BME WEEKLY ROUNDTABLE

WEEK OF November 13, 2023

 

 

INTERIM HEAD¡¯S NOTE

 

Several BME faculty won the Acorn Award recently, given to investigators in recognition of their accomplishment in obtaining an external sponsored award of $1 million or more. Please see lists of awardees by year. To find out who they are, please visit

https://www.purdue.edu/research/oevprp/researcher-resources/awards/seed-for-success/

Congratulations!

 

We are coming down the home stretch. Everyone, please take care and please be mindful of the changes and development among students you teach when you interact with them.

 

We have gotten additional clarity on the staff side of our academic unit on the PU – Indy campus. We are approved to have one academic advisor, one administrative assistant, one research lab operations person, and one instructional lab operations person. Vitaliy and I are collecting information from the teaching faculty there to clarify the job responsibilities of the instructional lab operations person. We hope to have sufficient clarity by our next faculty meeting.

 

The Bilsland Dissertation Fellowship is a wonderful way to recognize our graduate students. as they get ready to finish up their PhD research. More information is in the Graduate Program Update section. 

 

UPCOMING IMPORTANT DATES

 

Week of November 13

 

Mon., Nov. 13:  Center for Diabetes and Metabolic Diseases Research Seminar Series/Diabetes Day, 12:00 p.m., R4-101 (Indianapolis) and via Zoom. Susan Bonner-Weir, PhD, Diabetes Research and Wellness Foundation Professor, Joslin Diabetes Center and Professor of Medicine, Harvard Medical School will present ¡°Evidence of (Re)growth of Human Endocrine Pancreas?¡±  This seminar is hosted by the IU School of Medicine and the Center for Diabetes and Metabolic Diseases.¡±  Zoom link:  https://iu.zoom.us/s/87501979533

 

Wed., Nov. 15:  Weldon School of Biomedical Engineering Research Seminar, 9:30 a.m., MJIS 1001 or via Zoom. Jane Grande-Allen, PhD, Department of Bioengineering, Rice University, will present ¡°Biophysically Faithful Biomaterial Platforms for Cardiovascular and Intestinal Mechanobiology.¡±

 

Wed., Nov. 15, Advancing Discovery in Antimicrobial Resistance Seminar Series, 12:00 noon, Purdue DRUG, Lobby Conference Room. Dr. Christopher A. Rice, Assistant Professor of Parasitology, Section Head, Microbiology, Immunology and Molecular Genetics, Member of PIDD, PI4D and RCHE, Department of Comparative Pathobiology will present ¡°Awareness, Drug Discovery, and Diagnostic Tools for Pathogenic Free-Living Amoebae.¡±  The seminars are sponsored by the College of Veterinary Medicine, Department of Basic Medical Sciences.

 

Thurs., Nov. 16: BME PhD Preliminary Exam Announcement for Elnaz Ghajar-Rahimi, (C. Goergen, advisor), 2:30 p.m., MJIS 2001 and via Zoom. Title: Cardiovascular remodeling due to volume and pressure overload.

 

Thurs., Nov. 16Seminars in Hearing Research, 12:00 noon, Nelson Hall, Room 1215. Andrew Sivaprakasam, MD/PhD Trainee, Indiana University School of Medicine will present ¡°Physiological and Perceptual Investigations of Place and Time Coding of Pitch Across Species: Preliminary Findings and Experimental Framework.¡±

 

Fri., Nov. 17: BME PhD Preliminary Exam Announcement for Eugene S. Kim (T. Kinzer-Ursem, advisor). Everyone is invited to attend the public presentation beginning at 1:00 p.m. in MRGN 121. Title: ¡°The Role of CaMKII¥â-DrebrinA Binding in F-actin Stabilization in Dendritic Spines.¡±

 

Fri., Nov. 17:  BME PhD Defense Announcement for Tyler Diorio (V. Rayz, advisor). Everyone is invited to attend the public presentation beginning at 3:30pm in MJIS 2001 and via Zoom. Title of Thesis Research: Brain Biomechanics: Multiscale Mechanical Changes in the Brain and its Constituents.

 

MJIS ALERT

 

As of Wed., Nov. 29: Telephone System Update Implemented, 7:00 p.m.  Purdue IT is completing the long-running project to retire the phone switch installed more than 25 years ago. Beginning after 7:00 p.m. EST, November 29, changes to the way you use the Purdue West Lafayette telephone systems will be required, including required use of area codes for ALL calls. See link below for details.

