BME MONDAY ROUNDTABLE

JANUARY 30, 2023

 

DEPUTY HEAD’S NOTE

 

Dear members of the Weldon School community,

 

Weeks ago, I was approached by Dr. David Umulis, about stepping in as the Deputy Head as he transitions to the role of Senior Vice Provost. I was surprised by the offer. I am humbled to have this opportunity to serve the Weldon School, its faculty, staff, and students. I am determined to support you in all fronts of discovery, teaching, and engagement, and all matters that are essential to your professional success. I am determined to helping provide an environment for the good health and wellbeing of all of you including your graduate students. Under the leadership of David, Young, and Tami, as well as the diligent and effective work from all of you, the School is under a positive trajectory over the past few years. So overall, I, as the Deputy Head, will make sure to represent the continuity and stability internally to all members of the school, and facing outward to the college, the university, the research communities, and all our partners.   

 

Nan Kong

Professor of Biomedical Engineering

 

 

UPCOMING IMPORTANT DATES

 

Week of January 30

Mon., Jan. 30:  Center for Diabetes and Metabolic Diseases Research Seminar, 12:00 p.m. via Zoom. Linda A. DiMeglio, MD, MPH, Professor of Pediatrics, Riley Hospital for Children and Director of Type 1 Diabetes Research Team will present “Circadian Mechanisms in Diabetes.” Zoom link: https://iu.zoom.us/j/83951671092?pwd=WC9GNTJaVTRVcEIyako4cHMvN2FXZz09 (Password: 629133)

Tues., Jan. 31, 10:00-10:30 a.m. and Thurs., Feb. 2, 1:30-2:00 p.m.: Purdue Travel Info Sessions. Employees traveling on official university business who do not have a Purdue University Travel Card (TCard), which may include infrequent travelers, graduate students and undergraduate students with paid appointments, will be able to make airfare reservations in Concur using a new Purdue Airfare Card beginning Jan. 23. Purdue Travel will host information sessions to provide a card overview and answer questions. Registration is now open.

Wed., Feb. 1:  Prospective BME Faculty Seminar, 9:30 a.m. in MJIS 1001 and via Zoom. Wei Ouyang, Postdoctoral Fellow, Bioelectronics, Northwestern University will present “Integrated Bioelectronic Systems for Biomedical Research and Healthcare: Materials, Electronics, and Computing.” (Note:  Students registered for credit for the seminar are expected to attend in-person.)

Thurs., Feb. 2:  Seminars in Hearing Research at Purdue (SHRP), 10:30 a.m., LYLE 1150 and via Zoom. Joshua Alexander, Associate Professor of SLHA will speak on “Evaluating the Efficacy of Music Programs in Hearing Aids.” Hearing aid processing of music is much less thoroughly researched than hearing aid processing of speech.  This presentation will report on a study using normal-hearing listeners that evaluated the efficacy of programs specifically designed for music listening in state-of-the-art hearing aids.  In addition, an analysis of signal processing and acoustic features relating to the results will be presented. Following this presentation, attendees will be able to: 1) Describe how hearing aids may negatively impact music perception;   2) Describe key features of real or hypothetical music programs for hearing aids; 3) Describe the efficacy of current music programs in hearing aids.

Zoom link for remote attendees: https://purdue-edu.zoom.us/j/4326340458 Meeting ID: 432 634 0458

Thurs., Feb. 2: Science on Tap, 6:00 p.m., Lafayette Brewing Company, 622 Main Street, Lafayette. Luis Solorio, Assistant Professor of Biomedical Engineering, will present “Spreading Cells: A Hitchhiker’s Guide to Megastasis.” Join us for “an informal conversation about science.” Age 21+.

Fri., Feb. 3:  The Great Lakes NSF I-Corps Hub and Purdue I-Corps are offering various workshops in Spring 2023 that can significantly increase the chances of securing federal proof of concept & commercialization grants like SBIR/STTR, PFI-TT that range from $500k to $1.6 million. The historical success rate for Purdue Faculty, who complete the NSF I-corps workshops, and apply for these competitive NSF research commercialization grants is over 90%. Please find details of the workshops below. 

STEM Jumpstart: Feb 3 – March 24 

Medical Jumpstart: Feb 3 – March 24 

Purdue I-Corps Discovery, Discovery+: Feb 17-March 24; March 31-April 7 

Gain new insights about your research, explore the commercial potential, learn about NSF funding opportunities, and increase your industry and professional network. Learn from our NSF-certified instructors, experienced entrepreneurs, and mentors. 

