[cid:image001.jpg@01DA1160.FDBF0D60] BME WEEKLY ROUNDTABLE WEEK OF November 6, 2023 INTERIM HEAD'S NOTE * In the faculty meeting last Friday, we had fewer updates but more discussions, which is what I intended to do. We talked about how to proceed with the partnership development with Ascension Health, who came to visit us last Tuesday, and how to advance partnership development in general. It is important that we have the right mindset when approaching such partnership opportunities. I also talked about my plan for the last faculty meeting of this semester and the ones next semester. In the last faculty meeting of the semester, we would like to take a moment to look at the status of our academic programs, especially PMP and online programs. I'd also like to go over our teaching assignment model. Note that this is more an information review meeting. More discussions shall follow next semester. Your comments are welcome. * One person has been made an offer for the department Marketing and Communications specialist position. She has tentatively accepted the offer and is excited to be on board. We have started the drafting of the offer letter. I want to highlight tomorrow's seminar here. Dr. Mobasser was part of the Ascension Health delegation and participated in the workshop last Tuesday online. For more information, please scroll down this email, in the Upcoming Important Dates section. UPCOMING IMPORTANT DATES Week of November 6 Sun., Nov. 5: HOPE YOU REMEMBERED TO CHANGE YOUR CLOCKS! Eastern Daylight time ended on Sunday, November 5th, at 2:00 a.m. "Spring ahead, fall behind..." Mon., Nov. 6: Midwest Mechanics Seminar 2023, 3:30 p.m., ARMS B071. Dr. Alison Marsden, Douglass M. and Nola Leishman Professor of Cardiovascular Disease, Professor of Pediatrics and Bioengineering, and by courtesy of Mechanical Engineering, Institute for Computational and Mathematical Engineering, Stanford University, will present "Multi-physics Modeling of Flow and Cardiac Function in Pediatric Cardiology." Tues., Nov. 7: EEE Research Seminar, 10:30 a.m., POTR 234 (Fu Room). Dr. Krystel Castillo, Lutcher Brown Chair of Mechanical Engineering, Vice President for Energy Efficiency at the Cybersecurity Manufacturing Innovation Institute, and Director of the Texas Sustainable Energy Research Institute at The University of Texas at San Antonio will present "Integrated Data Analytics Scheme to Enable Energy Efficient Secure Manufacturing and Energy Systems." This seminar is sponsored by Purdue's Department of Environmental and Ecological Engineering. Wed., Nov. 8: Weldon School of BME Research Seminar, 9:30 a.m., MJIS 1001 and via Zoom. Jean-Pierre Mobasser, MD, President, Goodman Campbell Brain and Spine will present "Advancements in Minimally Invasive Lumbar Fusion: A Comparative Review." Wed., Nov. 8, Advancing Discovery in Antimicrobial Resistance Seminar Series, 12:00 noon, Purdue DRUG, Lobby Conference Room. Dr. G. Kenitra Hendrix, Director of the Animal Disease Diagnostic Laboratory, Section Head, Bacteriology, Mycology, and Parasitology Laboratories, Clinical Associate Professor of Veterinary Diagnostic Microbiology, Department of Comparative Pathobiology and ADDL at Purdue will present "The Role of Veterinary Diagnostic Laboratories in National AMR Surveillance Programs." The seminars are sponsored by the College of Veterinary Medicine, Department of Basic Medical Sciences. Wed., Nov. 8: Diabetes Research Virtual Seminar Series, 2:00 p.m., via Zoom. Arleen F. Brown, MD, PhD, Prfoessor of Medicine, General Internal Medicine and Health Services Research and Co-Director, UCLA Clinical & Translational Science Institute and Community Engagement & Research Program will discuss "Structural Interventions to Address Cardiometabolic Disease Disparities." Thurs., Nov. 9: BME PhD Preliminary Exam for Grigorii Rudakov (T. Kinzer-Ursem and L. Green, co-advisors). Everyone is invited to attend the public presentation beginning at 9:00 am in MJIS 2001. For coffee and bagels come 15 minutes early. Title: DNA Tetrahedron Design Optimization for Efficient Drug Delivery Through the Blood-Brain Barrier. Thurs., Nov. 9: Seminars in Hearing Research, 12:00 noon, Nelson Hall, Room 1215. Samantha Hauser and Andrew Sivaprakasam will present "Audiology Research Diagnostics Core (ARDC) & Data Repository: Big Data Analysis for Hearing Research." MJIS ALERT As of Wed., Nov. 29: Telephone System Update Implemented, 7:00 p.m. Purdue IT is completing the long-running project to retire the phone switch installed more than 25 years ago. Beginning after 7:00 p.m. EST, November 29, changes to the way you use the Purdue West Lafayette telephone systems will be required, including required use of area codes for ALL calls. See link below for details. ACADEMIC PROGRAMS ALERT Re: final exam accommodations. We have a number of students who may need accommodations for final exams and faculty need to be proactive in scheduling with the Testing Center if they plan to use that. Below is some important information instructors should know if they choose to have Purdue Testing Services (PTS) administer their accommodated exams. * The steps to submit a Testing Instruction Form (TIF) for finals week are the same as any other exam with one notable difference. In the "select the exam group/s for this test" field, be sure to select your course that starts with Accommodated FINAL Exam. This is required before students will be able to schedule during finals week. *If you had already submitted a TIF for your final prior to receiving this email, PTS staff updated your TIF to the correct exam group * Hours of operation: * Monday - Friday | 8 a.m. - 10 p.m. * Exam start times: 8 a.m., 10:30 a.m., 1 p.m., 3:30 p.m., 6 p.m. and 7 p.m. * Saturday | 8 a.m. - 4:30 p.m. * Exam start times: 8 a.m., 10:30 a.m., Noon and 1 p.m. * Due to the volume of exams we administer, we will not start any exam outside of the start times mentioned above. Please take this into consideration if you are adding time restrictions to your TIF. * The deadline for students to schedule their final exams with PTS is Dec. 1, 2023. Students who miss the deadline will be redirected to their