 

ACADEMIC PROGRAMS ALERT

 

Re: final exam accommodations. We have a number of students who may need accommodations for final exams and faculty need to be proactive in scheduling with the Testing Center if they plan to use that.

 

Below is some important information instructors should know if they choose to have Purdue Testing Services (PTS) administer their accommodated exams.

*If you had already submitted a TIF for your final prior to receiving this email, PTS staff updated your TIF to the correct exam group


Another email will be sent closer to finals week with more important information regarding delivery and return methods. Instructors may find up-to-date information as well as step-by-step guides on
our website.

Thanks,

Kelsey Jordan, M.S.
she/her/hers
Director, 
Purdue Testing Services

 

ALSO:

We are now more than halfway through the Fall term so here are some reminders as we round the corner to final grading:

 

FERPA, GLBA, Protecting SSNs, and Data Handling all must be current at the time of grade entry to prevent any roadblocks.

 

https://www.purdue.edu/registrar/faculty/grading/index.html

Full Term (16 Weeks) and Second Eight-Week Session (meeting between October 18 and December 16)

Grade entry begins at 8 a.m. December 1 and ends at 5 p.m. December 19.

 

GRADUATE PROGRAM UPDATE

 

Fellowship Opportunity

The Bilsland Dissertation Fellowship provides support for outstanding PhD candidates in their final year or semester of doctoral degree completion. The goal of the fellowship is to allow exceptional candidates to focus exclusively on finishing their dissertation. The Graduate School Fellowship Manual has additional details https://www.purdue.edu/gradschool/fellowship/fellowship-resources-for-staff/index.html

 

Note: Students in other schools outside of BME should follow those schools¡¯ procedures.

 

Due Date: Sunday, December 3rd   (tsiemers@purdue.edu)

 

Student Eligibility

 

Application Package Should Include the following in one PDF:

 

 

Salary & Usage:

 

The announcement will go out to the students as well.  Please let me know if you have any questions.

 

Excellence in Teaching Awards Competition

Applications are now being accepted for the Midwestern Association of Graduate Schools (MAGS) 2024 Excellence in Teaching Awards Competition. The University is eligible to nominate one masters-level and one Ph.D.-level student for each award that includes a citation and a $750 honorarium that will be presented at the MAGS annual meeting on April 3-5, 2024. Interested students must submit their application materials to the Graduate School by Friday, December 1, 2023, at 5:00 p.m. for consideration.

 

Award Details

 

Submission Details

Graduate students wishing to be considered for this award must submit a single PDF document that includes:

 

Timeline toward nomination

 

Questions?

Please contact Associate Dean David Rollock at the Graduate School (rollock@purdue.edu; 496-2775).

 

Upcoming important deadlines and information

 

Wed., Nov. 29:  Seminar for Neurotrauma and Diseases, 4:00 p.m., DLR 131. Koji Uchida, Professor of Food Chemistry, University of Tokyo will present ¡°Conversion of Proteins into DNA Mimetics by Reactive Aldehydes.¡± This seminar series is organized by the Center for Paralysis Research and supported by Plexon, the Purdue Institute for Integrative Neuroscience, and Purdue Institute for Drug Discovery. The Zoom link is: https://bit.ly/441Dllq. For additional information, see https://vet.purdue.edu/cpr/

 

Wed., Nov. 29: Telephone System Update Implemented, 7:00 p.m.  Purdue IT is completing the long-running project to retire the phone switch installed more than 25 years ago. Beginning after 7:00 p.m. EST, November 29, changes to the way you use the Purdue West Lafayette telephone systems will be required. See link below for details.

 

Fri., Dec. 1:  Indiana Human-Centered Design for Health Seminar Series, 12:00 p.m. via Zoom. Lean about research and best practices in HCD and health, promote the diverse HCD expertise in Indiana, and build a community of HCD researchers and practitioners focused on health, in Indiana and beyond. The speaker will be Jackie Linnes, Associate Professor of Biomedical Engineering at Purdue. Register and learn about upcoming seminars at healthtechquitylab.org/hcd-seminar

 

Fri., Dec. 1:  Indiana Life Sciences Conference – ¡°Closing the Gap[ of Health Inequalities,¡± 8:00 a.m. – 3:15 p.m., Roche Diagnostics, Indianapolis. See below for details.