If a student/Post-doc in your lab is interested in this opportunity and would like to learn more, please reach out to Geetali Pradhan at gpradhan@purdue.edu

 

Upcoming important deadlines and info.

Mon., Feb. 6: BME PhD defense announcement for Sean M. Rothenberger (V. Rayz, advisor), 3:00 p.m., MJIS 2001 and via Zoom. Title of presentation: Statistical Models of 4D flow MRI Velocity Error using Principles of Fluid Dynamics and Imaging Physics

Wed., Feb. 8: Prospective BME Faculty Seminar, 9:30 a.m. in MJIS 1001 and via Zoom. Yiyang Gong, Assistant Professor of Biomedical Engineering, Duke University will present “Traditional and computational development of fluorescence imaging tools for neuroscience.” (Note:  Students registered for credit for the seminar are expected to attend in-person.)

Fri., Feb. 17:  Clinical and Translational Sciences (CTSI) Winter Retreat, 9:30 a.m. – 3:00 p.m., Purdue University West Lafayette campus, Hall for Discovery Learning and Research, Room 131. Agenda includes:

·      Introduction from Indiana CTSI

·      Keynote Speakers on women's health research

·      Discussion panels including topics on:

o    Maternal and child health

o    Obesity and chronic diseases

o    Neurodegenerative disorder and aging

o    Women's health in rural areas

Full agenda and registration links at https://engineering.purdue.edu/BME/CTSI/Winter-Retreat . This event is sponsored by the Purdue University Women’s Global Health Institute and the Indiana CTSI. Registration closes February 14.

 

PURDUE ADVERSE WINTER WEATHER POLICY

If adverse weather conditions necessitate that a wind chill, snow or ice emergency be declared for the West Lafayette campus, special procedures pertaining to classes, operations, parking, pay and/or attendance will become effective. Jay Wasson, vice president for physical facilities and chief public safety officer, describes procedures for adverse winter weather in this memo.

 

Committee Updates

 

Graduate Office Update

 

Spring 2023 BME Seminar Schedule (Wednesdays, 9:30 a.m. in MJIS 1001). Full schedule below.

 

New Course for Fall 2023:  BME 69500 Pediatric Medical Devices (CRN 14011). Details below.

 

Awards season is upon us and we will be asking for several nominations with varying deadlines over the next month.  Below is a quick snapshot of all those awards and deadlines.  More detailed emails for each award will be sent separately that will list the criteria and materials needed for the nomination. Two of them look similar (Dissertation and Outstanding Graduate Researcher) so we wanted to make sure that you knew they were actually two separate awards.

Let me know if you have any questions (tsiemers@purdue.edu).

 

Graduate Admissions Update

 

Fall 2022 (Fall 2023 Admit Term) BME Graduate Admissions

DateDATE

Activity

Feb 2-4

Weldon School Visitation Days (Hybrid)

Feb 8

Last chance for Research Areas / Faculty to remove students from fellowship consideration

Feb 10

Fellowship offers announced and complete rankings list made available to BME faculty; BME Graduate Office will notify students by email (offer letters distributed as soon as signed by BME Head and COE Dean)

Mar 10

DUE: All Master’s students to be decisioned as either admit, deny or hold

Mar 31

Due: All PhD students to be decisioned as either admit, deny or hold

April 15

Graduate applicant acceptance deadline

 

 

BME Faculty Search Update

 

The Faculty Search Committee has invited four faculty candidates to campus for interviews. If you are interested in meeting with any of the candidates, please contact Jo Gelfand (jo@purdue.edu). All candidates will give a research seminar in MJIS 1001 at 9:30 a.m. on the Wednesday of their visit.

Jan. 18-19 – Jacob Rosenstein, Associate Professor of Engineering, Brown University

Jan. 25-26 – Sunghee Estelle Park, PhD Candidate and CEMB Fellow, Bioengineering, Univ. of PA

Feb. 1-2 – Wei Ouyang, Postdoctoral Fellow, Bioelectronics, Northwestern Univ.

Feb. 8-9 – Yiyang Gong, Assistant Professor of Biomedical Engineering, Duke Univ.

 

 

Resources and further information

Purdue Travel Info Session. Tues., Jan. 31, 10:00-10:30 a.m. and Thurs., Feb. 2, 1:30-2:00 p.m., Employees traveling on official university business who do not have a Purdue University Travel Card (TCard), which may include infrequent travelers, graduate students and undergraduate students with paid appointments, will be able to make airfare reservations in Concur using a new Purdue Airfare Card beginning Jan. 23. Purdue Travel will host information sessions to provide a card overview and answer questions. Registration is now open.

