-switching behavior and fail to fully extract the information in the sequence data. Here, we propose to develop a high-density single molecule localization algorithm through molecule blinking sequence analysis with deep learning to achieve high localization precision approaching the theoretical limit at high density in three dimensions. We aim to apply the algorithm to resolve nanoscale intracellular structures and fast dynamic processes in live cells with high temporal and spatial resolution. Virtual link: https://purdue-edu.zoom.us/j/99210793060?pwd=WnlHbVlSUlNGWE1KaGN4QWRCS0lEUT0... Meeting ID: 992 1079 3060 Passcode: 158594 Attachments Nov 4 Academic Programs Integration Workshop – meeting notes_Final -- Bmeroundtable-list mailing list Bmeroundtable-list@ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list