instructors to discuss alternate arrangements to still receive their accommodations. * There may be times when PTS reaches full capacity prior to the scheduling deadline. If this occurs, instructors will either be asked to select a different day/start time in which PTS has seats available or they will need to make alternate arrangements to provide the accommodations. Another email will be sent closer to finals week with more important information regarding delivery and return methods. Instructors may find up-to-date information as well as step-by-step guides on our website<https://maillinks.purdue.edu/t/45449744/1695007246/97441342/0/1003726/?x=2c5e62c2>. Thanks, Kelsey Jordan, M.S. she/her/hers Director, Purdue Testing Services ALSO: We are now more than halfway through the Fall term so here are some reminders as we round the corner to final grading: * This is the perfect time to ensure that your web certifications are current so you don't get stuck during a deadline. FERPA, GLBA, Protecting SSNs, and Data Handling all must be current at the time of grade entry to prevent any roadblocks. * Final grading window https://www.purdue.edu/registrar/faculty/grading/index.html Full Term (16 Weeks) and Second Eight-Week Session (meeting between October 18 and December 16) Grade entry begins at 8 a.m. December 1 and ends at 5 p.m. December 19. GRADUATE PROGRAM UPDATE Fellowship Opportunity The Bilsland Dissertation Fellowship provides support for outstanding PhD candidates in their final year or semester of doctoral degree completion. The goal of the fellowship is to allow exceptional candidates to focus exclusively on finishing their dissertation. The Graduate School Fellowship Manual has additional details https://www.purdue.edu/gradschool/fellowship/fellowship-resources-for-staff/... Note: Students in other schools outside of BME should follow those schools' procedures. Due Date: Sunday, December 3rd (tsiemers@purdue.edu<mailto:tsiemers@purdue.edu>) Student Eligibility * At the time of nomination, students must have 1) completed their preliminary exam or, 2) submitted the paperwork scheduling their preliminary exam for a date before May 31. * Students who will complete their defense prior to September 1, 2024, are not eligible. * Students who need less than 1 semester of support are not eligible. * Nominees must be outstanding engineering PhD students. * The following criteria will be used to rank the nominees: * Merit. Includes publications, conference presentations, GPA etc. * Funding need. * Good citizen of the School and College. Includes service. * Career promise. Includes leadership, innovation, readiness and potential to make an impact. Application Package Should Include the following in one PDF: * A letter (limit 2 pages) from the major professor nominating the student and confirming that the student's expected graduation date. This can be sent separately if the student is providing the rest of the information. * The student's thesis abstract, * A copy of the preliminary examination paperwork (to confirm the student is on track to graduate next year), * The student's CV, * A copy of the student's most recent transcript - graduate work only. Salary & Usage: * This fellowship includes $30,000 annual salary, tuition remission, medical insurance premium contribution, and coverage of most fees. Engineering differential fee is not covered. * Bilsland Fellowships are administered as assistantships. It is expected that job duties will contribute to the completion of the student's dissertation. * Bilsland's must be awarded in the student's last term, and the student is expected to graduate at the end of the fellowship term. * This year's Bilsland allocation may be used Summer 2024, Fall 2024, Spring 2025, or Summer 2025. * No additional work appointments may be added, but faculty may (and perhaps must; depending on our minimum salary requirement which may be set in BME) increase the salary or provide additional funds as scholarships. * The fellowship is to be awarded for the full 12 months or until the student graduates, whichever comes first. * Fellowship recipients who graduate before the completion of the fellowship or otherwise stop the fellowship before the full 12 month duration forfeit any remaining funds. * If Bilsland Fellows do not graduate as expected this could hurt our funding allocation from the Graduate School, so please only nominate students you truly expect to graduate and are truly in their final year. The announcement will go out to the students as well. Please let me know if you have any questions. Excellence in Teaching Awards Competition Applications are now being accepted for the Midwestern Association of Graduate Schools (MAGS) 2024 Excellence in Teaching Awards Competition. The University is eligible to nominate one masters-level and one Ph.D.-level student for each award that includes a citation and a $750 honorarium that will be presented at the MAGS annual meeting on April 3-5, 2024. Interested students must submit their application materials to the Graduate School by Friday, December 1, 2023, at 5:00 p.m. for consideration. Award Details * The 2024 Excellence in Teaching Awards will be bestowed on "...graduate students who exemplify excellence in the teaching and learning mission of our universities.... [to] recognize the importance of excellence in teaching and mentoring as a component of graduate education and the preparation of graduate students for future service as college and university faculty." * Details of the Award, as well as a list of previous recipients, are available here: https://mags-net.org/excellence-in-teaching-award/<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmags-net.org%2Fexcellence-in-teaching-award%2F&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659289845447%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=A8DZSCEAmMZCHC8xjyo6q3jyg5G41wbXVYUULKXvDt0%3D&reserved=0> * The Dean of the Graduate School/College (or designee) at each MAGS-affiliated university may select and submit the materials of one doctoral and one masters-level graduate student for these awards. * MAGS's evaluation criteria are shared here: https://mags-net.org/wp-content/uploads/2023/10/2024_MAGS_Exc_Teach_Award_Eval_Criteria.pdf<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmags-net.org%2Fwp-content%2Fuploads%2F2023%2F10%2F2024_MAGS_Exc_Teach_Award_Eval_Criteria.pdf&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290001720%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=nL7ib7D4kl7d%2BTHtechtj2tkVznp6rD1OzzXgmVQIWw%3D&reserved=0> Submission Details Graduate students wishing to be considered for this award must submit a single PDF document that includes: * a letter of nomination from the student's department head * the nominee's teaching portfolio * up to six (6) pages, double-spaced, 1-inch margins, with a 12-point font * an embedded link to a video (maximum of 10 minutes) showing the nominee teaching in an educational setting of a collegiate-level course * for instructions on saving and submitting a suitable video, please see: https://mags-net.org/wp-content/uploads/2023/10/2024_MAGS_Exc_Teach_Award_You_Tube_Instr.pdf<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmags-net.org%2Fwp-content%2Fuploads%2F2023%2F10%2F2024_MAGS_Exc_Teach_Award_You_Tube_Instr.pdf&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290001720%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=ISdQu%2B2e05qdIS1IdWqzjJ9eaUSQtyGnVifX%2BdjAIVg%3D&reserved=0> * all individuals who are identifiable in the video and over the age of 18 should complete a consent and release form, and the portfolio description of the video should indicate that these have been collected. The Use of Photographic and Vido/Film Consent and Release Form can be completed (and will be stored) online via Qualtrics here: * https://purdue.ca1.qualtrics.com/jfe/form/SV_8AZILsZOZwtg96u<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca1.qualtrics.com%2Fjfe%2Fform%2FSV_8AZILsZOZwtg96u&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290001720%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=OWGPIY86exiPChPexOGYNfoPbbLBb0PX%2F39yU%2FtQmz8%3D&reserved=0> * the student's current curriculum vitae * Since Purdue must review and select nominees' materials to be sent along to MAGS, materials should be submitted by Friday, December 1, 2023, at 5:00 p.m. to * MAGS_Ex.oewymn7ybxjoxsm0@u.box.com<mailto:MAGS_Ex.oewymn7ybxjoxsm0@u.box.com> Timeline toward nomination * Purdue deadline for submissions: Friday, December 1, 2023 * Review of campus nominees: December 4-11, 2023 * Notification of campus nominees: December 15, 2023 * Completion of nomination packets (including an endorsement from the Associate Provost for Graduate Programs) and submission to MAGS: January 5, 2024 Questions? Please contact Associate Dean David Rollock at the Graduate School (rollock@purdue.edu<mailto:rollock@purdue.edu>; 496-2775). Upcoming important deadlines and information Mon., Nov. 13: Center for Diabetes and Metabolic Diseases Research Seminar Series/Diabetes Day, 12:00 p.m., R4-101 (Indianapolis) and via Zoom. Susan Bonner-Weir, PhD, Diabetes Research and Wellness Foundation Professor, Joslin Diabetes Center and Professor of Medicine, Harvard Medical School will present "Evidence of (Re)growth of Human Endocrine Pancreas?" This seminar is hosted by the IU School of Medicine and the Center for Diabetes and Metabolic Diseases." Zoom link: https://iu.zoom.us/s/87501979533<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fiu.zoom.us%2Fs%2F87501979533&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290001720%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=DS4cM366JaoJzxM8bObVfNuLIBjfiRHOfv5Y077gAog%3D&reserved=0> Wed., Nov. 15: Weldon School of Biomedical Engineering Research Seminar, 9:30 a.m., MJIS 1001 or via Zoom. Jane Grande-Allen, PhD, Department of Bioengineering, Rice University, will present "Biophysically Faithful Biomaterial Platforms for Cardiovascular and Intestinal Mechanobiology." Wed., Nov. 15, Advancing Discovery in Antimicrobial Resistance Seminar Series, 12:00 noon, Purdue DRUG, Lobby Conference Room. Dr. Christopher A. Rice, Assistant Professor of Parasitology, Section Head, Microbiology, Immunology and Molecular Genetics, Member of PIDD, PI4D and RCHE, Department of Comparative Pathobiology will present "Awareness, Drug Discovery, and Diagnostic Tools for Pathogenic Free-Living Amoebae." The seminars are sponsored by the College of Veterinary Medicine, Department of Basic Medical Sciences. Thurs., Nov. 16: BME PhD Preliminary Exam Announcement for Elnaz Ghajar-Rahimi, (C. Goergen, advisor), 2:30 p.m., MJIS 2001 and via Zoom. Title: Cardiovascular remodeling due to volume and pressure overload. Wed., Nov. 29: Seminar for Neurotrauma and Diseases, 4:00 p.m., DLR 131. Koji Uchida, Professor of Food Chemistry, University of Tokyo will present "Conversion of Proteins into DNA Mimetics by Reactive Aldehydes." This seminar series is organized by the Center for Paralysis Research and supported by Plexon, the Purdue Institute for Integrative Neuroscience, and Purdue Institute for Drug Discovery. The Zoom link is: https://bit.ly/441Dllq<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fbit.ly%2F441Dllq&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290001720%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=Co22j9PnkSrYFFrjabLKZOGc9Vt8%2FW0VIjMZTkzNn6c%3D&reserved=0>. For additional information, see https://vet.purdue.edu/cpr/ Wed., Nov. 29: Telephone System Update Implemented, 7:00 p.m. Purdue IT is completing the long-running project to retire the phone switch installed more than 25 years ago. Beginning after 7:00 p.m. EST, November 29, changes to the way you use the Purdue West Lafayette telephone systems will be required. See link below for details. Fri., Dec. 1: Indiana Human-Centered Design for Health Seminar Series, 12:00 p.m. via Zoom. Lean about research and best practices in HCD and health, promote the diverse HCD expertise in Indiana, and build a community of HCD researchers and practitioners focused on health, in Indiana and beyond. The speaker will be Jackie Linnes, Associate Professor of Biomedical Engineering at Purdue. Register and learn about upcoming seminars at healthtechquitylab.org/hcd-seminar Fri., Dec. 