Travelers will not physically receive a Purdue Airfare Card, as it is automatically loaded into a user’s Concur profile. Anyone with a Concur profile will have the ability to charge airfare on the card. The booking process in Concur will not change, and there is no special action that needs to be taken to use the new card.  The Purdue Airfare Card can only be used when self-booking airline reservations through Concur. The card may not be used when booking through third-party services or AAA Corporate Travel, Purdue’s partnering travel agency. If a traveler tries to book a hotel and/or car rental at the same time, the system will prompt for an additional personal card to be used for those accommodations. When compiling a travel expense report, the airfare charge will be waiting in the traveler’s unassigned expenses with a payment type of “PU Airfare Card” and needs to be added to the traveler’s expense report after travel. Travelers that have a TCard should continue to use their card for travel-related expenses. TCard holders need to select “Corporate Card” from the payment drop-down menu when confirming their airfare selection in Concur, otherwise the PU Airfare Card will be the automatic payment default for air expense.  A Quick Reference Guide is available to help travelers book airfare with the Purdue Airfare Card. Questions may be directed to Purdue Travel at 765-494-7354 or purduetravel@purdue.edu.

 

Prospective BME Faculty Seminar, Wed., Feb. 1, 9:30 a.m. in MJIS 1001 and via Zoom. Wei Ouyang, Postdoctoral Fellow, Bioelectronics, at Northwestern University will present “Integrated Bioelectronic Systems for Biomedical Research and Healthcare: Materials, Electronics, and Computing.”

Abstract: Probing and modulating life processes in the native state represents a key capability in our quest for a better understanding of life and a higher quality of life. In this talk, I will present implantable and wearable forms of flexible bioelectronic devices developed through a systems approach combining materials, electronics, and computing that open up new opportunities for fundamental biomedical research in unperturbed, naturally behaving animal models and for continuous, ambulatory monitoring of human health. I will first present a new class of wireless, battery-free, fully implantable devices that offer multimodalities and closed-loop functionalities in neuroscience research and the use of this technology for studying auditory-evoked potentials, sleep-wake regulations, seizure treatment, cardiology, and social interactions. Then I will present the translation of this technology in human healthcare using a wearable mechano-acoustic sensing device deployed to about 500 patients as an example, with an emphasis on data analytics for continuous monitoring of COVID-19 and vocal health. I will conclude by discussing future opportunities of my research in both fundamental and translational biomedicine.

 

Bio: Wei Ouyang is currently a postdoctoral fellow supervised by Prof. John A. Rogers at the Querrey Simpson Institute for Bioelectronics, Northwestern University. He received his S.M. degree in Electrical Engineering and Computer Science and Ph.D. degree in Electrical Engineering from the Massachusetts Institute of Technology under the supervision of Prof. Jongyoon Han. He received his B.S. degree in Microelectronics from Peking University, China. His research interests include implantables, wearables, neural engineering, digital health, bioMEMS, and microfluidics. He is a recipient of several prestigious awards, including the Dimitris N. Chorafas Foundation Award, Siebel Scholar (Class of 2016), the Peake Research Prize at MIT, and the Ernst A. Guillemin Thesis Award at MIT.

~BME Host: Hugh Lee~

Zoom link: https://purdue-edu.zoom.us/j/91331613591?pwd=dnY3M1pqTXVVZGdOeklpc2pSR0svUT09&from=addon

 

The Great Lakes NSF I-Corps Hub and Purdue I-Corps are offering various workshops in Spring 2023 that can significantly increase the chances of securing federal proof of concept & commercialization grants like SBIR/STTR, PFI-TT that range from $500k to $1.6 million. The historical success rate for Purdue Faculty, who complete the NSF I-corps workshops, and apply for these competitive NSF research commercialization grants is over 90%. Please find details of the workshops below. 

STEM Jumpstart: Feb 3 – March 24 

Medical Jumpstart: Feb 3 – March 24 

Purdue I-Corps Discovery, Discovery+: Feb 17-March 24; March 31-April 7 

Gain new insights about your research, explore the commercial potential, learn about NSF funding opportunities, and increase your industry and professional network. Learn from our NSF-certified instructors, experienced entrepreneurs, and mentors. 