 

Sun., Dec. 3: The Bilsland Dissertation Fellowship nominations due to Tammy Siemers (tsiemers@purdue.edu). See above for details.

 

Thurs., Dec. 14:  SAVE THE DATE: 2023 Senior Design Projects Expo and Awards Ceremony, 3:30-5:30 p.m., MJIS. Please mark your calendars and plan to join us to celebrate the achievements of our 2023 senior design teams. The expo will highlight 30 innovative engineering solutions, followed by a live awards ceremony.

 

Fri., March 1:  Indiana Human-Centered Design for Health Seminar Series, 12:00 p.m. via Zoom. Lean about research and best practices in HCD and health, promote the diverse HCD expertise in Indiana, and build a community of HCD researchers and practitioners focused on health, in Indiana and beyond. The speaker will be Andrew Miller, Associate Professor and Chair, Department of Hunan-Centered Computing, IUPUI. Register and learn about upcoming seminars at healthtechquitylab.org/hcd-seminar

 

Fri., June 7:  Indiana Human-Centered Design for Health Seminar Series, 12:00 p.m. via Zoom. Lean about research and best practices in HCD and health, promote the diverse HCD expertise in Indiana, and build a community of HCD researchers and practitioners focused on health, in Indiana and beyond. The speaker will be Youngbok Hon, Professor, Herron School of Art and Design, IUPUI. Register and learn about upcoming seminars at healthtechquitylab.org/hcd-seminar

 

Resources and further information

 

Wed., Nov. 15:  Weldon School of Biomedical Engineering Research Seminar, 9:30 a.m., MJIS 1001 or via Zoom. Jane Grande-Allen, PhD, Department of Bioengineering, Rice University, will present ¡°Biophysically Faithful Biomaterial Platforms for Cardiovascular and Intestinal Mechanobiology.¡±

Abstract: The material behavior of many biological tissues is due to their unique microstructural arrangements of fibrous extracellular matrix (ECM) proteins, i.e., collagen and elastin, within the more amorphous matrix. The orientation of these fibers, and their segregation into discrete regions within the tissues, often gives rise to anisotropy and unique biological stress-strain behavior that enables the essential function of the tissues. Layered or segregated structuring allow hierarchical tissue organization in a manner designed to withstand external forces efficiently while protecting more delicate tissues and cells from damage. These structure-function relationships within biological tissues have been studied for decades but have not been widely translated into the creation of biomimetic scaffolds for use in tissue engineering and in vitro analyses of cell and tissue biology. The Grande-Allen research group has focused on integrating these structural and material characteristics into hydrogel and fibrous biomaterials using a range of fabrication techniques including molding, photolithography, electrospinning, and 3D printing. The majority of our investigations have addressed heart valve disease, which is widely prevalent in our society, with valve replacement or repair in almost 100,000 people in the United States and 275,000 people worldwide each year. More recently, we have translated our fabrication strategies to generate biomaterial platforms for investigating intestinal epithelial cell biology and enteric diseases.

Biography: Jane Grande-Allen is the Isabel Cameron Professor of Bioengineering at Rice University.  Her research group investigates the structure-function-environment relationship of soft connective tissues through bioengineering analyses of the extracellular matrix and cell mechanobiology, with a focus on cardiovascular and intestinal diseases, as described in >180 peer-reviewed publications.  Dr. Grande-Allen received a BA in Mathematics and Biology from Transylvania University in 1991 and a PhD in Bioengineering from the University of Washington in 1998.  After postdoctoral research in Biomedical Engineering at the Cleveland Clinic, she joined Rice University in 2003 and was promoted to full professor in 2013. Dr. Grande-Allen is a Fellow of AIMBE, IAMBE, BMES, AAAS, AHA, and the Society for Experimental Mechanics. She served on the BMES Board of Directors and Executive Board from 2009-2022 and was BMES Secretary from 2020-2022. Dr. Grande-Allen also serves on the research committee for the American Heart Association.

 

~ BME Host: Deva Chan ~

NOTE: Students registered for the seminar are expected to attend in-person.

Zoom link: https://purdue-edu.zoom.us/j/95124789878?pwd=S0x0VW5Vd3VaMVc1LytlL0NJU1FYUT09

 

Thurs., Nov. 16: BME PhD Preliminary Exam Announcement for Elnaz Ghajar-Rahimi, (C. Goergen, advisor), 2:30 p.m., MJIS 2001 and via Zoom. Title: Cardiovascular remodeling due to volume and pressure overload.

