BEGIN:VCALENDAR METHOD:REQUEST PRODID:Microsoft Exchange Server 2010 VERSION:2.0 BEGIN:VTIMEZONE TZID:Eastern Standard Time BEGIN:STANDARD DTSTART:16010101T020000 TZOFFSETFROM:-0400 TZOFFSETTO:-0500 RRULE:FREQ=YEARLY;INTERVAL=1;BYDAY=1SU;BYMONTH=11 END:STANDARD BEGIN:DAYLIGHT DTSTART:16010101T020000 TZOFFSETFROM:-0500 TZOFFSETTO:-0400 RRULE:FREQ=YEARLY;INTERVAL=1;BYDAY=2SU;BYMONTH=3 END:DAYLIGHT END:VTIMEZONE BEGIN:VEVENT ORGANIZER;CN=Crystal D O'Neal:mailto:cdoneal@purdue.edu ATTENDEE;ROLE=REQ-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=bmegradst udents-list@ecn.purdue.edu:mailto:bmegradstudents-list@ecn.purdue.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Matthew P eter Ward:mailto:mpward@purdue.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Audrey H Sherwood:mailto:asherwo@purdue.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Darla Daw n Wetli:mailto:ddwetli@purdue.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Robin D T erwilliger:mailto:rterwill@purdue.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Rebecca P eer:mailto:peerb@purdue.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Leza R De llinger:mailto:lrdellin@purdue.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Teresa L DeMien:mailto:tdemien@purdue.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Victoria Ann Wunderlich:mailto:vwunder@purdue.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Lisa A St acey:mailto:staceyl@purdue.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Joshua Go nzalez:mailto:jgonzal@purdue.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Kellie A Reece:mailto:kreece@purdue.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Lori Elai ne Griffey:mailto:legriffe@purdue.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Jurss, Ka ren L":mailto:kjurss@purdue.edu ATTENDEE;ROLE=REQ-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=bmefacult y-list@ecn.purdue.edu:mailto:bmefaculty-list@ecn.purdue.edu ATTENDEE;ROLE=REQ-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Arezoo Ar dekani:mailto:ardekani@purdue.edu ATTENDEE;ROLE=REQ-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Ilias Bil ionis:mailto:ibilion@purdue.edu ATTENDEE;ROLE=REQ-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Fang Huan g:mailto:huang892@purdue.edu ATTENDEE;ROLE=REQ-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Hector Go mez:mailto:hectorgomez@purdue.edu ATTENDEE;ROLE=REQ-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Luis Solo rio:mailto:lsolorio@purdue.edu ATTACH:CID:D52CF727606E6044A1A37DFD6F50A2DA@namprd22.prod.outlook.com ATTACH:CID:F1FD7823F78476479F0773261BBA70D2@namprd22.prod.outlook.com ATTACH:CID:image003.jpg@01DCAFB0.65C3D4F0 DESCRIPTION;LANGUAGE=en-US:Please feel free to share with any/all who may b e interested!\n\nBME Seminar\nWednesday\, March 11\, 2026\n3:00 – 4:00 p m\, MJIS 2001\nMicrosoft Teams meeting\nJoin: https://teams.microsoft.com/ meet/29439842767101?p=6YaWmmFKW0hKsRNqo2\nMeeting ID: 294 398 427 671 01\nPasscode: ox2ok3mp\n\n“Precisi on Nanomaterials for Cancer Immunotherapy and Bioengineering”\n\n[cid:im age003.jpg@01DCAFB0.65C3D4F0]\n\nQiangqiang Shi\, PhD\nPostdoctoral Resear cher in Bioengineering\nUniversity of Pennsylvania\n\n\nAbstract: Precisio n nanomaterials are transforming bioengineering by making therapeutic func tion programmable and measurable in vivo. In this seminar\, I will present three complementary efforts that use molecularly defined design to progra m biological function and enable quantitative in vivo readouts. First\, I will describe prodrug-tethered lipid nanoparticles (LNPs) that couple cont rolled intracellular drug release with cytokine mRNA delivery to amplify a ntitumor immunity while improving safety. Second\, I will discuss lung-tar geted intravenous mRNA vaccination that redirects antigen expression to th e lung to promote local immune surveillance and durable tumor protection. Third\, I will introduce precision chemical barcode system for nanoparticl es encoding and quantification. Together\, these studies position precisio n and encoded nanomaterials as a new operating paradigm for nanobiomateria ls.