If a student/Post-doc in your lab is interested in this opportunity and would like to learn more, please reach out to Geetali Pradhan at gpradhan@purdue.edu

 

 

Purdue I-Corps 

Great Lakes hub I-Corps (Jumpstart) 

 

Discovery 

Discovery+ 

STEM specific 

Medical specific 

Duration 

4 workshops 

2 workshops 

5 workshops 

5 workshops 

Schedule 

Feb 17 – March 24, online 

March 31, April 7, online 

Feb 3 – March 24, online 

Feb 3 – March 24, online 

Team requirement

2-4

2-4

2-4

Affiliation 

Purdue Univ, any Midwest Univ 

Purdue Univ, any Midwest Univ 

Hub-affiliated institutions and other Midwest teams 

Hub-affiliated institutions and other Midwest teams 

Prerequisite 

None 

Discovery 

None 

None 

Instructors 

2-3 

2-3 

3-6 

3-6 

Learnings 

Customer Discovery, Product-Market Fit, and Market Assessment 

Market size, Commercialization pathway, Commercialization grants 

Customer Discovery, Product-Market Fit, Market Assessment, Commercialization Pathway 

Customer Discovery, Product-Market Fit, Market Assessment, Commercialization Pathway 

Learn more 

Purdue I-Corps 

STEM Jumpstart 

Medical Jumpstart 

 

 

BME PhD defense announcement for Sean M. Rothenberger, Mon., Feb. 6, 3:00 p.m., MJIS 2001 and via Zoom. Title of presentation: Statistical Models of 4D flow MRI Velocity Error using Principles of Fluid Dynamics and Imaging Physics. Everyone is invited to attend the public presentation.

Advisory Committee: Vitaliy L. Rayz, Chair; Pavlos P. Vlachos; Craig J. Goergen; Michael Markl

Abstract: 4D flow magnetic resonance imaging (MRI) has emerged as an imaging modality capable of assessing cardiovascular flow non-invasively. Despite interest in using these in vivo measurements for cardiovascular disease diagnostics and progression assessment, there are no adequate models of 4D flow MRI’s measurement error. Error models are essential in evaluating accurate hemodynamic biomarkers and judging the quality of 4D flow MRI scans. Here, we present a comprehensive error model of 4D flow MRI velocity measurements using fluid dynamics and imaging physics principles. 4D flow MRI velocity error is described as a multivariate normal distribution which is a function of space and time. The error distribution’s scale is assessed using the principle of conservation of mass, and error correlations are assessed using the novel standardized difference of means (SDM) velocity metric. We define the SDM velocity as the difference between the local mean velocity and the global background mean velocity relative to the standard error of the local mean velocity. We also demonstrate the SDM velocity’s utility in segmenting vessels in 4D flow MRI measurements. This work also introduces a bias error model, which accounts for insufficient spatial resolution and partial volume effects. These bias error estimates serve as one means of validating our proposed 4D flow MRI error model. All algorithms presented are validated in 4D flow MRI measurements in scaled in vitro cerebral aneurysms and in vivo 4D flow measurements. This work ultimately supports the development of reliable biomarkers indicative of cardiovascular disease progression.

Zoom link: https://purdue-edu.zoom.us/j/99467282487

 

Prospective BME Faculty Seminar, Wed., Feb. 8, 9:30 a.m. in MJIS 1001 and via Zoom. Yiyang Gong, Assistant Professor of Biomedical Engineering, Duke University will present “Traditional and computational development of fluorescence imaging tools for neuroscience”

Abstract: Modern basic research in neuroscience aims to dissect neural activity from genetically identifiable neuron populations within dense neural circuits. Such research has relied increasingly on tools that perform optical imaging and optical stimulation. In this area, my lab develops a diverse toolbox that employs multiple engineering disciplines simultaneously. In this talk, I will highlight our recent gains in protein engineering, optical microscopy, and data analysis. The protein tools will attempt to enable multi-channel optical experiments by increasing spectral separation between fluorescent protein sensors and actuators. The microscopy tools will attempt to support fast volumetric imaging experiments that accurately capture neural activity. The data analysis tools will attempt to find neurons and calculate their neural activity from the large datasets resulting from optical imaging experiments quickly and accurately. Lastly, this talk will touch on the future of the protein engineering pipeline seen through the lens of protein tools in neuroscience.

Bio: Yiyang Gong obtained his B.S. in Electrical Engineering from the California Institute of Technology. He then obtained his M.S. and Ph.D. in Electrical Engineering from Stanford University, training with Prof. Jelena Vuckovic on plasmonic and photonic crystal optical devices. He trained with Prof. Mark Schnitzer at Stanford University as a postdoc in Biology, developing genetically encoded voltage sensors that are advancing the current generation of neuroscience experiments. His current work focuses on imaging neural activity with a combination of engineered protein sensors, optical microscopes, and computational algorithms. His work has been supported by the Beckman Young Investigator Award, the BRAIN initiative, NIH New Innovator Award, NSF CAREER Award, Sloan Fellowship, and Vallee Young Investigator Award.