Advisory Committee: Craig J. Goergen, Chair; Vitaliy L. Rayz; Fiona R. Kolbinger; Kyoko Yoshida; Benjamin J. Landis

Abstract: Volume and pressure overload induce cardiac remodeling that may lead to heart failure when left untreated. Conditions such as pregnancy, lactation, and aortic stenosis are common etiologies of pressure and volume overload. However, sex- and female-specific variables and recovery are often overlooked in studies of cardiac overload. One of the most common modalities used to study cardiac function, 2D ultrasound, does not fully capture changes that may occur to heart shape and performance given that it is limited to a single imaging plane. To improve our understanding of pressure and volume overload we propose mouse models of lactation, chronic hypertension with pregnancy, and reversible transverse aortic constriction. We hypothesize that four-dimensional ultrasound will reveal the unique ways in which volume and pressure overload in the setting of pregnancy, lactation, and aortic constriction affect cardiac remodeling. Completion of this study will broaden the horizons of maternal cardiac health and lay the framework for future exploration of sex as a biological variable in CVD studies.

Zoom link: https://purdue-edu.zoom.us/j/94088456640

Thurs., Nov. 16:  Seminars in Hearing Research, 12:00 noon, Nelson Hall, Room 1215. Andrew Sivaprakasam, MD/PhD Trainee, Indiana University School of Medicine will present ¡°Physiological and Perceptual Investigations of Place and Time Coding of Pitch Across Species: Preliminary Findings and Experimental Framework.¡±

Abstract:  An elusive empirical neural explanation for pitch perception has inspired several cochlear place and time-dependent hypotheses. Most experts debate the importance of tonotopy versus temporal coding, but it is still unclear how disruptions of these mechanisms are influenced by sensorineural hearing loss (SNHL). SNHL is complex, but as a diagnosis, it groups variable degrees of inner and outer hair cell (IHC/OHC) and cochlear synapse (CS) damage which likely results in different patterns of pitch perception. With careful stimulus design and electrophysiological data harmonization between animal and human subjects, we are developing a framework to more directly link alterations in neural coding to pitch perceptual outcomes. I will present progress related to my NRSA F30 project (Title: Place and Time Processing of Pitch in the Context of Cochlear Dysfunction), which was funded thanks to the fruitful discussions and feedback sparked by this seminar two years ago. Key progress so far includes data collection in several chinchillas and humans with normal hearing status, involving iteratively refined electrophysiological (EFR, ACC) and behavioral correlates (F0DL) of place and time coding.

This year¡¯s SHRP schedule is available here: https://purdue.edu/TPAN/hearing/shrp_schedule 

Titles and abstracts of all SHRP talks are here: https://purdue.edu/TPAN/hearing/shrp_abstracts

 

Fri., Nov. 17: BME PhD Preliminary Exam Announcement for Eugene S. Kim (T. Kinzer-Ursem, advisor). Everyone is invited to attend the public presentation beginning at 1:00 p.m. in MRGN 121. Title: ¡°The Role of CaMKII¥â-DrebrinA Binding in F-actin Stabilization in Dendritic Spines.¡±

Thesis Committee members: Dr. Tamara L. Kinzer-Ursem (Chair), Dr. Janice P. Evans, Dr. Fang Huang, Dr. Krishna Jayant

Abstract: Alzheimer¡¯s disease (AD) is a neurodegenerative disease often observed in elderly patients (¡Ã65y/o). Symptoms of AD include, but are not limited to, loss of learning and memory function and epileptic seizures. Symptoms of AD are rooted in dysfunctional synapses between neurons, leading to impaired synaptic plasticity. Several genes are associated with AD. For example, mutations in the gene encoding drebrin (DBN) are strongly implicated in AD. Drebrin1A (DBN1A) is an actin-stabilizing protein prominently expressed in dendritic spines and helps maintain the cytoskeletal structure. The role of DBN1A in structure-based synaptic plasticity has not been described. Dendritic spines are protrusions on the postsynaptic neuron and are composed of a spine head and spine neck. Although spine head enlargement is commonly seen in synaptic plasticity, an understanding of how the regions between the spine neck, head-neck interface, and spine head are regulated and its relation to synaptic plasticity is lacking. A recent discovery of DBN1A and CaMKII¥â interactions near this interface has been reported. However, it is still unclear how CaMKII¥â-DBN1A increases F-actin bundling in dendritic spines. Based on the literature, we suspect that CaMKII¥â-DBN1A binding plays a significant role in structure-based synaptic plasticity. We hypothesize that during synaptic plasticity, structural remodeling of dendritic spines requires CaMKII¥â-DBN1A to stabilize the F-actin pool at the head-neck interface. To test this hypothesis, we propose to use super-resolution microscopy (SRM) and molecular dynamic (MD) simulations to provide comprehensive evidence that CaMKII¥â-DBN1A complex is critical F-actin bundling during synaptic plasticity in dendritic spines.