\n\nBio: Qiangqiang Shi\, is a postdoctoral researcher in Bioengineerin g at the University of Pennsylvania in Prof. Michael Mitchell’s laborato ry. His research centers on precision nanomaterials for drug and mRNA deli very\, with an emphasis on cancer immunotherapy. He develops prodrug-tethe red lipid nanoparticles (LNPs) for controlled immunomodulation\, lung-targ eted intravenous mRNA vaccine strategies to program local anti-tumor immun ity. He also develops chemical barcode system that enables built\, read\, and encode information into nanoparticles. He has authored first/co-first- author papers in Nature Nanotechnology\, Nature Chemistry\, Nature Reviews Cancer\, and PNAS and other leading journals.\n\n________________________ ________________________________________________________\nMicrosoft Teams meeting\nJoin: https://teams.microsoft.com/meet/29439842767101?p=6YaWmmFKW 0hKsRNqo2\nMeeting ID: 294 398 427 671 01\nPasscode: ox2ok3mp\n________________________________\nNeed help?< https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Faka.ms%2 FJoinTeamsMeeting%3Fomkt%3Den-US&data=05%7C02%7Cbmegradstudents-list%40ecn .purdue.edu%7Cb607dc68d9d6480625b708de7de9a42d%7C4130bd397c53419cb1e58758d 6d63f21%7C1%7C0%7C639086639628467796%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hc GkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ% 3D%3D%7C0%7C%7C%7C&sdata=A5bapRjjnRmnMIcTDAdVhFXaSdst8t7YgG9tXKgFpQQ%3D&re served=0> | System reference\nDial in by phone\n+1 219-293-4410\,\,10262219# United States\, Ga ry\nFind a local number \nPhone conference ID: 102 622 19#\nJoin on a video conferencing device\nT enant key: purdue@m.webex.com\nVideo ID: 119 63 4 603 8\nMore info\nFor organizers: Meeting options | Reset dial-in PIN\n___________________________________________________ _____________________________\n\n UID:040000008200E00074C5B7101A82E00800000000F0699D2914ABDC01000000000000000 010000000068B06A8A50E2D4896A7486207B56DDC SUMMARY;LANGUAGE=en-US:Qiangqiang Shi - Seminar Purdue AI‑Driven Biomolec ular Design\, Biotech & Computational Biology Position DTSTART;TZID=Eastern Standard Time:20260311T150000 DTEND;TZID=Eastern Standard Time:20260311T160000 CLASS:PUBLIC PRIORITY:5 DTSTAMP:20260309T143913Z TRANSP:OPAQUE STATUS:CONFIRMED SEQUENCE:2 LOCATION;LANGUAGE=en-US:MJIS 2001/\; Microsoft Teams Meeting X-MICROSOFT-CDO-APPT-SEQUENCE:2 X-MICROSOFT-CDO-OWNERAPPTID:449394666 X-MICROSOFT-CDO-BUSYSTATUS:TENTATIVE X-MICROSOFT-CDO-INTENDEDSTATUS:BUSY X-MICROSOFT-CDO-ALLDAYEVENT:FALSE X-MICROSOFT-CDO-IMPORTANCE:1 X-MICROSOFT-CDO-INSTTYPE:0 X-MICROSOFT-ONLINEMEETINGINFORMATION:{"OnlineMeetingChannelId":null\,"Onlin eMeetingProvider":3} X-MICROSOFT-SKYPETEAMSMEETINGURL:https://teams.microsoft.com/l/meetup-join/ 19%3ameeting_YzE4MTdlZGItYWRjMS00OWNmLTgzMTktOTczOWE5MzAxMmY5%40thread.v2/ 0?context=%7b%22Tid%22%3a%224130bd39-7c53-419c-b1e5-8758d6d63f21%22%2c%22O id%22%3a%22df347d6f-ac43-4e29-a82a-129a7532453a%22%7d X-MICROSOFT-SCHEDULINGSERVICEUPDATEURL:https://api.scheduler.teams.microsof t.com/teams/4130bd39-7c53-419c-b1e5-8758d6d63f21/df347d6f-ac43-4e29-a82a-1 29a7532453a/19_meeting_YzE4MTdlZGItYWRjMS00OWNmLTgzMTktOTczOWE5MzAxMmY5@th read.v2/0 X-MICROSOFT-SKYPETEAMSPROPERTIES:{"cid":"19:meeting_YzE4MTdlZGItYWRjMS00OWN mLTgzMTktOTczOWE5MzAxMmY5@thread.v2"\,"private":true\,"type":0\,"mid":0\," rid":0\,"uid":null} X-MICROSOFT-DONOTFORWARDMEETING:FALSE X-MICROSOFT-DISALLOW-COUNTER:TRUE X-MICROSOFT-REQUESTEDATTENDANCEMODE:DEFAULT X-MICROSOFT-ISRESPONSEREQUESTED:FALSE X-MICROSOFT-LOCATIONS:[ { "DisplayName" : "MJIS 2001/"\, "LocationAnnotatio n" : ""\, "LocationSource" : 0\, "Unresolved" : true\, "LocationUri" : "" }\, { "DisplayName" : "Microsoft Teams Meeting"\, "LocationAnnotation" : " "\, "LocationSource" : 0\, "Unresolved" : false\, "LocationUri" : "" } ] BEGIN:VALARM DESCRIPTION:REMINDER TRIGGER;RELATED=START:-PT15M ACTION:DISPLAY END:VALARM END:VEVENT END:VCALENDAR