~BME Host: Hugh Lee~

Zoom link: https://purdue-edu.zoom.us/j/97275864534?pwd=UFNhaDBadVVxRjVxdE5UOTRlT0trUT09&from=addon

 

New Course for Fall 2023:  BME 69500 Pediatric Medical Devices (CRN 14011).

Fall 2023, 3.0 credit hours

Wednesdays 11:30-2:20 in MJIS 1083 (in person attendance only)

Prerequisite: BME Graduate Standing

Course Description: The unique medical needs of pediatric patients in the context of current and emerging clinical technologies are presented in this novel course. Anatomical, physiological, and pathophysiological underpinnings of diseases in infants and children are studied. Unique aspects of pediatric device design, regulation, and translation, including clinical studies and ethical considerations, are explored. Numerous clinical sub specialties such as cardiology, surgery, nephrology, pulmonology, and gastroenterology are examined in terms of technology adoption and remaining clinical needs. Future directions in device development and emerging trends in patient care are considered throughout.

Weekly Course Topics:

August 23            Pediatrics Introduction

August 30            Neonatology Introduction

September 6      Pediatric Device Design and Development I

September 13    Pediatric Device Design and Development II

September 20    Pediatric Device Regulation

September 27    Pediatric Clinical Studies

October 4            Pediatric Cardiology

October 18          Pediatric Cardiovascular Surgery

October 25          Pediatric Nephrology

November 1       Pediatric Pulmonology

November 8       Pediatric Wound Healing

November 15     Pediatric Gastroenterology

November 29     Ethical Considerations in Pediatrics

December 6        Future Directions and Trends

Primary Instructor: George Wodicka, MJIS 3036, wodicka@purdue.edu

Numerous experts from the Indiana University School of Medicine Department of Pediatrics, Riley Hospital for Children, and Cook Medical, Inc. will actively participate.

 

Spring 2023 BME Seminar Schedule (Wednesdays, 9:30 a.m. in MJIS 1001)

 

Week

 

Date

Speaker

Host

 

Week 4

2/1/2023

Faculty candidate

Dr. Wei Ouyang, Postdoctoral Fellow, Bioelectronics, Northwestern University

Dr. Hugh Lee

 

Week 5

2/8/2023

Faculty candidate

Dr. Yiyang Gong, Assistant Professor of Biomedical Engineering, Duke University

Dr. Hugh Lee

 

Week 6

2/15/2023

Dr. Ken Yoshida

Professor of BME at IUPUI

Dr. Young Kim

Week 7

2/22/2023

Dr. Rita Patel

Associate Professor, Speech & Hearing Sciences + Associate Professor of Otolaryngology-Head & Neck Surgery at IUSM

Dr. Young Kim

Week 8

3/1/2023

Dr. Joey Wallace

Chair and Professor of BME at IUPUI

Dr. Young Kim

Week 9

3/8/2023

Dr. Hubert Lim

Professor, Department of Biomedical Engineering, Otolaryngology, Institute for Translational Neuroscience Scholar, University of Minnesota

Dr. Hugh Lee

Week 10

3/22/2023

Dr. Daniel DiLorenzo, Assistant Professor, Neurosurgery and Biomedical Sciences, Loma Linda University; Attending Neurosurgeon, Loma Linda VA Medical Center; President Barinetics Corporation

Dr. Matthew Ward

Week 11

3/29/2023

Dr. Nimmi Ramanujam

Robert W. Carr Professor of Biomedical Engineering, Department of Pharmacology and Cell Biology, Director of The Center for Global Women's Health Technologies, Duke University

Dr. Jackie Linnes

Week 12

4/5/2023

Dr. Junhong Chen

Crown Family Professor of Molecular Engineering and Lead Water Strategist at Argonne National Laboratory

Dr. Chi Hwan Lee

Week 13

4/12/2023

Dr. Chien-Chi Lin

Thomas J. Linnemeier Guidant Foundation Endowed Chair & Professor of BME at IUPUI

Dr. Young Kim

Week 14

4/19/2023

Dr. Rachel Surowiec

Assistant Professor of BME at IUPUI

Dr. Young Kim

Week 15

4/26/2023

Dr. James Moon

J. G. Searle Professor, Pharmaceutical Sciences Professor, Biomedical Engineering at Michigan

Dr. Chi Hwan Lee

The titles and abstracts of the talks will be added here: https://purdue.edu/TPAN/hearing/shrp_abstracts

 

Attachments

2023 CTSI Winter Retreat Flyer v2.pdf