1: Indiana Life Sciences Conference - "Closing the Gap[ of Health Inequalities," 8:00 a.m. - 3:15 p.m., Roche Diagnostics, Indianapolis. See below for details. Sun., Dec. 3: The Bilsland Dissertation Fellowship nominations due to Tammy Siemers (tsiemers@purdue.edu<mailto:tsiemers@purdue.edu>). See above for details. Thurs., Dec. 14: SAVE THE DATE: 2023 Senior Design Projects Expo and Awards Ceremony, 3:30-5:30 p.m., MJIS. Please mark your calendars and plan to join us to celebrate the achievements of our 2023 senior design teams. The expo will highlight 30 innovative engineering solutions, followed by a live awards ceremony. Fri., March 1: Indiana Human-Centered Design for Health Seminar Series, 12:00 p.m. via Zoom. Lean about research and best practices in HCD and health, promote the diverse HCD expertise in Indiana, and build a community of HCD researchers and practitioners focused on health, in Indiana and beyond. The speaker will be Andrew Miller, Associate Professor and Chair, Department of Hunan-Centered Computing, IUPUI. Register and learn about upcoming seminars at healthtechquitylab.org/hcd-seminar Fri., June 7: Indiana Human-Centered Design for Health Seminar Series, 12:00 p.m. via Zoom. Lean about research and best practices in HCD and health, promote the diverse HCD expertise in Indiana, and build a community of HCD researchers and practitioners focused on health, in Indiana and beyond. The speaker will be Youngbok Hon, Professor, Herron School of Art and Design, IUPUI. Register and learn about upcoming seminars at healthtechquitylab.org/hcd-seminar Resources and further information Mon., Nov. 6: Midwest Mechanics Seminar 2023, 3:30 p.m., ARMS B071. Dr. Alison Marsden, Douglass M. and Nola Leishman Professor of Cardiovascular Disease, Professor of Pediatrics and Bioengineering, and by courtesy of Mechanical Engineering, Institute for Computational and Mathematical Engineering, Stanford University, will present "Multi-physics Modeling of Flow and Cardiac Function in Pediatric Cardiology." Abstract: Congenital heart disease affects 1 in 100 infants and is the leading cause of infant mortality in the US. Among the most severe forms of congenital heart disease is single ventricle physiology, in which the heart develops with only one functional pumping chamber. These patients typically undergo three open chest surgeries, culminating in the Fontan procedure at three years of age. Prior work has extensively explored the use of multiscale models, combining hemodynamics with lumped parameter models of single ventricle physiology to assess surgical methods for all three stages of single ventricle palliation. Here, we present our recent work, which extends traditional models of Fontan hemodynamics to include multiple physical processes and cardiac function. We will discuss our recent progress towards: 1) growth and remodeling of tissue engineered vascular grafts in the Fontan circulation, including a finite element framework for fluid solid growth simulations, and 2) model-driven design of a bioprinted pulsatile conduit to provide a power source for Fontan physiology. Recent methodological advances for generation of vascular networks using optimization will also be described. Finally, we discuss progress and challenges of developing whole heart models incorporating machine learning for image segmentation, fluid mechanics, active contraction, electrophysiology and valves. We will describe open source software and data resources available via the SimVascular project and the Vascular Model Repository. Bio: Alison Marsden is the Douglass M. and Nola Leishman Professor of Cardiovascular Disease in the Departments of Pediatrics, Bioengineering, and, by courtesy, Mechanical Engineering at Stanford University. She is a member of the Institute for Mathematical and Computational Engineering. From 2007-2015 she was a faculty member in Mechanical and Aerospace Engineering at UCSD. She graduated with a BSE degree in Mechanical Engineering from Princeton University in 1998, and a PhD in Mechanical Engineering from Stanford in 2005. She was a postdoctoral fellow at Stanford University in Bioengineering from 2005-07. She was the recipient of a Burroughs Wellcome Fund Career Award at the Scientific Interface in 2007, an NSF CAREER award in 2011. She was elected fellow of AIMBE and SIAM in 2018, the APS DFD in 2020, and BMES in 2021. She is the 2023 recipient of the Van C. Mow medal from the ASME Bioengineering Division. She has published over 160 journal articles and holds leadership roles in the ASME and APS scientific societies. Her research focuses on the development of numerical methods for cardiovascular biomechanics and application of engineering methods to impact patient care in cardiovascular surgery and congenital heart disease. This seminar is sponsored by Purdue's Schools of Aeronautics and Astronautics and Mechanical Engineering. Tues., Nov. 7: EEE Research Seminar, 10:30 a.m., POTR 234 (Fu Room). Dr. Krystel Castillo, Lutcher Brown Chair of Mechanical Engineering, Vice President for Energy Efficiency at the Cybersecurity Manufacturing Innovation Institute, and Director of the Texas Sustainable Energy Research Institute at The University of Texas at San Antonio will present "Integrated Data Analytics Scheme to Enable Energy Efficient Secure Manufacturing and Energy Systems." This seminar is sponsored by Purdue's Department of Environmental and Ecological Engineering. Abstract: This talk presents an overview of a research portfolio focused on the creation of novel data-driven mathematical models that consider the stochasticity and risk in complex systems, and the development of efficient algorithms, to computer optimal and near-optimal solutions for large-scale scenarios. The application domains highlighted during this seminar include energy-efficient cybersecure manufacturing processes and optimization of energy systems, secure real-time/near-real-time data retrieval from a variety of smart sensors and Industrial Internet of Things (IoT) devices to feed energy analytics methods and enable energy efficient manufacturing processes and supply chain networks. The modeling, design and