BME PhD Preliminary Exam Announcement for Aditya Shanghavi (A. Sereno and B. Duerstock, co-advisors)

Everyone is invited to attend the public presentation beginning at 1:30 pm.

Title: A Study of Tremor in Parkinson’s Disease Using Signals From Wrist-Worn IMU Sensors

Date: 12/06/2022

Time: 1:30 pm

Location: MJIS 2001

Virtual Link: https://purdue-edu.zoom.us/j/4520252995

Advisory Committee:

Anne B. Sereno, Co-Chair

Bradley S. Duerstock, Co-Chair

Craig J. Goergen

Satyajit S. Ambike

Abstract: Parkinson’s Disease (PD) is the second most common neurodegenerative disorder with

resting tremor (RT) being its most common motor symptom. The literature has revealed

that the need for lengthy, clinic-based subjective evaluation by trained neurologists of

treatment effects in PD creates challenges for monitoring the progression of the disease and

titrating optimal therapeutic therapies. Preliminary studies have shown that features of

a power spectral density (PSD) analysis of wrist velocity and acceleration can be used as

objective, reliable, and sensitive detectors of RT. Replacing the neurologist’s judgement

on the progression of the disease is not feasible, yet some aspects of tracking the disorder

and treatment may profit from more frequent remote sensor measurements. There is an

opportunity to improve patient-care by introducing non-invasive, sensor-based objective

measurements of RT using wrist movements that can aid the neurologist with the MS-

UPDRS evaluation in the diagnostic process. Success in objectively quantifying RT with

such a method would allow physicians to more frequently and remotely monitor patients

to change the treatment plan as needed to reduce the severity of harmful side effects of

PD medication.