 

Fri., Nov. 17:  BME PhD Defense Announcement for Tyler Diorio (V. Rayz, advisor). Everyone is invited to attend the public presentation beginning at 3:30pm in MJIS 2001 and via Zoom. Title of Thesis Research: Brain Biomechanics: Multiscale Mechanical Changes in the Brain and its Constituents.

Thesis Committee: Dr. Vitaliy Rayz (Chair), Dr. Yunjie Tong, Dr. Deva Chan, and Dr. Eric Nauman (School of Biomedical Engineering, University of Cincinnati, OH)

Abstract: The brain is a dynamic tissue that is passively driven by a combination of the cardiac cycle, respiration, and slow wave oscillations. The function of the brain relies on its ability to maintain a normal homeostatic balance between its mechanical environment and metabolic demands, which can be greatly altered in the cases of neurodegeneration or traumatic brain injury. It has been a challenge in the field to quantify the dynamics of the macroscale tissue and cerebrospinal fluid flow in human subjects on a patient-specific basis over the many spatial and temporal scales that it relies upon. Non-invasive imaging tools like structural, functional, and dynamic MRI sequences provide modern researchers with an unprecedented view into the human brain. Our work leverages these sequences by developing novel, open-source pipelines to 1) quantify the biomechanical environment of the brain tissue over 133 functional brain regions, and 2) estimate real-time cerebrospinal fluid velocity from the noise on functional MRI by employing breathing regimens to enhance fluid motion. These pipelines provide a comprehensive view of the macroscale tissue and fluid motion in a given patient. Additionally, we sought to understand how the transmission of macroscale forces, in the context of traumatic brain injury, contribute to neuronal damage by 3) developing a digital twin to simulate 30-200 g-force loading of 2D neuronal cultures and observing the morphological and electrophysiological consequences of these impacts in vitro by our collaborators. Taken together, we believe these works are a steppingstone that will enable future researchers to deeply understand the mechanical contributions that underly clinical neurological outcomes and perhaps lead to the development of earlier diagnostics, which is of dire need in the case of neurodegenerative diseases.

Zoom link: https://purdue-edu.zoom.us/j/98326783717

 

Wed., Nov. 29: Telephone System Update Implemented, 7:00 p.m.  Purdue IT is completing the long-running project to retire the phone switch installed more than 25 years ago. Beginning after 7:00 p.m. EST, November 29, the following changes to the way you use the Purdue West Lafayette telephone systems will be required.
1. Moving to utilize 10-digit dialing for all outgoing calls. This dialing method requires users to dial 1 + the area code of the person being called as part of the dialing process. However, 5-digit internal to campus dialing will remain the same.
This is a requirement dictated to use by our Carrier and is now standard nationwide. If you would like to know more about 10-digit dialing, the following website contains more information: https://www.fcc.gov/consumers/guides/ten-digit-dialing 

2. International Calling: The current process using international access codes will no longer be supported. If you currently have an international calling code and need the ability to dial internationally then please complete the form at: https://purdue.ca1.qualtrics.com/jfe/form/SV_1FVkar7IS9zKvjg 
Purdue IT strives to provide a top-quality telecommunications system and appreciates your support as we continue to upgrade our services and provide a highly reliable service. If you should have questions or concerns, please contact 
it@purdue.edu

 

Fri., Dec. 1:  Indiana Life Sciences Conference – ¡°Closing the Gap[ of Health Inequalities,¡± 8:00 a.m. – 3:15 p.m., Roche Diagnostics, Indianapolis.