optimization of cost-effective manufacturing systems integrating energy efficiency, emissions and cybersecurity aspects has the potential to be transformative and greatly revolutionize the way that digital manufacturing is executed in the United States. Bio: Dr. Krystel Castillo is currently the Lutcher Brown Chair of Mechanical Engineering and Director of the Texas Sustainable Energy Research Institute (texasenergy.utsa.edu) at the University of Texas at San Antonio. Dr. Castillo serves as VP for Energy Efficiency for the Cybersecurity Manufacturing Innovation Institute (CyManII), a $130M (including cost share) center funded by the Department of Energy. Her research expertise is in Data Analytics and Operations Research; specifically, mathematical programming and optimization applications such as modeling and optimization of clean and sustainable energy systems, cybersecure manufacturing, and supply chain network design. Dr. Castillo has received more than $11 million in grant funding from multiple agencies including USDA, DOE, NSF, EPA, Air Force, Office of Naval Research, among others. She is a member of INFORMS, IISE and ASEE. She received her PhD from Texas Tech University and her ScD from Monterrey Tech. Wed., Nov. 8: Weldon School of BME Research Seminar, 9:30 a.m., MJIS 1001 and via Zoom. Jean-Pierre Mobasser, MD, President, Goodman Campbell Brain and Spine will present "Advancements in Minimally Invasive Lumbar Fusion: A Comparative Review." Abstract: Abstract: Minimally invasive lumbar fusion offers a progressive alternative to traditional open spinal surgery, addressing conditions such as degenerative disc disease, spondylolisthesis, and scoliosis. Favored for its potential to minimize blood loss, reduce muscular trauma, and expedite postoperative recovery, this method stands at the forefront of spinal surgical interventions. Our upcoming discussion will delve into various minimally invasive lumbar fusion strategies, scrutinizing their respective benefits and limitations to inform clinical practice. Biography: Jean-Pierre Mobasser, MD was born in England and immigrated to the United States when he was 2 years old. He grew up in Atlanta, Georgia and then attended the University of Pennsylvania for his undergraduate degree. He obtained his medical degree from the Medical College of Georgia and completed his residency in neurosurgery and fellowship in complex and minimally invasive spine surgery from the University of Tennessee. Dr. Mobasser moved to Indiana to practice with the former Indianapolis Neurosurgical Group (ING), which later became Goodman Campbell Brain and Spine. Dr. Mobasser is board certified by the North American Board of Neurological Surgery and is a founding member of the Society for Minimally Invasive Spine Surgery, and a member of the Congress of Neurological Surgeons, American Association of Neurological Surgeons and the Indiana Neurological Society. Dr. Mobasser has particular expertise on image-guided spinal navigation and minimally invasive spine surgery, and has lectured all over the world on these subjects. His clinical interests include back and neck pain, minimally invasive spine surgery, spinal tumor surgery, degenerative spinal conditions and artificial disc surgery. Dr. Mobasser is currently the team neurosurgeon for the Indiana Pacers and has served as an Unaffliated Neurotrauma Consultant for the N.F.L. Dr. Mobasser is currently serving his second term as President of Goodman Campbell Brain & Spine, one of the largest Neurosurgical Groups in North America. Dr. Mobasser is also the a Past President of the Society of Minimally Invasive Spine Surgery. ~ BME Host: Young Kim ~ NOTE: Students registered for the seminar are expected to attend in-person. Zoom link: https://purdue-edu.zoom.us/j/5593290378?pwd=eFBOZFlNTU50ZDA2S2gwcnpyOWIwUT09<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-edu.zoom.us%2Fj%2F5593290378%3Fpwd%3DeFBOZFlNTU50ZDA2S2gwcnpyOWIwUT09&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290001720%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=WdEvsmZHTWzSVaOO38PkKl9%2BBAB5WJmPAQTuJlFYD6Q%3D&reserved=0> Wed., Nov. 8: Diabetes Research Virtual Seminar Series, 2:00 p.m., via Zoom. Arleen F. Brown, MD, PhD, Professor of Medicine, General Internal Medicine and Health Services Research and Co-Director, UCLA Clinical & Translational Science Institute and Community Engagement & Research Program will discuss "Structural Interventions to Address Cardiometabolic Disease Disparities." In this seminar, Dr. Brown will: * Describe conceptual frameworks for understanding and intervening on cardiometabolic disease disparities * Define structural interventions * Key features and examples of structural interventions with the potential to promote equity in cardiometabolic conditions * Challenges to developing and deploying structural interventions * Opportunities and Recommendations for developing and implementing structural interventions to promote equity for cardiometabolic conditions. This seminar series is organized by the Diabetes Research Centers and Centers for Diabetes Translation Research. To view previous webinars or register for the "meet the Speaker" meeting, please go to https://diabetes-virtual-seminar.org/<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdiabetes-virtual-seminar.org%2F&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290001720%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=4QnqSXQeP0l5Qo11thQV49vfkX9thSM0y3EfgzJCPHY%3D&reserved=0> Zoom link: https://zoom.us/j/91323894836 Thurs., Nov. 9: BME PhD Preliminary Exam for Grigorii Rudakov (T. Kinzer-Ursem and L. Green, co-advisors). Everyone is invited to attend the public presentation beginning at 9:00 am in MJIS 2001. For coffee and bagels come 15 minutes early. Title: DNA Tetrahedron Design Optimization for Efficient Drug Delivery Through the Blood-Brain Barrier. Committee: Dr. Tamara Kinzer-Ursem (co-chair), Dr. Leopold Green (co-chair), Dr. Chengde Mao (Chemistry), Dr. Gregory Knipp (Pharmacy) Abstract: In our proposed study, we aim to optimize the design of Tetrahedral DNA Nanomaterials (TDN) to effectively deliver drugs through the Blood-Brain Barrier (BBB). Starting with two classical TDN structures, we alter the design by changing the size, structure (one or two double-stranded DNA helices on the edges), and attached DNA aptamers for receptor-medicated endocytosis pathway to study the influence of these factors on cellular uptake, stability of TDNs, toxicity, and potential delivery efficiency. We plan on testing our materials in vitro HEK293, SUM159, mice cortical, and human astrocytes cellular lines, as well as in the human BBB in vitro model. To study the biodistribution and tissue toxicity, we will perform in vivo tests of the most prominent TDNs designs on the C57BL/6-wt mouse model, harvest the tissues, and run histology analysis with H&E stains. The TDNs concentration will be measured by measuring implemented into the DNA strands cyanine 3 and 5 dyes fluorescence and the stability will be estimated by Fluorescence Resonance Energy Transfer measurements. If we succeed in our work, we will develop an effective, exceptionally biocompatible, and stable nanomaterial with great potential applications in drug delivery through BBB, brain imaging, and gene therapy. We expect the main application of this nanomaterial to be in treating and mitigating the symptoms of Alzheimer's and other neurodegenerative diseases, as the low BBB permeability poses the main challenge in the way of studying and treating these illnesses. Thurs., Nov. 9: Seminars in Hearing Research, 12:00 noon, Nelson Hall, Room 1215. Samantha Hauser and Andrew Sivaprakasam will present "Audiology Research Diagnostics Core (ARDC) & Data Repository: Big Data Analysis for Hearing Research." Abstract: Many labs on Purdue's campus, whether they study hearing directly or not, run (or wish they could run) basic auditory diagnostics to ensure their research participants have appropriate hearing profiles for the study. This data, however, is often not used beyond establishing a subject's inclusion in a study and each lab's test battery may lack standardization or may be incomplete due to resource limitations. To address these problems, the Audiology Research Diagnostics Core (ARDC) was designed to optimize the collection of high-quality audiologic data and to reduce the barrier-to-entry for hearing evaluations (e.g., in non-auditory labs). Not only does the ARDC function as a core facility to facilitate comprehensive hearing evaluations, but it drives the Audiology Research Diagnostics Core Repository (ARDCR). The ARDCR will include data collected in the ARDC as well as across other hearing labs on campus to accumulate large scale datasets for future analyses. We will demonstrate how the ARDCR can also be used by Purdue researchers to recruit participants with specified profiles of hearing, along with the current structure and formatting of this data. As the ARDC is in its early stages, we will continue a discussion about how labs can best engage with the ARDC and solicit feedback regarding ARDC logistics. Visit https://engineering.purdue.edu/TPAN/hearing/ardc for more information. This year's SHRP schedule is available here: https://purdue.edu/TPAN/hearing/shrp_schedule<https://nam04.safelinks.protection.outlook.com/?url=http%3A%2F%2Fogww.mj.am%2Flnk%2FAU8AAEukm7AAAchk2HAAALFJlZgAAYCsFQMAnDnUAATD7ABh_T90ybQipdUVQZ20y9CAzjYFPgAEkSo%2F5%2FVzPUtXKo0Dowllp_TK_BrQ%2FaHR0cHM6Ly9wdXJkdWUuZWR1L1RQQU4vaGVhcmluZy9zaHJwX3NjaGVkdWxl&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290001720%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=QecYaLurnFmHmI%2FOkswVGl8fea8eeBu2%2BVzuf6aGj8s%3D&reserved=0> Titles and abstracts of all SHRP talks are here: https://purdue.edu/TPAN/hearing/shrp_abstracts<https://nam04.safelinks.protection.outlook.com/?url=http%3A%2F%2Fogww.mj.am%2Flnk%2FAU8AAEukm7AAAchk2HAAALFJlZgAAYCsFQMAnDnUAATD7ABh_T90ybQipdUVQZ20y9CAzjYFPgAEkSo%2F6%2Fa2vUEcd_J6SQbZdR8Ley5Q%2FaHR0cHM6Ly9wdXJkdWUuZWR1L1RQQU4vaGVhcmluZy9zaHJwX2Fic3RyYWN0cw&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290001720%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=ARx7vNhkpzyO4N9lZz0nBSZYB6KmYHLZIJ6tkW6QAPc%3D&reserved=0> Wed., Nov. 15: Weldon School of Biomedical Engineering Research Seminar, 9:30 a.m., MJIS 1001 or via Zoom. Jane Grande-Allen, PhD, Department of Bioengineering, Rice University, will present "Biophysically Faithful Biomaterial Platforms for Cardiovascular and Intestinal Mechanobiology." Abstract: The material behavior of many biological tissues is due to their unique microstructural arrangements of fibrous extracellular matrix (ECM) proteins, i.e., collagen and elastin, within the more amorphous matrix. The orientation of these fibers, and their segregation into discrete regions within the tissues, often gives rise to anisotropy and unique biological stress-strain behavior that enables the essential function of the tissues. Layered or segregated structuring allow hierarchical tissue organization in a manner designed to withstand external forces efficiently while protecting more delicate tissues and cells from damage. These structure-function relationships within biological tissues have been studied for decades but have not been widely translated into the creation of biomimetic scaffolds for use in tissue engineering and in vitro analyses of cell and tissue biology. The Grande-Allen research group has focused on integrating these structural and material characteristics into hydrogel and fibrous biomaterials using a range of fabrication techniques including molding, photolithography, electrospinning, and 3D printing. The majority of our investigations have addressed heart valve disease, which is widely prevalent in our society, with valve replacement or repair in almost 100,000 people in the United States and 275,000 people worldwide each year. More recently, we have translated our fabrication strategies to generate biomaterial platforms for investigating intestinal epithelial cell biology and enteric diseases. Biography: Jane Grande-Allen is the Isabel Cameron Professor of Bioengineering at Rice University. Her research group investigates the structure-function-environment relationship of soft connective tissues through bioengineering