 




Closing the Gap of
Health Inequalities

Friday, December 1
Roche Diagnostics, Indianapolis

Addressing the persistent disparities in health and wellness among different populations is an issue that can¡¯t be ignored. While the healthcare cost implications are significant, the societal and economic implications are even more so.

This conference will examine ongoing efforts to improve both the delivery of healthcare and health-related social factors like access to healthy foods, access to transportation and safe neighborhoods, which influence health outcomes.

 

 

AGENDA

 

8:00-9:00am

Registration & Breakfast

9:00-9:15am

Welcome & Introduction

9:15-10:15am

Opening Keynote- Defining Health Inequalities

Paul K. Halvorsen, Professor & Founding Dean, Richard M. Fairbanks School of Public Health, Indiana University

10:15-10:30am

Break

10:30am-12:00pm

Panel- Provider Perspective & Initiatives

Brownsyne Tucker Edmonds, M.D., Associate Professor of Obstetrics & Gynecology & Associate Dean for Health Equity Research, IU School of Medicine & VP Chief Health Equity Officer, IU Health

Edmond Davis, Senior Director, Health Equity, Zimmer Biomet

TBA

12:00-12:45pm

Break for Lunch

12:45-1:30pm

Luncheon Keynote- Snapshots of Ongoing Initiatives

Paige Bingham, Director, Close the Gap

Ariana McGee, Founder & CEO, Navigate Maternity

Holly Wood, Senior Director, Health Equity Initiative, Purdue University

TBA

1:30-3:00pm

Panel- Payer Perspective & Initiative

Antoniette Holt, Strategic Equity Officer & Division Director, Office of Minority Health, Indiana Department of Health

Darryl Lockett, Health Equity Director, Anthem Indiana Medicaid

Andy Vector, President of Benefits Consulting & Chief Growth Officer, MJ Insurance

TBA

3:00-3:315pm

Wrap-Up

 

 

 

 

BME Weekly Research Seminars

 

Week #

Date

Speaker

Title

Host

Website

13

11/15/2023

Jane Grande- Allen

Isabel C. Cameron Professor of Bioengineering, Rice University

Deva Chan

https://profiles.rice.edu/faculty/k-jane-grande-allen

14

11/29/2023

Sarah Wiehe

Jean and Jerry Bepko Professor of Pediatrics Indiana University School of Medicine

George Wodicka

https://medicine.iu.edu/faculty/16722/wiehe-sarah

15

12/6/2023

Robbee Wedow

Assistant Professor of Sociology and Data Science,
Purdue University Department of Sociology

David Umulis

https://www.robbeewedow.com/?_ga=2.88497945.389094989.1679581193-1816225309.1603576015

 

Postdoctoral Fellow Opportunity – IUSM Emergency Medicine

 

The laboratory of Dr. Nathan J. Alves, PhD, within the Department of Emergency Medicine at the Indiana University School of Medicine (IUSM), is seeking a highly motivated and independent post-doctoral research fellow. Dr. Alves is a Chemical and Biomolecular Engineer, Associate Professor and the Director of Translational Research for the Department of Emergency Medicine in addition to having an affiliate faculty appointment at Purdue University in Biomedical Engineering. The Alves Lab explores highly interdisciplinary research interests applying engineering and biophysical principles and designs to create translational technologies and treatments in the area of blood coagulation and fibrinolysis. The primary focus of research in the laboratory is to develop targeted clot digesting therapeutic agents to more safely digest clinically relevant blood clots to treat pulmonary embolism (PE, blood clots in the lungs), deep vein thrombosis (DVT), and ischemic stroke. This interdisciplinary research utilizes diverse enzyme assays, chemical synthesis, blood clot formation and digestion assays under shear, and other novel testing/delivery platforms that include multivalent branched molecules and nanoparticle drug delivery systems. Projects Include: (1) Leveraging multivalency to modulate enzyme activity and improve inhibitor selectivity (nanoparticle drug delivery and targeting). (2) Ex-vivo flowing models of clot digestion under shear using in-vivo like fluorescently labeled blood clots from human whole blood. (3) Development of novel fibrinolytic diagnostics tools to assess coagulation state. (4) Mouse models of clot formation/targeting/digestion utilizing intravital microscopy. (5) Study the effects of environmental microplastic exposure on coagulation/fibrinolysis. Projects are funded both externally and internally.

For additional information and to apply, go to: https://indiana.peopleadmin.com/postings/19651