analyses of the extracellular matrix and cell mechanobiology, with a focus on cardiovascular and intestinal diseases, as described in >180 peer-reviewed publications. Dr. Grande-Allen received a BA in Mathematics and Biology from Transylvania University in 1991 and a PhD in Bioengineering from the University of Washington in 1998. After postdoctoral research in Biomedical Engineering at the Cleveland Clinic, she joined Rice University in 2003 and was promoted to full professor in 2013. Dr. Grande-Allen is a Fellow of AIMBE, IAMBE, BMES, AAAS, AHA, and the Society for Experimental Mechanics. She served on the BMES Board of Directors and Executive Board from 2009-2022 and was BMES Secretary from 2020-2022. Dr. Grande-Allen also serves on the research committee for the American Heart Association. ~ BME Host: Deva Chan ~ NOTE: Students registered for the seminar are expected to attend in-person. Zoom link: https://purdue-edu.zoom.us/j/95124789878?pwd=S0x0VW5Vd3VaMVc1LytlL0NJU1FYUT09<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-edu.zoom.us%2Fj%2F95124789878%3Fpwd%3DS0x0VW5Vd3VaMVc1LytlL0NJU1FYUT09&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290001720%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=YRI4dLHmjGdnJkBrpgWWF9mKLHTDgnDFfby48z9NxvM%3D&reserved=0> Thurs., Nov. 16: BME PhD Preliminary Exam Announcement for Elnaz Ghajar-Rahimi, (C. Goergen, advisor), 2:30 p.m., MJIS 2001 and via Zoom. Title: Cardiovascular remodeling due to volume and pressure overload. Advisory Committee: Craig J. Goergen, Chair; Vitaliy L. Rayz; Fiona R. Kolbinger; Kyoko Yoshida; Benjamin J. Landis Abstract: Volume and pressure overload induce cardiac remodeling that may lead to heart failure when left untreated. Conditions such as pregnancy, lactation, and aortic stenosis are common etiologies of pressure and volume overload. However, sex- and female-specific variables and recovery are often overlooked in studies of cardiac overload. One of the most common modalities used to study cardiac function, 2D ultrasound, does not fully capture changes that may occur to heart shape and performance given that it is limited to a single imaging plane. To improve our understanding of pressure and volume overload we propose mouse models of lactation, chronic hypertension with pregnancy, and reversible transverse aortic constriction. We hypothesize that four-dimensional ultrasound will reveal the unique ways in which volume and pressure overload in the setting of pregnancy, lactation, and aortic constriction affect cardiac remodeling. Completion of this study will broaden the horizons of maternal cardiac health and lay the framework for future exploration of sex as a biological variable in CVD studies. Zoom link: https://purdue-edu.zoom.us/j/94088456640<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue-edu.zoom.us%2Fj%2F94088456640&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290001720%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=0C5JmYkHGE%2Bym09%2FAG7UxeQAd2%2B%2Bn%2BNR4qP29YIKXvE%3D&reserved=0> Wed., Nov. 29: Telephone System Update Implemented, 7:00 p.m. Purdue IT is completing the long-running project to retire the phone switch installed more than 25 years ago. Beginning after 7:00 p.m. EST, November 29, the following changes to the way you use the Purdue West Lafayette telephone systems will be required. 1. Moving to utilize 10-digit dialing for all outgoing calls. This dialing method requires users to dial 1 + the area code of the person being called as part of the dialing process. However, 5-digit internal to campus dialing will remain the same. This is a requirement dictated to use by our Carrier and is now standard nationwide. If you would like to know more about 10-digit dialing, the following website contains more information: https://www.fcc.gov/consumers/guides/ten-digit-dialing<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.fcc.gov%2Fconsumers%2Fguides%2Ften-digit-dialing&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290157996%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=e%2B%2FtfaqjYSthXh2mZ4usvDBYtlSS7wfgj1tIFluvHFM%3D&reserved=0> * Local AND Long Distance call: 7 + 1 + 10 digit = 7-1-(317)-555-5555 * International call: 7 + 011 + country code + local number 2. International Calling: The current process using international access codes will no longer be supported. If you currently have an international calling code and need the ability to dial internationally then please complete the form at: https://purdue.ca1.qualtrics.com/jfe/form/SV_1FVkar7IS9zKvjg<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fpurdue.ca1.qualtrics.com%2Fjfe%2Fform%2FSV_1FVkar7IS9zKvjg&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290157996%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=pxiJKTv7cfIMkVMBnKwIwrEaYB8VCaDLaP7CzwqlDbk%3D&reserved=0> Purdue IT strives to provide a top-quality telecommunications system and appreciates your support as we continue to upgrade our services and provide a highly reliable service. If you should have questions or concerns, please contact it@purdue.edu<mailto:it@purdue.edu>. Fri., Dec. 1: Indiana Life Sciences Conference - "Closing the Gap[ of Health Inequalities," 8:00 a.m. - 3:15 p.m., Roche Diagnostics, Indianapolis. [cid:image002.jpg@01DA1160.FDBF0D60] [cid:image003.jpg@01DA1160.FDBF0D60] Closing the Gap of Health Inequalities Friday, December 1 Roche Diagnostics, Indianapolis Addressing the persistent disparities in health and wellness among different populations is an issue that can't be ignored. While the healthcare cost implications are significant, the societal and economic implications are even more so. This conference will examine ongoing efforts to improve both the delivery of healthcare and health-related social factors like access to healthy foods, access to transportation and safe neighborhoods, which influence health outcomes. AGENDA 8:00-9:00am Registration & Breakfast 9:00-9:15am Welcome & Introduction 9:15-10:15am Opening Keynote- Defining Health Inequalities Paul K. Halvorsen, Professor & Founding Dean, Richard M. Fairbanks School of Public Health, Indiana University 10:15-10:30am Break 10:30am-12:00pm Panel- Provider Perspective & Initiatives Brownsyne Tucker Edmonds, M.D., Associate Professor of Obstetrics & Gynecology & Associate Dean for Health Equity Research, IU School of Medicine & VP Chief Health Equity Officer, IU Health Edmond Davis, Senior Director, Health Equity, Zimmer Biomet TBA 12:00-12:45pm Break for Lunch 12:45-1:30pm Luncheon Keynote- Snapshots of Ongoing Initiatives Paige Bingham, Director, Close the Gap Ariana McGee, Founder & CEO, Navigate Maternity Holly Wood, Senior Director, Health Equity Initiative, Purdue University TBA 1:30-3:00pm Panel- Payer Perspective & Initiative Antoniette Holt, Strategic Equity Officer & Division Director, Office of Minority Health, Indiana Department of Health Darryl Lockett, Health Equity Director, Anthem Indiana Medicaid Andy Vector, President of Benefits Consulting & Chief Growth Officer, MJ Insurance TBA 3:00-3:315pm Wrap-Up CLICK FOR MORE INFO & REGISTER NOW<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fcl.s6.exct.net%2F%3Fqs%3D659daadefdc761a86305a0c77c32a2c9fbacc3d13b7b26bee7e2cc76ccf6f3cc2a8a21f9ba52da4816369f4ea010c9b1be25dffba0d00f89&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290157996%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=hcV33tSaCduHEagyVLo7F7wRbGLLOP%2BDEaDmYjN6Z9s%3D&reserved=0> Button Text<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fcl.s6.exct.net%2F%3Fqs%3D659daadefdc761a81ada2497fad366ad0d870cda754f1ec1392d59d77e408a91b961f72d88d95c389462c07e0ec220fa18313046d6bc5645&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290157996%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=2FH0AlgB5bLu0aVcQwnkjrmr4aPQnjr5acbitkr8ZKw%3D&reserved=0> [cid:image004.png@01DA1160.FDBF0D60] BME Weekly Research Seminars Week # Date Speaker Title Host Website 12 11/8/2023 Jean-Pierre Mobasser Affiliate Clinical Faculty Indiana University Young Kim https://www.goodmancampbell.com/our-team/team-member/jean-pierre-mobasser-md<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.goodmancampbell.com%2Four-team%2Fteam-member%2Fjean-pierre-mobasser-md&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290157996%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=MKsMzpcEOAfn2uvowipBf4pbVXj3AsEurvRILGHIdEs%3D&reserved=0> 13 11/15/2023 Jane Grande- Allen Isabel C. Cameron Professor of Bioengineering, Rice University Deva Chan https://profiles.rice.edu/faculty/k-jane-grande-allen<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fprofiles.rice.edu%2Ffaculty%2Fk-jane-grande-allen&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290157996%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=AMHRH%2B4BD03hE5lT%2B7ZjdWwl8PgFK88TXfOYUNyDAr0%3D&reserved=0> 14 11/29/2023 Sarah Wiehe Jean and Jerry Bepko Professor of Pediatrics Indiana University School of Medicine George Wodicka https://medicine.iu.edu/faculty/16722/wiehe-sarah<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmedicine.iu.edu%2Ffaculty%2F16722%2Fwiehe-sarah&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290157996%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=G9lXxGMrpumn8AMpUyFQ9e6ZNLJx7zboFbnXs7cRSHQ%3D&reserved=0> 15 12/6/2023 Robbee Wedow Assistant Professor of Sociology and Data Science, Purdue University Department of Sociology David Umulis https://www.robbeewedow.com/?_ga=2.88497945.389094989.1679581193-1816225309.1603576015<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.robbeewedow.com%2F%3F_ga%3D2.88497945.389094989.1679581193-1816225309.1603576015&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290157996%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=2uC4%2F8mV6JXjD%2FGAa0qku283ZFG56NxPcL2TVAf86bo%3D&reserved=0> Postdoctoral Fellow Opportunity - IUSM Emergency Medicine The laboratory of Dr. Nathan J. Alves, PhD, within the Department of Emergency Medicine at the Indiana University School of Medicine (IUSM), is seeking a highly motivated and independent post-doctoral research fellow. Dr. Alves is a Chemical and Biomolecular Engineer, Associate Professor and the Director of Translational Research for the Department of Emergency Medicine in addition to having an affiliate faculty appointment at Purdue University in Biomedical Engineering. The Alves Lab explores highly interdisciplinary research interests applying engineering and biophysical principles and designs to create translational technologies and treatments in the area of blood coagulation and fibrinolysis. The primary focus of research in the laboratory is to develop targeted clot digesting therapeutic agents to more safely digest clinically relevant blood clots to treat pulmonary embolism (PE, blood clots in the lungs), deep vein thrombosis (DVT), and ischemic stroke. This interdisciplinary research utilizes diverse enzyme assays, chemical synthesis, blood clot formation and digestion assays under shear, and other novel testing/delivery platforms that include multivalent branched molecules and nanoparticle drug delivery systems. Projects Include: (1) Leveraging multivalency to modulate enzyme activity and improve inhibitor selectivity (nanoparticle drug delivery and targeting). (2) Ex-vivo flowing models of clot digestion under shear using in-vivo like fluorescently labeled blood clots from human whole blood. (3) Development of novel fibrinolytic diagnostics tools to assess coagulation state. (4) Mouse models of clot formation/targeting/digestion utilizing intravital microscopy. (5) Study the effects of environmental microplastic exposure on coagulation/fibrinolysis. Projects are funded both externally and internally. For additional information and to apply, go to: https://indiana.peopleadmin.com/postings/19651<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Findiana.peopleadmin.com%2Fpostings%2F19651&data=05%7C01%7Cbmeroundtable-list%40ecn.purdue.edu%7C59287b2131f747034ca908dbdfa209fe%7C4130bd397c53419cb1e58758d6d63f21%7C0%7C0%7C638349659290157996%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=Z3GmbbiFNC%2BuFWGqmBD5pvCVmyJZQvLsFfbZKR9z3Cg%3D&reserved=0> -- Bmeroundtable-list mailing list Bmeroundtable-list@ecn.purdue.edu https://engineering.purdue.edu/ECN/mailman/listinfo/bmeroundtable-list